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The map label for this gene is tmk [H]

Identifier: 158314647

GI number: 158314647

Start: 3344342

End: 3345016

Strand: Direct

Name: tmk [H]

Synonym: Franean1_2826

Alternate gene names: 158314647

Gene position: 3344342-3345016 (Clockwise)

Preceding gene: 158314638

Following gene: 158314648

Centisome position: 37.23

GC content: 68.74

Gene sequence:

>675_bases
ATGCTCGTCAGTTTGGAAGGTCTTCCCGGGTCGGGGAAGTCGACGCAGGCTCGTCTGCTGGAGGGGCGTCTTCGCGGTGA
AGGACTCAGGGTCACCTATCTCCCGGATCTCGCCACCCTCGACACCGGGGATGTCGGGACGGCCCTGGTGGAGATCTTCT
CGTCGTCGGATGATCCGTTCCTGCGTCACGGGGACGTGGTGACCGAGTGCCTGTTGGCAGCGGCGGTGCGCGCGGACATC
GTGGCGACGAGGATCGAGCCAGCGCTCGATCATCACGATGTGGTGATCGAGGACCGCGGTGTGCACACCATGTTCTCTTA
CGGGTTGGCGTCCCTGATCCGGCAGCATGCGGCGGAGGTGGACGACGCTGTGTCCTGGCTGGATGGGTTGGGACGCCTTG
CCGGGCGGCGGGCGGACGTCGTGCTGTGGCTGTCGGCGCCGGTGGGCGAGATGGTCGTGCGGGCGGAGGCCCGTGACGGG
AGGCGGTGGACAGGTGAGCAGCGCGCGTACCTGTCGTTCGTGGATCTTGCCTATCAGGAGCTGGCCGCACGCGACGCCGG
CATGGTCAGGGTGCCGACGGCCGGGCAGGCGCCGGAGGCCGTGCACGCGGCCGTCTGGGAGGTGGTCGCCGCACAGCTGA
AGCGGCCTGCCCGCAGGGCATCCGCAGGGGGTTGA

Upstream 100 bases:

>100_bases
TCCTGGCTCGGGTGCGGCAGCTATGGGAGCCCGGCGCGACGGCTGATGCTGGTGTCCTAGCCCGCCCTTCGAGGGTCGCC
ACCGTGATCGGAGTGTTGGG

Downstream 100 bases:

>100_bases
GCCCGTGTGTGGCGGGTGACCCTCGCCCCGTAGGCTTCGTGTGTTGTGAAGCCGTCACTGTCTGATGCGCCGACGATGGC
ACCTTCCTCGACGCCTGCGC

Product: thymidylate kinase

Products: NA

Alternate protein names: dTMP kinase [H]

Number of amino acids: Translated: 224; Mature: 224

Protein sequence:

>224_residues
MLVSLEGLPGSGKSTQARLLEGRLRGEGLRVTYLPDLATLDTGDVGTALVEIFSSSDDPFLRHGDVVTECLLAAAVRADI
VATRIEPALDHHDVVIEDRGVHTMFSYGLASLIRQHAAEVDDAVSWLDGLGRLAGRRADVVLWLSAPVGEMVVRAEARDG
RRWTGEQRAYLSFVDLAYQELAARDAGMVRVPTAGQAPEAVHAAVWEVVAAQLKRPARRASAGG

Sequences:

>Translated_224_residues
MLVSLEGLPGSGKSTQARLLEGRLRGEGLRVTYLPDLATLDTGDVGTALVEIFSSSDDPFLRHGDVVTECLLAAAVRADI
VATRIEPALDHHDVVIEDRGVHTMFSYGLASLIRQHAAEVDDAVSWLDGLGRLAGRRADVVLWLSAPVGEMVVRAEARDG
RRWTGEQRAYLSFVDLAYQELAARDAGMVRVPTAGQAPEAVHAAVWEVVAAQLKRPARRASAGG
>Mature_224_residues
MLVSLEGLPGSGKSTQARLLEGRLRGEGLRVTYLPDLATLDTGDVGTALVEIFSSSDDPFLRHGDVVTECLLAAAVRADI
VATRIEPALDHHDVVIEDRGVHTMFSYGLASLIRQHAAEVDDAVSWLDGLGRLAGRRADVVLWLSAPVGEMVVRAEARDG
RRWTGEQRAYLSFVDLAYQELAARDAGMVRVPTAGQAPEAVHAAVWEVVAAQLKRPARRASAGG

Specific function: Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis [H]

COG id: COG0125

COG function: function code F; Thymidylate kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thymidylate kinase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018095
- InterPro:   IPR018094 [H]

Pfam domain/function: PF02223 Thymidylate_kin [H]

EC number: =2.7.4.9 [H]

Molecular weight: Translated: 24044; Mature: 24044

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLVSLEGLPGSGKSTQARLLEGRLRGEGLRVTYLPDLATLDTGDVGTALVEIFSSSDDPF
CEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCC
LRHGDVVTECLLAAAVRADIVATRIEPALDHHDVVIEDRGVHTMFSYGLASLIRQHAAEV
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
DDAVSWLDGLGRLAGRRADVVLWLSAPVGEMVVRAEARDGRRWTGEQRAYLSFVDLAYQE
HHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LAARDAGMVRVPTAGQAPEAVHAAVWEVVAAQLKRPARRASAGG
HHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLVSLEGLPGSGKSTQARLLEGRLRGEGLRVTYLPDLATLDTGDVGTALVEIFSSSDDPF
CEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCC
LRHGDVVTECLLAAAVRADIVATRIEPALDHHDVVIEDRGVHTMFSYGLASLIRQHAAEV
HHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHH
DDAVSWLDGLGRLAGRRADVVLWLSAPVGEMVVRAEARDGRRWTGEQRAYLSFVDLAYQE
HHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
LAARDAGMVRVPTAGQAPEAVHAAVWEVVAAQLKRPARRASAGG
HHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA