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The map label for this gene is mmpL3 [H]

Identifier: 158312513

GI number: 158312513

Start: 766611

End: 769001

Strand: Direct

Name: mmpL3 [H]

Synonym: Franean1_0656

Alternate gene names: 158312513

Gene position: 766611-769001 (Clockwise)

Preceding gene: 158312511

Following gene: 158312520

Centisome position: 8.53

GC content: 73.19

Gene sequence:

>2391_bases
GTGTTCACGGCAGTAGCCAAGCTAGTCACCCGCCGGCCCCGACTTGTGCTTCTGGTAACCCTTGCCGCGCTCCTGGGCGC
CGGGGTGCTGGGAATGGGCGCGTTCGGCAAGCTCGAGTCGGCGGGGTTCGACGACCCCGCCTCCGACTCCAGCCGGGCCG
CCGACCTCGTCGACACGAAGTTCGGTGGGGAGCCGAACCTCGTCCTGCTCGTCACGGCCCGCGCCGGGGCCCCAGGCACG
GACCCCCCGGCCGTCGACACCCCCGCGGTGGCCGACGCCGGCCGTCGCCTCGCCACCGAACTGGCCGCCCAGCCCGGGGT
GACCAACGTGTCGTCCTACTGGACCGGGGCCTCGCCGCTGGTCTCCGACGACGGCCGGGCCGCGCTGGTCCTGGCCAGCG
TGGACGACGACCACGAGTCCGACCTCGTCGCGAAGTACGAGGACCTGTACAAGGCCGGCCAGCCCGGCGGGCCCGACGCC
GACTCCCCGGTCACAGTCCGCCCCGGTGGCGCGGCGACCGTCGGGGAGGACATCAACGGCCAGGTGGGCGCGGACCTGGC
CGTGGCCGAGTCCATCGCGATACCGATCACGATGGTGCTGCTGGTGATCGCCTTCGGCGGCCTGCTCGCCGCGTTGCTGC
CGCTGGGGATCGGGCTGGTCGGCATCCTGGGCGGCTTCGCGTTCCTGTCGGTCGTCGGCGGCCTGACCGACGTGTCGATC
TTCGCCGTGAACCTGACCACGGCGCTCGGCCTCGGCCTCGGTATCGACTACGCGCTGCTCATGGTCAGCCGGTTCCGGGA
GGAGCTCGCCGCGGGCCACGACCGGGCCACGGCGGTGTCGACCACGGTGCGCACGGCCGGTCGCACGATTCTGTTCAGCG
GTGCGACGGTGATCGTCGCGCTCGCGGTGATGCTGGTCTTCCCGCCGTACTTCCTGAAGTCGATGGCATACGCGGGCATC
GCCGTCACCGCGGTCGCCGTGATCACCGCCGTGACGGCGCTGCCCGCCGTGCTCATGCTGCTCGGCCCGCGGGTGAACGC
GCTGCGCGTCGGCGGCCTGATCGGACGGCTGCGCCGCTGCCGGGGCGAGTCCTCGGCCGTTGCGGGAGTCCCGACCACCA
CGAGCGCCGCGGCGGGTGGGGGAGCGCCCGGGGCGGAGCGGGAGGTGCCGCGGGAGGCCGTCGAGTCGCCGTTCTGGCGG
CGGGTGGCAACCACCGTCATGCGCCGCCCGCTGCTGACCGGGCTGCCCGTGATTGCACTGCTCCTCGCGCTCGGCGCGCC
GTTCCTGCACGTCAAGTTCGGCACCCCGGACGACCGGGTCCTGCGCGAGCGCGCCTCCAGCCGGGCCGTCGGGGACGTCC
TGCGCGACGACTTCTCCTCCAACGACGCCGGGGCGATCGTCGTCGTCCTCACCGGCCCGACCGAGCGGCTCGGTGCGACG
GGCATCGCCGACTACGCCACGGAGCTGTCCGGGCTCGACGGCGTGGCCCGGGTCGACAGCTCCGCGGGCATCGTGCTCGA
CGGGCGGGTCGTCGTGCCACCGGGCCCGACCACCGAGCGGTACGCGGCCGAGAACGCCGCCTACCTGCGGGTGGTGCCCT
CGGTGGAGCCGCACTCCGACGAGGCCCAGGCGTTGGTCGGCGTGATCCGGCACACCGCCACCCCGGCGGGCACCCAGGCG
CTGGTCGGCGGTCCGCCGGCGGTGCTCGTCGACGGCAAGGCGACCATCGGCGACCGGCTCCCGCTGGCCATCGGCCTGAT
CGCGCTGGCCACGTTCGTCCTGCTGTTCCTGTTCACCGGCAGCGTGCTGCTGCCGCTGAAGGCGATCCTGATGAACGGGC
TGACGCTGACCTCCGTCTTCGGCGTGGCTGTCTGGATCTTCCAGGACGGTCATCTCTCCGGGGCGCTCGGCTTCACCCCG
GGCCCGCTGGACACGTCCATGCCGGTGCTGCTGTTCTGCATCGCGTTCGGCCTGAGCATGGACTACGAGGTCTTCCTGCT
CTCCCGGATCAAGGAGGAGCACGACGCGGGCGCGTCGAACACCGAGGCGGTCGCCACCGGCCTCGCCCGCACCGGTCGCC
TCGTGACGACCGCCGCGGCGCTGCTCGCGGTCACCTTCCTGGCCTTCGGGACGTCCTCGGTGCGGTTCATACAGATGTTC
GGCCTGGGCACGGCTCTGGCGATCCTGCTGGACGCGTCCCTGATCCGCGGGGTGCTGGTGCCGGCGTTCATGCGGGTGGC
CGGGCAGGCCAACTGGTGGGCGCCGAAGCCGCTGCGGGCGCTGCACGCCCGGATCGGCCTCAGCGAAGGCTCCGGCGAGG
GCCCCGGCGCGGGGCCCACCGCCGAGGGAGTCAGTAGCGTTCGAAGCCCCGCCGGCGCTCCCAGTCGGTGA

Upstream 100 bases:

>100_bases
AGCGGTGAGCGGTGTCAACTTTCGAGAACAGGGGTCTTGACGGCGACCGGTGTTTGAGAACACTGTTCTCTCAAGCGATC
GGTTCTCTCGGGAGGGTTCC

Downstream 100 bases:

>100_bases
CCGTCCGCTCGTAGCCGGCCAGCTCGACGTCGGCGGCGTGCGCCAGATGGTCGACGACCCGCTCGCCGAACGCGGCCCGG
GCCGTGGCGCTCTCCCGCCA

Product: MMPL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 796; Mature: 796

Protein sequence:

>796_residues
MFTAVAKLVTRRPRLVLLVTLAALLGAGVLGMGAFGKLESAGFDDPASDSSRAADLVDTKFGGEPNLVLLVTARAGAPGT
DPPAVDTPAVADAGRRLATELAAQPGVTNVSSYWTGASPLVSDDGRAALVLASVDDDHESDLVAKYEDLYKAGQPGGPDA
DSPVTVRPGGAATVGEDINGQVGADLAVAESIAIPITMVLLVIAFGGLLAALLPLGIGLVGILGGFAFLSVVGGLTDVSI
FAVNLTTALGLGLGIDYALLMVSRFREELAAGHDRATAVSTTVRTAGRTILFSGATVIVALAVMLVFPPYFLKSMAYAGI
AVTAVAVITAVTALPAVLMLLGPRVNALRVGGLIGRLRRCRGESSAVAGVPTTTSAAAGGGAPGAEREVPREAVESPFWR
RVATTVMRRPLLTGLPVIALLLALGAPFLHVKFGTPDDRVLRERASSRAVGDVLRDDFSSNDAGAIVVVLTGPTERLGAT
GIADYATELSGLDGVARVDSSAGIVLDGRVVVPPGPTTERYAAENAAYLRVVPSVEPHSDEAQALVGVIRHTATPAGTQA
LVGGPPAVLVDGKATIGDRLPLAIGLIALATFVLLFLFTGSVLLPLKAILMNGLTLTSVFGVAVWIFQDGHLSGALGFTP
GPLDTSMPVLLFCIAFGLSMDYEVFLLSRIKEEHDAGASNTEAVATGLARTGRLVTTAAALLAVTFLAFGTSSVRFIQMF
GLGTALAILLDASLIRGVLVPAFMRVAGQANWWAPKPLRALHARIGLSEGSGEGPGAGPTAEGVSSVRSPAGAPSR

Sequences:

>Translated_796_residues
MFTAVAKLVTRRPRLVLLVTLAALLGAGVLGMGAFGKLESAGFDDPASDSSRAADLVDTKFGGEPNLVLLVTARAGAPGT
DPPAVDTPAVADAGRRLATELAAQPGVTNVSSYWTGASPLVSDDGRAALVLASVDDDHESDLVAKYEDLYKAGQPGGPDA
DSPVTVRPGGAATVGEDINGQVGADLAVAESIAIPITMVLLVIAFGGLLAALLPLGIGLVGILGGFAFLSVVGGLTDVSI
FAVNLTTALGLGLGIDYALLMVSRFREELAAGHDRATAVSTTVRTAGRTILFSGATVIVALAVMLVFPPYFLKSMAYAGI
AVTAVAVITAVTALPAVLMLLGPRVNALRVGGLIGRLRRCRGESSAVAGVPTTTSAAAGGGAPGAEREVPREAVESPFWR
RVATTVMRRPLLTGLPVIALLLALGAPFLHVKFGTPDDRVLRERASSRAVGDVLRDDFSSNDAGAIVVVLTGPTERLGAT
GIADYATELSGLDGVARVDSSAGIVLDGRVVVPPGPTTERYAAENAAYLRVVPSVEPHSDEAQALVGVIRHTATPAGTQA
LVGGPPAVLVDGKATIGDRLPLAIGLIALATFVLLFLFTGSVLLPLKAILMNGLTLTSVFGVAVWIFQDGHLSGALGFTP
GPLDTSMPVLLFCIAFGLSMDYEVFLLSRIKEEHDAGASNTEAVATGLARTGRLVTTAAALLAVTFLAFGTSSVRFIQMF
GLGTALAILLDASLIRGVLVPAFMRVAGQANWWAPKPLRALHARIGLSEGSGEGPGAGPTAEGVSSVRSPAGAPSR
>Mature_796_residues
MFTAVAKLVTRRPRLVLLVTLAALLGAGVLGMGAFGKLESAGFDDPASDSSRAADLVDTKFGGEPNLVLLVTARAGAPGT
DPPAVDTPAVADAGRRLATELAAQPGVTNVSSYWTGASPLVSDDGRAALVLASVDDDHESDLVAKYEDLYKAGQPGGPDA
DSPVTVRPGGAATVGEDINGQVGADLAVAESIAIPITMVLLVIAFGGLLAALLPLGIGLVGILGGFAFLSVVGGLTDVSI
FAVNLTTALGLGLGIDYALLMVSRFREELAAGHDRATAVSTTVRTAGRTILFSGATVIVALAVMLVFPPYFLKSMAYAGI
AVTAVAVITAVTALPAVLMLLGPRVNALRVGGLIGRLRRCRGESSAVAGVPTTTSAAAGGGAPGAEREVPREAVESPFWR
RVATTVMRRPLLTGLPVIALLLALGAPFLHVKFGTPDDRVLRERASSRAVGDVLRDDFSSNDAGAIVVVLTGPTERLGAT
GIADYATELSGLDGVARVDSSAGIVLDGRVVVPPGPTTERYAAENAAYLRVVPSVEPHSDEAQALVGVIRHTATPAGTQA
LVGGPPAVLVDGKATIGDRLPLAIGLIALATFVLLFLFTGSVLLPLKAILMNGLTLTSVFGVAVWIFQDGHLSGALGFTP
GPLDTSMPVLLFCIAFGLSMDYEVFLLSRIKEEHDAGASNTEAVATGLARTGRLVTTAAALLAVTFLAFGTSSVRFIQMF
GLGTALAILLDASLIRGVLVPAFMRVAGQANWWAPKPLRALHARIGLSEGSGEGPGAGPTAEGVSSVRSPAGAPSR

Specific function: Unknown

COG id: COG2409

COG function: function code R; Predicted drug exporters of the RND superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mmpL family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004869
- InterPro:   IPR000731 [H]

Pfam domain/function: PF03176 MMPL [H]

EC number: NA

Molecular weight: Translated: 81211; Mature: 81211

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTAVAKLVTRRPRLVLLVTLAALLGAGVLGMGAFGKLESAGFDDPASDSSRAADLVDTK
CHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHC
FGGEPNLVLLVTARAGAPGTDPPAVDTPAVADAGRRLATELAAQPGVTNVSSYWTGASPL
CCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCC
VSDDGRAALVLASVDDDHESDLVAKYEDLYKAGQPGGPDADSPVTVRPGGAATVGEDING
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCC
QVGADLAVAESIAIPITMVLLVIAFGGLLAALLPLGIGLVGILGGFAFLSVVGGLTDVSI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHE
FAVNLTTALGLGLGIDYALLMVSRFREELAAGHDRATAVSTTVRTAGRTILFSGATVIVA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCHHHHHH
LAVMLVFPPYFLKSMAYAGIAVTAVAVITAVTALPAVLMLLGPRVNALRVGGLIGRLRRC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RGESSAVAGVPTTTSAAAGGGAPGAEREVPREAVESPFWRRVATTVMRRPLLTGLPVIAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
LLALGAPFLHVKFGTPDDRVLRERASSRAVGDVLRDDFSSNDAGAIVVVLTGPTERLGAT
HHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHCCC
GIADYATELSGLDGVARVDSSAGIVLDGRVVVPPGPTTERYAAENAAYLRVVPSVEPHSD
HHHHHHHHHCCCCCHHHCCCCCCEEECCEEEECCCCCCHHHHHCCCEEEEEECCCCCCCH
EAQALVGVIRHTATPAGTQALVGGPPAVLVDGKATIGDRLPLAIGLIALATFVLLFLFTG
HHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
SVLLPLKAILMNGLTLTSVFGVAVWIFQDGHLSGALGFTPGPLDTSMPVLLFCIAFGLSM
CHHHHHHHHHHCCCHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
DYEVFLLSRIKEEHDAGASNTEAVATGLARTGRLVTTAAALLAVTFLAFGTSSVRFIQMF
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GLGTALAILLDASLIRGVLVPAFMRVAGQANWWAPKPLRALHARIGLSEGSGEGPGAGPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
AEGVSSVRSPAGAPSR
HHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFTAVAKLVTRRPRLVLLVTLAALLGAGVLGMGAFGKLESAGFDDPASDSSRAADLVDTK
CHHHHHHHHHCCCCHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHC
FGGEPNLVLLVTARAGAPGTDPPAVDTPAVADAGRRLATELAAQPGVTNVSSYWTGASPL
CCCCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHCCCCCCC
VSDDGRAALVLASVDDDHESDLVAKYEDLYKAGQPGGPDADSPVTVRPGGAATVGEDING
CCCCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCCCCCC
QVGADLAVAESIAIPITMVLLVIAFGGLLAALLPLGIGLVGILGGFAFLSVVGGLTDVSI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHE
FAVNLTTALGLGLGIDYALLMVSRFREELAAGHDRATAVSTTVRTAGRTILFSGATVIVA
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCEEEECCHHHHHH
LAVMLVFPPYFLKSMAYAGIAVTAVAVITAVTALPAVLMLLGPRVNALRVGGLIGRLRRC
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
RGESSAVAGVPTTTSAAAGGGAPGAEREVPREAVESPFWRRVATTVMRRPLLTGLPVIAL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHH
LLALGAPFLHVKFGTPDDRVLRERASSRAVGDVLRDDFSSNDAGAIVVVLTGPTERLGAT
HHHHCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCHHHHCCC
GIADYATELSGLDGVARVDSSAGIVLDGRVVVPPGPTTERYAAENAAYLRVVPSVEPHSD
HHHHHHHHHCCCCCHHHCCCCCCEEECCEEEECCCCCCHHHHHCCCEEEEEECCCCCCCH
EAQALVGVIRHTATPAGTQALVGGPPAVLVDGKATIGDRLPLAIGLIALATFVLLFLFTG
HHHHHHHHHHHCCCCCCCEEEECCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
SVLLPLKAILMNGLTLTSVFGVAVWIFQDGHLSGALGFTPGPLDTSMPVLLFCIAFGLSM
CHHHHHHHHHHCCCHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCC
DYEVFLLSRIKEEHDAGASNTEAVATGLARTGRLVTTAAALLAVTFLAFGTSSVRFIQMF
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHH
GLGTALAILLDASLIRGVLVPAFMRVAGQANWWAPKPLRALHARIGLSEGSGEGPGAGPT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCC
AEGVSSVRSPAGAPSR
HHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]