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The map label for this gene is fabF [C]

Identifier: 158314224

GI number: 158314224

Start: 2848371

End: 2849657

Strand: Direct

Name: fabF [C]

Synonym: Franean1_2394

Alternate gene names: 158314224

Gene position: 2848371-2849657 (Clockwise)

Preceding gene: 158314223

Following gene: 158314225

Centisome position: 31.71

GC content: 76.92

Gene sequence:

>1287_bases
ATGACCGTCCTCGACACCGCGCCGTCCGGGACGGCCGGCCCGGCCCGGCCGGCCGCGGGCGCGGTGCGGCCGGTCATCAC
CGGGCTCGGGGTCATCGCGCCCAGCGGGGTGGGCCTCGACGCGTACTGGGCCTCGACGCTGCGCGGCGAGCTGCGCGTCG
CGCCGATCACCCGCTTCGACGCGAGCCGCTACGACACCCGGATCGCCGGCGAGGTCCCCGACTTCGCCGCCGAGGAGTTC
GTCGACCACCGCTACCTCGTGCAGACCGACCGCTGGACCTGGATGGGCATGGCCGCGTCCAAGCTGGCGCTGGCCGACGC
AGCCTACGACCCGGCCGAGCACGACCCGTACGAGACGTCGGTGGTCTTCGGCAGCGGCTCGGGGGGCAACGACTTCGGCC
AGCGGGAGCTGTCCCGGCTGTGGACGCGGGGGCGCACCGCGGTCAGCGTCTACCAGTCGATCGCCTGGTTCTACGCGGCG
ACGACCGGCCAGACCTCGATCCGGCACGGGCTCAAGGGCCCGTCGGGCGTCCTCGTCTCCGACGGCGCCGGCGGCGTCGA
CAGCCTCGCCCAGGCCCGGCGGACCATCCGGCGCGGCACCCCCACGGTGCTCGCCGGCGGCGCCGAGTGCGGGCTGACGC
CGTACGCGCTGACCTGCCACCTCAGCAGCGGCCGGGTCAGCTCCGCGGCGAGCCCCGCGGACGGCTACAAGCCGTTCGAC
GTCCGCGCCAACGGTTACCTGCCCGGTGAGGGCGGGGCGACCCTGCTCGTCGAGGACCCGGCTGCCGCGGCCCGCCGCGG
CGCCCGCGTCTACGGCGAGATCGCCGGCTACGCGGCCACCCACGACGGCGCGCACCACGAGCAGGCGCCGGCGGACTCGC
GCTGGCTGGCCGCGGCGATGCGCCGCGCGCTCGCCGACGCGGAGCTCACCCCCGCCGACGTCGACGTCGTGTTCGCCGAC
GGCGCCGGCTCCCCGGACCTCGACGCGCTGGAGGCGGAGGCCATCCGGGCCGTCTTCGGCGCCGGAGCGGTGCCCGTCAC
CGCCCCGCAGGGGCTCATCGGACGGCTGTGCGCCGGCGGCTCCGCCCTCGCCGCGGCGACCGCGCTGCTGTCGATCCGCG
ACGGGGTGATCCCCGCCGTGGGCAACCTCGACGAGCCCGACCCCGCCCACGGCCTCGACCTGGTGCGCTCGCCGCGTGAG
GGCCGTGTCCGGGCCGCGCTGGTCAACGCGCGCGGCCACGGCGGGTTCAACAGCTCGCTCGTCCTGCGGGCGGTCGACAC
CGACTGA

Upstream 100 bases:

>100_bases
CGAACACCGCCCGCGACCACACGGTGGACGCGGCGCTGTCGGTCGGCAGCGGGTTCGGCGGGTTCCAGTCGGCCATCGTC
CTGACCTCGGCGGACCGGGC

Downstream 100 bases:

>100_bases
CCTGCCTCTCCGGCGCGCCGACGACGCCGTCGGCGCGCCGGGGGATCCCGGGTGGCCAAGGCCACCGGAACGTTCCAGAC
TCACCTTTCGAGAGGATCAC

Product: beta-ketoacyl synthase

Products: NA

Alternate protein names: actI ORF2 [H]

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MTVLDTAPSGTAGPARPAAGAVRPVITGLGVIAPSGVGLDAYWASTLRGELRVAPITRFDASRYDTRIAGEVPDFAAEEF
VDHRYLVQTDRWTWMGMAASKLALADAAYDPAEHDPYETSVVFGSGSGGNDFGQRELSRLWTRGRTAVSVYQSIAWFYAA
TTGQTSIRHGLKGPSGVLVSDGAGGVDSLAQARRTIRRGTPTVLAGGAECGLTPYALTCHLSSGRVSSAASPADGYKPFD
VRANGYLPGEGGATLLVEDPAAAARRGARVYGEIAGYAATHDGAHHEQAPADSRWLAAAMRRALADAELTPADVDVVFAD
GAGSPDLDALEAEAIRAVFGAGAVPVTAPQGLIGRLCAGGSALAAATALLSIRDGVIPAVGNLDEPDPAHGLDLVRSPRE
GRVRAALVNARGHGGFNSSLVLRAVDTD

Sequences:

>Translated_428_residues
MTVLDTAPSGTAGPARPAAGAVRPVITGLGVIAPSGVGLDAYWASTLRGELRVAPITRFDASRYDTRIAGEVPDFAAEEF
VDHRYLVQTDRWTWMGMAASKLALADAAYDPAEHDPYETSVVFGSGSGGNDFGQRELSRLWTRGRTAVSVYQSIAWFYAA
TTGQTSIRHGLKGPSGVLVSDGAGGVDSLAQARRTIRRGTPTVLAGGAECGLTPYALTCHLSSGRVSSAASPADGYKPFD
VRANGYLPGEGGATLLVEDPAAAARRGARVYGEIAGYAATHDGAHHEQAPADSRWLAAAMRRALADAELTPADVDVVFAD
GAGSPDLDALEAEAIRAVFGAGAVPVTAPQGLIGRLCAGGSALAAATALLSIRDGVIPAVGNLDEPDPAHGLDLVRSPRE
GRVRAALVNARGHGGFNSSLVLRAVDTD
>Mature_427_residues
TVLDTAPSGTAGPARPAAGAVRPVITGLGVIAPSGVGLDAYWASTLRGELRVAPITRFDASRYDTRIAGEVPDFAAEEFV
DHRYLVQTDRWTWMGMAASKLALADAAYDPAEHDPYETSVVFGSGSGGNDFGQRELSRLWTRGRTAVSVYQSIAWFYAAT
TGQTSIRHGLKGPSGVLVSDGAGGVDSLAQARRTIRRGTPTVLAGGAECGLTPYALTCHLSSGRVSSAASPADGYKPFDV
RANGYLPGEGGATLLVEDPAAAARRGARVYGEIAGYAATHDGAHHEQAPADSRWLAAAMRRALADAELTPADVDVVFADG
AGSPDLDALEAEAIRAVFGAGAVPVTAPQGLIGRLCAGGSALAAATALLSIRDGVIPAVGNLDEPDPAHGLDLVRSPREG
RVRAALVNARGHGGFNSSLVLRAVDTD

Specific function: Catalyzes The Condensation Reaction Of Fatty Acid Synthesis By The Addition To An Acyl Acceptor Of Two Carbons From Malonyl-Acp. Has A Preference For Short Chain Acid Substrates And May Function To Supply The Octanoic Substrates For Lipoic Acid Biosynthe

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=414, Percent_Identity=27.536231884058, Blast_Score=145, Evalue=7e-35,
Organism=Escherichia coli, GI1787337, Length=411, Percent_Identity=29.9270072992701, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI1788663, Length=418, Percent_Identity=25.5980861244019, Blast_Score=93, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71983541, Length=410, Percent_Identity=27.0731707317073, Blast_Score=138, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI71983535, Length=248, Percent_Identity=30.6451612903226, Blast_Score=121, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6320904, Length=441, Percent_Identity=26.7573696145125, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24644341, Length=424, Percent_Identity=30.188679245283, Blast_Score=132, Evalue=4e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000794
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: 2.3.1.-

Molecular weight: Translated: 44108; Mature: 43976

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVLDTAPSGTAGPARPAAGAVRPVITGLGVIAPSGVGLDAYWASTLRGELRVAPITRFD
CCEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEEECCC
ASRYDTRIAGEVPDFAAEEFVDHRYLVQTDRWTWMGMAASKLALADAAYDPAEHDPYETS
CCCCCCEECCCCCCHHHHHHHCCCEEEEECCEEEECHHHHHHHHHHCCCCCCCCCCCCEE
VVFGSGSGGNDFGQRELSRLWTRGRTAVSVYQSIAWFYAATTGQTSIRHGLKGPSGVLVS
EEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCHHHHHCCCCCCCEEEE
DGAGGVDSLAQARRTIRRGTPTVLAGGAECGLTPYALTCHLSSGRVSSAASPADGYKPFD
CCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEE
VRANGYLPGEGGATLLVEDPAAAARRGARVYGEIAGYAATHDGAHHEQAPADSRWLAAAM
EEECCCCCCCCCCEEEEECCHHHHHCCCHHHHHHHCEEECCCCCCCCCCCCCHHHHHHHH
RRALADAELTPADVDVVFADGAGSPDLDALEAEAIRAVFGAGAVPVTAPQGLIGRLCAGG
HHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
SALAAATALLSIRDGVIPAVGNLDEPDPAHGLDLVRSPREGRVRAALVNARGHGGFNSSL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCCCCCE
VLRAVDTD
EEEEECCC
>Mature Secondary Structure 
TVLDTAPSGTAGPARPAAGAVRPVITGLGVIAPSGVGLDAYWASTLRGELRVAPITRFD
CEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCEEEEEEECCC
ASRYDTRIAGEVPDFAAEEFVDHRYLVQTDRWTWMGMAASKLALADAAYDPAEHDPYETS
CCCCCCEECCCCCCHHHHHHHCCCEEEEECCEEEECHHHHHHHHHHCCCCCCCCCCCCEE
VVFGSGSGGNDFGQRELSRLWTRGRTAVSVYQSIAWFYAATTGQTSIRHGLKGPSGVLVS
EEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHEECCCCHHHHHCCCCCCCEEEE
DGAGGVDSLAQARRTIRRGTPTVLAGGAECGLTPYALTCHLSSGRVSSAASPADGYKPFD
CCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCEE
VRANGYLPGEGGATLLVEDPAAAARRGARVYGEIAGYAATHDGAHHEQAPADSRWLAAAM
EEECCCCCCCCCCEEEEECCHHHHHCCCHHHHHHHCEEECCCCCCCCCCCCCHHHHHHHH
RRALADAELTPADVDVVFADGAGSPDLDALEAEAIRAVFGAGAVPVTAPQGLIGRLCAGG
HHHHHCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCC
SALAAATALLSIRDGVIPAVGNLDEPDPAHGLDLVRSPREGRVRAALVNARGHGGFNSSL
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHCCCCCCCEEEEEEECCCCCCCCCCE
VLRAVDTD
EEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1527048; 12000953 [H]