Click here to switch to the map view.

The map label for this gene is cdsA [H]

Identifier: 158334334

GI number: 158334334

Start: 1123745

End: 1124617

Strand: Reverse

Name: cdsA [H]

Synonym: AM1_1155

Alternate gene names: 158334334

Gene position: 1124617-1123745 (Counterclockwise)

Preceding gene: 158334336

Following gene: 158334331

Centisome position: 17.29

GC content: 45.25

Gene sequence:

>873_bases
ATGCCTTGGGCTCGTATCATTAGTGGACTGATTGCCATCGTTCTAGCGTTGGGCATGATTTTATTGGGTGGATGGTACTT
TACCCTTGGTTTTTGCATCCTTGTCTATCTGGCTCAAGATGAGTATTTTGACCTGGTTCGGGCCAAAGGTAACCGGCCAG
CTGGCAAAACTACCATGATTGTTAGCCAGTTGCTGTTGATCACCGCCACCATTAACGGCATGCTGGCTGATGCGGTGTTA
CCCGTTGCGGGAACCTTCATCTGTTTTTATCTGTTATTTCAACCGAAACTGGCCACTATTTCCGATATTTCTAGTTCAAT
CTTGGGTCTCTTTTATGGGGGATACCTACCCAGTTTTTGGATTAGATTAAGAGCATTGGGCACGCCAGAAGCCAGCAATT
TACCCCTATGGGGATATTGGCCAGAACAATGGTCGAACATCAATTTGCTGCCTGTCGGATTAACGATTACCCTTCTTGCC
TTTGGTTGTATTTGGGCTGCAGATATTGGTGCTTATACATTTGGTCGGCTATTTGGTAAAACCCGATTATCAGATATTAG
CCCCAAAAAAACAGTAGAAGGAGCAGTATTCGGAGTTTTAGGTAGCCTGACCGTTGCTATCATTGGTGCAAATACCTTTA
TCTGGCCATTTTGGCTGTTTCTTGGAGCAGCCTTGGGGTTGTTGATTGGTGTTGCCAGTTTATTGGGAGACCTAACAGAA
TCCATGATGAAGCGAGATGCAGGAGTCAAAGACTCTGGGCAACTCATTCCTGGCCACGGCGGTATTTTAGATCGCGCGGA
TAGTTACGTATTTACGGCTCCCTTGGTTTACTATTTTGTCACCCTATTATTGCCACTCATAGAAGCCATATAA

Upstream 100 bases:

>100_bases
CTTTTTGCTATCCTCTATGCATCTTCTCTCAGCTTAACTAGCTGCGGAGAAAGACATCGGCGTAGGATAATACCCCTGAG
GGAAATAATAATCTACATAT

Downstream 100 bases:

>100_bases
TTCGGGAGCTTTTATCAGTCCATAGCCATAATCGAAGCCAGGTTAGTTTATTGATAGCTGGATAGAAGGCTTATGTAGGC
CATACCGGCTCTATTTTTGA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 290; Mature: 289

Protein sequence:

>290_residues
MPWARIISGLIAIVLALGMILLGGWYFTLGFCILVYLAQDEYFDLVRAKGNRPAGKTTMIVSQLLLITATINGMLADAVL
PVAGTFICFYLLFQPKLATISDISSSILGLFYGGYLPSFWIRLRALGTPEASNLPLWGYWPEQWSNINLLPVGLTITLLA
FGCIWAADIGAYTFGRLFGKTRLSDISPKKTVEGAVFGVLGSLTVAIIGANTFIWPFWLFLGAALGLLIGVASLLGDLTE
SMMKRDAGVKDSGQLIPGHGGILDRADSYVFTAPLVYYFVTLLLPLIEAI

Sequences:

>Translated_290_residues
MPWARIISGLIAIVLALGMILLGGWYFTLGFCILVYLAQDEYFDLVRAKGNRPAGKTTMIVSQLLLITATINGMLADAVL
PVAGTFICFYLLFQPKLATISDISSSILGLFYGGYLPSFWIRLRALGTPEASNLPLWGYWPEQWSNINLLPVGLTITLLA
FGCIWAADIGAYTFGRLFGKTRLSDISPKKTVEGAVFGVLGSLTVAIIGANTFIWPFWLFLGAALGLLIGVASLLGDLTE
SMMKRDAGVKDSGQLIPGHGGILDRADSYVFTAPLVYYFVTLLLPLIEAI
>Mature_289_residues
PWARIISGLIAIVLALGMILLGGWYFTLGFCILVYLAQDEYFDLVRAKGNRPAGKTTMIVSQLLLITATINGMLADAVLP
VAGTFICFYLLFQPKLATISDISSSILGLFYGGYLPSFWIRLRALGTPEASNLPLWGYWPEQWSNINLLPVGLTITLLAF
GCIWAADIGAYTFGRLFGKTRLSDISPKKTVEGAVFGVLGSLTVAIIGANTFIWPFWLFLGAALGLLIGVASLLGDLTES
MMKRDAGVKDSGQLIPGHGGILDRADSYVFTAPLVYYFVTLLLPLIEAI

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:
GO:0016020: Phosphatidate cytidylyltransferase
GO:0016740: Phosphatidate cytidylyltransferase
GO:0016772: Phosphatidate cytidylyltransferase
GO:0016779: Phosphatidate cytidylyltransferase

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=128, Percent_Identity=49.21875, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1787677, Length=116, Percent_Identity=42.2413793103448, Blast_Score=94, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 31413; Mature: 31281

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPWARIISGLIAIVLALGMILLGGWYFTLGFCILVYLAQDEYFDLVRAKGNRPAGKTTMI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VSQLLLITATINGMLADAVLPVAGTFICFYLLFQPKLATISDISSSILGLFYGGYLPSFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IRLRALGTPEASNLPLWGYWPEQWSNINLLPVGLTITLLAFGCIWAADIGAYTFGRLFGK
HHHHHCCCCCCCCCCEECCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLSDISPKKTVEGAVFGVLGSLTVAIIGANTFIWPFWLFLGAALGLLIGVASLLGDLTE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMMKRDAGVKDSGQLIPGHGGILDRADSYVFTAPLVYYFVTLLLPLIEAI
HHHHHCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PWARIISGLIAIVLALGMILLGGWYFTLGFCILVYLAQDEYFDLVRAKGNRPAGKTTMI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VSQLLLITATINGMLADAVLPVAGTFICFYLLFQPKLATISDISSSILGLFYGGYLPSFW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
IRLRALGTPEASNLPLWGYWPEQWSNINLLPVGLTITLLAFGCIWAADIGAYTFGRLFGK
HHHHHCCCCCCCCCCEECCCHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TRLSDISPKKTVEGAVFGVLGSLTVAIIGANTFIWPFWLFLGAALGLLIGVASLLGDLTE
HHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SMMKRDAGVKDSGQLIPGHGGILDRADSYVFTAPLVYYFVTLLLPLIEAI
HHHHHCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]