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The map label for this gene is rsbU [H]

Identifier: 158318723

GI number: 158318723

Start: 8518911

End: 8521304

Strand: Direct

Name: rsbU [H]

Synonym: Franean1_6994

Alternate gene names: 158318723

Gene position: 8518911-8521304 (Clockwise)

Preceding gene: 158318719

Following gene: 158318725

Centisome position: 94.84

GC content: 73.81

Gene sequence:

>2394_bases
GTGTCCCGGGCGTCGCAGAGTAGCGCCGACCCCCGCGACCACGCCGCGACGGGGCTACTCCATGTGATCGCCCGTCAGCA
GCGGGAGCTGGCGGAGCTCCGGGCGCGGTCCGCAGCCGACGCTCTGATCGACATGGCTGTCGGGGTCCTGGCCGAACGGC
TGTGCTGCTCGGTCACCGAGGCCGGTGACCAGCTGCGCCGTCTCGCATCCGCCTCGGGGGTCACCCAGGACGAGTTCGCC
GCCGAGGTGCTCGGCGGGACCGCCGGAACACTCCATCGACCCCCGCTCGACGACGGCGCCCGGCGCCGCCTGTGGCTGGC
CGAGGCCGCGGTCAGCCACGCCACCGATGGCTGCCCGGTCGCCGAGGCCGTGTTCACCGAGGTCCTGGCCCATCAGGGTG
CCGTCGCCGTGGCCTTCTGGATGCTGGAATCCGATGGCGCGCTCACCCTGGTGGGCGAGACCGGCCTGGGGCCGCTCGAG
GCGAGCCGGTGGCAACGCATCCCGCCGCAGCTGGACTGCGTGGCGATGCGCGCGGCCCGCGGCGCCACGCCGCAGTGGTG
GCCCGAGGGCTCACCGCCCGAGGCGAACGATCCGACCGACGTCCCGACCGACATCCCGACCGACATCCCGGCGGGCGGCC
GGGCGGGCGTCGGCTCGGTGCCGCGGGTGGGTCCCTGGCTCGGGGCGCGGGCGGCGCTGCCGTTCCTGCAGGCAGGCGCC
GTCGTGGGCGCCGTGGAGATCTGCTGGCCCGCCCCGCTCGCGGAGTTCACCGCCGGGCTCCGACGCGAGCTCGTCGCGCT
CGCGGACCTGTGCCTGCGCGGCCTGCACCCGGGCGGATTCTCCGCCGACACCCGCTCGGCGCAGCCACAGACCCTCGGCG
GGCGAACGGCCTGGCTGCCCGCCCTCCTCGACGCCGTCGCCGGGTCGGTGCTGCTGGCCCACGCGGTGCGTGCCGAGGAC
GGCGAGATCCTCGACTTCCACGTCGACCACGTGAACGAGGGCTTCGTCGACCCGGCCGGCAGGCACCCGGCCCAGCTGCG
CGGCCGGCGCCTGCTCGACCTCTACCCGCTCATGGCCGCCGACGCCGGCCTGCTCGAGCGGGCCGTGGCGGTCGTGCGTA
CCGGAGAGCGGTACCAGGCCGACGGCATCGCCCTGCTCGTCCTGGTCGACGACGTGCTCGTCGCCGAGGAGCTCGACGTC
CGCATCGCCCCCTTCTTCGACGGAGTCGTGATCAGTTGGCGGCCGGTCGGCGGCGGTGACGCGGGCGGTTCCCTGGCCGG
CCACCTGCAACGCCTCGGCCGGTTCGGCGGCTGGCAGGAGGACGTCCGCACCGGGGCCGTGCGCTGGACCGACCACGTCT
ACGAGCTCTTCCAGCGTGACCGCACGATGTCACCCGTCCCGCTCGACGACCTCGATCCGCACATCCACCCGGACGACCGG
GCGGCCGTGGACCACCTGCGTGACGCGCTGTTGCGGCTCGGCCGGGCTGCCTCGGGATCGTTCCGGGTCATCGGCAGCGA
CGGGACGCTGCGCCAGCTCCGCGCCTTCGCCGAGCCGGTGACCGACGCCGCCGGCGTGACGGTCGCCGTCCGCGGCATCT
ACCAGGACCTGACCAGCCACTACCGCACGCAGGTCGTTCTTGACGCCACCCGGGACCAGCTCGCCGATTCGGAGGCGCGG
GCCGACGGCCAGCATCAGCTCGCGCTCGCCCTGCAGCGGGCGATCCTGCCCAGCTCCGAGGAGCCCGTCGACCTCGGCGG
CCTCGCGGTCGCCGTCCGCTACCGCCCCGCCGAGCAGGAGCACCTTGTCGGTGGCGACTGGTATGACGCGGTCACCCTGC
CGACCGGCGAGGTCCTGCTCGTCGTCGGTGACGTCGCCGGGCACAGCATCAGGACCGTGGCCGGTATGGTGACCCTGCGC
AACAGCCTGCGCGGCCTCGCGGTCACCGGCGCCGGCCCCGGGCAGCTGCTGCGCTGGCTCAACAACGTCACCTACCACCT
CGCCGACAACATCACCGCCACCGTCATCTGTGGCCTTTACCGTCCCGCCGAGCGTGCGCTGCGCTGGGCCCGCGCCGGGC
ATCTGCCGCCCGTGCTCGTCCGGGACGGCTCCGCCCACGCCCTTCCGATGCCCGACGGGCTCCTGCTCGGCGTCGAACCC
GATGTCGACTACCAGGAAACCGTCCACGTTCTTGAGCCGGACGACGTCCTGCTTCTCTTCACCGACGGCCTCATCGAACG
CCGCGGAACCGGGCTGGACGAATCCCTCCACGCGCTGCTGCGGATCGCGGCCGCCCCGGGCTTCGACGTCTCGCACCGGG
CCGATCACCTGCTCGCGCACACCACCCCGGACACCGACGACGACACCTGCCTCATCGTCATCCGACAGTCCTGA

Upstream 100 bases:

>100_bases
TAGAGTAGACGGATTAGGGCTCACTTCTTGGTCACATACCGCTGCCTGGTCGGACCGCCACTCCCCGGAACCCCACTACC
CGGAGCGGACGAGGAGAGGC

Downstream 100 bases:

>100_bases
ACAGGTGCCGAGGTCAGCGCAGCCCGTGCCGACGGGCCAGCCGGACGAAAACGTCGTTGTAGCCGTACTCCCGCAGCGCG
GCCTCGAGCGTTTTACGGTA

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Sigma factor sigB regulation protein rsbU [H]

Number of amino acids: Translated: 797; Mature: 796

Protein sequence:

>797_residues
MSRASQSSADPRDHAATGLLHVIARQQRELAELRARSAADALIDMAVGVLAERLCCSVTEAGDQLRRLASASGVTQDEFA
AEVLGGTAGTLHRPPLDDGARRRLWLAEAAVSHATDGCPVAEAVFTEVLAHQGAVAVAFWMLESDGALTLVGETGLGPLE
ASRWQRIPPQLDCVAMRAARGATPQWWPEGSPPEANDPTDVPTDIPTDIPAGGRAGVGSVPRVGPWLGARAALPFLQAGA
VVGAVEICWPAPLAEFTAGLRRELVALADLCLRGLHPGGFSADTRSAQPQTLGGRTAWLPALLDAVAGSVLLAHAVRAED
GEILDFHVDHVNEGFVDPAGRHPAQLRGRRLLDLYPLMAADAGLLERAVAVVRTGERYQADGIALLVLVDDVLVAEELDV
RIAPFFDGVVISWRPVGGGDAGGSLAGHLQRLGRFGGWQEDVRTGAVRWTDHVYELFQRDRTMSPVPLDDLDPHIHPDDR
AAVDHLRDALLRLGRAASGSFRVIGSDGTLRQLRAFAEPVTDAAGVTVAVRGIYQDLTSHYRTQVVLDATRDQLADSEAR
ADGQHQLALALQRAILPSSEEPVDLGGLAVAVRYRPAEQEHLVGGDWYDAVTLPTGEVLLVVGDVAGHSIRTVAGMVTLR
NSLRGLAVTGAGPGQLLRWLNNVTYHLADNITATVICGLYRPAERALRWARAGHLPPVLVRDGSAHALPMPDGLLLGVEP
DVDYQETVHVLEPDDVLLLFTDGLIERRGTGLDESLHALLRIAAAPGFDVSHRADHLLAHTTPDTDDDTCLIVIRQS

Sequences:

>Translated_797_residues
MSRASQSSADPRDHAATGLLHVIARQQRELAELRARSAADALIDMAVGVLAERLCCSVTEAGDQLRRLASASGVTQDEFA
AEVLGGTAGTLHRPPLDDGARRRLWLAEAAVSHATDGCPVAEAVFTEVLAHQGAVAVAFWMLESDGALTLVGETGLGPLE
ASRWQRIPPQLDCVAMRAARGATPQWWPEGSPPEANDPTDVPTDIPTDIPAGGRAGVGSVPRVGPWLGARAALPFLQAGA
VVGAVEICWPAPLAEFTAGLRRELVALADLCLRGLHPGGFSADTRSAQPQTLGGRTAWLPALLDAVAGSVLLAHAVRAED
GEILDFHVDHVNEGFVDPAGRHPAQLRGRRLLDLYPLMAADAGLLERAVAVVRTGERYQADGIALLVLVDDVLVAEELDV
RIAPFFDGVVISWRPVGGGDAGGSLAGHLQRLGRFGGWQEDVRTGAVRWTDHVYELFQRDRTMSPVPLDDLDPHIHPDDR
AAVDHLRDALLRLGRAASGSFRVIGSDGTLRQLRAFAEPVTDAAGVTVAVRGIYQDLTSHYRTQVVLDATRDQLADSEAR
ADGQHQLALALQRAILPSSEEPVDLGGLAVAVRYRPAEQEHLVGGDWYDAVTLPTGEVLLVVGDVAGHSIRTVAGMVTLR
NSLRGLAVTGAGPGQLLRWLNNVTYHLADNITATVICGLYRPAERALRWARAGHLPPVLVRDGSAHALPMPDGLLLGVEP
DVDYQETVHVLEPDDVLLLFTDGLIERRGTGLDESLHALLRIAAAPGFDVSHRADHLLAHTTPDTDDDTCLIVIRQS
>Mature_796_residues
SRASQSSADPRDHAATGLLHVIARQQRELAELRARSAADALIDMAVGVLAERLCCSVTEAGDQLRRLASASGVTQDEFAA
EVLGGTAGTLHRPPLDDGARRRLWLAEAAVSHATDGCPVAEAVFTEVLAHQGAVAVAFWMLESDGALTLVGETGLGPLEA
SRWQRIPPQLDCVAMRAARGATPQWWPEGSPPEANDPTDVPTDIPTDIPAGGRAGVGSVPRVGPWLGARAALPFLQAGAV
VGAVEICWPAPLAEFTAGLRRELVALADLCLRGLHPGGFSADTRSAQPQTLGGRTAWLPALLDAVAGSVLLAHAVRAEDG
EILDFHVDHVNEGFVDPAGRHPAQLRGRRLLDLYPLMAADAGLLERAVAVVRTGERYQADGIALLVLVDDVLVAEELDVR
IAPFFDGVVISWRPVGGGDAGGSLAGHLQRLGRFGGWQEDVRTGAVRWTDHVYELFQRDRTMSPVPLDDLDPHIHPDDRA
AVDHLRDALLRLGRAASGSFRVIGSDGTLRQLRAFAEPVTDAAGVTVAVRGIYQDLTSHYRTQVVLDATRDQLADSEARA
DGQHQLALALQRAILPSSEEPVDLGGLAVAVRYRPAEQEHLVGGDWYDAVTLPTGEVLLVVGDVAGHSIRTVAGMVTLRN
SLRGLAVTGAGPGQLLRWLNNVTYHLADNITATVICGLYRPAERALRWARAGHLPPVLVRDGSAHALPMPDGLLLGVEPD
VDYQETVHVLEPDDVLLLFTDGLIERRGTGLDESLHALLRIAAAPGFDVSHRADHLLAHTTPDTDDDTCLIVIRQS

Specific function: Positive regulator of sigma-B activity. Dephosphorylates rsbV in response to environmental stress conveyed from the rsbXST module [H]

COG id: COG2208

COG function: function code TK; Serine phosphatase RsbU, regulator of sigma subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017944
- InterPro:   IPR001932
- InterPro:   IPR014787
- InterPro:   IPR010822
- ProDom:   PD685490 [H]

Pfam domain/function: PF08673 RsbU_N; PF07228 SpoIIE [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 85005; Mature: 84874

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: PS50921 ANTAR ; PS50113 PAC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRASQSSADPRDHAATGLLHVIARQQRELAELRARSAADALIDMAVGVLAERLCCSVTE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGDQLRRLASASGVTQDEFAAEVLGGTAGTLHRPPLDDGARRRLWLAEAAVSHATDGCPV
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCH
AEAVFTEVLAHQGAVAVAFWMLESDGALTLVGETGLGPLEASRWQRIPPQLDCVAMRAAR
HHHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHC
GATPQWWPEGSPPEANDPTDVPTDIPTDIPAGGRAGVGSVPRVGPWLGARAALPFLQAGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCH
VVGAVEICWPAPLAEFTAGLRRELVALADLCLRGLHPGGFSADTRSAQPQTLGGRTAWLP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
ALLDAVAGSVLLAHAVRAEDGEILDFHVDHVNEGFVDPAGRHPAQLRGRRLLDLYPLMAA
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHC
DAGLLERAVAVVRTGERYQADGIALLVLVDDVLVAEELDVRIAPFFDGVVISWRPVGGGD
CHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHCCEEEEECCCCEEEEEEECCCCC
AGGSLAGHLQRLGRFGGWQEDVRTGAVRWTDHVYELFQRDRTMSPVPLDDLDPHIHPDDR
CCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
AAVDHLRDALLRLGRAASGSFRVIGSDGTLRQLRAFAEPVTDAAGVTVAVRGIYQDLTSH
HHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
YRTQVVLDATRDQLADSEARADGQHQLALALQRAILPSSEEPVDLGGLAVAVRYRPAEQE
HHEEEEEECHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCC
HLVGGDWYDAVTLPTGEVLLVVGDVAGHSIRTVAGMVTLRNSLRGLAVTGAGPGQLLRWL
CCCCCCCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
NNVTYHLADNITATVICGLYRPAERALRWARAGHLPPVLVRDGSAHALPMPDGLLLGVEP
HHCEEEHHCCCEEEHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCC
DVDYQETVHVLEPDDVLLLFTDGLIERRGTGLDESLHALLRIAAAPGFDVSHRADHLLAH
CCCHHHEEEEECCCCEEEEEECCHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHCHHEEE
TTPDTDDDTCLIVIRQS
CCCCCCCCEEEEEEECC
>Mature Secondary Structure 
SRASQSSADPRDHAATGLLHVIARQQRELAELRARSAADALIDMAVGVLAERLCCSVTE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGDQLRRLASASGVTQDEFAAEVLGGTAGTLHRPPLDDGARRRLWLAEAAVSHATDGCPV
HHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCH
AEAVFTEVLAHQGAVAVAFWMLESDGALTLVGETGLGPLEASRWQRIPPQLDCVAMRAAR
HHHHHHHHHHHCCCEEEEEEEEECCCCEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHC
GATPQWWPEGSPPEANDPTDVPTDIPTDIPAGGRAGVGSVPRVGPWLGARAALPFLQAGA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCH
VVGAVEICWPAPLAEFTAGLRRELVALADLCLRGLHPGGFSADTRSAQPQTLGGRTAWLP
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHH
ALLDAVAGSVLLAHAVRAEDGEILDFHVDHVNEGFVDPAGRHPAQLRGRRLLDLYPLMAA
HHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHC
DAGLLERAVAVVRTGERYQADGIALLVLVDDVLVAEELDVRIAPFFDGVVISWRPVGGGD
CHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHCCEEEEECCCCEEEEEEECCCCC
AGGSLAGHLQRLGRFGGWQEDVRTGAVRWTDHVYELFQRDRTMSPVPLDDLDPHIHPDDR
CCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHH
AAVDHLRDALLRLGRAASGSFRVIGSDGTLRQLRAFAEPVTDAAGVTVAVRGIYQDLTSH
HHHHHHHHHHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
YRTQVVLDATRDQLADSEARADGQHQLALALQRAILPSSEEPVDLGGLAVAVRYRPAEQE
HHEEEEEECHHHHHCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEECCCCCC
HLVGGDWYDAVTLPTGEVLLVVGDVAGHSIRTVAGMVTLRNSLRGLAVTGAGPGQLLRWL
CCCCCCCCCEEECCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHH
NNVTYHLADNITATVICGLYRPAERALRWARAGHLPPVLVRDGSAHALPMPDGLLLGVEP
HHCEEEHHCCCEEEHHHHCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCEEEECCC
DVDYQETVHVLEPDDVLLLFTDGLIERRGTGLDESLHALLRIAAAPGFDVSHRADHLLAH
CCCHHHEEEEECCCCEEEEEECCHHHHCCCCCCHHHHHHHHHHCCCCCCCCHHHCHHEEE
TTPDTDDDTCLIVIRQS
CCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8002610; 8002609; 9384377; 8824586; 9786195; 12499568 [H]