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The map label for this gene is dsbD [H]

Identifier: 157963017

GI number: 157963017

Start: 3921955

End: 3924012

Strand: Reverse

Name: dsbD [H]

Synonym: Spea_3200

Alternate gene names: 157963017

Gene position: 3924012-3921955 (Counterclockwise)

Preceding gene: 157963018

Following gene: 157963016

Centisome position: 75.83

GC content: 47.76

Gene sequence:

>2058_bases
GTGAAAATATTAAAACAGATTATTCTGGTGTGTTTATTAGCATTAGCTAATCCGGTATTTGCCCAGTCAACAGGCTGGCT
AGAGAACCCTAATCACCCGCCAGTAAAAGTGAGGTTTATGCTCACGGGGGAGGTCGATAAGGCCAGTAACACAGTGCCTG
GGGTGCTGGAAGTTGAGCTCGATGGTGAGTGGAAAACCTATTGGCGTAGCCCTGGTGAGGGCGGCATTGCGCCGAGTATC
GACTGGAGTGGCTCAAGCAACTTAAACCAAGTCGATTGGGACTGGCCTGCACCTGAGCAATTCTCGCTACTTGGTCTACA
AACCTTTGGTTATCACCATGAGGCTGCTTTTCCTATGCAGCTGCAACTCGATGATACAAATAAGCCCACTCATTTACAGG
GTAAATTTACCCTGTCGTCATGCACTAATGTGTGTGTATTAACAGATTATGAGCTTAACCTAGATATCGACCCCACTGCA
TTAAATGCTGATGTTGACGCCATGTTTGCCTACAACAAAGCCGTGTCTAAAGTACCGGTTAAATTGCAGCGAGAAGATGT
CACGCTTGGTTGGGATGTAAAAGCGCAGCAACTGCAAGTGGAGATGGATGATACTGGTTGGAGCATGCCAAAATTTATTA
TCGATGGTGAGCCTGATACCACCTTTAAGTTTGTGCGGTTCGAGCGTTATGACACCGATAGCGGCCAGCAAAAGCTACGA
GCTATCTTTGATGCAACAAGCTGGCTAGGTGAGCCTGAGCTCATTGGTAAGTCGTTAAACCTTACGGTGATGGATAAAGA
GCAGGCATTAGAGTTTGTTGCAAACGTTAGCGGCATCACCATTCAAGCTAGCGGCCATTCGCTACTGAGCATGCTAGTTA
TCGCGCTATTAGGTGGCCTGATTTTAAATGTCATGCCCTGCGTGTTACCGGTTCTAGGCATGAAATTAAGTTCAGTGATA
GCGGCGCCAAATCTACAAGTTAAGCAAATCCGCCAGCAGTTTATCGCCTCTGCCTTGGGGATTTTAGTGTCATTTTGGTT
GCTTGCAGGATTTATCTTAATCCTTAAATTTACCGGGCAGGCGATAGGTTGGGGGGTACAGTTCCAAAACCCTTGGTTTA
TTGGTTTTATGGCGGTAGTTACCGCGATATTTGCCATCAATATGTTGGGCGCGTTTGAGATTAACTTACCATCGAGTTTG
CAAACTAAGTTGGCAACCACTGGCGGTAATGATCACCGCGGACATTTCTTGCAAGGCATGTTTGCGACCTTACTTGCGAC
GCCGTGCAGCGCACCATTTCTTGGTACTGCGGTGGCCTTCGCCCTTGGCGCTGACGTATTGAGTCTATTTGTTATCTTTA
GCGCCTTAGCGCTAGGCATGGCGTTACCTTGGTTGCTAGTGGCTGCGTTTCCTCAAGTTGCGCGTTATTTCCCTAAACCG
GGCCGCTGGATGAGTGTGGTTAAAGTGGTGTTCTCCGGCCTCTTGGTACTGACTAGTCTGTGGCTACTTAGTCTGTTAGC
CAACTTTATACCGGCTGCTTACTTGTGGATTGCGGCTGGCACTTTAGTACTGTTGTTTTTAGTGTTGATGGCCAAAGTTC
AAGGAAAAGCTGCTGTTATCGCCAGTGTCAGCGTCGGAATTATGGTGATAGCCGTTGGGGCATTTTCTACATCTAACAGG
TGGGCGCAGCCGTTACCAACCGACTTAGAATGGCATATGTTGAATGAGCCTGAAATCGCGAGACAAGTTGCGGCAGGCAA
GACCGTATTTGTCGATGTGACTGCCGATTGGTGTATTACCTGTAAAGCCAACAAGGTTGGGGTGATCTTACAAGATCCGG
TATACAGCGAATTAAAGGCTGACAATATCGTGTTGATGGAGGGGGAGTGGACTAAACCATCGAAGCCAATAACCGAGTAT
TTACAGAGCCATAACCGCTTTGGTGTGCCCTTTAACGTGGTTTACGGCCCGAATGCGCCAGAGGGGATTGCACTGCCAGT
GATCTTGTCTGCCAGCGATGTTATCGATGCTATCAATGTGGCCTCGGTAAGGTTCTAA

Upstream 100 bases:

>100_bases
AAATTGGGCCTAACCCCTAACATAAACCGTTTATTAATCGCTAAGCCAATAGCTTAAAAGTGCTGGATTGGTGGCGAGCC
GTTTTTGCGGAGAAAGAAAA

Downstream 100 bases:

>100_bases
TCCAAATTAACACTTGCAAGCGCTAAATACGAAGCTAATAGCGCCAAATGTAAGTGTTAAAGAAATAGTTAAGAGCGCTG
CTATTGGCAGCGCTAAGAGA

Product: cytochrome C biogenesis transmembrane protein

Products: NA

Alternate protein names: Protein-disulfide reductase; Disulfide reductase [H]

Number of amino acids: Translated: 685; Mature: 685

Protein sequence:

>685_residues
MKILKQIILVCLLALANPVFAQSTGWLENPNHPPVKVRFMLTGEVDKASNTVPGVLEVELDGEWKTYWRSPGEGGIAPSI
DWSGSSNLNQVDWDWPAPEQFSLLGLQTFGYHHEAAFPMQLQLDDTNKPTHLQGKFTLSSCTNVCVLTDYELNLDIDPTA
LNADVDAMFAYNKAVSKVPVKLQREDVTLGWDVKAQQLQVEMDDTGWSMPKFIIDGEPDTTFKFVRFERYDTDSGQQKLR
AIFDATSWLGEPELIGKSLNLTVMDKEQALEFVANVSGITIQASGHSLLSMLVIALLGGLILNVMPCVLPVLGMKLSSVI
AAPNLQVKQIRQQFIASALGILVSFWLLAGFILILKFTGQAIGWGVQFQNPWFIGFMAVVTAIFAINMLGAFEINLPSSL
QTKLATTGGNDHRGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFVIFSALALGMALPWLLVAAFPQVARYFPKP
GRWMSVVKVVFSGLLVLTSLWLLSLLANFIPAAYLWIAAGTLVLLFLVLMAKVQGKAAVIASVSVGIMVIAVGAFSTSNR
WAQPLPTDLEWHMLNEPEIARQVAAGKTVFVDVTADWCITCKANKVGVILQDPVYSELKADNIVLMEGEWTKPSKPITEY
LQSHNRFGVPFNVVYGPNAPEGIALPVILSASDVIDAINVASVRF

Sequences:

>Translated_685_residues
MKILKQIILVCLLALANPVFAQSTGWLENPNHPPVKVRFMLTGEVDKASNTVPGVLEVELDGEWKTYWRSPGEGGIAPSI
DWSGSSNLNQVDWDWPAPEQFSLLGLQTFGYHHEAAFPMQLQLDDTNKPTHLQGKFTLSSCTNVCVLTDYELNLDIDPTA
LNADVDAMFAYNKAVSKVPVKLQREDVTLGWDVKAQQLQVEMDDTGWSMPKFIIDGEPDTTFKFVRFERYDTDSGQQKLR
AIFDATSWLGEPELIGKSLNLTVMDKEQALEFVANVSGITIQASGHSLLSMLVIALLGGLILNVMPCVLPVLGMKLSSVI
AAPNLQVKQIRQQFIASALGILVSFWLLAGFILILKFTGQAIGWGVQFQNPWFIGFMAVVTAIFAINMLGAFEINLPSSL
QTKLATTGGNDHRGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFVIFSALALGMALPWLLVAAFPQVARYFPKP
GRWMSVVKVVFSGLLVLTSLWLLSLLANFIPAAYLWIAAGTLVLLFLVLMAKVQGKAAVIASVSVGIMVIAVGAFSTSNR
WAQPLPTDLEWHMLNEPEIARQVAAGKTVFVDVTADWCITCKANKVGVILQDPVYSELKADNIVLMEGEWTKPSKPITEY
LQSHNRFGVPFNVVYGPNAPEGIALPVILSASDVIDAINVASVRF
>Mature_685_residues
MKILKQIILVCLLALANPVFAQSTGWLENPNHPPVKVRFMLTGEVDKASNTVPGVLEVELDGEWKTYWRSPGEGGIAPSI
DWSGSSNLNQVDWDWPAPEQFSLLGLQTFGYHHEAAFPMQLQLDDTNKPTHLQGKFTLSSCTNVCVLTDYELNLDIDPTA
LNADVDAMFAYNKAVSKVPVKLQREDVTLGWDVKAQQLQVEMDDTGWSMPKFIIDGEPDTTFKFVRFERYDTDSGQQKLR
AIFDATSWLGEPELIGKSLNLTVMDKEQALEFVANVSGITIQASGHSLLSMLVIALLGGLILNVMPCVLPVLGMKLSSVI
AAPNLQVKQIRQQFIASALGILVSFWLLAGFILILKFTGQAIGWGVQFQNPWFIGFMAVVTAIFAINMLGAFEINLPSSL
QTKLATTGGNDHRGHFLQGMFATLLATPCSAPFLGTAVAFALGADVLSLFVIFSALALGMALPWLLVAAFPQVARYFPKP
GRWMSVVKVVFSGLLVLTSLWLLSLLANFIPAAYLWIAAGTLVLLFLVLMAKVQGKAAVIASVSVGIMVIAVGAFSTSNR
WAQPLPTDLEWHMLNEPEIARQVAAGKTVFVDVTADWCITCKANKVGVILQDPVYSELKADNIVLMEGEWTKPSKPITEY
LQSHNRFGVPFNVVYGPNAPEGIALPVILSASDVIDAINVASVRF

Specific function: Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a

COG id: COG4232

COG function: function code OC; Thiol:disulfide interchange protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1790578, Length=381, Percent_Identity=27.5590551181102, Blast_Score=103, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834
- InterPro:   IPR022910
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF02683 DsbD; PF00085 Thioredoxin [H]

EC number: =1.8.1.8 [H]

Molecular weight: Translated: 74730; Mature: 74730

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILKQIILVCLLALANPVFAQSTGWLENPNHPPVKVRFMLTGEVDKASNTVPGVLEVEL
CHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEE
DGEWKTYWRSPGEGGIAPSIDWSGSSNLNQVDWDWPAPEQFSLLGLQTFGYHHEAAFPMQ
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCEEE
LQLDDTNKPTHLQGKFTLSSCTNVCVLTDYELNLDIDPTALNADVDAMFAYNKAVSKVPV
EEECCCCCCCEEEEEEEHHCCCCEEEEEEEEEEECCCCCEECCCHHHHHHHHHHHHHCCC
KLQREDVTLGWDVKAQQLQVEMDDTGWSMPKFIIDGEPDTTFKFVRFERYDTDSGQQKLR
EEEECCEEEECCCEEEEEEEEECCCCCCCCCEEECCCCCCEEEEEEEEECCCCCHHHHHH
AIFDATSWLGEPELIGKSLNLTVMDKEQALEFVANVSGITIQASGHSLLSMLVIALLGGL
HHHHHHHHCCCHHHCCCCCEEEEECHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
ILNVMPCVLPVLGMKLSSVIAAPNLQVKQIRQQFIASALGILVSFWLLAGFILILKFTGQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AIGWGVQFQNPWFIGFMAVVTAIFAINMLGAFEINLPSSLQTKLATTGGNDHRGHFLQGM
HHEECEEECCCHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHEECCCCCCCCHHHHHH
FATLLATPCSAPFLGTAVAFALGADVLSLFVIFSALALGMALPWLLVAAFPQVARYFPKP
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GRWMSVVKVVFSGLLVLTSLWLLSLLANFIPAAYLWIAAGTLVLLFLVLMAKVQGKAAVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ASVSVGIMVIAVGAFSTSNRWAQPLPTDLEWHMLNEPEIARQVAAGKTVFVDVTADWCIT
EHHHHCEEEEEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHCCCEEEEEECCCEEEE
CKANKVGVILQDPVYSELKADNIVLMEGEWTKPSKPITEYLQSHNRFGVPFNVVYGPNAP
EECCCEEEEECCCCHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCC
EGIALPVILSASDVIDAINVASVRF
CCEEEEEEECHHHHHHHHHHHEECC
>Mature Secondary Structure
MKILKQIILVCLLALANPVFAQSTGWLENPNHPPVKVRFMLTGEVDKASNTVPGVLEVEL
CHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCEEEEEE
DGEWKTYWRSPGEGGIAPSIDWSGSSNLNQVDWDWPAPEQFSLLGLQTFGYHHEAAFPMQ
CCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHCCCCCCCCCEEE
LQLDDTNKPTHLQGKFTLSSCTNVCVLTDYELNLDIDPTALNADVDAMFAYNKAVSKVPV
EEECCCCCCCEEEEEEEHHCCCCEEEEEEEEEEECCCCCEECCCHHHHHHHHHHHHHCCC
KLQREDVTLGWDVKAQQLQVEMDDTGWSMPKFIIDGEPDTTFKFVRFERYDTDSGQQKLR
EEEECCEEEECCCEEEEEEEEECCCCCCCCCEEECCCCCCEEEEEEEEECCCCCHHHHHH
AIFDATSWLGEPELIGKSLNLTVMDKEQALEFVANVSGITIQASGHSLLSMLVIALLGGL
HHHHHHHHCCCHHHCCCCCEEEEECHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHH
ILNVMPCVLPVLGMKLSSVIAAPNLQVKQIRQQFIASALGILVSFWLLAGFILILKFTGQ
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
AIGWGVQFQNPWFIGFMAVVTAIFAINMLGAFEINLPSSLQTKLATTGGNDHRGHFLQGM
HHEECEEECCCHHHHHHHHHHHHHHHHHHCEEEECCCCHHHHHHEECCCCCCCCHHHHHH
FATLLATPCSAPFLGTAVAFALGADVLSLFVIFSALALGMALPWLLVAAFPQVARYFPKP
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GRWMSVVKVVFSGLLVLTSLWLLSLLANFIPAAYLWIAAGTLVLLFLVLMAKVQGKAAVI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
ASVSVGIMVIAVGAFSTSNRWAQPLPTDLEWHMLNEPEIARQVAAGKTVFVDVTADWCIT
EHHHHCEEEEEEECCCCCCCCCCCCCCCCCEEECCCHHHHHHHHCCCEEEEEECCCEEEE
CKANKVGVILQDPVYSELKADNIVLMEGEWTKPSKPITEYLQSHNRFGVPFNVVYGPNAP
EECCCEEEEECCCCHHHHCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCEEEEEECCCCC
EGIALPVILSASDVIDAINVASVRF
CCEEEEEEECHHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA