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The map label for this gene is deoD [H]

Identifier: 157962863

GI number: 157962863

Start: 3735219

End: 3735929

Strand: Reverse

Name: deoD [H]

Synonym: Spea_3045

Alternate gene names: 157962863

Gene position: 3735929-3735219 (Counterclockwise)

Preceding gene: 157962864

Following gene: 157962861

Centisome position: 72.2

GC content: 44.44

Gene sequence:

>711_bases
ATGGCTACACCACACATTAATGCCGTAGACGGTGCATTTGGCGATACAGTTCTATTTCCAGGCGATCCACTACGTGCAAA
GTACATTGCTGAAACTTTCCTAGAGAACGTTGAGCAAGTAACTGACGTACGTAACATGCTAGGTTTTACTGGTACTTACA
AAGGCGTTCGTATCTCAGTTATGGGTTCAGGCATGGGTATCCCATCTTGCTCAATCTATGCAACTGAGTTGATCAAAGAT
TACGGTGTTAAGAACCTAATCCGCGTGGGTACTTGTGGCGCAATCAGCACTGACGTTAAAGTACGTGACGTGATCATCGG
TATGGGTGCTTGTACTGATTCACAAACTAACCGTTTACGCTTCCGTGGCCAAGACTTCGCAGCTATCTGTGATTACGGTC
TACTAAGCGCAGTCGTTAAAGCTGCTGACGTAAAAGGTATTAAGTACCGCGTAGGTAACGTTTTCTCTGCTGATCTATTC
TACACGCCAGATCCAGAAATGTTTGACGTGATGGAAAAGATGGACGTACTAGGTGTCGAAATGGAAGCTGCTGGTCTATA
CGGCGTAGCAAAAGAGTTCGGTGCTAAGGCGTTATGTGTTGTAACTGTATCTGATCATATCCGTACAGGTGAAAAGACGA
CTTCTGATGAGCGTCAAACAACATTCAACGAAATGATTGAAATGACACTAGAAGCTGCGATTACTCTGTAA

Upstream 100 bases:

>100_bases
AAGCTGTAAATAAATTTGAATTTGGTGGCTCAGATTGAGCCACTAGTAAACAAGACTAAGTTGATACAACGGTCTAAAAA
TATAAATAGGGGTTATTCTG

Downstream 100 bases:

>100_bases
TTGTAACGCTTTGCAGTCACTGGCTGCGGTGTAAAAAAAACGGACGCTTATGCGTCCGTTTTTGTTTTATGACTCGTTAA
TTAATCTTCATCTTTGGGAT

Product: purine nucleoside phosphorylase

Products: NA

Alternate protein names: PNP 2 [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MATPHINAVDGAFGDTVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGVRISVMGSGMGIPSCSIYATELIKD
YGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQTNRLRFRGQDFAAICDYGLLSAVVKAADVKGIKYRVGNVFSADLF
YTPDPEMFDVMEKMDVLGVEMEAAGLYGVAKEFGAKALCVVTVSDHIRTGEKTTSDERQTTFNEMIEMTLEAAITL

Sequences:

>Translated_236_residues
MATPHINAVDGAFGDTVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGVRISVMGSGMGIPSCSIYATELIKD
YGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQTNRLRFRGQDFAAICDYGLLSAVVKAADVKGIKYRVGNVFSADLF
YTPDPEMFDVMEKMDVLGVEMEAAGLYGVAKEFGAKALCVVTVSDHIRTGEKTTSDERQTTFNEMIEMTLEAAITL
>Mature_235_residues
ATPHINAVDGAFGDTVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGVRISVMGSGMGIPSCSIYATELIKDY
GVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQTNRLRFRGQDFAAICDYGLLSAVVKAADVKGIKYRVGNVFSADLFY
TPDPEMFDVMEKMDVLGVEMEAAGLYGVAKEFGAKALCVVTVSDHIRTGEKTTSDERQTTFNEMIEMTLEAAITL

Specific function: Cleavage Of Guanosine Or Inosine To Respective Bases And Sugar-1-Phosphate Molecules. [C]

COG id: COG0813

COG function: function code F; Purine-nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family [H]

Homologues:

Organism=Escherichia coli, GI1790844, Length=234, Percent_Identity=69.6581196581197, Blast_Score=341, Evalue=2e-95,
Organism=Escherichia coli, GI1790265, Length=234, Percent_Identity=28.6324786324786, Blast_Score=78, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004402
- InterPro:   IPR018017
- InterPro:   IPR018016
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =2.4.2.1 [H]

Molecular weight: Translated: 25562; Mature: 25430

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS01232 PNP_UDP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPHINAVDGAFGDTVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGVRISV
CCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
MGSGMGIPSCSIYATELIKDYGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQTNRLR
EECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCEEE
FRGQDFAAICDYGLLSAVVKAADVKGIKYRVGNVFSADLFYTPDPEMFDVMEKMDVLGVE
ECCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEECEEECCCCHHHHHHHHHHHHCCE
MEAAGLYGVAKEFGAKALCVVTVSDHIRTGEKTTSDERQTTFNEMIEMTLEAAITL
EHHHHHHHHHHHHCCCEEEEEEECCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ATPHINAVDGAFGDTVLFPGDPLRAKYIAETFLENVEQVTDVRNMLGFTGTYKGVRISV
CCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEE
MGSGMGIPSCSIYATELIKDYGVKNLIRVGTCGAISTDVKVRDVIIGMGACTDSQTNRLR
EECCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCCCCCCCEEEEEEEECCCCCCCCCCEEE
FRGQDFAAICDYGLLSAVVKAADVKGIKYRVGNVFSADLFYTPDPEMFDVMEKMDVLGVE
ECCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCEEEECEEECCCCHHHHHHHHHHHHCCE
MEAAGLYGVAKEFGAKALCVVTVSDHIRTGEKTTSDERQTTFNEMIEMTLEAAITL
EHHHHHHHHHHHHCCCEEEEEEECCHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]