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The map label for this gene is murA [H]

Identifier: 157963417

GI number: 157963417

Start: 4397724

End: 4398986

Strand: Reverse

Name: murA [H]

Synonym: Spea_3603

Alternate gene names: 157963417

Gene position: 4398986-4397724 (Counterclockwise)

Preceding gene: 157963418

Following gene: 157963416

Centisome position: 85.01

GC content: 48.14

Gene sequence:

>1263_bases
GTGGATAAATTAAAAATTGAAGCAAGTGGTGCACTTGCTGGAAACGTGGTTATCTCAGGTGCTAAAAATGCCGCATTGCC
TATTTTAATGGCAGGTGTGCTGGCCGAGACAGACTTCAATGTTTCTAACGTACCGAATTTAAGAGATGTGAACACTAGCT
GCGAATTATTACGCTGTTTAGGCGCCGAAGTGACTCGCTCTGGCACTGACAAGGTGTGTATCTCTACGACTAACCTTAAT
GAGTTTTGTGCGCCGTATGATTTGGTTAAAACCATGCGTGCATCGATTCTTATTTTAGGTCCGCTACTTGCGCGCTATGG
CACCGCCGATGTGTCTTTGCCGGGTGGCTGCGCGATTGGTGCCCGTCCTGTTAACTTGCATCTGCAAGGTCTTGAACAGA
TGGGCGCACAAATTGAAGTGCAAGAGGGTTACATTAAGGCTCGTGTTGATGGGCGTTTGAAAGGCGCACATATCTTTATG
GATATGATCAGCGTTGGTGCGACAGAAAACTTGCTAATGGCAGCATCATTAGCCGATGGTGAAACCATTATCGAAAACGC
TGCTCGTGAGCCTGAAGTGGTCGATTTGGCAAACTGCTTAATTGCAATGGGCGCAAAAATTGAAGGCGCGGGTACCGATA
CTGTGCGCATTCAGGGGGTAGAGTCATTGCAAGGCTGTGATTACCGAGTGATGCCTGACCGCATCGAAACTGGTAGCTTC
TTAGTGGCAGCTGCGGTTACTCGCGGTAAGATCCGTTGTACGAAAGCAGACCCTAAGTCGCTTGAAGCGGTATTAGCTAA
GCTTGAAGACGCTGGTGCAAACATCACCACGGGTGATGACTGGATTGAGCTAGATATGCAGGGCAAGCGCCCTAAAGCAG
TAAATATCAAGACCGTGGCTTACCCAGGTTTTCCAACCGATATGCAGGCGCAGTTCTGCGTGCTTAACGCTCTCGCCGAA
GGCACTGCAACGATTACCGAAACCATTTTCGAAAACCGCTTTATGCATGTACCAGAGTTAAGCCGTATGGGCGCAACGAT
GGAGCTGGAAGGTAATACTTGTATTATTCACGGTATTGAAAGGCTAAATGGGGCACAGGTGATGGCAACGGATCTACGTG
CGTCAGCAAGCCTTGTGATTGCTGGCCTAGTGGCAGAAGGCACGACAATTGTCGATCGTATTTACCACTTAGATCGTGGT
TACGAGCATATTGAAGACAAATTTAAAGGCTTAGGCGGACACGTTGAACGTGTTAAGTCATAG

Upstream 100 bases:

>100_bases
TAGCGGTGAGTTACACGCTATTACGATTAATGCCTTCACGCCTACACAGTGGAAGCGTGAAAAAGTCTTTAATATGTAAT
CGCGGATTTAGAGAGTTAAA

Downstream 100 bases:

>100_bases
CTTTTAAGCCCCTACTAATAAAAAAGCCATTTAAGTGTATTCACTTAAGTGGCTTTTTTGTTTTATGAACTAGCGCAAAT
TGCTGAGTTATAAAATCAGA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 420; Mature: 420

Protein sequence:

>420_residues
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCLGAEVTRSGTDKVCISTTNLN
EFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLQGLEQMGAQIEVQEGYIKARVDGRLKGAHIFM
DMISVGATENLLMAASLADGETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYRVMPDRIETGSF
LVAAAVTRGKIRCTKADPKSLEAVLAKLEDAGANITTGDDWIELDMQGKRPKAVNIKTVAYPGFPTDMQAQFCVLNALAE
GTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIERLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRG
YEHIEDKFKGLGGHVERVKS

Sequences:

>Translated_420_residues
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCLGAEVTRSGTDKVCISTTNLN
EFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLQGLEQMGAQIEVQEGYIKARVDGRLKGAHIFM
DMISVGATENLLMAASLADGETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYRVMPDRIETGSF
LVAAAVTRGKIRCTKADPKSLEAVLAKLEDAGANITTGDDWIELDMQGKRPKAVNIKTVAYPGFPTDMQAQFCVLNALAE
GTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIERLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRG
YEHIEDKFKGLGGHVERVKS
>Mature_420_residues
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCLGAEVTRSGTDKVCISTTNLN
EFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIGARPVNLHLQGLEQMGAQIEVQEGYIKARVDGRLKGAHIFM
DMISVGATENLLMAASLADGETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYRVMPDRIETGSF
LVAAAVTRGKIRCTKADPKSLEAVLAKLEDAGANITTGDDWIELDMQGKRPKAVNIKTVAYPGFPTDMQAQFCVLNALAE
GTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIERLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRG
YEHIEDKFKGLGGHVERVKS

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=419, Percent_Identity=67.5417661097852, Blast_Score=586, Evalue=1e-169,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44775; Mature: 44775

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCL
CCCEEEEECCCEECCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
GAEVTRSGTDKVCISTTNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIG
CCHHHCCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
ARPVNLHLQGLEQMGAQIEVQEGYIKARVDGRLKGAHIFMDMISVGATENLLMAASLADG
CEEEEEEEHHHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCCC
ETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYRVMPDRIETGSF
HHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECHHCCCCCEEECCCCCCCCCE
LVAAAVTRGKIRCTKADPKSLEAVLAKLEDAGANITTGDDWIELDMQGKRPKAVNIKTVA
EEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEEEE
YPGFPTDMQAQFCVLNALAEGTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIE
ECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCEEEEEEHH
RLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRGYEHIEDKFKGLGGHVERVKS
HCCCCEEEEEHHHCCCEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MDKLKIEASGALAGNVVISGAKNAALPILMAGVLAETDFNVSNVPNLRDVNTSCELLRCL
CCCEEEEECCCEECCEEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHH
GAEVTRSGTDKVCISTTNLNEFCAPYDLVKTMRASILILGPLLARYGTADVSLPGGCAIG
CCHHHCCCCCEEEEEECCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEC
ARPVNLHLQGLEQMGAQIEVQEGYIKARVDGRLKGAHIFMDMISVGATENLLMAASLADG
CEEEEEEEHHHHHCCCEEEEECCEEEEEECCCCCHHHHHHHHHHCCCCCCEEEEEECCCC
ETIIENAAREPEVVDLANCLIAMGAKIEGAGTDTVRIQGVESLQGCDYRVMPDRIETGSF
HHHHHHCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECHHCCCCCEEECCCCCCCCCE
LVAAAVTRGKIRCTKADPKSLEAVLAKLEDAGANITTGDDWIELDMQGKRPKAVNIKTVA
EEEEEECCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEEEEE
YPGFPTDMQAQFCVLNALAEGTATITETIFENRFMHVPELSRMGATMELEGNTCIIHGIE
ECCCCCCCCHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCEEEEEEHH
RLNGAQVMATDLRASASLVIAGLVAEGTTIVDRIYHLDRGYEHIEDKFKGLGGHVERVKS
HCCCCEEEEEHHHCCCEEEEEEHHHCCHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA