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The map label for this gene is phoP [H]

Identifier: 158334336

GI number: 158334336

Start: 1125246

End: 1126373

Strand: Reverse

Name: phoP [H]

Synonym: AM1_1157

Alternate gene names: 158334336

Gene position: 1126373-1125246 (Counterclockwise)

Preceding gene: 158334339

Following gene: 158334334

Centisome position: 17.32

GC content: 45.04

Gene sequence:

>1128_bases
ATGGTGAAAATTCTGATCATCGATGATGATCCCATTACCCAGCTCCTCTTACGCCGCACACTTGAAAAACAGGGGTATCA
GGTGACTGTCGCCAGCGATGGTCAAGAAGGCCTCTCAAAGGCACAGCAACTCTGCCCTGCCTTAATCATCTGCGATTGGA
TGATGCCGGTATTGGATGGGATTGGTGTTTGTCAGCAATTAAAATCAAATCCACAACTTTCTGCCACTTTTTTTATTTTG
TTAACGTCTCGATCTGATCTGGAAGATCGAATTGCTGGACTGAATGCTGGGGCTGATGAATTTCTAACAAAACCCATTGA
TATGAGTGAACTGCGGGCCCGTGTGCGGGCAGGGCTGAGGCTCTATCACTTAAACCAGGACTTACACGAACAAAAACAAA
GGCTGGAAGCGGAATTGGCAGAGGCTGCCCAATATGTTCGTTCCATTTTGCCTGCCCCCTTACAATCGCCGATTCAAATC
CAGTCCCGGTTTATTCCATCTAGTCAATTAGGTGGGGATTGCTTTGATTACTATTGGTTAACCCCAGATACGTTGATTTT
GTATCTGTTGGATGTGTCAGGGCATGGTTTGGGGGCAGCCTTGCCGTCGGTATCAATATTGAATATGTTGCGATCGCAAG
CATTCCCAGGCATCAATTACCAACATCCCCATGAAGTGTTGCACGCTCTCAATCAACGATTCACCATGAGCCCCGAAAAC
CCTAAATACATCACCATTTGGTATGGGGTTTATCATCGCTCTCGTCAAGAATTAGTATTTTCCAGTGCCGGGCATCCGCC
AGCCCTATTGATGTCAACATCAGAACCAGAGGTACAGACCTTAAAAACACCAGGACTTCCCTTGGGTATGTTTGCAGAAT
TTACCTATCAAAGTCAGAGCTGTAACATCACGCCACATCAAACTCTCTATATCTTTAGCGATGGGATTTATGAAATTCCT
AAAACCAACAATCAACTGCTGGGGCTAGAAGGATTCTCCCATGTACTCCAACAGCTTCATCAAATAGGATCCCCCACAAT
TGAAACTATTTTGGACCAAGTACAAATATGTTGTAAGCACCAGCGCTTTACAGATGATTTATCCCTGATGCAAGTTGTCT
TTCCGTAA

Upstream 100 bases:

>100_bases
CAGAGATTATCCCCTTGCTAAACTTGAACAGTGTGGATTAGCCCTCGCCCTTGCGAATAAATTCACAATAGATGATCAAA
TATGGCCTTGTGAAACATCT

Downstream 100 bases:

>100_bases
GTACCGCCTGAAAACTAGAACTTCAAGAACCTAAAAGCCCACTTTGTTCGAAATGTTGCCGATTGTCGTAGATCTGAAAC
ACTTGAGCGATTTCAGTCAA

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MVKILIIDDDPITQLLLRRTLEKQGYQVTVASDGQEGLSKAQQLCPALIICDWMMPVLDGIGVCQQLKSNPQLSATFFIL
LTSRSDLEDRIAGLNAGADEFLTKPIDMSELRARVRAGLRLYHLNQDLHEQKQRLEAELAEAAQYVRSILPAPLQSPIQI
QSRFIPSSQLGGDCFDYYWLTPDTLILYLLDVSGHGLGAALPSVSILNMLRSQAFPGINYQHPHEVLHALNQRFTMSPEN
PKYITIWYGVYHRSRQELVFSSAGHPPALLMSTSEPEVQTLKTPGLPLGMFAEFTYQSQSCNITPHQTLYIFSDGIYEIP
KTNNQLLGLEGFSHVLQQLHQIGSPTIETILDQVQICCKHQRFTDDLSLMQVVFP

Sequences:

>Translated_375_residues
MVKILIIDDDPITQLLLRRTLEKQGYQVTVASDGQEGLSKAQQLCPALIICDWMMPVLDGIGVCQQLKSNPQLSATFFIL
LTSRSDLEDRIAGLNAGADEFLTKPIDMSELRARVRAGLRLYHLNQDLHEQKQRLEAELAEAAQYVRSILPAPLQSPIQI
QSRFIPSSQLGGDCFDYYWLTPDTLILYLLDVSGHGLGAALPSVSILNMLRSQAFPGINYQHPHEVLHALNQRFTMSPEN
PKYITIWYGVYHRSRQELVFSSAGHPPALLMSTSEPEVQTLKTPGLPLGMFAEFTYQSQSCNITPHQTLYIFSDGIYEIP
KTNNQLLGLEGFSHVLQQLHQIGSPTIETILDQVQICCKHQRFTDDLSLMQVVFP
>Mature_375_residues
MVKILIIDDDPITQLLLRRTLEKQGYQVTVASDGQEGLSKAQQLCPALIICDWMMPVLDGIGVCQQLKSNPQLSATFFIL
LTSRSDLEDRIAGLNAGADEFLTKPIDMSELRARVRAGLRLYHLNQDLHEQKQRLEAELAEAAQYVRSILPAPLQSPIQI
QSRFIPSSQLGGDCFDYYWLTPDTLILYLLDVSGHGLGAALPSVSILNMLRSQAFPGINYQHPHEVLHALNQRFTMSPEN
PKYITIWYGVYHRSRQELVFSSAGHPPALLMSTSEPEVQTLKTPGLPLGMFAEFTYQSQSCNITPHQTLYIFSDGIYEIP
KTNNQLLGLEGFSHVLQQLHQIGSPTIETILDQVQICCKHQRFTDDLSLMQVVFP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=137, Percent_Identity=41.6058394160584, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786911, Length=122, Percent_Identity=40.9836065573771, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786599, Length=118, Percent_Identity=33.8983050847458, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1789809, Length=118, Percent_Identity=37.2881355932203, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787487, Length=322, Percent_Identity=27.3291925465839, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI2367329, Length=126, Percent_Identity=39.6825396825397, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1787229, Length=113, Percent_Identity=36.283185840708, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788394, Length=129, Percent_Identity=32.5581395348837, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1786784, Length=119, Percent_Identity=36.1344537815126, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788550, Length=133, Percent_Identity=27.8195488721804, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1790437, Length=123, Percent_Identity=30.8943089430894, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790863, Length=113, Percent_Identity=33.6283185840708, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787375, Length=119, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790860, Length=211, Percent_Identity=30.8056872037915, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1790552, Length=129, Percent_Identity=35.6589147286822, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1788191, Length=115, Percent_Identity=28.695652173913, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790299, Length=124, Percent_Identity=29.8387096774194, Blast_Score=61, Evalue=1e-10,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 42132; Mature: 42132

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKILIIDDDPITQLLLRRTLEKQGYQVTVASDGQEGLSKAQQLCPALIICDWMMPVLDG
CEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVCQQLKSNPQLSATFFILLTSRSDLEDRIAGLNAGADEFLTKPIDMSELRARVRAGLR
HHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCEE
LYHLNQDLHEQKQRLEAELAEAAQYVRSILPAPLQSPIQIQSRFIPSSQLGGDCFDYYWL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEE
TPDTLILYLLDVSGHGLGAALPSVSILNMLRSQAFPGINYQHPHEVLHALNQRFTMSPEN
CHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEECCCCC
PKYITIWYGVYHRSRQELVFSSAGHPPALLMSTSEPEVQTLKTPGLPLGMFAEFTYQSQS
CCEEEEEEECHHCCHHHHHHHCCCCCCEEEEECCCCCHHEECCCCCCHHHHHHHEECCCC
CNITPHQTLYIFSDGIYEIPKTNNQLLGLEGFSHVLQQLHQIGSPTIETILDQVQICCKH
CCCCCCCEEEEEECCCEECCCCCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QRFTDDLSLMQVVFP
CCCCCHHHHHHHHCC
>Mature Secondary Structure
MVKILIIDDDPITQLLLRRTLEKQGYQVTVASDGQEGLSKAQQLCPALIICDWMMPVLDG
CEEEEEECCCHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IGVCQQLKSNPQLSATFFILLTSRSDLEDRIAGLNAGADEFLTKPIDMSELRARVRAGLR
HHHHHHHHCCCCCEEEEEEEEECCCCHHHHHHCCCCCHHHHHCCCCCHHHHHHHHHHCEE
LYHLNQDLHEQKQRLEAELAEAAQYVRSILPAPLQSPIQIQSRFIPSSQLGGDCFDYYWL
EEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCCEEEEEEE
TPDTLILYLLDVSGHGLGAALPSVSILNMLRSQAFPGINYQHPHEVLHALNQRFTMSPEN
CHHHEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEECCCCC
PKYITIWYGVYHRSRQELVFSSAGHPPALLMSTSEPEVQTLKTPGLPLGMFAEFTYQSQS
CCEEEEEEECHHCCHHHHHHHCCCCCCEEEEECCCCCHHEECCCCCCHHHHHHHEECCCC
CNITPHQTLYIFSDGIYEIPKTNNQLLGLEGFSHVLQQLHQIGSPTIETILDQVQICCKH
CCCCCCCEEEEEECCCEECCCCCCCEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
QRFTDDLSLMQVVFP
CCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]