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The map label for this gene is lpxA [H]

Identifier: 158333775

GI number: 158333775

Start: 569906

End: 570721

Strand: Reverse

Name: lpxA [H]

Synonym: AM1_0583

Alternate gene names: 158333775

Gene position: 570721-569906 (Counterclockwise)

Preceding gene: 158333777

Following gene: 158333774

Centisome position: 8.78

GC content: 53.06

Gene sequence:

>816_bases
ATGACCGACTTGATTCACCCCACCGCTGTGATTCATCCCCAAGCAACCTTGCATCAAACGGTTCAAATTGGAGCCTATGC
GGTGATTGGAAAACAGGTCAAACTAGGCCCCGGAACCCAGGTCGGACATCACGCTGTAATCGAAGGCTGGACTGAGATTG
GGGCCGACAATCATATATTTCCGGGAGTGGTGATTGGCATGGAACCTCAGGATCGCAATTTTCGCGGGGAACAGAGCGGT
GTCAAGATTTGCGATCGCAACCAGATACGCGAATATGTCACCATCCATCGAGCCAGTGGAGACCAACAGTTCACCACCAT
TGGCAGCGATAATCTATTGATGGCCAATGTGCATATTGGCCATAACTGTCATATTGCCGATCGGGTGGTGATAGCCAATT
CCGTCGCCCTAAGTGGCCATGTGCAGGTGGAATCCCAAGCCAACATTAGTGGGGTACTCGGTATTCATCAGTTTGTCCAT
GTGGGTCAGCTGGCCATGATTGGGGGCATGAGCCGCATTACCCGAGATGTCCCTCCCTTGATGCTCGTAGAGGGTAATCC
TGCCCATGTCCGGGCCTTAAACCAAGTAGGATTGCAGCGTCATGGAGTCTACGACCTCCTGCAGGGGGAGATGAGAGGCC
TCCTTAAGCAAGCCTTTCGGTATCTGTATCGGTCGAACCTCCAATTAGAAGTGGCCCTTGATCAAGTCGAATCTTTATCG
GAGCATCCCCTGATTCAACATTTGTGCCAGTTTATGCGGGCAGCCCAAACCAGGCGCGGCCTCACCCCTGGGCGTCAGCG
CTGGGCTTCGGTCTAA

Upstream 100 bases:

>100_bases
CGCATTAATTTCTACACTCAATACAATCGGAAGACGAGGAGTTTTGGCCGTTTATCTAAAATGCTACCCTCAGATAGCCA
TTGTAAAACGCAGACCCTGA

Downstream 100 bases:

>100_bases
GGCACGATGGATCGGCCCTACCGAATTTTTATCAGTACCGGCGAGGTCTCTGGCGATCTCCAGGGCAGTTTACTGATTCC
TGCCTTGATGGCAGAAGCCC

Product: acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase

Products: NA

Alternate protein names: UDP-N-acetylglucosamine acyltransferase [H]

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MTDLIHPTAVIHPQATLHQTVQIGAYAVIGKQVKLGPGTQVGHHAVIEGWTEIGADNHIFPGVVIGMEPQDRNFRGEQSG
VKICDRNQIREYVTIHRASGDQQFTTIGSDNLLMANVHIGHNCHIADRVVIANSVALSGHVQVESQANISGVLGIHQFVH
VGQLAMIGGMSRITRDVPPLMLVEGNPAHVRALNQVGLQRHGVYDLLQGEMRGLLKQAFRYLYRSNLQLEVALDQVESLS
EHPLIQHLCQFMRAAQTRRGLTPGRQRWASV

Sequences:

>Translated_271_residues
MTDLIHPTAVIHPQATLHQTVQIGAYAVIGKQVKLGPGTQVGHHAVIEGWTEIGADNHIFPGVVIGMEPQDRNFRGEQSG
VKICDRNQIREYVTIHRASGDQQFTTIGSDNLLMANVHIGHNCHIADRVVIANSVALSGHVQVESQANISGVLGIHQFVH
VGQLAMIGGMSRITRDVPPLMLVEGNPAHVRALNQVGLQRHGVYDLLQGEMRGLLKQAFRYLYRSNLQLEVALDQVESLS
EHPLIQHLCQFMRAAQTRRGLTPGRQRWASV
>Mature_270_residues
TDLIHPTAVIHPQATLHQTVQIGAYAVIGKQVKLGPGTQVGHHAVIEGWTEIGADNHIFPGVVIGMEPQDRNFRGEQSGV
KICDRNQIREYVTIHRASGDQQFTTIGSDNLLMANVHIGHNCHIADRVVIANSVALSGHVQVESQANISGVLGIHQFVHV
GQLAMIGGMSRITRDVPPLMLVEGNPAHVRALNQVGLQRHGVYDLLQGEMRGLLKQAFRYLYRSNLQLEVALDQVESLSE
HPLIQHLCQFMRAAQTRRGLTPGRQRWASV

Specific function: Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG1043

COG function: function code M; Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family. LpxA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786378, Length=260, Percent_Identity=37.6923076923077, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010137
- InterPro:   IPR011004 [H]

Pfam domain/function: NA

EC number: =2.3.1.129 [H]

Molecular weight: Translated: 29853; Mature: 29722

Theoretical pI: Translated: 8.19; Mature: 8.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLIHPTAVIHPQATLHQTVQIGAYAVIGKQVKLGPGTQVGHHAVIEGWTEIGADNHIF
CCCCCCCCEEECCCHHHHHHHHHCEEEEECCEEECCCCCCCCCHHHHHHHHHHCCCCCCC
PGVVIGMEPQDRNFRGEQSGVKICDRNQIREYVTIHRASGDQQFTTIGSDNLLMANVHIG
CEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHEEEECCCCCEEEEECCCCEEEEEEEEC
HNCHIADRVVIANSVALSGHVQVESQANISGVLGIHQFVHVGQLAMIGGMSRITRDVPPL
CCCCHHCEEEEECCEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
MLVEGNPAHVRALNQVGLQRHGVYDLLQGEMRGLLKQAFRYLYRSNLQLEVALDQVESLS
EEEECCCHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHC
EHPLIQHLCQFMRAAQTRRGLTPGRQRWASV
CCHHHHHHHHHHHHHHHHCCCCCCHHHHCCC
>Mature Secondary Structure 
TDLIHPTAVIHPQATLHQTVQIGAYAVIGKQVKLGPGTQVGHHAVIEGWTEIGADNHIF
CCCCCCCEEECCCHHHHHHHHHCEEEEECCEEECCCCCCCCCHHHHHHHHHHCCCCCCC
PGVVIGMEPQDRNFRGEQSGVKICDRNQIREYVTIHRASGDQQFTTIGSDNLLMANVHIG
CEEEEECCCCCCCCCCCCCCCEEECHHHHHHHHEEEECCCCCEEEEECCCCEEEEEEEEC
HNCHIADRVVIANSVALSGHVQVESQANISGVLGIHQFVHVGQLAMIGGMSRITRDVPPL
CCCCHHCEEEEECCEEEECEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCE
MLVEGNPAHVRALNQVGLQRHGVYDLLQGEMRGLLKQAFRYLYRSNLQLEVALDQVESLS
EEEECCCHHHHHHHHHCHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHC
EHPLIQHLCQFMRAAQTRRGLTPGRQRWASV
CCHHHHHHHHHHHHHHHHCCCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA