Click here to switch to the map view.

The map label for this gene is fhuA [H]

Identifier: 157964047

GI number: 157964047

Start: 5148872

End: 5151004

Strand: Reverse

Name: fhuA [H]

Synonym: Spea_4236

Alternate gene names: 157964047

Gene position: 5151004-5148872 (Counterclockwise)

Preceding gene: 157964048

Following gene: 157964046

Centisome position: 99.54

GC content: 44.49

Gene sequence:

>2133_bases
ATGTCTGTCGGGACGTCATTTAAGTTTTCTCGCGTAGGGTTGGCAATCGTTGCTGCATTGGCTTCATCAACTGCTTTTGC
TGAAGAAGCGACAGCAGAATCAAATGTTAAAGTTGATAGCAATATCGAGCGTATTTCCGTTACCGGACGCAGTTTTAATG
ATTATAACGCTGGCTCATCTTCTGGAGCTATGCGTGGTGACATCGACATCTTAGACACCCCTCAATCAGTTACTGTTATT
CCTGACTTTGTGACTGATGAGCAGTTAGCTACAAACCTTTCTGAAGTGCTAGTTAACGACTCGAGCGTAACTGGCGGCTC
TGAAAAGTGGAACCGCCAAGTATTTAATATTCGTGGTTTCGAACTTTCTTCTGGCTCAGGCTTCTTAATCAATGGTCAAC
AGCAGTGGTCTCACTACGTGCAGCCTATTGAAACACTACAACAAGTTGAAGTGTTAAAAGGTCCTTCTTCTATGTTATAT
GGTCAGTCTGGTCCTGGCGGCTTGATCAACATGGTTACCAAGAAGCCAACCTATGAAACGATGTTGGATATTGGCTTCGA
TACGGATGAGAATGGCTCGACACGTTTCCAGTTGGACGCTGGTGGTAGCTTAAACGAAGCAGAGACAATTCGTTACCGTA
CAGTGCTAGTTAAGCAAGATACGACTTATTGGAGAGAGTACCAAGATGGTACTAATCAAGAGCGTGACCGCTGGTTAGGT
TACCTAAACCTAGAGTTTGATATTACTGACGACTTAATGTTGTCACTTAAATATGACCATACTCAAGACAAGACGGGCAT
CGACCGCGGTGGTTGGTTAGATAGCAGCGGTGACCTGATTGGTGGCCGTGACATCATCTGGGATCAGCCTTGGGCGTTTA
CCGACAACACCATCTCTAATCTAGGTGCAGAGCTGACTTATCACTTGTCTGATGACTGGAAAGTGAAAGCGGGTTATAAC
GATCAGCAGTTTAATCGTCAGCGTTTAGACTCTTCTCCATCACTAATTAGTGGTTCTGACGATCCATTTACCGATGGCTA
CTATGTCAGCCCATTTGACCGTTATGATGACTGGCAGCATAAGACGGGCTATGTTGATTTCACTGGTAACTTCTATACTG
GTGACATAGAGCATCAGCTGCTTATCGGCGCTAATATGCTGGATTATTACTATGGTCAGCTAAAAGACTCAGGTGAGAAG
AAACAAGTTGTGATGCCTGGTCAGCCAATGCCTAAACCTGATCTAGATTATAATCGTGATGAAACTTTGTACGAGAGTGA
GTACAAGCACTACGGCTTCTATGTTCAAGATTTAGTTTCTATCACCGACGAATGGCAAGTGCTAGCTGGTGTACGTTATG
ACGAACAGAAGAAAGAGGGGGCGGGTAATAACAGTTATGCGGTCTCTCCTAAGTTTGGTGTGATTTACTCACCAGCCGAT
AATGGCAGTATCTATGTTAACTACTCTAAGAGCTTCACGCCGCAAGGGATAGTGAACGACATTGATGATGTTAATGATGG
TAAGAACCTAGATCCTGAATACGGTGAACAGTATGAGATTGGTACTAAGTGGGAGCTATTTGATGGCAGCTTACTATTAA
CTGGTGCGGTATTCGATATTACTGTTTCGAACGTGACCGTAACAGAAGAGATTGAAGGTAGCAGCCAAACCATCACGACC
CAGTCTGGTGAACAGCGCCATAAAGGTTTTGAAATGGGCGCTCAAGGTCAAGTTAGCGATAGCTGGTTTATGACGGGTTC
TATGATGTACTTAGATGCTGAGTATCTTCGTCCTGAAACAGATAGTTTAAATGGTAAGACTCCTGTTGATGCGCCTGAGT
GGTCAGCAAACGTCTGGACTCGTTATGAGATGACAGATGACTTAGCCCTTAACTTTGGTGCTATCTATGTGGGTGAGCGT
TTCGCTAATACCAGTAACAGCATTAGCAAAGACGGCTATGTGCGTTTCGATATGGGCGCTGCATACACTATGGACGTAAT
GGGGAGCGATGTTAGCATGCGTGTTAACGTGAAGAACCTATTCGATACAGATTATCTAGCTGGTGGCACCAACACTGATG
TTACTGTGGGTCAAGGTCGTCACTTTAGCTTGGCACTAGAAGCTAAGTTCTAA

Upstream 100 bases:

>100_bases
CTTGGCTTTGTAAAGAAGTGTAAAGAACCTTAAATAAAAATAGTTCTCATTTATATTGCGACTCAAATATTACATTCATG
TTTCATTATTGGGGTTGGAT

Downstream 100 bases:

>100_bases
ATAGCGAGTTAAAATCGAAAGAGAAAGCCTCAACCTTAAGTTGAGGCTTTTTTTTGTCTTTTATATCTTAAAATTGGCAA
TTAAGTTTCGTTTCCCTATA

Product: TonB-dependent siderophore receptor

Products: NA

Alternate protein names: Ferric hydroxamate receptor; Ferric hydroxamate uptake [H]

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MSVGTSFKFSRVGLAIVAALASSTAFAEEATAESNVKVDSNIERISVTGRSFNDYNAGSSSGAMRGDIDILDTPQSVTVI
PDFVTDEQLATNLSEVLVNDSSVTGGSEKWNRQVFNIRGFELSSGSGFLINGQQQWSHYVQPIETLQQVEVLKGPSSMLY
GQSGPGGLINMVTKKPTYETMLDIGFDTDENGSTRFQLDAGGSLNEAETIRYRTVLVKQDTTYWREYQDGTNQERDRWLG
YLNLEFDITDDLMLSLKYDHTQDKTGIDRGGWLDSSGDLIGGRDIIWDQPWAFTDNTISNLGAELTYHLSDDWKVKAGYN
DQQFNRQRLDSSPSLISGSDDPFTDGYYVSPFDRYDDWQHKTGYVDFTGNFYTGDIEHQLLIGANMLDYYYGQLKDSGEK
KQVVMPGQPMPKPDLDYNRDETLYESEYKHYGFYVQDLVSITDEWQVLAGVRYDEQKKEGAGNNSYAVSPKFGVIYSPAD
NGSIYVNYSKSFTPQGIVNDIDDVNDGKNLDPEYGEQYEIGTKWELFDGSLLLTGAVFDITVSNVTVTEEIEGSSQTITT
QSGEQRHKGFEMGAQGQVSDSWFMTGSMMYLDAEYLRPETDSLNGKTPVDAPEWSANVWTRYEMTDDLALNFGAIYVGER
FANTSNSISKDGYVRFDMGAAYTMDVMGSDVSMRVNVKNLFDTDYLAGGTNTDVTVGQGRHFSLALEAKF

Sequences:

>Translated_710_residues
MSVGTSFKFSRVGLAIVAALASSTAFAEEATAESNVKVDSNIERISVTGRSFNDYNAGSSSGAMRGDIDILDTPQSVTVI
PDFVTDEQLATNLSEVLVNDSSVTGGSEKWNRQVFNIRGFELSSGSGFLINGQQQWSHYVQPIETLQQVEVLKGPSSMLY
GQSGPGGLINMVTKKPTYETMLDIGFDTDENGSTRFQLDAGGSLNEAETIRYRTVLVKQDTTYWREYQDGTNQERDRWLG
YLNLEFDITDDLMLSLKYDHTQDKTGIDRGGWLDSSGDLIGGRDIIWDQPWAFTDNTISNLGAELTYHLSDDWKVKAGYN
DQQFNRQRLDSSPSLISGSDDPFTDGYYVSPFDRYDDWQHKTGYVDFTGNFYTGDIEHQLLIGANMLDYYYGQLKDSGEK
KQVVMPGQPMPKPDLDYNRDETLYESEYKHYGFYVQDLVSITDEWQVLAGVRYDEQKKEGAGNNSYAVSPKFGVIYSPAD
NGSIYVNYSKSFTPQGIVNDIDDVNDGKNLDPEYGEQYEIGTKWELFDGSLLLTGAVFDITVSNVTVTEEIEGSSQTITT
QSGEQRHKGFEMGAQGQVSDSWFMTGSMMYLDAEYLRPETDSLNGKTPVDAPEWSANVWTRYEMTDDLALNFGAIYVGER
FANTSNSISKDGYVRFDMGAAYTMDVMGSDVSMRVNVKNLFDTDYLAGGTNTDVTVGQGRHFSLALEAKF
>Mature_709_residues
SVGTSFKFSRVGLAIVAALASSTAFAEEATAESNVKVDSNIERISVTGRSFNDYNAGSSSGAMRGDIDILDTPQSVTVIP
DFVTDEQLATNLSEVLVNDSSVTGGSEKWNRQVFNIRGFELSSGSGFLINGQQQWSHYVQPIETLQQVEVLKGPSSMLYG
QSGPGGLINMVTKKPTYETMLDIGFDTDENGSTRFQLDAGGSLNEAETIRYRTVLVKQDTTYWREYQDGTNQERDRWLGY
LNLEFDITDDLMLSLKYDHTQDKTGIDRGGWLDSSGDLIGGRDIIWDQPWAFTDNTISNLGAELTYHLSDDWKVKAGYND
QQFNRQRLDSSPSLISGSDDPFTDGYYVSPFDRYDDWQHKTGYVDFTGNFYTGDIEHQLLIGANMLDYYYGQLKDSGEKK
QVVMPGQPMPKPDLDYNRDETLYESEYKHYGFYVQDLVSITDEWQVLAGVRYDEQKKEGAGNNSYAVSPKFGVIYSPADN
GSIYVNYSKSFTPQGIVNDIDDVNDGKNLDPEYGEQYEIGTKWELFDGSLLLTGAVFDITVSNVTVTEEIEGSSQTITTQ
SGEQRHKGFEMGAQGQVSDSWFMTGSMMYLDAEYLRPETDSLNGKTPVDAPEWSANVWTRYEMTDDLALNFGAIYVGERF
ANTSNSISKDGYVRFDMGAAYTMDVMGSDVSMRVNVKNLFDTDYLAGGTNTDVTVGQGRHFSLALEAKF

Specific function: This receptor binds the ferrichrome-iron ligand. It interacts with the tonB protein, which is responsible for energy coupling of the ferrichrome-promoted iron transport system. Acts as a receptor for bacteriophage T5 as well as T1, phi80 and colicin M. Bi

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=702, Percent_Identity=28.3475783475783, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1787344, Length=761, Percent_Identity=24.1787122207622, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787024, Length=373, Percent_Identity=24.3967828418231, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1790743, Length=652, Percent_Identity=22.3926380368098, Blast_Score=74, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 79204; Mature: 79072

Theoretical pI: Translated: 4.11; Mature: 4.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGTSFKFSRVGLAIVAALASSTAFAEEATAESNVKVDSNIERISVTGRSFNDYNAGSS
CCCCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCEECCCCEEEEEECCCCCCCCCCCC
SGAMRGDIDILDTPQSVTVIPDFVTDEQLATNLSEVLVNDSSVTGGSEKWNRQVFNIRGF
CCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECE
ELSSGSGFLINGQQQWSHYVQPIETLQQVEVLKGPSSMLYGQSGPGGLINMVTKKPTYET
EECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCEEEEEECCCCHHH
MLDIGFDTDENGSTRFQLDAGGSLNEAETIRYRTVLVKQDTTYWREYQDGTNQERDRWLG
HEEECCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEECCCHHHHHHCCCCCCCCHHEEE
YLNLEFDITDDLMLSLKYDHTQDKTGIDRGGWLDSSGDLIGGRDIIWDQPWAFTDNTISN
EEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCCEEEECCCCCCCCCHHHH
LGAELTYHLSDDWKVKAGYNDQQFNRQRLDSSPSLISGSDDPFTDGYYVSPFDRYDDWQH
CCCEEEEEECCCEEEECCCCHHHHHHHHCCCCCCEECCCCCCCCCCEEECCCCCCCCCCC
KTGYVDFTGNFYTGDIEHQLLIGANMLDYYYGQLKDSGEKKQVVMPGQPMPKPDLDYNRD
CCCEEEECCCEEECCCCEEEEECCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCC
ETLYESEYKHYGFYVQDLVSITDEWQVLAGVRYDEQKKEGAGNNSYAVSPKFGVIYSPAD
CCHHHCCHHHCCCHHHHHHHHCCCCEEEECCCCCHHHHCCCCCCCEEECCCCCEEECCCC
NGSIYVNYSKSFTPQGIVNDIDDVNDGKNLDPEYGEQYEIGTKWELFDGSLLLTGAVFDI
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEECCCEEEEEEEEEE
TVSNVTVTEEIEGSSQTITTQSGEQRHKGFEMGAQGQVSDSWFMTGSMMYLDAEYLRPET
EECCEEEEEECCCCCCEEEECCCHHHHCCCCCCCCCCCCCCEEEECEEEEEEHHHCCCCC
DSLNGKTPVDAPEWSANVWTRYEMTDDLALNFGAIYVGERFANTSNSISKDGYVRFDMGA
CCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCEEEEEHHHCCCCCCCCCCCEEEEECCC
AYTMDVMGSDVSMRVNVKNLFDTDYLAGGTNTDVTVGQGRHFSLALEAKF
EEEEEECCCCEEEEEEHHHHCCCCCCCCCCCCCEEECCCCEEEEEEEECC
>Mature Secondary Structure 
SVGTSFKFSRVGLAIVAALASSTAFAEEATAESNVKVDSNIERISVTGRSFNDYNAGSS
CCCCCCCHHHHHHHHHHHHHHCHHHHHHHCCCCCCEECCCCEEEEEECCCCCCCCCCCC
SGAMRGDIDILDTPQSVTVIPDFVTDEQLATNLSEVLVNDSSVTGGSEKWNRQVFNIRGF
CCCCCCCEEEEECCCCEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECE
ELSSGSGFLINGQQQWSHYVQPIETLQQVEVLKGPSSMLYGQSGPGGLINMVTKKPTYET
EECCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCCCCEEEEEECCCCHHH
MLDIGFDTDENGSTRFQLDAGGSLNEAETIRYRTVLVKQDTTYWREYQDGTNQERDRWLG
HEEECCCCCCCCCEEEEEECCCCCCCCCEEEEEEEEEECCCHHHHHHCCCCCCCCHHEEE
YLNLEFDITDDLMLSLKYDHTQDKTGIDRGGWLDSSGDLIGGRDIIWDQPWAFTDNTISN
EEEEEEECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEECCCEEEECCCCCCCCCHHHH
LGAELTYHLSDDWKVKAGYNDQQFNRQRLDSSPSLISGSDDPFTDGYYVSPFDRYDDWQH
CCCEEEEEECCCEEEECCCCHHHHHHHHCCCCCCEECCCCCCCCCCEEECCCCCCCCCCC
KTGYVDFTGNFYTGDIEHQLLIGANMLDYYYGQLKDSGEKKQVVMPGQPMPKPDLDYNRD
CCCEEEECCCEEECCCCEEEEECCHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCC
ETLYESEYKHYGFYVQDLVSITDEWQVLAGVRYDEQKKEGAGNNSYAVSPKFGVIYSPAD
CCHHHCCHHHCCCHHHHHHHHCCCCEEEECCCCCHHHHCCCCCCCEEECCCCCEEECCCC
NGSIYVNYSKSFTPQGIVNDIDDVNDGKNLDPEYGEQYEIGTKWELFDGSLLLTGAVFDI
CCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCEEEEECCCEEEEEEEEEE
TVSNVTVTEEIEGSSQTITTQSGEQRHKGFEMGAQGQVSDSWFMTGSMMYLDAEYLRPET
EECCEEEEEECCCCCCEEEECCCHHHHCCCCCCCCCCCCCCEEEECEEEEEEHHHCCCCC
DSLNGKTPVDAPEWSANVWTRYEMTDDLALNFGAIYVGERFANTSNSISKDGYVRFDMGA
CCCCCCCCCCCCCCCCCEEEEEECCCCEEEECCEEEEEHHHCCCCCCCCCCCEEEEECCC
AYTMDVMGSDVSMRVNVKNLFDTDYLAGGTNTDVTVGQGRHFSLALEAKF
EEEEEECCCCEEEEEEHHHHCCCCCCCCCCCCCEEECCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3079747; 8202364; 9278503; 2823072; 7515827; 8617231; 9856937; 9865695; 10850805 [H]