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The map label for this gene is qacA [H]

Identifier: 158318843

GI number: 158318843

Start: 8693594

End: 8695147

Strand: Reverse

Name: qacA [H]

Synonym: Franean1_7124

Alternate gene names: 158318843

Gene position: 8695147-8693594 (Counterclockwise)

Preceding gene: 158318848

Following gene: 158318842

Centisome position: 96.81

GC content: 70.21

Gene sequence:

>1554_bases
ATGCAGAGGTCGGGGTCGCAGCGGTGGTGGGCGCTGGGGGCGGTCAACCTGAGCGTGCTCGCCGTCAGCCTGGACGGCAC
GGTCCTGTCGGTGGCTCAACCGACGCTGTCGACGGCGCTCGGCGCCTCGCAGTCCGATCTGGTGTGGTTCTCCGCTGGTT
ATCTGCTCGTGCTGGCCGCGGCCGTGCTGCCCGTCGGCTTGGCAGGTGACCGTTTCGGACGCCGCAGAGTCCTGCTCGCG
TCGCTGGCCATATTCGGGCTGGGGTCCGTGCTCTGCGCCTACGCGGGGTCGCCGGGGGTGTTCCTTGCGGGACGGTTGTT
CCAGGGTCTGGCCGGCGCCGGTATCACCGTGATGGCACTGTCCGCCCTGGTCGTCCTGTTCGACGAGCAGGAACGTCCGA
GAGCGGTGGGGATCTACCAGGCGGCGAACTTCGTAGCCCTGCCGCTCGGCCCGATTCTCGGTGGCTGGATGCTGTCGCGG
TTCTGGTGGGGCTGGGTCTTCCTGCTCAACGTGCCGGTCGTCGTCCTCGCGGCAGTGATCGGCTTCGTCCTGATCCCGGA
GTCGCGATCGACGCAACGCCCTGGTCTGGACCCGGTCGGCACCGCGGCGTCAGCGTCTGGACTGGCAATGGTGATCTACG
GTTTGGTGCGCGCGGGGGAGCGCGGCTGGGGCAGCCTGGACGCGCTGCTGTCGATGGCCGCCGGAGCCGCGGTGGTGGTC
GGGTTCGTCTGGTGGGAGCGCAGGCTTGGTCGGCGGCCGACCGGCCGGCCGCTGGTCAACCCGCAGCTCCTGCGGCCGGG
GCTGTTCCTGTGGGGATCGGCACTCGCCGCGGTCGCGGGTCTGGCGATGATCGGAGTGCTGTTCACGATGCCTCAGTACT
TCCAGGGAGTGCGGGGTACCGGCACCCTGGGCAGCGGCCTGCGGCTACTGCCCCTCATCGGCGGCATGGTCGTCGGCGCC
GGGCTCGCCAGCCGGCTCGCACCGGCGATCACCACGCGACTGGCGGCAGCGCTGGGGTTCATACTCCTGGCGGGCGGTCT
CATCGTGGGAGCCACCACGACGTCCACCTCTGGCACGGTATTCACCGCAGGGTGGACGGCGCTCGTCGGCGCGGGAACAG
GACTGGCCCTGTCGGTGGCGACCGCGGCGGCACTGGCCGGGTTGTCGGCCGAACGCAGCGGCACTGAGTCCGCTGTCGTG
CAGGCGTTCAACAAGACAAGCGGCCCACTTGGTACAGCGATCACCGGCAGTGTCCTCGTTGCGGTCTACCACGCCCGACT
CGACAGCGTCGGGCTCCCGGAGACGGTGGCCGCAACGGCACGCAGGAGCCTCTACGGCGGCACGGCCACCGCACAGGCAG
CCGGGGGACCAGGGCTGGAGCAGGCGGTCCGCGCGGCGTTCGTCGACGGGATGAGCGCCGCGTTCCTGGTATCCGCCGTG
ATCGCCATACTTGGAGCCTGCGTGGCTCTGGCAGTCCTTCCCCGGGGCCGATCGCGTAGAACGGAAGCCGGTCAGCCGAC
CGAGGAAGGGACCGTCGATGCCGTCGAGCACTGA

Upstream 100 bases:

>100_bases
CGAGGCCCCACGCTCCTCGAGCCCATCGTAGAGCACGAGCCGTCCGAATGTGGGTGTTACCTTCTTTTGAAGGTAGCACC
CACAAGGAGGAGGCTGTCGG

Downstream 100 bases:

>100_bases
CCGGGCAGCGCCTGGCCTGCGAGAACGCAAGAAGGCCCGGACCAGGGCCGCAATCCAGACCCACGCCCTGCGACTGTTTC
GCGAACAGGGCTACAACGCG

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MQRSGSQRWWALGAVNLSVLAVSLDGTVLSVAQPTLSTALGASQSDLVWFSAGYLLVLAAAVLPVGLAGDRFGRRRVLLA
SLAIFGLGSVLCAYAGSPGVFLAGRLFQGLAGAGITVMALSALVVLFDEQERPRAVGIYQAANFVALPLGPILGGWMLSR
FWWGWVFLLNVPVVVLAAVIGFVLIPESRSTQRPGLDPVGTAASASGLAMVIYGLVRAGERGWGSLDALLSMAAGAAVVV
GFVWWERRLGRRPTGRPLVNPQLLRPGLFLWGSALAAVAGLAMIGVLFTMPQYFQGVRGTGTLGSGLRLLPLIGGMVVGA
GLASRLAPAITTRLAAALGFILLAGGLIVGATTTSTSGTVFTAGWTALVGAGTGLALSVATAAALAGLSAERSGTESAVV
QAFNKTSGPLGTAITGSVLVAVYHARLDSVGLPETVAATARRSLYGGTATAQAAGGPGLEQAVRAAFVDGMSAAFLVSAV
IAILGACVALAVLPRGRSRRTEAGQPTEEGTVDAVEH

Sequences:

>Translated_517_residues
MQRSGSQRWWALGAVNLSVLAVSLDGTVLSVAQPTLSTALGASQSDLVWFSAGYLLVLAAAVLPVGLAGDRFGRRRVLLA
SLAIFGLGSVLCAYAGSPGVFLAGRLFQGLAGAGITVMALSALVVLFDEQERPRAVGIYQAANFVALPLGPILGGWMLSR
FWWGWVFLLNVPVVVLAAVIGFVLIPESRSTQRPGLDPVGTAASASGLAMVIYGLVRAGERGWGSLDALLSMAAGAAVVV
GFVWWERRLGRRPTGRPLVNPQLLRPGLFLWGSALAAVAGLAMIGVLFTMPQYFQGVRGTGTLGSGLRLLPLIGGMVVGA
GLASRLAPAITTRLAAALGFILLAGGLIVGATTTSTSGTVFTAGWTALVGAGTGLALSVATAAALAGLSAERSGTESAVV
QAFNKTSGPLGTAITGSVLVAVYHARLDSVGLPETVAATARRSLYGGTATAQAAGGPGLEQAVRAAFVDGMSAAFLVSAV
IAILGACVALAVLPRGRSRRTEAGQPTEEGTVDAVEH
>Mature_517_residues
MQRSGSQRWWALGAVNLSVLAVSLDGTVLSVAQPTLSTALGASQSDLVWFSAGYLLVLAAAVLPVGLAGDRFGRRRVLLA
SLAIFGLGSVLCAYAGSPGVFLAGRLFQGLAGAGITVMALSALVVLFDEQERPRAVGIYQAANFVALPLGPILGGWMLSR
FWWGWVFLLNVPVVVLAAVIGFVLIPESRSTQRPGLDPVGTAASASGLAMVIYGLVRAGERGWGSLDALLSMAAGAAVVV
GFVWWERRLGRRPTGRPLVNPQLLRPGLFLWGSALAAVAGLAMIGVLFTMPQYFQGVRGTGTLGSGLRLLPLIGGMVVGA
GLASRLAPAITTRLAAALGFILLAGGLIVGATTTSTSGTVFTAGWTALVGAGTGLALSVATAAALAGLSAERSGTESAVV
QAFNKTSGPLGTAITGSVLVAVYHARLDSVGLPETVAATARRSLYGGTATAQAAGGPGLEQAVRAAFVDGMSAAFLVSAV
IAILGACVALAVLPRGRSRRTEAGQPTEEGTVDAVEH

Specific function: Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=394, Percent_Identity=27.4111675126904, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1789042, Length=478, Percent_Identity=25.3138075313808, Blast_Score=112, Evalue=5e-26,
Organism=Escherichia coli, GI1788710, Length=440, Percent_Identity=24.7727272727273, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1790195, Length=414, Percent_Identity=24.8792270531401, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788392, Length=315, Percent_Identity=29.2063492063492, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790146, Length=137, Percent_Identity=32.1167883211679, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322958, Length=529, Percent_Identity=22.8733459357278, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319770, Length=488, Percent_Identity=20.6967213114754, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 52493; Mature: 52493

Theoretical pI: Translated: 11.24; Mature: 11.24

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRSGSQRWWALGAVNLSVLAVSLDGTVLSVAQPTLSTALGASQSDLVWFSAGYLLVLAA
CCCCCCCCEEEEEECEEEEEEEEECCCEEECCCHHHHHHHCCCCCCEEEEHHHHHHHHHH
AVLPVGLAGDRFGRRRVLLASLAIFGLGSVLCAYAGSPGVFLAGRLFQGLAGAGITVMAL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHH
SALVVLFDEQERPRAVGIYQAANFVALPLGPILGGWMLSRFWWGWVFLLNVPVVVLAAVI
HHHHHHCCCCCCCCEEEEEHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVLIPESRSTQRPGLDPVGTAASASGLAMVIYGLVRAGERGWGSLDALLSMAAGAAVVV
HHEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHH
GFVWWERRLGRRPTGRPLVNPQLLRPGLFLWGSALAAVAGLAMIGVLFTMPQYFQGVRGT
HHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GTLGSGLRLLPLIGGMVVGAGLASRLAPAITTRLAAALGFILLAGGLIVGATTTSTSGTV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEE
FTAGWTALVGAGTGLALSVATAAALAGLSAERSGTESAVVQAFNKTSGPLGTAITGSVLV
EECCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
AVYHARLDSVGLPETVAATARRSLYGGTATAQAAGGPGLEQAVRAAFVDGMSAAFLVSAV
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
IAILGACVALAVLPRGRSRRTEAGQPTEEGTVDAVEH
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQRSGSQRWWALGAVNLSVLAVSLDGTVLSVAQPTLSTALGASQSDLVWFSAGYLLVLAA
CCCCCCCCEEEEEECEEEEEEEEECCCEEECCCHHHHHHHCCCCCCEEEEHHHHHHHHHH
AVLPVGLAGDRFGRRRVLLASLAIFGLGSVLCAYAGSPGVFLAGRLFQGLAGAGITVMAL
HHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHHH
SALVVLFDEQERPRAVGIYQAANFVALPLGPILGGWMLSRFWWGWVFLLNVPVVVLAAVI
HHHHHHCCCCCCCCEEEEEHHCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GFVLIPESRSTQRPGLDPVGTAASASGLAMVIYGLVRAGERGWGSLDALLSMAAGAAVVV
HHEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHH
GFVWWERRLGRRPTGRPLVNPQLLRPGLFLWGSALAAVAGLAMIGVLFTMPQYFQGVRGT
HHHHHHHHHCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GTLGSGLRLLPLIGGMVVGAGLASRLAPAITTRLAAALGFILLAGGLIVGATTTSTSGTV
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCEE
FTAGWTALVGAGTGLALSVATAAALAGLSAERSGTESAVVQAFNKTSGPLGTAITGSVLV
EECCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHH
AVYHARLDSVGLPETVAATARRSLYGGTATAQAAGGPGLEQAVRAAFVDGMSAAFLVSAV
HHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHH
IAILGACVALAVLPRGRSRRTEAGQPTEEGTVDAVEH
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]