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The map label for this gene is yciC [H]

Identifier: 158318719

GI number: 158318719

Start: 8512519

End: 8513601

Strand: Direct

Name: yciC [H]

Synonym: Franean1_6990

Alternate gene names: 158318719

Gene position: 8512519-8513601 (Clockwise)

Preceding gene: 158318718

Following gene: 158318723

Centisome position: 94.77

GC content: 73.96

Gene sequence:

>1083_bases
ATGGTCGTGCGGGTGCCCGTGATCGCGCTGACCGGATACCTGGGTGCCGGCAAGACGACGGTGCTCAACCACCTGCTCCA
GGCCCCTGGGGCACGCCTTGGGGTCGTGGTCAACGACTTCGGGGCGATCAACGTGGACGCCGCGCTGGTCTCCGGTCAGG
TGGACCAGCCGGCCTCGATCGCGGGCGGCTGCCTGTGCTGCCTGCCGGACACGGACGGCCTGGACCAGGCGCTGGAGAAG
CTGAGCCATCCCCGGCTGCGGCTGGACGCGGTGATCGTGGAGGCCAGCGGCGTCGCCGACCCGCCGGCGCTGGCCAGGCT
CATCCGGTTCAGCGGTGTGGACCGCGTGCGCCCCGGCGGTCTCGTCGACGTGATCGACGCCCCCGCCTACTTCGACACCG
TCGACACGGGCGGGCTGCCGCCGGCCCGGTTCGCGTCCGCCTCGCTCGTCGTCATCAACAAGACCGACCGGATCCCGCCG
GCGCGGCGTGCCGAGACGTTGGCGCGGATCACCGGCCGGGTGCGCGAGAGCAACCCGCACGCCCACATCGTCGACACGAC
GCACGGCCGCGTCGACCCGGTGCTCGTGTTCGACGCCGCGAACCCGTACGACCCGGTCGACGAGCTCCCGCTCGCGGCCC
TGGCCCGGCACGACCACGAAGACGGTCACGACCCGCACCCGCGGGTCGACGCGGTGACCGTTCCCGCCGCCGGTCCGATC
GATCCCGGCCCGCTGGTCGACCTGCTCGAGGATCCCCCCGCGAACGTCTACCGGCTCAAGGGCACCGTGACCGTGGAGAC
GGCGCGGGGACCGCGCGGCTATGTGGTCAACGTCGTCGGACGGGAGATCAACGTCGCGACCAGACCCGGCGCTGTCAGAC
CCGGCGCTGCCAGGCCCGGCACTGCCAGGCCCGGCACTGCCAGGCCCGCGGCGGACGATGCCAGCGGTCTGGTCGCGATC
GGCATGCGTCTCGACCAGGCCGCCGTCCGCGCCCGTCTCGAGGCGGCCCTCCAGCCGTGCCCCGGTCGCCCCGCCGCGGA
CGGGGTCCGCCGCCTCGCCCGCTACCGGCGCCTGAGCACCTGA

Upstream 100 bases:

>100_bases
CTGGCAGCCCGGGTGGACGGTCCTCGTAGCCTGAGTCCGGAAATCCGTGGGACCAGTCGACACGGATGGCTGGCCGCGGC
GCGGGAGGAGGCGGGTGGGA

Downstream 100 bases:

>100_bases
GCGGCCGCCGCTCCCTGGGATGTCCCGGGGCGTCCTATGAGAAGGCCTTCACCTGTGGAAGTACCTCCCCAGCCAGCATG
ATCACCTGCTCGAGGTAGCC

Product: cobalamin synthesis protein P47K

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MVVRVPVIALTGYLGAGKTTVLNHLLQAPGARLGVVVNDFGAINVDAALVSGQVDQPASIAGGCLCCLPDTDGLDQALEK
LSHPRLRLDAVIVEASGVADPPALARLIRFSGVDRVRPGGLVDVIDAPAYFDTVDTGGLPPARFASASLVVINKTDRIPP
ARRAETLARITGRVRESNPHAHIVDTTHGRVDPVLVFDAANPYDPVDELPLAALARHDHEDGHDPHPRVDAVTVPAAGPI
DPGPLVDLLEDPPANVYRLKGTVTVETARGPRGYVVNVVGREINVATRPGAVRPGAARPGTARPGTARPAADDASGLVAI
GMRLDQAAVRARLEAALQPCPGRPAADGVRRLARYRRLST

Sequences:

>Translated_360_residues
MVVRVPVIALTGYLGAGKTTVLNHLLQAPGARLGVVVNDFGAINVDAALVSGQVDQPASIAGGCLCCLPDTDGLDQALEK
LSHPRLRLDAVIVEASGVADPPALARLIRFSGVDRVRPGGLVDVIDAPAYFDTVDTGGLPPARFASASLVVINKTDRIPP
ARRAETLARITGRVRESNPHAHIVDTTHGRVDPVLVFDAANPYDPVDELPLAALARHDHEDGHDPHPRVDAVTVPAAGPI
DPGPLVDLLEDPPANVYRLKGTVTVETARGPRGYVVNVVGREINVATRPGAVRPGAARPGTARPGTARPAADDASGLVAI
GMRLDQAAVRARLEAALQPCPGRPAADGVRRLARYRRLST
>Mature_360_residues
MVVRVPVIALTGYLGAGKTTVLNHLLQAPGARLGVVVNDFGAINVDAALVSGQVDQPASIAGGCLCCLPDTDGLDQALEK
LSHPRLRLDAVIVEASGVADPPALARLIRFSGVDRVRPGGLVDVIDAPAYFDTVDTGGLPPARFASASLVVINKTDRIPP
ARRAETLARITGRVRESNPHAHIVDTTHGRVDPVLVFDAANPYDPVDELPLAALARHDHEDGHDPHPRVDAVTVPAAGPI
DPGPLVDLLEDPPANVYRLKGTVTVETARGPRGYVVNVVGREINVATRPGAVRPGAARPGTARPGTARPAADDASGLVAI
GMRLDQAAVRARLEAALQPCPGRPAADGVRRLARYRRLST

Specific function: May bind GTP. Might act as metal chaperone (Potential). Contributes to optimal growth under starvation for zinc [H]

COG id: COG0523

COG function: function code R; Putative GTPases (G3E family)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cobW C-terminal domain [H]

Homologues:

Organism=Homo sapiens, GI33469141, Length=251, Percent_Identity=29.4820717131474, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI126722884, Length=251, Percent_Identity=29.4820717131474, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI148727351, Length=251, Percent_Identity=29.0836653386454, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI146231952, Length=251, Percent_Identity=29.0836653386454, Blast_Score=95, Evalue=8e-20,
Organism=Homo sapiens, GI223941779, Length=207, Percent_Identity=29.4685990338164, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI223941776, Length=240, Percent_Identity=28.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI119120938, Length=134, Percent_Identity=32.089552238806, Blast_Score=75, Evalue=7e-14,
Organism=Escherichia coli, GI87082430, Length=341, Percent_Identity=25.5131964809384, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1788499, Length=234, Percent_Identity=27.3504273504274, Blast_Score=75, Evalue=6e-15,
Organism=Saccharomyces cerevisiae, GI6324356, Length=228, Percent_Identity=26.7543859649123, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003495
- InterPro:   IPR011629 [H]

Pfam domain/function: PF02492 cobW; PF07683 CobW_C [H]

EC number: NA

Molecular weight: Translated: 37668; Mature: 37668

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVRVPVIALTGYLGAGKTTVLNHLLQAPGARLGVVVNDFGAINVDAALVSGQVDQPASI
CEEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEECHHEECCCCCCCCHH
AGGCLCCLPDTDGLDQALEKLSHPRLRLDAVIVEASGVADPPALARLIRFSGVDRVRPGG
CCCEEEECCCCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCC
LVDVIDAPAYFDTVDTGGLPPARFASASLVVINKTDRIPPARRAETLARITGRVRESNPH
EEEEECCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
AHIVDTTHGRVDPVLVFDAANPYDPVDELPLAALARHDHEDGHDPHPRVDAVTVPAAGPI
EEEEECCCCCCCEEEEEECCCCCCCHHHCHHHHHHHCCCCCCCCCCCCCCEEECCCCCCC
DPGPLVDLLEDPPANVYRLKGTVTVETARGPRGYVVNVVGREINVATRPGAVRPGAARPG
CCCCHHHHHCCCCCCEEEEEEEEEEEECCCCCCEEEEEECCEEEEEECCCCCCCCCCCCC
TARPGTARPAADDASGLVAIGMRLDQAAVRARLEAALQPCPGRPAADGVRRLARYRRLST
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVVRVPVIALTGYLGAGKTTVLNHLLQAPGARLGVVVNDFGAINVDAALVSGQVDQPASI
CEEEEEEEEEECCCCCCHHHHHHHHHHCCCCEEEEEEECCCCEEECHHEECCCCCCCCHH
AGGCLCCLPDTDGLDQALEKLSHPRLRLDAVIVEASGVADPPALARLIRFSGVDRVRPGG
CCCEEEECCCCCCHHHHHHHHCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCC
LVDVIDAPAYFDTVDTGGLPPARFASASLVVINKTDRIPPARRAETLARITGRVRESNPH
EEEEECCCCCCCCCCCCCCCCHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCC
AHIVDTTHGRVDPVLVFDAANPYDPVDELPLAALARHDHEDGHDPHPRVDAVTVPAAGPI
EEEEECCCCCCCEEEEEECCCCCCCHHHCHHHHHHHCCCCCCCCCCCCCCEEECCCCCCC
DPGPLVDLLEDPPANVYRLKGTVTVETARGPRGYVVNVVGREINVATRPGAVRPGAARPG
CCCCHHHHHCCCCCCEEEEEEEEEEEECCCCCCEEEEEECCEEEEEECCCCCCCCCCCCC
TARPGTARPAADDASGLVAIGMRLDQAAVRARLEAALQPCPGRPAADGVRRLARYRRLST
CCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969502; 9384377; 9811636 [H]