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The map label for this gene is recQ [H]

Identifier: 158318205

GI number: 158318205

Start: 7864485

End: 7866359

Strand: Reverse

Name: recQ [H]

Synonym: Franean1_6470

Alternate gene names: 158318205

Gene position: 7866359-7864485 (Counterclockwise)

Preceding gene: 158318206

Following gene: 158318204

Centisome position: 87.58

GC content: 74.61

Gene sequence:

>1875_bases
ATGCCTGAGGAGGCGGTGGTGGCCGAGGCGGTGGTGGCGGACACCGCCAGCCCCGATCCGCCGCGGGACGACGAGGAACA
CGCAGAGGAACACACAGAGCTGGACGACCTGCTGCGGGCCGTGGCCCGGGAGGGCTTCGGGTTCGCCGAGCTGCGTCCCG
GCCAACTCGAGGCGATGCGGGCCGTCACCGCCGGCCGGGACATGCTGTGCGTCCTGCCGACCGGGGGTGGCAAGTCGGCC
GTTTACCAGATTCCGGCCCTGCTCACGGCGGGGCCGACCGTGGTCGTCTCGCCGCTCATCGCGCTGCAGCGCGACCAGGT
GCGCGGGCTCACCGAACGCCTGGGCGGCCTGCTGGACGCGGTGCCCGCCGGCCCCGGGACCGCCGCCAGACCCGACGCCG
GCCAGTCCGGTGCGCGTCAGCCTGACGCTGACGCGCCCGCGGTGGCGGCGAACTCGCAGAGCGGGCGCGGCGCGGCGCTC
GCGGCGATCGACGCCGTCCGCCACGGCCGGGCCGAGTTCCTGTTCCTTGCTCCCGAGCAGCTCGCCCGCGACGACGTCCG
GGAGGCGCTTCGCGAGGCGCGGCCCTCCCTGTTCGTCGTGGACGAGGCGCACTGCATCTCCAGCTGGGGCCACGACTTCC
GCCCCGACTACGCCCGCCTGGGCCAGGTGATCGACGACCTCGGCCATCCGGTGGTCGTCGCGCTGACAGCCACCGCGTCG
CCGCCGGTGCGCCGGGAGATAGCCGAGCGCCTGCGGCTCGAGGATCCGGCGGAGATCGTCCGCGGCTTCGACCGCCCGGA
GATCACCCTGAGTGTCGAGTCGTTCGTCGACGACGACGAGAAGAAGGCCCGGCTGGTCGAGCGGATCGCCGCCGAGACCA
AGCCCGGCCTGGTCTACACGGCGACCCGGCGTGGCGCCGAGGATCTCGCCGCCGAGCTCGCGGACCTCGGGCTCACCGCG
AGCGCGTACCACGCCGGGCTACGCGCGGCGCGCCGCCGTGAGGTCGAGGAGGACTTCATGGCCGACCGGTGCGACGTCGT
CGTGGCGACGACCGCGTTCGGCATGGGCATCGACAAGCCCAACGTCAGGTTTGTGATCCACGCCGAGGTGGCCGACTCGA
TCGACTCCTACTACCAGGAGATCGGACGCGCCGGCCGCGACGGCCAGCCGGCGGTCGCGGTCCTGTTCTACCGGCCCGAG
GACCTGGGCCTGCGTCGCTTCTTCGCCTCGTCACGCCCGGACGAGACCGCCCTGCGCCGCGTCGCCGTGCTGCTCGGCCA
CGCCGAGGAACCGGTGAGCGCGCGCGCCCTGGCCGACGCCGCCGGGGTCGGCGACACCGCGCTGACCCGCATGGTGGACC
TGCTCGAACGGGCCGACGCGGTCACCGTCCACGACGACGGCCGCATCGAGCGCAGTGCCGGTGCGCCGGAACCCGAGCAG
GCCGCGGGCCGCGCCGTCGAACTGGCCGCGGCGCGGGTCGAGTTCGAGCGGTCGCGGGTCGACATGATGCGCGGGTACGC
GGAGACCCGCGACTGCCGGCGGCGTTACCTGCTCGCCTACTTCGGCGACACGTCCCCCGCCGCCTGCGGGAACTGTGACG
TGTGCCGGTCCCGTCTGCCCGGGCAGCGGGTGCCGGGCGGCGAGGGCGGGGCCGCGGCCGCCGCCGGTTCCCCGGCGCCG
GTGGGCGACAACGAGGCCACGGCGGAGGTCTCGCCGTTCCCGGCCGGGCTGGCCGTCCGTCATGTGCGGTGGGGGCCCGG
CCAGGTGATGAAGGAGGACGGCGACCGCATCACCGTCCTGTTCGACGAGGTCGGATACCGCACGCTGTCGGTGGCGGCGG
TGACCGAGCGGGGCCTGCTGGCGGTCGCCGACTAG

Upstream 100 bases:

>100_bases
TCCGGCACGCACCCGGTTGGCGGGCTGGTTGCGCCGTCTGCCGCTGCAACGCCGCAACCGCGATAGCCCCGCCCCGCCGC
CCGCGTCACCGCCCCCTCCC

Downstream 100 bases:

>100_bases
CCCCGCTGTAACGTCACCGCCGGCCCGCGCTGGCCGGTCGTTTCGTCAGCGACCGCGGTGCCCCGCACCGTCGAGGTCGG
GCGCGGCCAGTCCGTCCCCG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 623

Protein sequence:

>624_residues
MPEEAVVAEAVVADTASPDPPRDDEEHAEEHTELDDLLRAVAREGFGFAELRPGQLEAMRAVTAGRDMLCVLPTGGGKSA
VYQIPALLTAGPTVVVSPLIALQRDQVRGLTERLGGLLDAVPAGPGTAARPDAGQSGARQPDADAPAVAANSQSGRGAAL
AAIDAVRHGRAEFLFLAPEQLARDDVREALREARPSLFVVDEAHCISSWGHDFRPDYARLGQVIDDLGHPVVVALTATAS
PPVRREIAERLRLEDPAEIVRGFDRPEITLSVESFVDDDEKKARLVERIAAETKPGLVYTATRRGAEDLAAELADLGLTA
SAYHAGLRAARRREVEEDFMADRCDVVVATTAFGMGIDKPNVRFVIHAEVADSIDSYYQEIGRAGRDGQPAVAVLFYRPE
DLGLRRFFASSRPDETALRRVAVLLGHAEEPVSARALADAAGVGDTALTRMVDLLERADAVTVHDDGRIERSAGAPEPEQ
AAGRAVELAAARVEFERSRVDMMRGYAETRDCRRRYLLAYFGDTSPAACGNCDVCRSRLPGQRVPGGEGGAAAAAGSPAP
VGDNEATAEVSPFPAGLAVRHVRWGPGQVMKEDGDRITVLFDEVGYRTLSVAAVTERGLLAVAD

Sequences:

>Translated_624_residues
MPEEAVVAEAVVADTASPDPPRDDEEHAEEHTELDDLLRAVAREGFGFAELRPGQLEAMRAVTAGRDMLCVLPTGGGKSA
VYQIPALLTAGPTVVVSPLIALQRDQVRGLTERLGGLLDAVPAGPGTAARPDAGQSGARQPDADAPAVAANSQSGRGAAL
AAIDAVRHGRAEFLFLAPEQLARDDVREALREARPSLFVVDEAHCISSWGHDFRPDYARLGQVIDDLGHPVVVALTATAS
PPVRREIAERLRLEDPAEIVRGFDRPEITLSVESFVDDDEKKARLVERIAAETKPGLVYTATRRGAEDLAAELADLGLTA
SAYHAGLRAARRREVEEDFMADRCDVVVATTAFGMGIDKPNVRFVIHAEVADSIDSYYQEIGRAGRDGQPAVAVLFYRPE
DLGLRRFFASSRPDETALRRVAVLLGHAEEPVSARALADAAGVGDTALTRMVDLLERADAVTVHDDGRIERSAGAPEPEQ
AAGRAVELAAARVEFERSRVDMMRGYAETRDCRRRYLLAYFGDTSPAACGNCDVCRSRLPGQRVPGGEGGAAAAAGSPAP
VGDNEATAEVSPFPAGLAVRHVRWGPGQVMKEDGDRITVLFDEVGYRTLSVAAVTERGLLAVAD
>Mature_623_residues
PEEAVVAEAVVADTASPDPPRDDEEHAEEHTELDDLLRAVAREGFGFAELRPGQLEAMRAVTAGRDMLCVLPTGGGKSAV
YQIPALLTAGPTVVVSPLIALQRDQVRGLTERLGGLLDAVPAGPGTAARPDAGQSGARQPDADAPAVAANSQSGRGAALA
AIDAVRHGRAEFLFLAPEQLARDDVREALREARPSLFVVDEAHCISSWGHDFRPDYARLGQVIDDLGHPVVVALTATASP
PVRREIAERLRLEDPAEIVRGFDRPEITLSVESFVDDDEKKARLVERIAAETKPGLVYTATRRGAEDLAAELADLGLTAS
AYHAGLRAARRREVEEDFMADRCDVVVATTAFGMGIDKPNVRFVIHAEVADSIDSYYQEIGRAGRDGQPAVAVLFYRPED
LGLRRFFASSRPDETALRRVAVLLGHAEEPVSARALADAAGVGDTALTRMVDLLERADAVTVHDDGRIERSAGAPEPEQA
AGRAVELAAARVEFERSRVDMMRGYAETRDCRRRYLLAYFGDTSPAACGNCDVCRSRLPGQRVPGGEGGAAAAAGSPAPV
GDNEATAEVSPFPAGLAVRHVRWGPGQVMKEDGDRITVLFDEVGYRTLSVAAVTERGLLAVAD

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=428, Percent_Identity=34.3457943925234, Blast_Score=231, Evalue=1e-60,
Organism=Homo sapiens, GI51242943, Length=388, Percent_Identity=38.4020618556701, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI51242947, Length=388, Percent_Identity=38.4020618556701, Blast_Score=230, Evalue=4e-60,
Organism=Homo sapiens, GI148612816, Length=383, Percent_Identity=38.3812010443864, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI14591902, Length=379, Percent_Identity=34.5646437994723, Blast_Score=224, Evalue=3e-58,
Organism=Homo sapiens, GI14591904, Length=379, Percent_Identity=34.5646437994723, Blast_Score=224, Evalue=3e-58,
Organism=Homo sapiens, GI169218196, Length=387, Percent_Identity=30.2325581395349, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI110735439, Length=387, Percent_Identity=29.9741602067183, Blast_Score=193, Evalue=4e-49,
Organism=Homo sapiens, GI284005309, Length=405, Percent_Identity=34.0740740740741, Blast_Score=177, Evalue=2e-44,
Organism=Homo sapiens, GI45446747, Length=400, Percent_Identity=25.75, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI45446743, Length=400, Percent_Identity=25.75, Blast_Score=87, Evalue=6e-17,
Organism=Homo sapiens, GI41327771, Length=399, Percent_Identity=25.5639097744361, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI188035877, Length=220, Percent_Identity=25.9090909090909, Blast_Score=70, Evalue=4e-12,
Organism=Escherichia coli, GI48994977, Length=376, Percent_Identity=44.4148936170213, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1787016, Length=360, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI32564293, Length=402, Percent_Identity=36.0696517412935, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI25145561, Length=390, Percent_Identity=36.1538461538462, Blast_Score=224, Evalue=1e-58,
Organism=Caenorhabditis elegans, GI71987997, Length=416, Percent_Identity=33.8942307692308, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI71987993, Length=416, Percent_Identity=33.8942307692308, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17552866, Length=373, Percent_Identity=35.3887399463807, Blast_Score=196, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI32565321, Length=409, Percent_Identity=24.4498777506112, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17510309, Length=134, Percent_Identity=32.8358208955224, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17510307, Length=134, Percent_Identity=32.8358208955224, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995514, Length=134, Percent_Identity=32.8358208955224, Blast_Score=78, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71995718, Length=375, Percent_Identity=25.0666666666667, Blast_Score=75, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI71995724, Length=401, Percent_Identity=22.9426433915212, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17507121, Length=401, Percent_Identity=22.9426433915212, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323844, Length=377, Percent_Identity=33.1564986737401, Blast_Score=222, Evalue=1e-58,
Organism=Saccharomyces cerevisiae, GI6325138, Length=131, Percent_Identity=34.3511450381679, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324217, Length=219, Percent_Identity=27.3972602739726, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6324778, Length=131, Percent_Identity=29.0076335877863, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646066, Length=483, Percent_Identity=31.8840579710145, Blast_Score=234, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24664226, Length=369, Percent_Identity=34.9593495934959, Blast_Score=206, Evalue=5e-53,
Organism=Drosophila melanogaster, GI24664230, Length=372, Percent_Identity=34.6774193548387, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI62472181, Length=372, Percent_Identity=34.6774193548387, Blast_Score=204, Evalue=2e-52,
Organism=Drosophila melanogaster, GI21358123, Length=410, Percent_Identity=31.219512195122, Blast_Score=174, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24584399, Length=120, Percent_Identity=30, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI24584994, Length=176, Percent_Identity=30.1136363636364, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 66571; Mature: 66440

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS00690 DEAH_ATP_HELICASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEEAVVAEAVVADTASPDPPRDDEEHAEEHTELDDLLRAVAREGFGFAELRPGQLEAMR
CCCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
AVTAGRDMLCVLPTGGGKSAVYQIPALLTAGPTVVVSPLIALQRDQVRGLTERLGGLLDA
HHHCCCCEEEEEECCCCCCHHEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPAGPGTAARPDAGQSGARQPDADAPAVAANSQSGRGAALAAIDAVRHGRAEFLFLAPEQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCCCEEEEECHHH
LARDDVREALREARPSLFVVDEAHCISSWGHDFRPDYARLGQVIDDLGHPVVVALTATAS
HHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCC
PPVRREIAERLRLEDPAEIVRGFDRPEITLSVESFVDDDEKKARLVERIAAETKPGLVYT
CHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHCCCCCEEEE
ATRRGAEDLAAELADLGLTASAYHAGLRAARRREVEEDFMADRCDVVVATTAFGMGIDKP
ECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCC
NVRFVIHAEVADSIDSYYQEIGRAGRDGQPAVAVLFYRPEDLGLRRFFASSRPDETALRR
CEEEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHH
VAVLLGHAEEPVSARALADAAGVGDTALTRMVDLLERADAVTVHDDGRIERSAGAPEPEQ
HHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCEECCCCCCCHHH
AAGRAVELAAARVEFERSRVDMMRGYAETRDCRRRYLLAYFGDTSPAACGNCDVCRSRLP
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHCCC
GQRVPGGEGGAAAAAGSPAPVGDNEATAEVSPFPAGLAVRHVRWGPGQVMKEDGDRITVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCEEEEE
FDEVGYRTLSVAAVTERGLLAVAD
EECCCCEEEEEEEECCCCEEEECC
>Mature Secondary Structure 
PEEAVVAEAVVADTASPDPPRDDEEHAEEHTELDDLLRAVAREGFGFAELRPGQLEAMR
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCHHHHHH
AVTAGRDMLCVLPTGGGKSAVYQIPALLTAGPTVVVSPLIALQRDQVRGLTERLGGLLDA
HHHCCCCEEEEEECCCCCCHHEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPAGPGTAARPDAGQSGARQPDADAPAVAANSQSGRGAALAAIDAVRHGRAEFLFLAPEQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHCCCCEEEEECHHH
LARDDVREALREARPSLFVVDEAHCISSWGHDFRPDYARLGQVIDDLGHPVVVALTATAS
HHHHHHHHHHHHCCCCEEEEECHHHHHHCCCCCCCCHHHHHHHHHHCCCCEEEEEEECCC
PPVRREIAERLRLEDPAEIVRGFDRPEITLSVESFVDDDEKKARLVERIAAETKPGLVYT
CHHHHHHHHHHCCCCHHHHHHCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHCCCCCEEEE
ATRRGAEDLAAELADLGLTASAYHAGLRAARRREVEEDFMADRCDVVVATTAFGMGIDKP
ECCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHCCCCCC
NVRFVIHAEVADSIDSYYQEIGRAGRDGQPAVAVLFYRPEDLGLRRFFASSRPDETALRR
CEEEEEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHCCCCHHHHHHH
VAVLLGHAEEPVSARALADAAGVGDTALTRMVDLLERADAVTVHDDGRIERSAGAPEPEQ
HHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEEECCCCEECCCCCCCHHH
AAGRAVELAAARVEFERSRVDMMRGYAETRDCRRRYLLAYFGDTSPAACGNCDVCRSRLP
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCCCCCCCHHHHHHCCC
GQRVPGGEGGAAAAAGSPAPVGDNEATAEVSPFPAGLAVRHVRWGPGQVMKEDGDRITVL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHHHHCCCCEEEEE
FDEVGYRTLSVAAVTERGLLAVAD
EECCCCEEEEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]