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The map label for this gene is mutT [C]

Identifier: 158314638

GI number: 158314638

Start: 3333846

End: 3334289

Strand: Direct

Name: mutT [C]

Synonym: Franean1_2817

Alternate gene names: 158314638

Gene position: 3333846-3334289 (Clockwise)

Preceding gene: 158314637

Following gene: 158314647

Centisome position: 37.12

GC content: 60.59

Gene sequence:

>444_bases
GTGCCGGAACGTTACCGCAGCATCGTTGACGTCTATGTCCTGCTCATACGAGACGACAAGATCCTCCTCATGGAGCGCGC
CAACACCGGATACGCCGACGGCCAGCTCTGCCCGCCCAGCGGCCATCTCGAAGAGGGTGAGTCTGTTGTTGATGGTGCGG
TGCGCGAGGCCGCGGAGGAGGTCGGCATTACACTCGACCCGGACGACCTTCAGTGTGTGCACGTTGTACATCACCGCAAC
CCGCAGGGCCAAGGGCGCATCGGGTTCTTCTTCTGCACCGACAGATGGGAGGGAGAACCAGAAAATCAGGAACCCCGCAA
ATGCGCTCGCCTACTCTGGATTGACCCTGATCGCCTACCGCCAAATACGGTTGGGTACACAGCCGCAGCCGTCGCCAAAA
TCCGAAGCGGCCGCACATTCTCGATTCACGGCTGGGAGACATGA

Upstream 100 bases:

>100_bases
AGAAATGTCGCCCGTCTTGTCCCGCCCCGCACCGACCCGCACCTCGTCGGCCCTTGCTGACGGACCCCTACTCGCCCCAC
CACATGTTGTGAGGAGAGCC

Downstream 100 bases:

>100_bases
GGGCATTTCCAGGCTGTAGCAAGCCCGGTTCCGTGCCGGTCCGAGTAGCTCGGCACGGCCATGAGCGAGTTGTTAATAAC
CGCCTCTATTGATGAACGAG

Product: NUDIX hydrolase

Products: 8-Oxo-Dgmp; Pyrophosphate. [C]

Alternate protein names: MutT-Family Protein; MutT Family Protein; Nudix Hydrolase Family Protein; MutT-Like Protein; NUDIX Family Hydrolase; ADP-Ribose Pyrophosphatase; MutT/Nudix Family Protein; Nudix Hydrolase; ADP-Ribose Pyrophosphatase-Like Protein; Isopentenyl-Diphosphate Delta-Isomerase; Dihydrofolate Reductase; Hydrolase NUDIX Family

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MPERYRSIVDVYVLLIRDDKILLMERANTGYADGQLCPPSGHLEEGESVVDGAVREAAEEVGITLDPDDLQCVHVVHHRN
PQGQGRIGFFFCTDRWEGEPENQEPRKCARLLWIDPDRLPPNTVGYTAAAVAKIRSGRTFSIHGWET

Sequences:

>Translated_147_residues
MPERYRSIVDVYVLLIRDDKILLMERANTGYADGQLCPPSGHLEEGESVVDGAVREAAEEVGITLDPDDLQCVHVVHHRN
PQGQGRIGFFFCTDRWEGEPENQEPRKCARLLWIDPDRLPPNTVGYTAAAVAKIRSGRTFSIHGWET
>Mature_146_residues
PERYRSIVDVYVLLIRDDKILLMERANTGYADGQLCPPSGHLEEGESVVDGAVREAAEEVGITLDPDDLQCVHVVHHRNP
QGQGRIGFFFCTDRWEGEPENQEPRKCARLLWIDPDRLPPNTVGYTAAAVAKIRSGRTFSIHGWET

Specific function: Involved In The Go System Responsible For Removing An Oxidatively Damaged Form Of Guanine (7,8-Dihydro-8-Oxoguanine) From DNA And The Nucleotide Pool. 8-Oxo-Dgtp Is Inserted Opposite Da And Dc Residues Of Template DNA With Almost Equal Efficiency Thus Le

COG id: COG1051

COG function: function code F; ADP-ribose pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.6.1.- [C]

Molecular weight: Translated: 16542; Mature: 16411

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPERYRSIVDVYVLLIRDDKILLMERANTGYADGQLCPPSGHLEEGESVVDGAVREAAEE
CCHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHH
VGITLDPDDLQCVHVVHHRNPQGQGRIGFFFCTDRWEGEPENQEPRKCARLLWIDPDRLP
CCCEECCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHEEEEECCCCCC
PNTVGYTAAAVAKIRSGRTFSIHGWET
CCCCCHHHHHHHHHHCCCEEEEECCCC
>Mature Secondary Structure 
PERYRSIVDVYVLLIRDDKILLMERANTGYADGQLCPPSGHLEEGESVVDGAVREAAEE
CHHHHHHHHHEEEEECCCEEEEEEECCCCCCCCEECCCCCCCCCCHHHHHHHHHHHHHH
VGITLDPDDLQCVHVVHHRNPQGQGRIGFFFCTDRWEGEPENQEPRKCARLLWIDPDRLP
CCCEECCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHEEEEECCCCCC
PNTVGYTAAAVAKIRSGRTFSIHGWET
CCCCCHHHHHHHHHHCCCEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 8-Oxo-Dgtp; H2O [C]

Specific reaction: 8-Oxo-Dgtp + H2O = 8-Oxo-Dgmp + Pyrophosphate. [C]

General reaction: Hydrolase; Acting on acid anhydrides; In phosphorus-containing anhydrides [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA