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The map label for this gene is mhpF [C]

Identifier: 158316509

GI number: 158316509

Start: 5665819

End: 5666745

Strand: Reverse

Name: mhpF [C]

Synonym: Franean1_4744

Alternate gene names: 158316509

Gene position: 5666745-5665819 (Counterclockwise)

Preceding gene: 158316510

Following gene: 158316508

Centisome position: 63.09

GC content: 71.09

Gene sequence:

>927_bases
GTGCAGCAGGTGGCGATCATCGGGTCGGGGAACATCGGCACCGACCTCCTGATCAAGATCAAGCGAAGGTCCGAGTCGCT
GAGCGTGGCGGCCATGGTGGGGATCGACCCGGAGTCCGACGGCCTCGCCCGCGCCAGGCGGCTGGGCGTCGCCACGACGT
CCGACGGGGTGGCCGGTCTCCTGGCGATGCCCGAGTTCGAACAGGCCGGCATCGTGCTCGACGCGACGAGCGCCAACGCG
CACCGGGCGAACGCCGCGGCGCTGGCCCCGTACGGCCGGCGGCTGATCGACCTCACCCCGGCGGCGCTCGGGCCGTTCGT
GGTGCCCGCGGTCAACCTCGACGAGCACCTGAGCGCCCCCAACGTCAACATGACGACCTGCGGCGGGCAGGCCACCGTCC
CGATCGTCGCGGCGATCTCACGCGTCACCCCGGTGGCCTACGCGGAGATCGTCGCCACGGTGGCGTCGAAGTCCGCCGGG
CCCGGCACCCGCGCCAACATCGACGAGTTCACCGAGACGACGGCGCACGCGCTGGAGTCGGTGGGCGGCGCGCGGCGCGG
CAAGGCCATCATCATCCTGAACCCGGCCGAGCCGCCGCTCATCATGCGGGACACCGTGCTCTGCCTGGTCGGCGACGTCG
ACCGGGACGCGGTCACCGAATCGATCCACCGGATGATCGCGGACGTCGCCGCCTACGTGCCCGGCTACCGCCTGAAGCAG
GACGTGCAGTTCACTCCCGTGGACCCGGCCGAGATGCGCATTCTCCTGCCGGACGACACGGTCGACGTCCGCTGGAAGGT
GAGCGTGTTCCTCGAGGTGGAGGGCGCCGCTCATTATCTGCCGGCCTACGCCGGCAACCTGGACATCATGACGTCGGCGG
CCGTGCGGGTCGCCGAGCGCATCGCTGGAGCCGAGGTGACGGCATGA

Upstream 100 bases:

>100_bases
CTCGGTCCGCTGGCCCCCATCGAGCCCGGCGACGTGATCCAAGCCGAGGTCGGCCCCCTGGGCCCGGTAACGGCGACGTT
CGAGAAGGAAGGCTGAAACC

Downstream 100 bases:

>100_bases
GCGGGCCGAACATCTATCTGCAGGACGTCACCCTGCGGGACGGCATGCACGCCATCCGGCACCGGGTCGACCCGGAGCGG
GTCGGCGCCATCGTGGCCGC

Product: acetaldehyde dehydrogenase

Products: NA

Alternate protein names: Acetaldehyde dehydrogenase [acetylating] 2

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MQQVAIIGSGNIGTDLLIKIKRRSESLSVAAMVGIDPESDGLARARRLGVATTSDGVAGLLAMPEFEQAGIVLDATSANA
HRANAAALAPYGRRLIDLTPAALGPFVVPAVNLDEHLSAPNVNMTTCGGQATVPIVAAISRVTPVAYAEIVATVASKSAG
PGTRANIDEFTETTAHALESVGGARRGKAIIILNPAEPPLIMRDTVLCLVGDVDRDAVTESIHRMIADVAAYVPGYRLKQ
DVQFTPVDPAEMRILLPDDTVDVRWKVSVFLEVEGAAHYLPAYAGNLDIMTSAAVRVAERIAGAEVTA

Sequences:

>Translated_308_residues
MQQVAIIGSGNIGTDLLIKIKRRSESLSVAAMVGIDPESDGLARARRLGVATTSDGVAGLLAMPEFEQAGIVLDATSANA
HRANAAALAPYGRRLIDLTPAALGPFVVPAVNLDEHLSAPNVNMTTCGGQATVPIVAAISRVTPVAYAEIVATVASKSAG
PGTRANIDEFTETTAHALESVGGARRGKAIIILNPAEPPLIMRDTVLCLVGDVDRDAVTESIHRMIADVAAYVPGYRLKQ
DVQFTPVDPAEMRILLPDDTVDVRWKVSVFLEVEGAAHYLPAYAGNLDIMTSAAVRVAERIAGAEVTA
>Mature_308_residues
MQQVAIIGSGNIGTDLLIKIKRRSESLSVAAMVGIDPESDGLARARRLGVATTSDGVAGLLAMPEFEQAGIVLDATSANA
HRANAAALAPYGRRLIDLTPAALGPFVVPAVNLDEHLSAPNVNMTTCGGQATVPIVAAISRVTPVAYAEIVATVASKSAG
PGTRANIDEFTETTAHALESVGGARRGKAIIILNPAEPPLIMRDTVLCLVGDVDRDAVTESIHRMIADVAAYVPGYRLKQ
DVQFTPVDPAEMRILLPDDTVDVRWKVSVFLEVEGAAHYLPAYAGNLDIMTSAAVRVAERIAGAEVTA

Specific function: Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta- cleavage pathway for the degradation of aromatic compounds

COG id: COG4569

COG function: function code Q; Acetaldehyde dehydrogenase (acetylating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetaldehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1786547, Length=303, Percent_Identity=64.6864686468647, Blast_Score=374, Evalue=1e-105,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDH2_FRASN (A8LEP9)

Other databases:

- EMBL:   CP000820
- RefSeq:   YP_001509017.1
- ProteinModelPortal:   A8LEP9
- SMR:   A8LEP9
- GeneID:   5673086
- GenomeReviews:   CP000820_GR
- KEGG:   fre:Franean1_4744
- HOGENOM:   HBG300125
- OMA:   ANAHRAN
- ProtClustDB:   PRK08300
- BioCyc:   FSP1855:FRANEAN1_4744-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01657
- InterPro:   IPR003361
- InterPro:   IPR015426
- InterPro:   IPR016040
- InterPro:   IPR000534
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR21123
- PIRSF:   PIRSF015689
- SMART:   SM00859
- TIGRFAMs:   TIGR03215

Pfam domain/function: PF09290 AcetDehyd-dimer; PF01118 Semialdhyde_dh

EC number: =1.2.1.10

Molecular weight: Translated: 32221; Mature: 32221

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: BINDING 286-286

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQVAIIGSGNIGTDLLIKIKRRSESLSVAAMVGIDPESDGLARARRLGVATTSDGVAGL
CCEEEEEECCCCCCEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCEECCCCCEEE
LAMPEFEQAGIVLDATSANAHRANAAALAPYGRRLIDLTPAALGPFVVPAVNLDEHLSAP
EECCCCCCCCEEEEECCCCCCCCCCEEECCCCCEEEEECCHHHCCEEEEECCHHHHCCCC
NVNMTTCGGQATVPIVAAISRVTPVAYAEIVATVASKSAGPGTRANIDEFTETTAHALES
CCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VGGARRGKAIIILNPAEPPLIMRDTVLCLVGDVDRDAVTESIHRMIADVAAYVPGYRLKQ
HCCCCCCCEEEEECCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
DVQFTPVDPAEMRILLPDDTVDVRWKVSVFLEVEGAAHYLPAYAGNLDIMTSAAVRVAER
CCEECCCCHHHEEEECCCCCEEEEEEEEEEEEECCCCEECCHHCCCCHHHHHHHHHHHHH
IAGAEVTA
HCCCCCCC
>Mature Secondary Structure
MQQVAIIGSGNIGTDLLIKIKRRSESLSVAAMVGIDPESDGLARARRLGVATTSDGVAGL
CCEEEEEECCCCCCEEEEEEECCCCCEEEEEEEECCCCCCHHHHHHHHCCEECCCCCEEE
LAMPEFEQAGIVLDATSANAHRANAAALAPYGRRLIDLTPAALGPFVVPAVNLDEHLSAP
EECCCCCCCCEEEEECCCCCCCCCCEEECCCCCEEEEECCHHHCCEEEEECCHHHHCCCC
NVNMTTCGGQATVPIVAAISRVTPVAYAEIVATVASKSAGPGTRANIDEFTETTAHALES
CCEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHH
VGGARRGKAIIILNPAEPPLIMRDTVLCLVGDVDRDAVTESIHRMIADVAAYVPGYRLKQ
HCCCCCCCEEEEECCCCCCEEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
DVQFTPVDPAEMRILLPDDTVDVRWKVSVFLEVEGAAHYLPAYAGNLDIMTSAAVRVAER
CCEECCCCHHHEEEECCCCCEEEEEEEEEEEEECCCCEECCHHCCCCHHHHHHHHHHHHH
IAGAEVTA
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA