| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is fabG [C]
Identifier: 158318204
GI number: 158318204
Start: 7863553
End: 7864344
Strand: Reverse
Name: fabG [C]
Synonym: Franean1_6469
Alternate gene names: 158318204
Gene position: 7864344-7863553 (Counterclockwise)
Preceding gene: 158318205
Following gene: 158318202
Centisome position: 87.56
GC content: 72.73
Gene sequence:
>792_bases TTGACCGACTTCCGGAACCGGACCGCGCTGGTCACGGGGGCCTCGTCGGGTATCGGGGCCGCGTTCGCCGAGGCGCTCGC GGCACGCGGGGCCGATCTCGTGCTCGCCGCGCCGTCCGAGGAGAAGCTGCGGCCGGTGGCCGAGCGGCTGCGCGCTCTGC ACGGGGTGCGGGTGTGGATGGTCCCGGTCGACCTCGCCCGGGAGGACGGCCCGGACCTGCTCGTCGAACAGGTCCGGGCG ACCGGTCGCGAGATCGACGTCCTGGTGAACAACGCCGGGTTCGGCACCTACGGCCGGTACGAGGAGCTGCCCGCCGACCG TGACCACCGCGAGGTCATGGTGGACGTCGTCGCGGTCGAACGGGTGACGCACCTGCTCCTGCCGGCGATGGTCGAGCGGG GCCGCGGCACCGTCGTCAACGTGTCGTCGACGTCGGGGTTCCAGGCCGTCCCGTACATGGCTGTGTACGGGGCGTCGAAG GCGTTCGTGTTGTCCTTCTCGATCGCGCTGTGGGCGGAGTACCGGTCGCGCGGAATCCGGGTGCTGGCGGTATGCCCGGG GCCGACCGACACGAACTTCTTCGAGGTCCTCGGCCGGCGGATGAGCGCCGGTGGACGGCTGCGCACCACCGACGAGGTCG TCTCGGCCGCCTTCCGCGGCCTCGACCGCGGCCTGCCCTACGTGATCGACGGCCGGCTCAACTACCTGACCTCGAACGCG TCCCGCCTGCTGGGCCGCGGGCTCGTCGCGGGGATCACGGCCCGGACACTCCGGCCGCGCGGGCGTCCCTGA
Upstream 100 bases:
>100_bases TTTCGTCAGCGACCGCGGTGCCCCGCACCGTCGAGGTCGGGCGCGGCCAGTCCGTCCCCGCACGTCGCCGATTGCCGCCG ACCTGAGGAGCACCGCTTTC
Downstream 100 bases:
>100_bases CCTGCCCGACCCCCGGTTCGTCCAGGGCCAGCCGGGCGACGAGCTCGTAGGAGCGGATCCGGTCGGCGTTGGAGTGCACG TTCGTGACGATCATCAGCTC
Product: short-chain dehydrogenase/reductase SDR
Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]
Alternate protein names: NA
Number of amino acids: Translated: 263; Mature: 262
Protein sequence:
>263_residues MTDFRNRTALVTGASSGIGAAFAEALAARGADLVLAAPSEEKLRPVAERLRALHGVRVWMVPVDLAREDGPDLLVEQVRA TGREIDVLVNNAGFGTYGRYEELPADRDHREVMVDVVAVERVTHLLLPAMVERGRGTVVNVSSTSGFQAVPYMAVYGASK AFVLSFSIALWAEYRSRGIRVLAVCPGPTDTNFFEVLGRRMSAGGRLRTTDEVVSAAFRGLDRGLPYVIDGRLNYLTSNA SRLLGRGLVAGITARTLRPRGRP
Sequences:
>Translated_263_residues MTDFRNRTALVTGASSGIGAAFAEALAARGADLVLAAPSEEKLRPVAERLRALHGVRVWMVPVDLAREDGPDLLVEQVRA TGREIDVLVNNAGFGTYGRYEELPADRDHREVMVDVVAVERVTHLLLPAMVERGRGTVVNVSSTSGFQAVPYMAVYGASK AFVLSFSIALWAEYRSRGIRVLAVCPGPTDTNFFEVLGRRMSAGGRLRTTDEVVSAAFRGLDRGLPYVIDGRLNYLTSNA SRLLGRGLVAGITARTLRPRGRP >Mature_262_residues TDFRNRTALVTGASSGIGAAFAEALAARGADLVLAAPSEEKLRPVAERLRALHGVRVWMVPVDLAREDGPDLLVEQVRAT GREIDVLVNNAGFGTYGRYEELPADRDHREVMVDVVAVERVTHLLLPAMVERGRGTVVNVSSTSGFQAVPYMAVYGASKA FVLSFSIALWAEYRSRGIRVLAVCPGPTDTNFFEVLGRRMSAGGRLRTTDEVVSAAFRGLDRGLPYVIDGRLNYLTSNAS RLLGRGLVAGITARTLRPRGRP
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG0300
COG function: function code R; Short-chain dehydrogenases of various substrate specificities
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705855, Length=182, Percent_Identity=38.4615384615385, Blast_Score=122, Evalue=5e-28, Organism=Homo sapiens, GI226371731, Length=183, Percent_Identity=36.6120218579235, Blast_Score=108, Evalue=4e-24, Organism=Homo sapiens, GI4557649, Length=222, Percent_Identity=29.2792792792793, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI20149619, Length=195, Percent_Identity=30.7692307692308, Blast_Score=92, Evalue=4e-19, Organism=Homo sapiens, GI31542939, Length=220, Percent_Identity=30, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=30.9644670050761, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI40807363, Length=189, Percent_Identity=29.1005291005291, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI25282469, Length=275, Percent_Identity=26.9090909090909, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=28.9156626506024, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI210032110, Length=222, Percent_Identity=28.8288288288288, Blast_Score=75, Evalue=6e-14, Organism=Homo sapiens, GI142976729, Length=192, Percent_Identity=29.6875, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI33667109, Length=226, Percent_Identity=30.0884955752212, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI109715829, Length=209, Percent_Identity=28.7081339712919, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI5031737, Length=197, Percent_Identity=30.4568527918782, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI4503817, Length=190, Percent_Identity=27.3684210526316, Blast_Score=68, Evalue=9e-12, Organism=Homo sapiens, GI223718074, Length=196, Percent_Identity=31.6326530612245, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI150247226, Length=194, Percent_Identity=31.9587628865979, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI19923817, Length=190, Percent_Identity=26.3157894736842, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1787335, Length=221, Percent_Identity=32.579185520362, Blast_Score=96, Evalue=3e-21, Organism=Escherichia coli, GI87082100, Length=203, Percent_Identity=33.0049261083744, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1787820, Length=182, Percent_Identity=30.7692307692308, Blast_Score=80, Evalue=1e-16, Organism=Escherichia coli, GI1786701, Length=198, Percent_Identity=29.7979797979798, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI1790717, Length=191, Percent_Identity=27.7486910994764, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1789378, Length=187, Percent_Identity=29.4117647058824, Blast_Score=72, Evalue=3e-14, Organism=Escherichia coli, GI87082160, Length=186, Percent_Identity=27.9569892473118, Blast_Score=71, Evalue=6e-14, Organism=Escherichia coli, GI1788459, Length=187, Percent_Identity=31.0160427807487, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI1789208, Length=247, Percent_Identity=30.3643724696356, Blast_Score=69, Evalue=2e-13, Organism=Escherichia coli, GI2367365, Length=194, Percent_Identity=31.4432989690722, Blast_Score=64, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17562904, Length=207, Percent_Identity=32.3671497584541, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=36.0824742268041, Blast_Score=85, Evalue=4e-17, Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=29.7435897435897, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17562906, Length=207, Percent_Identity=33.8164251207729, Blast_Score=83, Evalue=2e-16, Organism=Caenorhabditis elegans, GI17508895, Length=247, Percent_Identity=26.3157894736842, Blast_Score=80, Evalue=9e-16, Organism=Caenorhabditis elegans, GI71994600, Length=217, Percent_Identity=33.1797235023041, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17563726, Length=205, Percent_Identity=30.2439024390244, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=29.3193717277487, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI71997402, Length=199, Percent_Identity=31.1557788944724, Blast_Score=78, Evalue=5e-15, Organism=Caenorhabditis elegans, GI17561402, Length=195, Percent_Identity=28.2051282051282, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI17551412, Length=201, Percent_Identity=32.3383084577114, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17544670, Length=207, Percent_Identity=31.4009661835749, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17562908, Length=207, Percent_Identity=32.3671497584541, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI193204405, Length=212, Percent_Identity=31.6037735849057, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17538486, Length=278, Percent_Identity=27.3381294964029, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI72000259, Length=206, Percent_Identity=31.0679611650485, Blast_Score=74, Evalue=7e-14, Organism=Caenorhabditis elegans, GI17538480, Length=202, Percent_Identity=29.2079207920792, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17570069, Length=192, Percent_Identity=29.1666666666667, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI25152911, Length=204, Percent_Identity=32.3529411764706, Blast_Score=72, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17560220, Length=206, Percent_Identity=27.1844660194175, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17562910, Length=207, Percent_Identity=28.9855072463768, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17560150, Length=214, Percent_Identity=27.1028037383178, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI212646214, Length=206, Percent_Identity=28.6407766990291, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17531453, Length=213, Percent_Identity=32.8638497652582, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17560676, Length=193, Percent_Identity=27.4611398963731, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17559104, Length=265, Percent_Identity=27.1698113207547, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17557668, Length=201, Percent_Identity=25.8706467661692, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560176, Length=192, Percent_Identity=28.125, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17560332, Length=209, Percent_Identity=29.6650717703349, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17562990, Length=207, Percent_Identity=28.9855072463768, Blast_Score=68, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6323882, Length=192, Percent_Identity=32.8125, Blast_Score=87, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6319635, Length=187, Percent_Identity=27.807486631016, Blast_Score=72, Evalue=1e-13, Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=39.7959183673469, Blast_Score=117, Evalue=8e-27, Organism=Drosophila melanogaster, GI28571526, Length=195, Percent_Identity=35.8974358974359, Blast_Score=107, Evalue=6e-24, Organism=Drosophila melanogaster, GI21357041, Length=187, Percent_Identity=34.7593582887701, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=35.4166666666667, Blast_Score=98, Evalue=5e-21, Organism=Drosophila melanogaster, GI21358495, Length=197, Percent_Identity=32.994923857868, Blast_Score=96, Evalue=3e-20, Organism=Drosophila melanogaster, GI24584744, Length=207, Percent_Identity=33.8164251207729, Blast_Score=96, Evalue=4e-20, Organism=Drosophila melanogaster, GI28574402, Length=207, Percent_Identity=33.8164251207729, Blast_Score=95, Evalue=4e-20, Organism=Drosophila melanogaster, GI24580925, Length=202, Percent_Identity=32.6732673267327, Blast_Score=93, Evalue=2e-19, Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=32.972972972973, Blast_Score=92, Evalue=5e-19, Organism=Drosophila melanogaster, GI161076933, Length=185, Percent_Identity=32.972972972973, Blast_Score=91, Evalue=6e-19, Organism=Drosophila melanogaster, GI23397609, Length=195, Percent_Identity=34.3589743589744, Blast_Score=91, Evalue=1e-18, Organism=Drosophila melanogaster, GI221331216, Length=227, Percent_Identity=32.15859030837, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24665247, Length=227, Percent_Identity=32.15859030837, Blast_Score=89, Evalue=2e-18, Organism=Drosophila melanogaster, GI24584752, Length=201, Percent_Identity=32.3383084577114, Blast_Score=87, Evalue=9e-18, Organism=Drosophila melanogaster, GI221331218, Length=227, Percent_Identity=31.7180616740088, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24665243, Length=227, Percent_Identity=31.7180616740088, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI17737361, Length=210, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI281364494, Length=210, Percent_Identity=31.9047619047619, Blast_Score=72, Evalue=3e-13, Organism=Drosophila melanogaster, GI24651139, Length=243, Percent_Identity=25.5144032921811, Blast_Score=71, Evalue=6e-13, Organism=Drosophila melanogaster, GI24643142, Length=185, Percent_Identity=32.972972972973, Blast_Score=71, Evalue=7e-13, Organism=Drosophila melanogaster, GI24639444, Length=195, Percent_Identity=31.7948717948718, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI21355319, Length=276, Percent_Identity=26.8115942028986, Blast_Score=65, Evalue=5e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.1.1.100 [C]
Molecular weight: Translated: 28481; Mature: 28350
Theoretical pI: Translated: 10.12; Mature: 10.12
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 2.7 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 1.9 %Met (Mature Protein) 2.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTDFRNRTALVTGASSGIGAAFAEALAARGADLVLAAPSEEKLRPVAERLRALHGVRVWM CCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCEEEE VPVDLAREDGPDLLVEQVRATGREIDVLVNNAGFGTYGRYEELPADRDHREVMVDVVAVE EEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHCCCCCCCHHHHHHHHHHHH RVTHLLLPAMVERGRGTVVNVSSTSGFQAVPYMAVYGASKAFVLSFSIALWAEYRSRGIR HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCCCCEEEEHHHHHHHHHHHHCCEE VLAVCPGPTDTNFFEVLGRRMSAGGRLRTTDEVVSAAFRGLDRGLPYVIDGRLNYLTSNA EEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH SRLLGRGLVAGITARTLRPRGRP HHHHHHHHHHHHHHHHCCCCCCC >Mature Secondary Structure TDFRNRTALVTGASSGIGAAFAEALAARGADLVLAAPSEEKLRPVAERLRALHGVRVWM CCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHCCEEEE VPVDLAREDGPDLLVEQVRATGREIDVLVNNAGFGTYGRYEELPADRDHREVMVDVVAVE EEEECCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCHHCCCCCCCHHHHHHHHHHHH RVTHLLLPAMVERGRGTVVNVSSTSGFQAVPYMAVYGASKAFVLSFSIALWAEYRSRGIR HHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCEECCCCCEEEEHHHHHHHHHHHHCCEE VLAVCPGPTDTNFFEVLGRRMSAGGRLRTTDEVVSAAFRGLDRGLPYVIDGRLNYLTSNA EEEECCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCHHHHHHHH SRLLGRGLVAGITARTLRPRGRP HHHHHHHHHHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NADPH [C]
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]
Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]
General reaction: Redox reaction [C]
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA