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The map label for this gene is uxaC [H]

Identifier: 158315003

GI number: 158315003

Start: 3775791

End: 3777266

Strand: Direct

Name: uxaC [H]

Synonym: Franean1_3197

Alternate gene names: 158315003

Gene position: 3775791-3777266 (Clockwise)

Preceding gene: 158315001

Following gene: 158315004

Centisome position: 42.04

GC content: 71.48

Gene sequence:

>1476_bases
GTGGCAGGCAAGTTCGCTGGTGCAGGCAACTCCGCCGTGTCAGGTGGCGTCACCGTGCCGGGTGGTGGTGTCCCGCTCCG
CCCGCATCCCGACCGCCTGTTCCCGGTCGACCTGGGGGTGCGGGCGCTCGCCCGGCGGCTGTACGAAGCCGTGCGTGACC
TGCCAATCCTTTCCCCGCACGGTCACGTCGACCCCTTCTTGCTGGTACACGACGAGGCGTTCGCGGACCCGGCCAGCCTG
CTGATCACTCCGGACCATTACGTGACCCGGCTGCTGCACGCCAGCGGGGTGCCGCTGGCGGAGCTGGGCGTCGGACGCGG
CCCGCTGCCCGAGGAACAGGCGCGAGCGGTGTGGCGCACGTTCTGCGAGCACTGGGCCGTGTTCCGCGGCACCCCGGTGC
GTTACTGGCTGGAATCCCAGCTGGCCGAGATCTTCGGTGTCACCGAACGGCCCGGTCCCGACAGCGCGGACCGGATCTAC
GACCAGGTCGCCGAGCGGCTCGCCGACGAGGCGTATCGACCTCGAGCGCTGTTCCGCCGGTTCGACATCGAGGTTCTGGC
CACCACCGACGACCCCTGCAGCGATCTCGCGGCACACCGCGCTCTCACCGCGGATCCGGACTGGCCCGGCCGGGTCATCC
CCACCTTCCGCCCCGACCGGTACCTGGAGCCCACCCGAGCGGGCTGGGACGAGGCGGTGCGGCGTCTCGGCGAGGCGGCC
GACGCCGACGTCGGTGATTACGACGGCTACGTGCGCGCGCTGGAGGCCCGTCGCCGCTACTTCGCCGAGCACGGTGCCAC
GTCCTGCGACCACAGCCATCCGGATGTCCGGACCGATCCGCTGCCGCACGCCGAGGCCGCCAGGATCTTCCGCGCCGCTC
TGGCCGGGGAGGCGAGCGAGGCCGAGGCCACCGCGTTCCGCCGGCACATGATCTGCGAGTCGGCGCGGATGTCCTGCGAG
GACGGGCTGGTGATGACGCTGCATCCGAGCGTCCGGCGCAACCACCACACCCCGACCCTGCGCCGGTACGGCCCGGACAC
CGGGCACGACATCCCGCTGCGAACCGAGTTTACTCAGGCGCTGCAGCCGCTCCTCGATCGTCACGGCACCGATCCCGACT
TCCGCCTGGTGCTGTTCACCCTCGACGAGACGGTCTTCTCGCGGGAGATCGCCCCACTCGCGGGCTTCTACCCGGCGGTG
TACGTCGGCGCTCCCTGGTGGTTCCTCGACGCGCCGGACTCCATCCGCCGCTTCCGGCGGGCGGTGACCGAGACCGCGGG
TTTCACGCGCACCTCCGGCTTCGTGGACGACACGCGTGCCTTCTGCTCCGTGCCGGTCCGCCACGACATGTCCCGTCGGC
TCGACTGCGGCGTGCTCGCCGAGCTCGTCGCCGAGCACCGGCTGGAGGAGGACGAGGCCTTCGAGACCGCCGTCGAGCTG
GTGGCGGTCAGGCCGCGAGAGGCCTTCCGTCTGTGA

Upstream 100 bases:

>100_bases
ACGGCGCGGACAACTTGTGGCAACCGGTTGCCGTCGGGTCGCCGCACCGTCGACGCTCCACACTGTGTCAGGCAACCCCG
CCCTGTCAGGTAACTCCAAC

Downstream 100 bases:

>100_bases
ACCATTCCGCGGCCGTGCCTGTGAACCGCCCAGTGGCGGCGCCCGCCAGCGGCCCCGTGGCCCCGTCGCCGAGTCGTCCT
GCGGCTGTCGCTCGACCGCT

Product: glucuronate isomerase

Products: NA

Alternate protein names: Glucuronate isomerase; Uronic isomerase [H]

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MAGKFAGAGNSAVSGGVTVPGGGVPLRPHPDRLFPVDLGVRALARRLYEAVRDLPILSPHGHVDPFLLVHDEAFADPASL
LITPDHYVTRLLHASGVPLAELGVGRGPLPEEQARAVWRTFCEHWAVFRGTPVRYWLESQLAEIFGVTERPGPDSADRIY
DQVAERLADEAYRPRALFRRFDIEVLATTDDPCSDLAAHRALTADPDWPGRVIPTFRPDRYLEPTRAGWDEAVRRLGEAA
DADVGDYDGYVRALEARRRYFAEHGATSCDHSHPDVRTDPLPHAEAARIFRAALAGEASEAEATAFRRHMICESARMSCE
DGLVMTLHPSVRRNHHTPTLRRYGPDTGHDIPLRTEFTQALQPLLDRHGTDPDFRLVLFTLDETVFSREIAPLAGFYPAV
YVGAPWWFLDAPDSIRRFRRAVTETAGFTRTSGFVDDTRAFCSVPVRHDMSRRLDCGVLAELVAEHRLEEDEAFETAVEL
VAVRPREAFRL

Sequences:

>Translated_491_residues
MAGKFAGAGNSAVSGGVTVPGGGVPLRPHPDRLFPVDLGVRALARRLYEAVRDLPILSPHGHVDPFLLVHDEAFADPASL
LITPDHYVTRLLHASGVPLAELGVGRGPLPEEQARAVWRTFCEHWAVFRGTPVRYWLESQLAEIFGVTERPGPDSADRIY
DQVAERLADEAYRPRALFRRFDIEVLATTDDPCSDLAAHRALTADPDWPGRVIPTFRPDRYLEPTRAGWDEAVRRLGEAA
DADVGDYDGYVRALEARRRYFAEHGATSCDHSHPDVRTDPLPHAEAARIFRAALAGEASEAEATAFRRHMICESARMSCE
DGLVMTLHPSVRRNHHTPTLRRYGPDTGHDIPLRTEFTQALQPLLDRHGTDPDFRLVLFTLDETVFSREIAPLAGFYPAV
YVGAPWWFLDAPDSIRRFRRAVTETAGFTRTSGFVDDTRAFCSVPVRHDMSRRLDCGVLAELVAEHRLEEDEAFETAVEL
VAVRPREAFRL
>Mature_490_residues
AGKFAGAGNSAVSGGVTVPGGGVPLRPHPDRLFPVDLGVRALARRLYEAVRDLPILSPHGHVDPFLLVHDEAFADPASLL
ITPDHYVTRLLHASGVPLAELGVGRGPLPEEQARAVWRTFCEHWAVFRGTPVRYWLESQLAEIFGVTERPGPDSADRIYD
QVAERLADEAYRPRALFRRFDIEVLATTDDPCSDLAAHRALTADPDWPGRVIPTFRPDRYLEPTRAGWDEAVRRLGEAAD
ADVGDYDGYVRALEARRRYFAEHGATSCDHSHPDVRTDPLPHAEAARIFRAALAGEASEAEATAFRRHMICESARMSCED
GLVMTLHPSVRRNHHTPTLRRYGPDTGHDIPLRTEFTQALQPLLDRHGTDPDFRLVLFTLDETVFSREIAPLAGFYPAVY
VGAPWWFLDAPDSIRRFRRAVTETAGFTRTSGFVDDTRAFCSVPVRHDMSRRLDCGVLAELVAEHRLEEDEAFETAVELV
AVRPREAFRL

Specific function: Hexuronate conversion to KDG. [C]

COG id: COG1904

COG function: function code G; Glucuronate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uronate isomerase family [H]

Homologues:

Organism=Escherichia coli, GI2367192, Length=430, Percent_Identity=27.2093023255814, Blast_Score=165, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003766
- InterPro:   IPR023177 [H]

Pfam domain/function: PF02614 UxaC [H]

EC number: =5.3.1.12 [H]

Molecular weight: Translated: 54815; Mature: 54684

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGKFAGAGNSAVSGGVTVPGGGVPLRPHPDRLFPVDLGVRALARRLYEAVRDLPILSPH
CCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCC
GHVDPFLLVHDEAFADPASLLITPDHYVTRLLHASGVPLAELGVGRGPLPEEQARAVWRT
CCCCCEEEEECHHHCCCCCEEECCHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHH
FCEHWAVFRGTPVRYWLESQLAEIFGVTERPGPDSADRIYDQVAERLADEAYRPRALFRR
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
FDIEVLATTDDPCSDLAAHRALTADPDWPGRVIPTFRPDRYLEPTRAGWDEAVRRLGEAA
HCEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
DADVGDYDGYVRALEARRRYFAEHGATSCDHSHPDVRTDPLPHAEAARIFRAALAGEASE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
AEATAFRRHMICESARMSCEDGLVMTLHPSVRRNHHTPTLRRYGPDTGHDIPLRTEFTQA
HHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHCCCCCCCHHHCCCCCCCCCCCHHHHHHH
LQPLLDRHGTDPDFRLVLFTLDETVFSREIAPLAGFYPAVYVGAPWWFLDAPDSIRRFRR
HHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHCCCCEEEECCCHHHHHHHH
AVTETAGFTRTSGFVDDTRAFCSVPVRHDMSRRLDCGVLAELVAEHRLEEDEAFETAVEL
HHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
VAVRPREAFRL
HHCCCHHHHCC
>Mature Secondary Structure 
AGKFAGAGNSAVSGGVTVPGGGVPLRPHPDRLFPVDLGVRALARRLYEAVRDLPILSPH
CCCCCCCCCCCCCCCEECCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCC
GHVDPFLLVHDEAFADPASLLITPDHYVTRLLHASGVPLAELGVGRGPLPEEQARAVWRT
CCCCCEEEEECHHHCCCCCEEECCHHHHHHHHHHCCCCHHHHCCCCCCCCHHHHHHHHHH
FCEHWAVFRGTPVRYWLESQLAEIFGVTERPGPDSADRIYDQVAERLADEAYRPRALFRR
HHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
FDIEVLATTDDPCSDLAAHRALTADPDWPGRVIPTFRPDRYLEPTRAGWDEAVRRLGEAA
HCEEEEEECCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
DADVGDYDGYVRALEARRRYFAEHGATSCDHSHPDVRTDPLPHAEAARIFRAALAGEASE
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCH
AEATAFRRHMICESARMSCEDGLVMTLHPSVRRNHHTPTLRRYGPDTGHDIPLRTEFTQA
HHHHHHHHHHHHHHHHCCCCCCEEEEECHHHHCCCCCCCHHHCCCCCCCCCCCHHHHHHH
LQPLLDRHGTDPDFRLVLFTLDETVFSREIAPLAGFYPAVYVGAPWWFLDAPDSIRRFRR
HHHHHHHCCCCCCCEEEEEEHHHHHHHHHHHHHHHCCCHHHCCCCEEEECCCHHHHHHHH
AVTETAGFTRTSGFVDDTRAFCSVPVRHDMSRRLDCGVLAELVAEHRLEEDEAFETAVEL
HHHHHCCCCCCCCCCHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHH
VAVRPREAFRL
HHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA