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The map label for this gene is cdd [H]

Identifier: 158317677

GI number: 158317677

Start: 7208577

End: 7209176

Strand: Reverse

Name: cdd [H]

Synonym: Franean1_5935

Alternate gene names: 158317677

Gene position: 7209176-7208577 (Counterclockwise)

Preceding gene: 158317681

Following gene: 158317676

Centisome position: 80.26

GC content: 74.83

Gene sequence:

>600_bases
ATGCTGGTCGGGGCCGGCGCCGACGGGCCGTGCGGGCCGGTCCGCCGGGCCCGGCGTGACGCGGTGCATCTGGTCGGCGA
CCTGGCGCATCCGGGCGGACAGCCTGGAAGGAAGGCGAACCGTCGGGGAGGGAACGTGGACGACAGCGGCTGGGAGCACC
TGCGGGGCGAGGCGGTGCGGGTGGCGCGGCACGCCTACGCGCCCTACTCGGGCCTGCGGGTCGGCGCTGCGGCGATGGTC
GACGACGGTCGGGTCGTCGTCGGTTGCAACGTAGAGAACGCCTCCTACGGGCTCACATTGTGCGCTGAATGTGGTCTTGT
CTCGGCGCTGCGGGCCAGCGGTGGTGGCCGGCTGGTCGCCTTCGCCTGTGTGGACGGCACGGGCGCGCCGCTCGCGCCGT
GCGGTCGCTGCCGCCAGCTTCTTCACGAGCACGGAGGTCCCGAGCTCGAACTGGCGACCGCGGACGGAATCCGTACCCTG
GGCGAGCTCCTCCCCGGCGCCTTCGGCCCGGCGGACCTGCCGCCCGCGGCGGAGCAGGCACCTGCGGTGGAGCGGGCACC
TGCGGCGGAGCGGGCACCTGCGGCGGAGCGCGGAGCATGA

Upstream 100 bases:

>100_bases
ACCGGGTTCGCCCCGGCGCTCGCCTGACATCGGTTGTCCTCTCCGCTGCGCGTTGACGATTTCATGGGATCACATCCGGT
CCGCTCACCGGCAGTGGGGC

Downstream 100 bases:

>100_bases
GCGCTGATGCCCCCGGCAGCGATCACGGCGGTCCTGCGGCGTCCCACGACGTCGTCGACCTCATCCGGGCCAAGCGCGAC
GGGGCGGCGCTGCCGGCGGA

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MLVGAGADGPCGPVRRARRDAVHLVGDLAHPGGQPGRKANRRGGNVDDSGWEHLRGEAVRVARHAYAPYSGLRVGAAAMV
DDGRVVVGCNVENASYGLTLCAECGLVSALRASGGGRLVAFACVDGTGAPLAPCGRCRQLLHEHGGPELELATADGIRTL
GELLPGAFGPADLPPAAEQAPAVERAPAAERAPAAERGA

Sequences:

>Translated_199_residues
MLVGAGADGPCGPVRRARRDAVHLVGDLAHPGGQPGRKANRRGGNVDDSGWEHLRGEAVRVARHAYAPYSGLRVGAAAMV
DDGRVVVGCNVENASYGLTLCAECGLVSALRASGGGRLVAFACVDGTGAPLAPCGRCRQLLHEHGGPELELATADGIRTL
GELLPGAFGPADLPPAAEQAPAVERAPAAERAPAAERGA
>Mature_199_residues
MLVGAGADGPCGPVRRARRDAVHLVGDLAHPGGQPGRKANRRGGNVDDSGWEHLRGEAVRVARHAYAPYSGLRVGAAAMV
DDGRVVVGCNVENASYGLTLCAECGLVSALRASGGGRLVAFACVDGTGAPLAPCGRCRQLLHEHGGPELELATADGIRTL
GELLPGAFGPADLPPAAEQAPAVERAPAAERAPAAERGA

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=116, Percent_Identity=39.6551724137931, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17551074, Length=128, Percent_Identity=42.96875, Blast_Score=90, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17540514, Length=150, Percent_Identity=38.6666666666667, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6323274, Length=142, Percent_Identity=33.8028169014084, Blast_Score=84, Evalue=1e-17,
Organism=Drosophila melanogaster, GI19920920, Length=145, Percent_Identity=33.1034482758621, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 20161; Mature: 20161

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVGAGADGPCGPVRRARRDAVHLVGDLAHPGGQPGRKANRRGGNVDDSGWEHLRGEAVR
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VARHAYAPYSGLRVGAAAMVDDGRVVVGCNVENASYGLTLCAECGLVSALRASGGGRLVA
HHHHHCCCCCCCEECCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
FACVDGTGAPLAPCGRCRQLLHEHGGPELELATADGIRTLGELLPGAFGPADLPPAAEQA
EEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCHHC
PAVERAPAAERAPAAERGA
CCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLVGAGADGPCGPVRRARRDAVHLVGDLAHPGGQPGRKANRRGGNVDDSGWEHLRGEAVR
CEECCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
VARHAYAPYSGLRVGAAAMVDDGRVVVGCNVENASYGLTLCAECGLVSALRASGGGRLVA
HHHHHCCCCCCCEECCEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCEEEE
FACVDGTGAPLAPCGRCRQLLHEHGGPELELATADGIRTLGELLPGAFGPADLPPAAEQA
EEEECCCCCCCCCHHHHHHHHHHCCCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCHHC
PAVERAPAAERAPAAERGA
CCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]