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The map label for this gene is srlR [H]

Identifier: 157964046

GI number: 157964046

Start: 5147965

End: 5148771

Strand: Reverse

Name: srlR [H]

Synonym: Spea_4235

Alternate gene names: 157964046

Gene position: 5148771-5147965 (Counterclockwise)

Preceding gene: 157964047

Following gene: 157964045

Centisome position: 99.5

GC content: 47.96

Gene sequence:

>807_bases
ATGTATCTTTCGAACCGAAACTTAGCGAAAGGTTTTATGAATAAACGAAACACTCAACAGCGACGCCACAGCATTATTAG
CCTGCTTAATCAGCAAGGCGAGGTGAGTGTTGAGGAGTTATCCTTACGTTTCGAAACCTCTGAAGTCACCATTCGTAAAG
ACTTAGCCACCCTAGAGAAGAGCGGCCTATTGCTACGCCGTTATGGTGGAGCTGTCGCCGTGCCAGATGAGGTGATGCAG
CAGTTCTCTGCCAAGATAGCGCCTAACAAGCTATCTATCGCTAGAGCCGCTGCTGAATTAATTAAAGATCATAATCGCAT
CATCATCGATAGCGGCAGCACCACATCAGGCTTGATCGGTGAGCTTAACAGTAAACGTGGTTTACTGGTGATGACCAACT
CATTGGCCTTGGCTAATGCGATTCACGACCTTGAAAACGAGCCGACCTTATTGATGACTGGAGGGACCTGGGACCCTCAC
TCTGAGTCCTTCCAGGGCCAGATTGCCGAGCAAGTACTACGGTCTTACAACTTCGATCAACTGTTTATCGGTGCAGACGG
TATCGATCTTCAGCGTGGAACTACAACCTTCAACGAACTAACCGGCTTAAGTAAGGTAATGGCCGAAGTATCACGTGAAG
TGGTGGTGATGCTCGAGTCAGAAAAGCTGGGTCGTCGTATTCCTAATCTTGAGCTACCTTGGAGCAAGATTAGTGTGCTG
GTAACAGACGATAAGTTGCCAAGCGAAGCGCTAGAGACAATTTCTAACCATGGGGTGCGAGTCATTCTTGCACCTTATGC
AGGGTAA

Upstream 100 bases:

>100_bases
ATAGCGAGTTAAAATCGAAAGAGAAAGCCTCAACCTTAAGTTGAGGCTTTTTTTTGTCTTTTATATCTTAAAATTGGCAA
TTAAGTTTCGTTTCCCTATA

Downstream 100 bases:

>100_bases
TGATTACAAGCACGTGGCTTGATGAACTATCCATTTCAAATTCAATTTTTAACTTTAACTCTCAAAGAGAGAAGCTAGGT
AACTAAATATGTGTGGAATC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MYLSNRNLAKGFMNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEKSGLLLRRYGGAVAVPDEVMQ
QFSAKIAPNKLSIARAAAELIKDHNRIIIDSGSTTSGLIGELNSKRGLLVMTNSLALANAIHDLENEPTLLMTGGTWDPH
SESFQGQIAEQVLRSYNFDQLFIGADGIDLQRGTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVL
VTDDKLPSEALETISNHGVRVILAPYAG

Sequences:

>Translated_268_residues
MYLSNRNLAKGFMNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEKSGLLLRRYGGAVAVPDEVMQ
QFSAKIAPNKLSIARAAAELIKDHNRIIIDSGSTTSGLIGELNSKRGLLVMTNSLALANAIHDLENEPTLLMTGGTWDPH
SESFQGQIAEQVLRSYNFDQLFIGADGIDLQRGTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVL
VTDDKLPSEALETISNHGVRVILAPYAG
>Mature_268_residues
MYLSNRNLAKGFMNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEKSGLLLRRYGGAVAVPDEVMQ
QFSAKIAPNKLSIARAAAELIKDHNRIIIDSGSTTSGLIGELNSKRGLLVMTNSLALANAIHDLENEPTLLMTGGTWDPH
SESFQGQIAEQVLRSYNFDQLFIGADGIDLQRGTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVL
VTDDKLPSEALETISNHGVRVILAPYAG

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=248, Percent_Identity=41.5322580645161, Blast_Score=193, Evalue=8e-51,
Organism=Escherichia coli, GI1789519, Length=269, Percent_Identity=39.7769516728625, Blast_Score=169, Evalue=2e-43,
Organism=Escherichia coli, GI226510968, Length=250, Percent_Identity=30, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788069, Length=251, Percent_Identity=29.4820717131474, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787540, Length=233, Percent_Identity=30.4721030042918, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=28.1124497991968, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1790635, Length=252, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI87082344, Length=244, Percent_Identity=26.2295081967213, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1790753, Length=256, Percent_Identity=24.21875, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 29571; Mature: 29571

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLSNRNLAKGFMNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEK
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCEEHHHHHHHHHH
SGLLLRRYGGAVAVPDEVMQQFSAKIAPNKLSIARAAAELIKDHNRIIIDSGSTTSGLIG
CCEEEEECCCCEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
ELNSKRGLLVMTNSLALANAIHDLENEPTLLMTGGTWDPHSESFQGQIAEQVLRSYNFDQ
CCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCE
LFIGADGIDLQRGTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVL
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHCCCCCCCCCCCCEEEE
VTDDKLPSEALETISNHGVRVILAPYAG
EECCCCCHHHHHHHHCCCEEEEEECCCC
>Mature Secondary Structure
MYLSNRNLAKGFMNKRNTQQRRHSIISLLNQQGEVSVEELSLRFETSEVTIRKDLATLEK
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEECCCEEHHHHHHHHHH
SGLLLRRYGGAVAVPDEVMQQFSAKIAPNKLSIARAAAELIKDHNRIIIDSGSTTSGLIG
CCEEEEECCCCEECCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEECCCCCCCHHH
ELNSKRGLLVMTNSLALANAIHDLENEPTLLMTGGTWDPHSESFQGQIAEQVLRSYNFDQ
CCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCCE
LFIGADGIDLQRGTTTFNELTGLSKVMAEVSREVVVMLESEKLGRRIPNLELPWSKISVL
EEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEECCHHHHCCCCCCCCCCCCEEEE
VTDDKLPSEALETISNHGVRVILAPYAG
EECCCCCHHHHHHHHCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]