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The map label for this gene is ykuT [H]

Identifier: 158317068

GI number: 158317068

Start: 6396499

End: 6397863

Strand: Reverse

Name: ykuT [H]

Synonym: Franean1_5312

Alternate gene names: 158317068

Gene position: 6397863-6396499 (Counterclockwise)

Preceding gene: 158317071

Following gene: 158317067

Centisome position: 71.23

GC content: 69.6

Gene sequence:

>1365_bases
GTGTCCATCTCACGTGTCCCGTTTGGTGCTGTCCCGTTCGGTGGCGTGCCCGCCGAACCGGTCGCGGCCGGGCTGCCCCC
GGCTGTCATGGGTGCGGAGCCGTCCCTGCTGGCTCAGCCCGTGATCCCGATGCTCGGCGCGATCCTGTCGCCCACCGCCG
CACCGACGACCGCGGCGACGGTCTCGCCCAGCCCCATACCCTCGGTGTCGATCTCACCTGGTCCGACGACGGATCCGTTC
GTCTCGATCGAGGGTGTCGCCAACGCGCTGCGGGACGCCTGCGGCACGGACCCCGGCCTCATGTGCCGCACCGTGTACGA
CCTCACGCACAGTAACTATCTTGCGTCCGGTGCCGAGGTGTTCCTCGGTACGCCGATCAAGATTTCGCTGATTCTGCTGC
TCGCGATGGTGATCCGCACGCTGCTGCACCGGTTCATCCGGCGGACCACCGAACGGGCCGCCTCGGGGCGCAGCACCGGC
ATGCTGCGCGGGCTGCGGTCGAACACCTTGCTGGGCGCATTCGGTGATCCGACCGTTCTGCTCGAGCGGCGGCGCCAGCG
CGCCGGAACCGTCGGATCGCTGCTGCGCAGCGTGACGTCAATCTTTGTGTTCGGGCTGGCTTTCCTCACGATCCTCGGCG
AGCTCGGCCTGAATCTAGCCCCGATCGTGGCCAGCGCCGGAGTGCTCGGCATCGCCGTCGGTTTCGGTGCGCAGAACCTC
GTGCGCGACTTCCTGTCGGGCATGTTCATGCTGCTGGAGGACCAGTACGGCGTCGGTGACGTGATCGACGTCGGCCCGGT
CTCGGGCACCGTCGAGGCGGTGAGCCTGCGGATGACCCGATTGCGCGACGTCGAGGGGACGGTCTGGTACGTCCGCAACG
GCGAGATAACCCGGGTCGGGAACAAGAGCCAGCAGTGGGCACGCACCGTTCTCGACGTCCCGCTCGATTACGACACCGAG
GTCGCCGCCGCGAAACGGGTGCTCGTCCGGACGGCCGACAAGCTGTGGAAGGACGAGGCCTGGTCCGGCCTGATCCTCGC
CGAGCCGGAGGTCTGGGGCATGGAGACCATGACCGCGGACGGCTACACGCTGCGGATCGCCATCAAGACCCAGCCGCTCA
AGCAGTGGGACGTCGCCCGCGAGCTGCGGGAGCGGGTCCGGGCGTCGCTCGGCCGGGCCGGGATCGAGCTCGGCACCGTC
CAGCGCAGCGAGGTCGTGGTCGTCGACGACGATGACGACGACAAGCCCGCCGAGGAGGAGGAGACGCCGGGCGGCACCGG
CGGCTCGCCGGGCCAGGGCGCGGACGACGTGCCGACACCCAGGATCGATCCGCCCGCGCCGGCCCGTTCCGGGCATAGCG
CCTGA

Upstream 100 bases:

>100_bases
CCGCCTTGCCGCGGCCCGGCCGGGGGGCTTCCAGACGCACACGGCGCCCGATCGGCGTCGATCCGACTGAGAGACCTGCT
TACGGAGGATGGCCGGCGTT

Downstream 100 bases:

>100_bases
AGCGGGGCTGAGGATCGGACAAGGTCTTGCTGAGATGCGCGTCCGGAGCATGGAACTGTCGGGCGAGCGGGGCAGACTGG
AGCCGTGCGAGTACTGGTGG

Product: mechanosensitive ion channel MscS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSISRVPFGAVPFGGVPAEPVAAGLPPAVMGAEPSLLAQPVIPMLGAILSPTAAPTTAATVSPSPIPSVSISPGPTTDPF
VSIEGVANALRDACGTDPGLMCRTVYDLTHSNYLASGAEVFLGTPIKISLILLLAMVIRTLLHRFIRRTTERAASGRSTG
MLRGLRSNTLLGAFGDPTVLLERRRQRAGTVGSLLRSVTSIFVFGLAFLTILGELGLNLAPIVASAGVLGIAVGFGAQNL
VRDFLSGMFMLLEDQYGVGDVIDVGPVSGTVEAVSLRMTRLRDVEGTVWYVRNGEITRVGNKSQQWARTVLDVPLDYDTE
VAAAKRVLVRTADKLWKDEAWSGLILAEPEVWGMETMTADGYTLRIAIKTQPLKQWDVARELRERVRASLGRAGIELGTV
QRSEVVVVDDDDDDKPAEEEETPGGTGGSPGQGADDVPTPRIDPPAPARSGHSA

Sequences:

>Translated_454_residues
MSISRVPFGAVPFGGVPAEPVAAGLPPAVMGAEPSLLAQPVIPMLGAILSPTAAPTTAATVSPSPIPSVSISPGPTTDPF
VSIEGVANALRDACGTDPGLMCRTVYDLTHSNYLASGAEVFLGTPIKISLILLLAMVIRTLLHRFIRRTTERAASGRSTG
MLRGLRSNTLLGAFGDPTVLLERRRQRAGTVGSLLRSVTSIFVFGLAFLTILGELGLNLAPIVASAGVLGIAVGFGAQNL
VRDFLSGMFMLLEDQYGVGDVIDVGPVSGTVEAVSLRMTRLRDVEGTVWYVRNGEITRVGNKSQQWARTVLDVPLDYDTE
VAAAKRVLVRTADKLWKDEAWSGLILAEPEVWGMETMTADGYTLRIAIKTQPLKQWDVARELRERVRASLGRAGIELGTV
QRSEVVVVDDDDDDKPAEEEETPGGTGGSPGQGADDVPTPRIDPPAPARSGHSA
>Mature_453_residues
SISRVPFGAVPFGGVPAEPVAAGLPPAVMGAEPSLLAQPVIPMLGAILSPTAAPTTAATVSPSPIPSVSISPGPTTDPFV
SIEGVANALRDACGTDPGLMCRTVYDLTHSNYLASGAEVFLGTPIKISLILLLAMVIRTLLHRFIRRTTERAASGRSTGM
LRGLRSNTLLGAFGDPTVLLERRRQRAGTVGSLLRSVTSIFVFGLAFLTILGELGLNLAPIVASAGVLGIAVGFGAQNLV
RDFLSGMFMLLEDQYGVGDVIDVGPVSGTVEAVSLRMTRLRDVEGTVWYVRNGEITRVGNKSQQWARTVLDVPLDYDTEV
AAAKRVLVRTADKLWKDEAWSGLILAEPEVWGMETMTADGYTLRIAIKTQPLKQWDVARELRERVRASLGRAGIELGTVQ
RSEVVVVDDDDDDKPAEEEETPGGTGGSPGQGADDVPTPRIDPPAPARSGHSA

Specific function: May play a role in resistance to osmotic downshock [H]

COG id: COG0668

COG function: function code M; Small-conductance mechanosensitive channel

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mscS (TC 1.A.23) family [H]

Homologues:

Organism=Escherichia coli, GI87081787, Length=296, Percent_Identity=29.3918918918919, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010920
- InterPro:   IPR011066
- InterPro:   IPR006685
- InterPro:   IPR011014 [H]

Pfam domain/function: PF00924 MS_channel [H]

EC number: NA

Molecular weight: Translated: 48037; Mature: 47906

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSISRVPFGAVPFGGVPAEPVAAGLPPAVMGAEPSLLAQPVIPMLGAILSPTAAPTTAAT
CCCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
VSPSPIPSVSISPGPTTDPFVSIEGVANALRDACGTDPGLMCRTVYDLTHSNYLASGAEV
CCCCCCCCEECCCCCCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCCE
FLGTPIKISLILLLAMVIRTLLHRFIRRTTERAASGRSTGMLRGLRSNTLLGAFGDPTVL
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCHHHH
LERRRQRAGTVGSLLRSVTSIFVFGLAFLTILGELGLNLAPIVASAGVLGIAVGFGAQNL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCHHHH
VRDFLSGMFMLLEDQYGVGDVIDVGPVSGTVEAVSLRMTRLRDVEGTVWYVRNGEITRVG
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCEEEECC
NKSQQWARTVLDVPLDYDTEVAAAKRVLVRTADKLWKDEAWSGLILAEPEVWGMETMTAD
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEECC
GYTLRIAIKTQPLKQWDVARELRERVRASLGRAGIELGTVQRSEVVVVDDDDDDKPAEEE
CEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCCCCCCCCC
ETPGGTGGSPGQGADDVPTPRIDPPAPARSGHSA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SISRVPFGAVPFGGVPAEPVAAGLPPAVMGAEPSLLAQPVIPMLGAILSPTAAPTTAAT
CCCCCCCCCCCCCCCCCCCHHCCCCHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCC
VSPSPIPSVSISPGPTTDPFVSIEGVANALRDACGTDPGLMCRTVYDLTHSNYLASGAEV
CCCCCCCCEECCCCCCCCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHCCCCCE
FLGTPIKISLILLLAMVIRTLLHRFIRRTTERAASGRSTGMLRGLRSNTLLGAFGDPTVL
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEECCCCHHHH
LERRRQRAGTVGSLLRSVTSIFVFGLAFLTILGELGLNLAPIVASAGVLGIAVGFGAQNL
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCHHHHHHHCCHHHH
VRDFLSGMFMLLEDQYGVGDVIDVGPVSGTVEAVSLRMTRLRDVEGTVWYVRNGEITRVG
HHHHHHHHHHHHHCCCCCCCEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEECCEEEECC
NKSQQWARTVLDVPLDYDTEVAAAKRVLVRTADKLWKDEAWSGLILAEPEVWGMETMTAD
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCEEEECC
GYTLRIAIKTQPLKQWDVARELRERVRASLGRAGIELGTVQRSEVVVVDDDDDDKPAEEE
CEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCEECCCCCCEEEEEECCCCCCCCCCC
ETPGGTGGSPGQGADDVPTPRIDPPAPARSGHSA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]