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The map label for this gene is ruvC

Identifier: 158316902

GI number: 158316902

Start: 6168046

End: 6168582

Strand: Reverse

Name: ruvC

Synonym: Franean1_5146

Alternate gene names: 158316902

Gene position: 6168582-6168046 (Counterclockwise)

Preceding gene: 158316903

Following gene: 158316901

Centisome position: 68.68

GC content: 77.47

Gene sequence:

>537_bases
GTGCGTGTTCTCGGAGTCGACCCGGGGCTGACCCGCTGCGGCCTCGGGGTGGTCGACGGCGGCCCCGGCCGCCGGGCCAG
CCTGGTCGAGGTCGGCGTGGTGCGCACGCCCGCCTCGGACGAGGTGGCCGACCGGCTGCGGGCCGTCTCCGAGGGCGTGG
ACGAGTGGCTGGACCGGGTCCGCCCGGACGCGGTCGCGGTCGAGAAGGTTTTCAGCCAGGCCAACGTGCGCACGGTGATG
GGCACCGCGCAGGCCGGCGCGGTGGCCATCGTCGCCGCGGCCCGGCGCGGGCTGCCGATCGGTCTGTACACGCCGAGCGA
GGTCAAGGCCGCCGTCACCGGCAGCGGGCGCGCGGACAAGGCCCAGGTGGGGTTCATGGTGACGAAGCTGCTGGATCTTC
CGGAGGCGCCGCGCCCGGCGGATGCCGCCGACGCGCTCGCCCTGGCCCTGTGCCACCTGTGGCGCGGGCCGGCACTGGCC
CGGATGCGCGCCGCGACCCCCGCGCGGAGCCCGGGCGTGCCGGGTGGCCGGCGATGA

Upstream 100 bases:

>100_bases
GTACTGCCGGGCGGCCGCCTGTTCGGCGTGTCGTGGATGTCGGTGTTGCCCCGGCCACTAGGATCGAACGGATGTTCGTG
AGTGTGGTCGGGAGGGCTCG

Downstream 100 bases:

>100_bases
TCGCGTCGGTCAGCGGCACGGTGGAGGTGCTCTCGCCCGGCTCGGCGGTCGTCGACGTCGGTGGCGTCGGCGTCCTGGTG
TGGTGTACGCCGTCGACGCT

Product: Holliday junction resolvase

Products: NA

Alternate protein names: Holliday junction nuclease ruvC; Holliday junction resolvase ruvC

Number of amino acids: Translated: 178; Mature: 178

Protein sequence:

>178_residues
MRVLGVDPGLTRCGLGVVDGGPGRRASLVEVGVVRTPASDEVADRLRAVSEGVDEWLDRVRPDAVAVEKVFSQANVRTVM
GTAQAGAVAIVAAARRGLPIGLYTPSEVKAAVTGSGRADKAQVGFMVTKLLDLPEAPRPADAADALALALCHLWRGPALA
RMRAATPARSPGVPGGRR

Sequences:

>Translated_178_residues
MRVLGVDPGLTRCGLGVVDGGPGRRASLVEVGVVRTPASDEVADRLRAVSEGVDEWLDRVRPDAVAVEKVFSQANVRTVM
GTAQAGAVAIVAAARRGLPIGLYTPSEVKAAVTGSGRADKAQVGFMVTKLLDLPEAPRPADAADALALALCHLWRGPALA
RMRAATPARSPGVPGGRR
>Mature_178_residues
MRVLGVDPGLTRCGLGVVDGGPGRRASLVEVGVVRTPASDEVADRLRAVSEGVDEWLDRVRPDAVAVEKVFSQANVRTVM
GTAQAGAVAIVAAARRGLPIGLYTPSEVKAAVTGSGRADKAQVGFMVTKLLDLPEAPRPADAADALALALCHLWRGPALA
RMRAATPARSPGVPGGRR

Specific function: Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leav

COG id: COG0817

COG function: function code L; Holliday junction resolvasome, endonuclease subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvC family

Homologues:

Organism=Escherichia coli, GI1788170, Length=136, Percent_Identity=39.7058823529412, Blast_Score=94, Evalue=7e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVC_FRASN (A8KZE8)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001509410.1
- ProteinModelPortal:   A8KZE8
- SMR:   A8KZE8
- GeneID:   5673480
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_5146
- HOGENOM:   HBG437552
- OMA:   RTGWGVI
- ProtClustDB:   PRK00039
- BioCyc:   FSP1855:FRANEAN1_5146-MONOMER
- HAMAP:   MF_00034
- InterPro:   IPR012337
- InterPro:   IPR020563
- InterPro:   IPR002176
- PRINTS:   PR00696
- TIGRFAMs:   TIGR00228

Pfam domain/function: PF02075 RuvC; SSF53098 RNaseH_fold

EC number: =3.1.22.4

Molecular weight: Translated: 18391; Mature: 18391

Theoretical pI: Translated: 10.74; Mature: 10.74

Prosite motif: PS01321 RUVC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGVDPGLTRCGLGVVDGGPGRRASLVEVGVVRTPASDEVADRLRAVSEGVDEWLDRV
CEEECCCCCCHHCCCCCEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RPDAVAVEKVFSQANVRTVMGTAQAGAVAIVAAARRGLPIGLYTPSEVKAAVTGSGRADK
CCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCCCEEEEECHHHHEEEECCCCCCCH
AQVGFMVTKLLDLPEAPRPADAADALALALCHLWRGPALARMRAATPARSPGVPGGRR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRVLGVDPGLTRCGLGVVDGGPGRRASLVEVGVVRTPASDEVADRLRAVSEGVDEWLDRV
CEEECCCCCCHHCCCCCEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHH
RPDAVAVEKVFSQANVRTVMGTAQAGAVAIVAAARRGLPIGLYTPSEVKAAVTGSGRADK
CCHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHCCCEEEEECHHHHEEEECCCCCCCH
AQVGFMVTKLLDLPEAPRPADAADALALALCHLWRGPALARMRAATPARSPGVPGGRR
HHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA