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The map label for this gene is uidA [H]

Identifier: 158315001

GI number: 158315001

Start: 3772552

End: 3774324

Strand: Direct

Name: uidA [H]

Synonym: Franean1_3195

Alternate gene names: 158315001

Gene position: 3772552-3774324 (Clockwise)

Preceding gene: 158315000

Following gene: 158315003

Centisome position: 42.0

GC content: 67.91

Gene sequence:

>1773_bases
ATGCTTCGTCCCCAGGACGGTTCGACACGGGAGCGGCGATCTCTGGGCGGGCTGTGGGCCTTCCGTCTCGACCCCGCGGG
TACCGGGCGGAACGCGGGCTGGTGGCGTGCGCGCCTGCCCGGGGCCCGGGAGATGCCGGTGCCGGCCAGCTACAACGACA
TCGTGCCCGATCTCGCCGTGCGTGATCATGTTGGTGACGCCTGGTACCAGACGGTCGTCCGCATCCCGGCCGGCTGGTCC
GCGCGGCGGGTGGTGCTGCGTTTCGACGCCGCGACCCACCGTGCGGTCGTCTGGGTGAACGACACGCTCGTCGCCGAGCA
CGAGGGTGGCTACACGCCGTTCGAAGCCGACATCACCGGGGTCGTGGCGCCCGGGGACGAGGCCCGGGTCACCGTGGTCG
TCAACAACGAGCTCACGTTGACCTCGATACCGCCCGGCATCGTGGAGGACACCGCGCAGGGACGCCGCCAGAAGTACTTC
CACGACTTCTTCAACTACGCGGGTCTGCACCGCTCGGTCTGGCTGTACACCACACCGCACACGCGGATCAGCGACATCGC
GGTGGAGACCGCTCTCGACGGCGCCGCGGGCACGGTGCGCTACGCGGTGGAGATCGAGGGTGCCCAGGGTGTTGCCGCCA
TCCGGGTCGTGCTCCGCGACGCGCAGGGGCGGGAGGTCGCCGCCGCCGACGGTGCCGTGGGAATGTTGAACGTGCCAGCC
GTGCATCCATGGGCACCGGGTGACGGTTACCTGTACGAGCTCGATGCCCGTCTGGTCGGTGCGGGCGGGGAGGTGGCCGA
CAGTTATGTCCTGCCGGTCGGTGTGCGTACCGTCGAGGTACGCGGCACCCAGTTTCTGATCAACGGGGAGCCTTTCTACT
TCCGGGGCTTCGGTAAGCACGAGGACGCGCCGGTGCGCGGCAAGGCCCATGACGACGCGCTCATGGTCCATGATTTCGAG
CTGATGGAGTGGATCGGCGCCAACTCCTTCCGCACCTCCCACTATCCGTATGCGGAGGAGGTACTGGAGTACGCCGACCG
GAGTGGCATCGTCGTGATCGACGAGACCGCGGCCGTCGGTCTGAACCTGAAGGCCTCGCTCGCTTTCGGCAGCAGGCCGA
CGGTGAGTACCTTCGGTGAGGATGGCATCAGCTCCGTCACCCAGCGCGCGCATCTCCAGGCCGTGCGGGAACTGATAATC
CGGGACCGGAACCATCCGAGTGTGGTGTTGTGGAGCCTCGCCAACGAGCCGGATTCCAGTACCGCCGCCGCCCGGGAGTA
CTTCGCGCCGCTGTTCGCCGAGGCCCGCAAGCTCGACCCGACCTGCCCGGTGGGCTTCGTCAACTCGTTCGACCAGTGCC
AGGTCACCGAGCTCGCCGACGTCGTCATGATCAACCGTTACTACGGCTGGTACATCAACAACGGGGAGCTCAAGGCCGCC
GAGGTCGCACTGGAGGCCGAGCTGAACAGGTGGGCCGCCCACGGCAAGCCGGTGATCGTCACCGAGTACGGAGCGGACAC
CATGGCCGGGCTGCACGCCGTGGTCGACACCCCCTGGTCCGAGGAGTACCAGGTGCGGTTCCTCGAGATGCACCACCGGG
TGTTCGACCGGGTGGATGCCGTGATCGGCGAGCACATCTGGAACTTCGCCGACTTCGCCACCAGCCCGCACATCATCCGG
GTCGACGGCAACAAGAAGGGCGTGTTCACCCGGGACCGGCACCCCAAGAGCGCCGCGTTCTCCGTCCGCCGGCGCTGGCG
CCCGCAGGCCTGA

Upstream 100 bases:

>100_bases
AGTGGCAACCGCTTGCTCGGCCCGTCCGTCGACAGCTGAATGTCTCCGTACACCGCGGAAACCGCGGCGTTGCCGCCGCA
TGTCTTCAGGGAGCCCAAGA

Downstream 100 bases:

>100_bases
GGCCGGCGCCGGCCGGTGGCGCCACGCCTCAGGCCGGGCGGCGAAGCCGGTACAGGACCTCCCCGGAGTGCGGCACGACC
AGCGTGTCCGGGTCGGCTGC

Product: beta-D-glucuronidase

Products: NA

Alternate protein names: GUS; Beta-D-glucuronoside glucuronosohydrolase [H]

Number of amino acids: Translated: 590; Mature: 590

Protein sequence:

>590_residues
MLRPQDGSTRERRSLGGLWAFRLDPAGTGRNAGWWRARLPGAREMPVPASYNDIVPDLAVRDHVGDAWYQTVVRIPAGWS
ARRVVLRFDAATHRAVVWVNDTLVAEHEGGYTPFEADITGVVAPGDEARVTVVVNNELTLTSIPPGIVEDTAQGRRQKYF
HDFFNYAGLHRSVWLYTTPHTRISDIAVETALDGAAGTVRYAVEIEGAQGVAAIRVVLRDAQGREVAAADGAVGMLNVPA
VHPWAPGDGYLYELDARLVGAGGEVADSYVLPVGVRTVEVRGTQFLINGEPFYFRGFGKHEDAPVRGKAHDDALMVHDFE
LMEWIGANSFRTSHYPYAEEVLEYADRSGIVVIDETAAVGLNLKASLAFGSRPTVSTFGEDGISSVTQRAHLQAVRELII
RDRNHPSVVLWSLANEPDSSTAAAREYFAPLFAEARKLDPTCPVGFVNSFDQCQVTELADVVMINRYYGWYINNGELKAA
EVALEAELNRWAAHGKPVIVTEYGADTMAGLHAVVDTPWSEEYQVRFLEMHHRVFDRVDAVIGEHIWNFADFATSPHIIR
VDGNKKGVFTRDRHPKSAAFSVRRRWRPQA

Sequences:

>Translated_590_residues
MLRPQDGSTRERRSLGGLWAFRLDPAGTGRNAGWWRARLPGAREMPVPASYNDIVPDLAVRDHVGDAWYQTVVRIPAGWS
ARRVVLRFDAATHRAVVWVNDTLVAEHEGGYTPFEADITGVVAPGDEARVTVVVNNELTLTSIPPGIVEDTAQGRRQKYF
HDFFNYAGLHRSVWLYTTPHTRISDIAVETALDGAAGTVRYAVEIEGAQGVAAIRVVLRDAQGREVAAADGAVGMLNVPA
VHPWAPGDGYLYELDARLVGAGGEVADSYVLPVGVRTVEVRGTQFLINGEPFYFRGFGKHEDAPVRGKAHDDALMVHDFE
LMEWIGANSFRTSHYPYAEEVLEYADRSGIVVIDETAAVGLNLKASLAFGSRPTVSTFGEDGISSVTQRAHLQAVRELII
RDRNHPSVVLWSLANEPDSSTAAAREYFAPLFAEARKLDPTCPVGFVNSFDQCQVTELADVVMINRYYGWYINNGELKAA
EVALEAELNRWAAHGKPVIVTEYGADTMAGLHAVVDTPWSEEYQVRFLEMHHRVFDRVDAVIGEHIWNFADFATSPHIIR
VDGNKKGVFTRDRHPKSAAFSVRRRWRPQA
>Mature_590_residues
MLRPQDGSTRERRSLGGLWAFRLDPAGTGRNAGWWRARLPGAREMPVPASYNDIVPDLAVRDHVGDAWYQTVVRIPAGWS
ARRVVLRFDAATHRAVVWVNDTLVAEHEGGYTPFEADITGVVAPGDEARVTVVVNNELTLTSIPPGIVEDTAQGRRQKYF
HDFFNYAGLHRSVWLYTTPHTRISDIAVETALDGAAGTVRYAVEIEGAQGVAAIRVVLRDAQGREVAAADGAVGMLNVPA
VHPWAPGDGYLYELDARLVGAGGEVADSYVLPVGVRTVEVRGTQFLINGEPFYFRGFGKHEDAPVRGKAHDDALMVHDFE
LMEWIGANSFRTSHYPYAEEVLEYADRSGIVVIDETAAVGLNLKASLAFGSRPTVSTFGEDGISSVTQRAHLQAVRELII
RDRNHPSVVLWSLANEPDSSTAAAREYFAPLFAEARKLDPTCPVGFVNSFDQCQVTELADVVMINRYYGWYINNGELKAA
EVALEAELNRWAAHGKPVIVTEYGADTMAGLHAVVDTPWSEEYQVRFLEMHHRVFDRVDAVIGEHIWNFADFATSPHIIR
VDGNKKGVFTRDRHPKSAAFSVRRRWRPQA

Specific function: Unknown

COG id: COG3250

COG function: function code G; Beta-galactosidase/beta-glucuronidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 2 family [H]

Homologues:

Organism=Homo sapiens, GI268834192, Length=618, Percent_Identity=44.1747572815534, Blast_Score=486, Evalue=1e-137,
Organism=Escherichia coli, GI1787903, Length=598, Percent_Identity=54.6822742474916, Blast_Score=644, Evalue=0.0,
Organism=Escherichia coli, GI48994920, Length=497, Percent_Identity=24.1448692152917, Blast_Score=113, Evalue=4e-26,
Organism=Escherichia coli, GI1786539, Length=483, Percent_Identity=25.4658385093168, Blast_Score=103, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17510825, Length=618, Percent_Identity=36.2459546925566, Blast_Score=366, Evalue=1e-101,
Organism=Drosophila melanogaster, GI62471735, Length=618, Percent_Identity=43.042071197411, Blast_Score=461, Evalue=1e-130,
Organism=Drosophila melanogaster, GI19922582, Length=618, Percent_Identity=43.042071197411, Blast_Score=461, Evalue=1e-130,
Organism=Drosophila melanogaster, GI24655438, Length=618, Percent_Identity=43.042071197411, Blast_Score=461, Evalue=1e-130,
Organism=Drosophila melanogaster, GI24651745, Length=624, Percent_Identity=41.5064102564103, Blast_Score=435, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008979
- InterPro:   IPR006101
- InterPro:   IPR013812
- InterPro:   IPR006104
- InterPro:   IPR006102
- InterPro:   IPR006103
- InterPro:   IPR017853
- InterPro:   IPR013781 [H]

Pfam domain/function: PF00703 Glyco_hydro_2; PF02836 Glyco_hydro_2_C; PF02837 Glyco_hydro_2_N [H]

EC number: =3.2.1.31 [H]

Molecular weight: Translated: 65295; Mature: 65295

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00719 GLYCOSYL_HYDROL_F2_1 ; PS00608 GLYCOSYL_HYDROL_F2_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRPQDGSTRERRSLGGLWAFRLDPAGTGRNAGWWRARLPGAREMPVPASYNDIVPDLAV
CCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCHHCCCCHHH
RDHVGDAWYQTVVRIPAGWSARRVVLRFDAATHRAVVWVNDTLVAEHEGGYTPFEADITG
HHCCCHHHHHHHEECCCCCCCEEEEEEEECCCCEEEEEEECEEEEECCCCCCCEECCEEE
VVAPGDEARVTVVVNNELTLTSIPPGIVEDTAQGRRQKYFHDFFNYAGLHRSVWLYTTPH
EECCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
TRISDIAVETALDGAAGTVRYAVEIEGAQGVAAIRVVLRDAQGREVAAADGAVGMLNVPA
CCHHHEEHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCEEEEECCE
VHPWAPGDGYLYELDARLVGAGGEVADSYVLPVGVRTVEVRGTQFLINGEPFYFRGFGKH
ECCCCCCCCEEEEEEEEEECCCCCCCCCEEEECCEEEEEEECEEEEECCCCEEEECCCCC
EDAPVRGKAHDDALMVHDFELMEWIGANSFRTSHYPYAEEVLEYADRSGIVVIDETAAVG
CCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCEEC
LNLKASLAFGSRPTVSTFGEDGISSVTQRAHLQAVRELIIRDRNHPSVVLWSLANEPDSS
CCEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
TAAAREYFAPLFAEARKLDPTCPVGFVNSFDQCQVTELADVVMINRYYGWYINNGELKAA
HHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHEEEEEEEEEEEEECCCEEEE
EVALEAELNRWAAHGKPVIVTEYGADTMAGLHAVVDTPWSEEYQVRFLEMHHRVFDRVDA
EEEHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VIGEHIWNFADFATSPHIIRVDGNKKGVFTRDRHPKSAAFSVRRRWRPQA
HHHHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MLRPQDGSTRERRSLGGLWAFRLDPAGTGRNAGWWRARLPGAREMPVPASYNDIVPDLAV
CCCCCCCCCHHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCHHCCCCHHH
RDHVGDAWYQTVVRIPAGWSARRVVLRFDAATHRAVVWVNDTLVAEHEGGYTPFEADITG
HHCCCHHHHHHHEECCCCCCCEEEEEEEECCCCEEEEEEECEEEEECCCCCCCEECCEEE
VVAPGDEARVTVVVNNELTLTSIPPGIVEDTAQGRRQKYFHDFFNYAGLHRSVWLYTTPH
EECCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCC
TRISDIAVETALDGAAGTVRYAVEIEGAQGVAAIRVVLRDAQGREVAAADGAVGMLNVPA
CCHHHEEHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCEEEEECCE
VHPWAPGDGYLYELDARLVGAGGEVADSYVLPVGVRTVEVRGTQFLINGEPFYFRGFGKH
ECCCCCCCCEEEEEEEEEECCCCCCCCCEEEECCEEEEEEECEEEEECCCCEEEECCCCC
EDAPVRGKAHDDALMVHDFELMEWIGANSFRTSHYPYAEEVLEYADRSGIVVIDETAAVG
CCCCCCCCCCCCEEEEEHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCEEC
LNLKASLAFGSRPTVSTFGEDGISSVTQRAHLQAVRELIIRDRNHPSVVLWSLANEPDSS
CCEEEEEECCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCC
TAAAREYFAPLFAEARKLDPTCPVGFVNSFDQCQVTELADVVMINRYYGWYINNGELKAA
HHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHEEEEEEEEEEEEECCCEEEE
EVALEAELNRWAAHGKPVIVTEYGADTMAGLHAVVDTPWSEEYQVRFLEMHHRVFDRVDA
EEEHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
VIGEHIWNFADFATSPHIIRVDGNKKGVFTRDRHPKSAAFSVRRRWRPQA
HHHHHHHHHHHHCCCCEEEEECCCCCCCEECCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3534890; 8125312; 2103475; 9097039; 9278503 [H]