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The map label for this gene is ndhS [H]

Identifier: 158317431

GI number: 158317431

Start: 6900747

End: 6901259

Strand: Reverse

Name: ndhS [H]

Synonym: Franean1_5683

Alternate gene names: 158317431

Gene position: 6901259-6900747 (Counterclockwise)

Preceding gene: 158317432

Following gene: 158317430

Centisome position: 76.83

GC content: 77.0

Gene sequence:

>513_bases
GTGCCTGGTCACCTGGGCGGGGAGCGCCGGCTTTCCTACCACCTGAGCATCGACGGCTCCCGGCGCGCCGTTACCGGGGC
GCGGCTCGAGGAGTCGCTGCTGACGGTCCTGCGGGAGCGGCTCGACGTCACCTCCGTGAAGGACGCCTGCGAGCAGGGCC
GGTGCGGGGCCTGCTCGGTGCTGCTGGACGGCCGGCTGGTCACGGCCTGCACCGTCCTCGCCGCCGACGCCGCCGACGCC
CGCGTGGTCACCGTGGCCGGGCTGGGCCCGGGTGGGCCGGCCGCCGCGGTGCGCGCCGCCTTCGTCGCGCACGGGGCGGT
CCAGTGCGGCTTCTGCACCCCGGGCCTGGTCGTGGCGGTCACCGACCTGCTCGCCCGCCGACCGGGCGCCGACGAGGATG
AGATTCAGGAGACACTGGCGGGCAACATCTGCCGGTGCACCGGGTACGGCCGCATCCTCGCGGCGGTCCGCGCCGTCCAG
GCGGGGCGGGGCGGCCCGCCCGGGTGGGCATGA

Upstream 100 bases:

>100_bases
ACCGGGTGCACGCGGCCGGCGTGCTGGCCGCCCGGGCCTTCGCCCGATGCCTCACGGCCCGGTCGGCGCCGCGGCGCGAG
AGTGCCCCGTGAGCGGCGGC

Downstream 100 bases:

>100_bases
CCGGCCGGGCGCGAGGCGTCGGGGGATCGGTGCTCCGTCCCGACGGGTCGGCCAAGGCCGGCGGGACGTTCGTCTACGCC
GGCGACCTCAGCGCCCCCGG

Product: 2Fe-2S iron-sulfur cluster binding domain-containing protein

Products: NA

Alternate protein names: NDH; Nicotinic acid hydroxylase small FeS subunit; NAH [H]

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MPGHLGGERRLSYHLSIDGSRRAVTGARLEESLLTVLRERLDVTSVKDACEQGRCGACSVLLDGRLVTACTVLAADAADA
RVVTVAGLGPGGPAAAVRAAFVAHGAVQCGFCTPGLVVAVTDLLARRPGADEDEIQETLAGNICRCTGYGRILAAVRAVQ
AGRGGPPGWA

Sequences:

>Translated_170_residues
MPGHLGGERRLSYHLSIDGSRRAVTGARLEESLLTVLRERLDVTSVKDACEQGRCGACSVLLDGRLVTACTVLAADAADA
RVVTVAGLGPGGPAAAVRAAFVAHGAVQCGFCTPGLVVAVTDLLARRPGADEDEIQETLAGNICRCTGYGRILAAVRAVQ
AGRGGPPGWA
>Mature_169_residues
PGHLGGERRLSYHLSIDGSRRAVTGARLEESLLTVLRERLDVTSVKDACEQGRCGACSVLLDGRLVTACTVLAADAADAR
VVTVAGLGPGGPAAAVRAAFVAHGAVQCGFCTPGLVVAVTDLLARRPGADEDEIQETLAGNICRCTGYGRILAAVRAVQA
GRGGPPGWA

Specific function: Catalyzes the hydroxylation of nicotinate to 6- hydroxynicotinate. Also active against 2-pyrazinecarboxylic acid, but inactive against other nicotinate analogs [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=153, Percent_Identity=35.9477124183007, Blast_Score=66, Evalue=1e-11,
Organism=Homo sapiens, GI71773480, Length=91, Percent_Identity=38.4615384615385, Blast_Score=64, Evalue=5e-11,
Organism=Escherichia coli, GI1786480, Length=141, Percent_Identity=39.0070921985816, Blast_Score=104, Evalue=3e-24,
Organism=Escherichia coli, GI1789232, Length=126, Percent_Identity=46.8253968253968, Blast_Score=102, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI32566215, Length=146, Percent_Identity=32.8767123287671, Blast_Score=87, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17540638, Length=162, Percent_Identity=35.1851851851852, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17539860, Length=137, Percent_Identity=35.7664233576642, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24647199, Length=156, Percent_Identity=33.974358974359, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24647201, Length=156, Percent_Identity=32.6923076923077, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24647193, Length=158, Percent_Identity=31.6455696202532, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24647197, Length=163, Percent_Identity=28.8343558282209, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24647195, Length=163, Percent_Identity=28.8343558282209, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17737937, Length=159, Percent_Identity=33.9622641509434, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR006058
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.17.1.5 [H]

Molecular weight: Translated: 17390; Mature: 17259

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.7 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
4.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGHLGGERRLSYHLSIDGSRRAVTGARLEESLLTVLRERLDVTSVKDACEQGRCGACSV
CCCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEE
LLDGRLVTACTVLAADAADARVVTVAGLGPGGPAAAVRAAFVAHGAVQCGFCTPGLVVAV
EECCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHH
TDLLARRPGADEDEIQETLAGNICRCTGYGRILAAVRAVQAGRGGPPGWA
HHHHHCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
PGHLGGERRLSYHLSIDGSRRAVTGARLEESLLTVLRERLDVTSVKDACEQGRCGACSV
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEE
LLDGRLVTACTVLAADAADARVVTVAGLGPGGPAAAVRAAFVAHGAVQCGFCTPGLVVAV
EECCHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHHHHHHHHHCCEEECCCCCHHHHHH
TDLLARRPGADEDEIQETLAGNICRCTGYGRILAAVRAVQAGRGGPPGWA
HHHHHCCCCCCHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA