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The map label for this gene is yciR [C]

Identifier: 158333247

GI number: 158333247

Start: 14131

End: 16395

Strand: Reverse

Name: yciR [C]

Synonym: AM1_0016

Alternate gene names: 158333247

Gene position: 16395-14131 (Counterclockwise)

Preceding gene: 158333248

Following gene: 158333246

Centisome position: 0.25

GC content: 45.17

Gene sequence:

>2265_bases
GTGAGCAAAGGCACGATCATTTGCATTGATGATGACCGATTGATTTTGAATACTCTGAGAGATCAATTGCAGCGAATTAT
CGACGATAGTTATGAAATTGAGGTGGCAGAAAGCGGTGGTGAGGCCCTCGAACTATTTACAGAATTAGAGGCGGATCAAA
TTCCGATCCCCTTGGTTATTTGTGATCAGAATTTACCGGATATGGGGGGGGATTCTCTTCTCAGTTATTTACAGATTCAG
TACCCCAAAACCCGAAAAATTCTGTTAACTGGGGAGGCGAATTTAGATGCGGTCATTAACGCGGTTAATTCTGCCAATTT
ATATCGTTACATCGCTAAACCTTGGGATGAAACTGATTTAGGTTTAACGGTAAAGGCGGCTTTAAGGAGTCACCTACAAG
ATGAACAGCTAATTGGCCAGAATAGAACCCTGCGAGCGATGAATGCTCAATTACAGGGGGAAATCGATGAACGTCAGCTC
GTACAGCAGAAGCTGCAGGAGAGTGAAACCCGTTTAGAAAGCATTCTCAATTCATTGGATGATGTGGTGTGGTCAGCAGC
CGTTGAAGAGTTTCAACTGTTGTATTTGAACCCAGCAGCAGAAGCGGTTCATGGCTATCCGGTGTCGTCATTCCTCAGTA
ATCCTGATTTATGGCTAGAGGTGGTTCATCCTGCGGATCGTCATCAAATGATCCATTTCTTTGATCAATTGCTCGTTGCC
GGTTCCCTTAATATTGAATATCGAATATTGCGGCCCGATGGAGAAATTAGGTGGCTGAAAAATCGAGGCCATGTGATCAC
GGGTGATCAAGGACGTCCCCACCGCCTAGATGGAATTATTTACGATATTACGGAGCAAAAACGGGCTCAAGCTCAATTAA
TCCACGATGCCTTTCATGATGAATTAACGGGACTACCAAACCGTAATTTGATGATGGAGCGCATTTCTCAGTCCTTGAAG
CGCCAGCATCGCACGTCCGATTATCAATTTGCGCTGCTGTTTATTGATCTGGACCGATTTAAGATTATCAACGACAGTTT
GGGACATATTGTCGGTGACCAATTGCTAGTTGCGATCGCACATCTGTTAGAAAACTGTGTGCGCACCTCTGATACCGTGG
CCCGTCTTGGGGGAGATGAATTTACCATTCTCCTGGATGGTATTCAAGGCATAGAGGATGCGATCCATGTGGCAGAACGC
ATCCTGGAAACCTTAAAATCGCCCTTTCAGGTGGGAGAACATAGTGTCTTTACGGGATCCAGTATCGGAATCGCTTACAA
CTCGGTGCAGTATGACGATCCAACCTTATTATTGCGGGATGCAGATATTGCCATGTATCGTGCTAAATCCTTAGGGAAAG
GTTGTTTTGTAGTATTCAGCCCAGAGATGCATGCCCAGACCCTTAGCCTGCTCAAACTTGAACGAGATCTGCGGTCTGCG
GTTGATCGACAAGAATTTGTGCTGTATTACCAGCCGATCATTGACCTGCAGTCAGGAGACCTTACGGATGTTGAGGTCTT
GGTTAGGTGGCAACATCCGGATCGGGGATTAGTGATGCCATCGGAATTTATCCCCTTAGCAGAAGAGACGGGGCTAATCG
TAGAAATTGGTCAGTGGGTACTTCAGGAAGCCTGCCAGACTCTACGAGATTATCAACAACAGTTTGCCTCTGCAACGGAG
TTGAAATTTAGCGTCAATTTATCCAGTGAACAACTGCAAGATCCTAACTTTATCCAAACTGTGGATCGGGTTTTATCTCA
GTCCGGGTTAGACGGACGATATTTAAAGCTTGAACTCACTGAAAGTATGCTGATGTCCCATGAAGAGAAGCATATAAAGA
CGCTGCAGCAACTGCGCGATCGCAGCATAACCATCAGCCTGGATGACTTTGGGACGGGGTATTCGTCTTTGAGCTACCTT
TACCGATTTCCCTTAGATACCCTCAAGATTGATCAATCTTTTGTGAGTCGGATGATCTCCGAACCGAAAGATGCTGAGAT
TGTGAATACCATTATTTCTCTGGCCCGCACCTTAAATATGGATGTAATTGCCGAAGGAATTGAAACAGAAGAAGAAGTTT
TACACTTAAAGAAATTGGGTTGCGAACGGGGACAAGGATATTGGTTCTCTCCACCCATGAGTCAGGAGAAGTTAGAAGAA
CATCTTCAGGCTGGACCTCAATGGTTTGTTCAACAACAGCCCATGAACCCTAATTTTTCCTTTCTAGCACCATCTACGTC
GCCCATTGTGGATGTGCAGAATTAA

Upstream 100 bases:

>100_bases
GAGCTAATCAGTTGAAAATGTGCTTGAATATCAGGTTAATCCTCATTGTATTTGAACGGAATGTGCCCAAAGTGACGACA
GCGACAATGGTGGAGCAACG

Downstream 100 bases:

>100_bases
ATTCCTGTAAAGACTTTCTCCACTCTGGGGGACCTAAAGAGAGAATAAGAATTTAAGAGCGAGAGATGGGCAAGGAATAG
AGGTAATCCCGCATTTTGAT

Product: PAS/PAC sensor-containing diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 754; Mature: 753

Protein sequence:

>754_residues
MSKGTIICIDDDRLILNTLRDQLQRIIDDSYEIEVAESGGEALELFTELEADQIPIPLVICDQNLPDMGGDSLLSYLQIQ
YPKTRKILLTGEANLDAVINAVNSANLYRYIAKPWDETDLGLTVKAALRSHLQDEQLIGQNRTLRAMNAQLQGEIDERQL
VQQKLQESETRLESILNSLDDVVWSAAVEEFQLLYLNPAAEAVHGYPVSSFLSNPDLWLEVVHPADRHQMIHFFDQLLVA
GSLNIEYRILRPDGEIRWLKNRGHVITGDQGRPHRLDGIIYDITEQKRAQAQLIHDAFHDELTGLPNRNLMMERISQSLK
RQHRTSDYQFALLFIDLDRFKIINDSLGHIVGDQLLVAIAHLLENCVRTSDTVARLGGDEFTILLDGIQGIEDAIHVAER
ILETLKSPFQVGEHSVFTGSSIGIAYNSVQYDDPTLLLRDADIAMYRAKSLGKGCFVVFSPEMHAQTLSLLKLERDLRSA
VDRQEFVLYYQPIIDLQSGDLTDVEVLVRWQHPDRGLVMPSEFIPLAEETGLIVEIGQWVLQEACQTLRDYQQQFASATE
LKFSVNLSSEQLQDPNFIQTVDRVLSQSGLDGRYLKLELTESMLMSHEEKHIKTLQQLRDRSITISLDDFGTGYSSLSYL
YRFPLDTLKIDQSFVSRMISEPKDAEIVNTIISLARTLNMDVIAEGIETEEEVLHLKKLGCERGQGYWFSPPMSQEKLEE
HLQAGPQWFVQQQPMNPNFSFLAPSTSPIVDVQN

Sequences:

>Translated_754_residues
MSKGTIICIDDDRLILNTLRDQLQRIIDDSYEIEVAESGGEALELFTELEADQIPIPLVICDQNLPDMGGDSLLSYLQIQ
YPKTRKILLTGEANLDAVINAVNSANLYRYIAKPWDETDLGLTVKAALRSHLQDEQLIGQNRTLRAMNAQLQGEIDERQL
VQQKLQESETRLESILNSLDDVVWSAAVEEFQLLYLNPAAEAVHGYPVSSFLSNPDLWLEVVHPADRHQMIHFFDQLLVA
GSLNIEYRILRPDGEIRWLKNRGHVITGDQGRPHRLDGIIYDITEQKRAQAQLIHDAFHDELTGLPNRNLMMERISQSLK
RQHRTSDYQFALLFIDLDRFKIINDSLGHIVGDQLLVAIAHLLENCVRTSDTVARLGGDEFTILLDGIQGIEDAIHVAER
ILETLKSPFQVGEHSVFTGSSIGIAYNSVQYDDPTLLLRDADIAMYRAKSLGKGCFVVFSPEMHAQTLSLLKLERDLRSA
VDRQEFVLYYQPIIDLQSGDLTDVEVLVRWQHPDRGLVMPSEFIPLAEETGLIVEIGQWVLQEACQTLRDYQQQFASATE
LKFSVNLSSEQLQDPNFIQTVDRVLSQSGLDGRYLKLELTESMLMSHEEKHIKTLQQLRDRSITISLDDFGTGYSSLSYL
YRFPLDTLKIDQSFVSRMISEPKDAEIVNTIISLARTLNMDVIAEGIETEEEVLHLKKLGCERGQGYWFSPPMSQEKLEE
HLQAGPQWFVQQQPMNPNFSFLAPSTSPIVDVQN
>Mature_753_residues
SKGTIICIDDDRLILNTLRDQLQRIIDDSYEIEVAESGGEALELFTELEADQIPIPLVICDQNLPDMGGDSLLSYLQIQY
PKTRKILLTGEANLDAVINAVNSANLYRYIAKPWDETDLGLTVKAALRSHLQDEQLIGQNRTLRAMNAQLQGEIDERQLV
QQKLQESETRLESILNSLDDVVWSAAVEEFQLLYLNPAAEAVHGYPVSSFLSNPDLWLEVVHPADRHQMIHFFDQLLVAG
SLNIEYRILRPDGEIRWLKNRGHVITGDQGRPHRLDGIIYDITEQKRAQAQLIHDAFHDELTGLPNRNLMMERISQSLKR
QHRTSDYQFALLFIDLDRFKIINDSLGHIVGDQLLVAIAHLLENCVRTSDTVARLGGDEFTILLDGIQGIEDAIHVAERI
LETLKSPFQVGEHSVFTGSSIGIAYNSVQYDDPTLLLRDADIAMYRAKSLGKGCFVVFSPEMHAQTLSLLKLERDLRSAV
DRQEFVLYYQPIIDLQSGDLTDVEVLVRWQHPDRGLVMPSEFIPLAEETGLIVEIGQWVLQEACQTLRDYQQQFASATEL
KFSVNLSSEQLQDPNFIQTVDRVLSQSGLDGRYLKLELTESMLMSHEEKHIKTLQQLRDRSITISLDDFGTGYSSLSYLY
RFPLDTLKIDQSFVSRMISEPKDAEIVNTIISLARTLNMDVIAEGIETEEEVLHLKKLGCERGQGYWFSPPMSQEKLEEH
LQAGPQWFVQQQPMNPNFSFLAPSTSPIVDVQN

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=439, Percent_Identity=39.1799544419134, Blast_Score=318, Evalue=8e-88,
Organism=Escherichia coli, GI87081921, Length=451, Percent_Identity=32.5942350332594, Blast_Score=241, Evalue=1e-64,
Organism=Escherichia coli, GI226510982, Length=430, Percent_Identity=30.6976744186047, Blast_Score=201, Evalue=2e-52,
Organism=Escherichia coli, GI87081845, Length=348, Percent_Identity=28.735632183908, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1787055, Length=241, Percent_Identity=34.0248962655602, Blast_Score=162, Evalue=7e-41,
Organism=Escherichia coli, GI1788502, Length=280, Percent_Identity=30.7142857142857, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1786507, Length=248, Percent_Identity=34.6774193548387, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1790496, Length=258, Percent_Identity=32.5581395348837, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI87081980, Length=264, Percent_Identity=30.3030303030303, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081743, Length=250, Percent_Identity=33.2, Blast_Score=132, Evalue=8e-32,
Organism=Escherichia coli, GI1788849, Length=443, Percent_Identity=26.1851015801354, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI1788381, Length=553, Percent_Identity=27.124773960217, Blast_Score=120, Evalue=4e-28,
Organism=Escherichia coli, GI87082096, Length=248, Percent_Identity=31.4516129032258, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI87081881, Length=175, Percent_Identity=40.5714285714286, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI87081977, Length=185, Percent_Identity=33.5135135135135, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1786584, Length=157, Percent_Identity=35.031847133758, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI87082007, Length=167, Percent_Identity=34.1317365269461, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788956, Length=163, Percent_Identity=34.9693251533742, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1787262, Length=169, Percent_Identity=31.9526627218935, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI145693134, Length=164, Percent_Identity=35.9756097560976, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1787802, Length=180, Percent_Identity=30, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1787816, Length=163, Percent_Identity=30.0613496932515, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1788085, Length=201, Percent_Identity=28.3582089552239, Blast_Score=73, Evalue=7e-14,
Organism=Escherichia coli, GI1787056, Length=182, Percent_Identity=29.1208791208791, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787410, Length=149, Percent_Identity=29.5302013422819, Blast_Score=66, Evalue=9e-12,
Organism=Escherichia coli, GI87081974, Length=86, Percent_Identity=38.3720930232558, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 85583; Mature: 85452

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKGTIICIDDDRLILNTLRDQLQRIIDDSYEIEVAESGGEALELFTELEADQIPIPLVI
CCCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCEEEEE
CDQNLPDMGGDSLLSYLQIQYPKTRKILLTGEANLDAVINAVNSANLYRYIAKPWDETDL
ECCCCCCCCHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHCCHHHHHHHCCCCCCCCC
GLTVKAALRSHLQDEQLIGQNRTLRAMNAQLQGEIDERQLVQQKLQESETRLESILNSLD
CEEHHHHHHHCCCHHHHHCCCCEEHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DVVWSAAVEEFQLLYLNPAAEAVHGYPVSSFLSNPDLWLEVVHPADRHQMIHFFDQLLVA
HHHHHHHHHHEEEEEECCHHHHHCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
GSLNIEYRILRPDGEIRWLKNRGHVITGDQGRPHRLDGIIYDITEQKRAQAQLIHDAFHD
CCCCEEEEEECCCCCEEEEECCCCEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH
ELTGLPNRNLMMERISQSLKRQHRTSDYQFALLFIDLDRFKIINDSLGHIVGDQLLVAIA
HHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
HLLENCVRTSDTVARLGGDEFTILLDGIQGIEDAIHVAERILETLKSPFQVGEHSVFTGS
HHHHHHHHCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCHHHCCCCCEECCC
SIGIAYNSVQYDDPTLLLRDADIAMYRAKSLGKGCFVVFSPEMHAQTLSLLKLERDLRSA
CCCEEECCEECCCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
VDRQEFVLYYQPIIDLQSGDLTDVEVLVRWQHPDRGLVMPSEFIPLAEETGLIVEIGQWV
CCHHHEEEEEECEEECCCCCCCCEEEEEEEECCCCCCCCCHHCCCCCCCCCCCHHHHHHH
LQEACQTLRDYQQQFASATELKFSVNLSSEQLQDPNFIQTVDRVLSQSGLDGRYLKLELT
HHHHHHHHHHHHHHHCCHHEEEEEEECCHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEEH
ESMLMSHEEKHIKTLQQLRDRSITISLDDFGTGYSSLSYLYRFPLDTLKIDQSFVSRMIS
HHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
EPKDAEIVNTIISLARTLNMDVIAEGIETEEEVLHLKKLGCERGQGYWFSPPMSQEKLEE
CCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHH
HLQAGPQWFVQQQPMNPNFSFLAPSTSPIVDVQN
HHHCCCCEEEECCCCCCCCEEECCCCCCCEECCC
>Mature Secondary Structure 
SKGTIICIDDDRLILNTLRDQLQRIIDDSYEIEVAESGGEALELFTELEADQIPIPLVI
CCCEEEEECCCHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHCCCCCCCEEEEE
CDQNLPDMGGDSLLSYLQIQYPKTRKILLTGEANLDAVINAVNSANLYRYIAKPWDETDL
ECCCCCCCCHHHHHHHHHEECCCCEEEEEECCCCHHHHHHHHCCHHHHHHHCCCCCCCCC
GLTVKAALRSHLQDEQLIGQNRTLRAMNAQLQGEIDERQLVQQKLQESETRLESILNSLD
CEEHHHHHHHCCCHHHHHCCCCEEHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
DVVWSAAVEEFQLLYLNPAAEAVHGYPVSSFLSNPDLWLEVVHPADRHQMIHFFDQLLVA
HHHHHHHHHHEEEEEECCHHHHHCCCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHH
GSLNIEYRILRPDGEIRWLKNRGHVITGDQGRPHRLDGIIYDITEQKRAQAQLIHDAFHD
CCCCEEEEEECCCCCEEEEECCCCEEECCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHH
ELTGLPNRNLMMERISQSLKRQHRTSDYQFALLFIDLDRFKIINDSLGHIVGDQLLVAIA
HHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHH
HLLENCVRTSDTVARLGGDEFTILLDGIQGIEDAIHVAERILETLKSPFQVGEHSVFTGS
HHHHHHHHCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCHHHCCCCCEECCC
SIGIAYNSVQYDDPTLLLRDADIAMYRAKSLGKGCFVVFSPEMHAQTLSLLKLERDLRSA
CCCEEECCEECCCCEEEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHH
VDRQEFVLYYQPIIDLQSGDLTDVEVLVRWQHPDRGLVMPSEFIPLAEETGLIVEIGQWV
CCHHHEEEEEECEEECCCCCCCCEEEEEEEECCCCCCCCCHHCCCCCCCCCCCHHHHHHH
LQEACQTLRDYQQQFASATELKFSVNLSSEQLQDPNFIQTVDRVLSQSGLDGRYLKLELT
HHHHHHHHHHHHHHHCCHHEEEEEEECCHHHCCCCHHHHHHHHHHHHCCCCCEEEEEEEH
ESMLMSHEEKHIKTLQQLRDRSITISLDDFGTGYSSLSYLYRFPLDTLKIDQSFVSRMIS
HHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHC
EPKDAEIVNTIISLARTLNMDVIAEGIETEEEVLHLKKLGCERGQGYWFSPPMSQEKLEE
CCCCHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCCCCCCCEEECCCCCHHHHHH
HLQAGPQWFVQQQPMNPNFSFLAPSTSPIVDVQN
HHHCCCCEEEECCCCCCCCEEECCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]