Click here to switch to the map view.

The map label for this gene is fabZ

Identifier: 158333777

GI number: 158333777

Start: 572352

End: 572822

Strand: Reverse

Name: fabZ

Synonym: AM1_0584

Alternate gene names: 158333777

Gene position: 572822-572352 (Counterclockwise)

Preceding gene: 158333778

Following gene: 158333775

Centisome position: 8.81

GC content: 50.74

Gene sequence:

>471_bases
ATGTCAAATCCCTCTGATGGCTCTACCGATCCCAAAACCACCTTTATGATTGAGGAGATTCAAGAGCTGCTGCCCCATCG
ATATCCCTTTCTTCTGGTAGATCGCATTATTGACTACAAAGAGTCTGAGCGGGCAGTGGGCATCAAGAACGTGACGATGA
ATGAAGAGTTCTTTCAGGGCCATTTCCCCGGTCGACCGCTGATGCCAGGGGTATTGATTGTGGAAGCCATGGCTCAAGTG
GGCGGAATTGTCCTGGCTCAACTTCCCGATATCCCTTCTGGCAAGTTATTTGTCTTCACAGGGATTGATAAAGTCCGAAT
TCGCCGCTCCGTTGTCCCAGGAGACCAGCTCGTGATTACCGCCGAATTCCTGTCTTTGAAGCGCAAGCGGTTTGCCATGA
TGTCCACGAAGGCTGAAGTGGACGGCAAACTGGCCTGTTCAGGAGAGCTGATGTTTGCCATGGTGGATTAA

Upstream 100 bases:

>100_bases
CATATAAAGCCAGTCACTCCCTCCACATTCGCTTTGCCAAACGCCTTCAGCAAGCCTTACTCGGCTGACTGCATTTTTTG
TTGAATCGTGATTGCTTATT

Downstream 100 bases:

>100_bases
TCGGCCCCAACCTCAGCCGTATCAACGCTTTGTTCAATGCTATCCATAGCCTGTAAATAGGCCGGATTGTCGGATTGGGG
GGTCGTTTCTTCTAACTCAG

Product: beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase

Number of amino acids: Translated: 156; Mature: 155

Protein sequence:

>156_residues
MSNPSDGSTDPKTTFMIEEIQELLPHRYPFLLVDRIIDYKESERAVGIKNVTMNEEFFQGHFPGRPLMPGVLIVEAMAQV
GGIVLAQLPDIPSGKLFVFTGIDKVRIRRSVVPGDQLVITAEFLSLKRKRFAMMSTKAEVDGKLACSGELMFAMVD

Sequences:

>Translated_156_residues
MSNPSDGSTDPKTTFMIEEIQELLPHRYPFLLVDRIIDYKESERAVGIKNVTMNEEFFQGHFPGRPLMPGVLIVEAMAQV
GGIVLAQLPDIPSGKLFVFTGIDKVRIRRSVVPGDQLVITAEFLSLKRKRFAMMSTKAEVDGKLACSGELMFAMVD
>Mature_155_residues
SNPSDGSTDPKTTFMIEEIQELLPHRYPFLLVDRIIDYKESERAVGIKNVTMNEEFFQGHFPGRPLMPGVLIVEAMAQVG
GIVLAQLPDIPSGKLFVFTGIDKVRIRRSVVPGDQLVITAEFLSLKRKRFAMMSTKAEVDGKLACSGELMFAMVD

Specific function: Involved in saturated fatty acids biosynthesis

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily

Homologues:

Organism=Escherichia coli, GI1786377, Length=146, Percent_Identity=48.6301369863014, Blast_Score=142, Evalue=9e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FABZ_ACAM1 (B0CD44)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001514949.1
- ProteinModelPortal:   B0CD44
- SMR:   B0CD44
- GeneID:   5679413
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_0584
- HOGENOM:   HBG433282
- OMA:   NVSANES
- BioCyc:   AMAR329726:AM1_0584-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00406
- InterPro:   IPR013114
- InterPro:   IPR010084
- TIGRFAMs:   TIGR01750

Pfam domain/function: PF07977 FabA

EC number: 4.2.1.-

Molecular weight: Translated: 17377; Mature: 17245

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: NA

Important sites: ACT_SITE 61-61

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
5.8 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNPSDGSTDPKTTFMIEEIQELLPHRYPFLLVDRIIDYKESERAVGIKNVTMNEEFFQG
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECHHHHCC
HFPGRPLMPGVLIVEAMAQVGGIVLAQLPDIPSGKLFVFTGIDKVRIRRSVVPGDQLVIT
CCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCHHHHHHHHCCCCCEEEEE
AEFLSLKRKRFAMMSTKAEVDGKLACSGELMFAMVD
HHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEC
>Mature Secondary Structure 
SNPSDGSTDPKTTFMIEEIQELLPHRYPFLLVDRIIDYKESERAVGIKNVTMNEEFFQG
CCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCEEEEEECHHHHCC
HFPGRPLMPGVLIVEAMAQVGGIVLAQLPDIPSGKLFVFTGIDKVRIRRSVVPGDQLVIT
CCCCCCCCCHHHHHHHHHHHCCEEEEECCCCCCCCEEEEECCHHHHHHHHCCCCCEEEEE
AEFLSLKRKRFAMMSTKAEVDGKLACSGELMFAMVD
HHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA