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The map label for this gene is pdxY [H]

Identifier: 157963724

GI number: 157963724

Start: 4758754

End: 4759617

Strand: Reverse

Name: pdxY [H]

Synonym: Spea_3913

Alternate gene names: 157963724

Gene position: 4759617-4758754 (Counterclockwise)

Preceding gene: 157963725

Following gene: 157963720

Centisome position: 91.98

GC content: 47.57

Gene sequence:

>864_bases
ATGAAGCGGATTTTATCCATTCAATCCCATGTGGTATTTGGCTGTGCTGGCAACAGTAGTGCCGTATTCCCTATGCGTCG
TCTTGGTATGGAGGTTTGGCCGATTAATACGGTGCAGTTCTCTAACCATACTCAGTACGCACAAGGATGGGCGGGGATGA
TCATGCCTGCGGGTCAGATCACTGAGTTGGTACAGGGCCTAGATAATATTGGTCAGCTACAGACCTGCGATGCTTTACTC
AGTGGTTATCTCGGTAGCGCAGAGCAAGGCATTGAAATCACGGCAGCCGTGAAAAAGATGAAAGCGCTTAACCCGCATGC
TATCTATTTTTGCGATCCGGTAATGGGCCACCCTGAAAAAGGTTGTATTGTGTCGCCCGGTGTACAGGAGTTCTTAAAAA
CTCAAGCTTTGGCTGCAGCCGACATTATAGCGCCTAACCTGTTAGAGCTTGAGACATTAACGGATACAGAACTGCATAAT
CTCGATGAAGTGATTAACGCTTGTGAATGCTTGCTAGAAAAAGGGCTTGAGATGGTAGTGGTGAAGCACCTTGCTAAGGC
CGCCACTTGCCAAGAACAGTTTGAGATGCTGCTGGTGACAAAGACAGGCAGTTACTTAGTCTCGCGTCCTTTATATGAAT
TTGAAAAACAACCTGTGGGCGTCGGTGATTTAATCAGTGGCTTGATGTTAGCTAACCTGCAAGCAGGTTTTAGCCCGGTA
GACGCCTTTGAGCGCACTAATGCCTCAGTCGACGCCGTGTTATTGGAGACCTTTAACCAAGGCGCTTATGAGCTGCAATT
AATCGCCGCTCAAGATGCCATAGCATCACCGACAATTAAGCAGCAGGCTAAACGAGTTAACTAA

Upstream 100 bases:

>100_bases
GCCTAATTGGTATAATCGTTAAAAATCTCTGCTAGCTGTCAATAAACGGCAATAGAGCACCCTCAATCAACATCGCTAAT
AAAATTAAAGGTAGTGACCA

Downstream 100 bases:

>100_bases
TTCAAGTTTATTCGTATAGAAATTAATAGGCGGAATGTAATGAGCCTGCCCATCCATGGGCGGGCCTTTCCTTAGCTTTA
AAAGAAGTACCTAGCTCCTA

Product: pyridoxal kinase

Products: NA

Alternate protein names: PM kinase [H]

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWAGMIMPAGQITELVQGLDNIGQLQTCDALL
SGYLGSAEQGIEITAAVKKMKALNPHAIYFCDPVMGHPEKGCIVSPGVQEFLKTQALAAADIIAPNLLELETLTDTELHN
LDEVINACECLLEKGLEMVVVKHLAKAATCQEQFEMLLVTKTGSYLVSRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
DAFERTNASVDAVLLETFNQGAYELQLIAAQDAIASPTIKQQAKRVN

Sequences:

>Translated_287_residues
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWAGMIMPAGQITELVQGLDNIGQLQTCDALL
SGYLGSAEQGIEITAAVKKMKALNPHAIYFCDPVMGHPEKGCIVSPGVQEFLKTQALAAADIIAPNLLELETLTDTELHN
LDEVINACECLLEKGLEMVVVKHLAKAATCQEQFEMLLVTKTGSYLVSRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
DAFERTNASVDAVLLETFNQGAYELQLIAAQDAIASPTIKQQAKRVN
>Mature_287_residues
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWAGMIMPAGQITELVQGLDNIGQLQTCDALL
SGYLGSAEQGIEITAAVKKMKALNPHAIYFCDPVMGHPEKGCIVSPGVQEFLKTQALAAADIIAPNLLELETLTDTELHN
LDEVINACECLLEKGLEMVVVKHLAKAATCQEQFEMLLVTKTGSYLVSRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
DAFERTNASVDAVLLETFNQGAYELQLIAAQDAIASPTIKQQAKRVN

Specific function: Phosphorylates B6 vitamers; functions in a salvage pathway. Uses pyridoxamine [H]

COG id: COG2240

COG function: function code H; Pyridoxal/pyridoxine/pyridoxamine kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxine kinase family [H]

Homologues:

Organism=Homo sapiens, GI4505701, Length=306, Percent_Identity=29.7385620915033, Blast_Score=127, Evalue=2e-29,
Organism=Escherichia coli, GI1787924, Length=278, Percent_Identity=56.4748201438849, Blast_Score=320, Evalue=7e-89,
Organism=Escherichia coli, GI1788758, Length=264, Percent_Identity=29.5454545454545, Blast_Score=105, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17507759, Length=293, Percent_Identity=31.0580204778157, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17507757, Length=303, Percent_Identity=30.3630363036304, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320806, Length=235, Percent_Identity=34.468085106383, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324354, Length=180, Percent_Identity=32.2222222222222, Blast_Score=83, Evalue=4e-17,
Organism=Drosophila melanogaster, GI45553007, Length=311, Percent_Identity=32.1543408360129, Blast_Score=138, Evalue=4e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013749
- InterPro:   IPR004625 [H]

Pfam domain/function: PF08543 Phos_pyr_kin [H]

EC number: =2.7.1.35 [H]

Molecular weight: Translated: 31108; Mature: 31108

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWAGMIMPAGQI
CCCHHEECCEEEEEECCCCCCCCHHHHCCCEEECCCEEEECCCCCHHCCCCCCCCCCHHH
TELVQGLDNIGQLQTCDALLSGYLGSAEQGIEITAAVKKMKALNPHAIYFCDPVMGHPEK
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCC
GCIVSPGVQEFLKTQALAAADIIAPNLLELETLTDTELHNLDEVINACECLLEKGLEMVV
CCEECCCHHHHHHHHHHHHHHHHCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHCCHHHHH
VKHLAKAATCQEQFEMLLVTKTGSYLVSRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
HHHHHHHHHHHHHHHEEEEEECCCHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCHH
DAFERTNASVDAVLLETFNQGAYELQLIAAQDAIASPTIKQQAKRVN
HHHHHCCCCHHHHHHHHHCCCCEEEEEEEECHHHCCCHHHHHHHCCC
>Mature Secondary Structure
MKRILSIQSHVVFGCAGNSSAVFPMRRLGMEVWPINTVQFSNHTQYAQGWAGMIMPAGQI
CCCHHEECCEEEEEECCCCCCCCHHHHCCCEEECCCEEEECCCCCHHCCCCCCCCCCHHH
TELVQGLDNIGQLQTCDALLSGYLGSAEQGIEITAAVKKMKALNPHAIYFCDPVMGHPEK
HHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCEEEEECCCCCCCCC
GCIVSPGVQEFLKTQALAAADIIAPNLLELETLTDTELHNLDEVINACECLLEKGLEMVV
CCEECCCHHHHHHHHHHHHHHHHCCCCEEEHHCCCHHHHHHHHHHHHHHHHHHCCHHHHH
VKHLAKAATCQEQFEMLLVTKTGSYLVSRPLYEFEKQPVGVGDLISGLMLANLQAGFSPV
HHHHHHHHHHHHHHHEEEEEECCCHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHCCCCHH
DAFERTNASVDAVLLETFNQGAYELQLIAAQDAIASPTIKQQAKRVN
HHHHHCCCCHHHHHHHHHCCCCEEEEEEEECHHHCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA