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The map label for this gene is fadE25 [H]

Identifier: 158316352

GI number: 158316352

Start: 5463109

End: 5464293

Strand: Reverse

Name: fadE25 [H]

Synonym: Franean1_4581

Alternate gene names: 158316352

Gene position: 5464293-5463109 (Counterclockwise)

Preceding gene: 158316353

Following gene: 158316351

Centisome position: 60.84

GC content: 74.09

Gene sequence:

>1185_bases
ATGCGGTTGGAGACCAGTCCGGACCTGGTGGAGTTCCGGGCCGAGGTTCGCGCGTTCATCGCCGAACACGGCCCGGGACC
GCGCCGGCGCACGGGGGTCCGCGCGCCCGAACCGGAGGAGATGCCCGGCCTGCGGGCCTGGATCGGCAGGCTCTACGCCG
CCGGCTACCTGGGCCAGGCCTGGCCCGTCGAGTACGGCGGCCGGCCGGGGGCCCGCCCGGAGCACGGGTTCATCGTCGCG
GAGGAGCTCGCGCGGGCCCGCACCTGGGGCGAGGTCGGCGCCGCCGCGCTCGCGGCCGGAGCGCTGATTGGGTTCGGCAG
CGAGGAGCAGAAGCGACGCTTCCTGCCGCGGATCCGGACCGCCGAGGACCTGTGGTGCCAGCTGTTCAGCGAACCGGGCG
CGGGCAGCGACCTCGCCGCCCTGTCCACCCGGGCGCGCCTGGACGGCGACCACTACGTCGTCGACGGGCAGAAGGTGTGG
ACGACGAACGGCCACCACGCCGACCTGGGCTACCTGCTGGCGCGCACGAGCACGGACGGCCCCAAGCAGGCCGGCATCAC
GGCGTTCGCGATGGACATGCGCAGCCCGGGCGTCGACATCCGCCCGCTGCGCGAGATCACCGGCACCAACGACTTCAACG
AGGTGTTCCTCGACGGCGTGCGGATCCCGGTCGAGCGGGTGATCGGCCGGGTCGACGACGGCTGGCGGGTCGCCAACCTG
AGTCTCGGCCATGAACGCAGCGGTGTGGGCGCCCGGGGGGTCGAGCTGTTCGGCCAGCTCGACGACCTGTTCGCGCTCGC
CGGGCAGGCCACCGTCGGCGGCGGGCCCGCCCTGGCGGACGGCGCGACCCGCCAGCGGCTCGGCCGGCTCGCGACCCGCG
TCCACGTGGCCGACAAGATGAGCAAGGCGGTGCAGTCGCGCATGGTCAACCGCACCGAGGACCCCGCGGACGCGCCGCTG
GCCAAGGTGTTCTACAGCGAGGTCAACCTGGAGGCGGCCGAGACCGGCGTCGCCCTGCAGGGCATCGGCGGCCTCGGCGT
GGACGAGGACGCCCCCTGGGCGGACGGCTGGTGGCAGGACGCCTTCCTCTACGCCCGCGCCTACACGATCGCGGGCGGCG
CGAACGAGGTGCTCAGGACGATTGTCGCCGAGCGGGCGCTGGGACTGCCGAGGGACAAGCGTTGA

Upstream 100 bases:

>100_bases
GCACCCGCGAGATCCAGCTCAACACGCTCGCCGAGCAGGTGCTCGGACTTCCGTACGACCCGGCGATGCCGCCGCGCTGA
CCGACGTTTAGGGAGACTCC

Downstream 100 bases:

>100_bases
CCACGGGCGAGATCGGCGTCGCGGTCGAACCGGAGGGTCGGCGGTACGGCATGCCGTGGCGCGGAGCGGACGCCGCGCGG
GCGGCCGAGCAGGCCGGCAT

Product: acyl-CoA dehydrogenase domain-containing protein

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRLETSPDLVEFRAEVRAFIAEHGPGPRRRTGVRAPEPEEMPGLRAWIGRLYAAGYLGQAWPVEYGGRPGARPEHGFIVA
EELARARTWGEVGAAALAAGALIGFGSEEQKRRFLPRIRTAEDLWCQLFSEPGAGSDLAALSTRARLDGDHYVVDGQKVW
TTNGHHADLGYLLARTSTDGPKQAGITAFAMDMRSPGVDIRPLREITGTNDFNEVFLDGVRIPVERVIGRVDDGWRVANL
SLGHERSGVGARGVELFGQLDDLFALAGQATVGGGPALADGATRQRLGRLATRVHVADKMSKAVQSRMVNRTEDPADAPL
AKVFYSEVNLEAAETGVALQGIGGLGVDEDAPWADGWWQDAFLYARAYTIAGGANEVLRTIVAERALGLPRDKR

Sequences:

>Translated_394_residues
MRLETSPDLVEFRAEVRAFIAEHGPGPRRRTGVRAPEPEEMPGLRAWIGRLYAAGYLGQAWPVEYGGRPGARPEHGFIVA
EELARARTWGEVGAAALAAGALIGFGSEEQKRRFLPRIRTAEDLWCQLFSEPGAGSDLAALSTRARLDGDHYVVDGQKVW
TTNGHHADLGYLLARTSTDGPKQAGITAFAMDMRSPGVDIRPLREITGTNDFNEVFLDGVRIPVERVIGRVDDGWRVANL
SLGHERSGVGARGVELFGQLDDLFALAGQATVGGGPALADGATRQRLGRLATRVHVADKMSKAVQSRMVNRTEDPADAPL
AKVFYSEVNLEAAETGVALQGIGGLGVDEDAPWADGWWQDAFLYARAYTIAGGANEVLRTIVAERALGLPRDKR
>Mature_394_residues
MRLETSPDLVEFRAEVRAFIAEHGPGPRRRTGVRAPEPEEMPGLRAWIGRLYAAGYLGQAWPVEYGGRPGARPEHGFIVA
EELARARTWGEVGAAALAAGALIGFGSEEQKRRFLPRIRTAEDLWCQLFSEPGAGSDLAALSTRARLDGDHYVVDGQKVW
TTNGHHADLGYLLARTSTDGPKQAGITAFAMDMRSPGVDIRPLREITGTNDFNEVFLDGVRIPVERVIGRVDDGWRVANL
SLGHERSGVGARGVELFGQLDDLFALAGQATVGGGPALADGATRQRLGRLATRVHVADKMSKAVQSRMVNRTEDPADAPL
AKVFYSEVNLEAAETGVALQGIGGLGVDEDAPWADGWWQDAFLYARAYTIAGGANEVLRTIVAERALGLPRDKR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361497, Length=349, Percent_Identity=29.7994269340974, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI76496475, Length=361, Percent_Identity=28.5318559556787, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4557235, Length=361, Percent_Identity=28.5318559556787, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI226958412, Length=384, Percent_Identity=28.125, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI4557231, Length=344, Percent_Identity=28.4883720930233, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI187960098, Length=344, Percent_Identity=28.4883720930233, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI4501859, Length=350, Percent_Identity=28, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI226958414, Length=337, Percent_Identity=27.299703264095, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI4557233, Length=346, Percent_Identity=28.6127167630058, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI4501857, Length=295, Percent_Identity=26.1016949152542, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI7656849, Length=320, Percent_Identity=26.875, Blast_Score=94, Evalue=2e-19,
Organism=Escherichia coli, GI87081958, Length=342, Percent_Identity=25.7309941520468, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786223, Length=317, Percent_Identity=23.3438485804416, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17570075, Length=399, Percent_Identity=27.8195488721804, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17569725, Length=344, Percent_Identity=27.0348837209302, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17508101, Length=406, Percent_Identity=26.6009852216749, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17534899, Length=352, Percent_Identity=28.125, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17538396, Length=366, Percent_Identity=31.4207650273224, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=319, Percent_Identity=27.2727272727273, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI32563615, Length=205, Percent_Identity=32.1951219512195, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI71985184, Length=379, Percent_Identity=27.4406332453826, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71985192, Length=239, Percent_Identity=30.9623430962343, Blast_Score=92, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI71990804, Length=214, Percent_Identity=29.9065420560748, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17533517, Length=347, Percent_Identity=23.6311239193084, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551932, Length=176, Percent_Identity=31.8181818181818, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17505929, Length=183, Percent_Identity=30.6010928961749, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71982178, Length=170, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24646207, Length=329, Percent_Identity=31.306990881459, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI281363737, Length=351, Percent_Identity=27.0655270655271, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21355753, Length=220, Percent_Identity=32.2727272727273, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24666513, Length=342, Percent_Identity=27.1929824561404, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI24660351, Length=313, Percent_Identity=27.7955271565495, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21356377, Length=337, Percent_Identity=27.0029673590504, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42570; Mature: 42570

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLETSPDLVEFRAEVRAFIAEHGPGPRRRTGVRAPEPEEMPGLRAWIGRLYAAGYLGQA
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
WPVEYGGRPGARPEHGFIVAEELARARTWGEVGAAALAAGALIGFGSEEQKRRFLPRIRT
CCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
AEDLWCQLFSEPGAGSDLAALSTRARLDGDHYVVDGQKVWTTNGHHADLGYLLARTSTDG
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEECCCEEEECCCCCCCHHHEEEECCCCC
PKQAGITAFAMDMRSPGVDIRPLREITGTNDFNEVFLDGVRIPVERVIGRVDDGWRVANL
CHHHCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHHHCCCCCCHHHHHCCCCCCEEEEEE
SLGHERSGVGARGVELFGQLDDLFALAGQATVGGGPALADGATRQRLGRLATRVHVADKM
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHH
SKAVQSRMVNRTEDPADAPLAKVFYSEVNLEAAETGVALQGIGGLGVDEDAPWADGWWQD
HHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCCCCCCCHHH
AFLYARAYTIAGGANEVLRTIVAERALGLPRDKR
HHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRLETSPDLVEFRAEVRAFIAEHGPGPRRRTGVRAPEPEEMPGLRAWIGRLYAAGYLGQA
CCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
WPVEYGGRPGARPEHGFIVAEELARARTWGEVGAAALAAGALIGFGSEEQKRRFLPRIRT
CCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCC
AEDLWCQLFSEPGAGSDLAALSTRARLDGDHYVVDGQKVWTTNGHHADLGYLLARTSTDG
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEEECCCEEEECCCCCCCHHHEEEECCCCC
PKQAGITAFAMDMRSPGVDIRPLREITGTNDFNEVFLDGVRIPVERVIGRVDDGWRVANL
CHHHCCEEEEEECCCCCCCCHHHHHHCCCCCHHHHHHCCCCCCHHHHHCCCCCCEEEEEE
SLGHERSGVGARGVELFGQLDDLFALAGQATVGGGPALADGATRQRLGRLATRVHVADKM
ECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHH
SKAVQSRMVNRTEDPADAPLAKVFYSEVNLEAAETGVALQGIGGLGVDEDAPWADGWWQD
HHHHHHHHHCCCCCCCCCHHHHHHHHHCCCHHHHCCEEEECCCCCCCCCCCCCCCCCHHH
AFLYARAYTIAGGANEVLRTIVAERALGLPRDKR
HHHHHHHHEECCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]