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The map label for this gene is serB [H]

Identifier: 157962861

GI number: 157962861

Start: 3732940

End: 3733947

Strand: Reverse

Name: serB [H]

Synonym: Spea_3043

Alternate gene names: 157962861

Gene position: 3733947-3732940 (Counterclockwise)

Preceding gene: 157962863

Following gene: 157962860

Centisome position: 72.16

GC content: 46.92

Gene sequence:

>1008_bases
ATGGAAAGTTTGAGTCAATCGACTGTTTTTGCTTGGTTAAGTACCGAAGGTAGCATGTCTTTTACTGCTGGTGAACAAAT
CTATTCACGCCATCTTGAAGCTGATTATCCTAAAGGTTTTTCTCGTTATAGAATTTTATTCGCTGAGTTAGATAGTCTTA
GCGAAGACTTATTGCAGGTGACTCATACTAGCTTAAATGTCTGGCTTGCATCCCTCGATGGCAACCTAAGTTTGGCATTG
ATCGTGCGTGACTGCGGTTTAACCTGTATCGAAGTTTGCACCTCAATACCTTTGACCAGCGTACAAATAGCCGCAATTAG
TGAGACGGTGTCCCTAGAATTGTTTGAGTTAACCGTCGATGCACCACAGTTAAGTCAAGCGGGGCTGTTGGTGATGGACA
TGGACTCAACCGCAATTGAAATCGAGTGTATCGATGAATTAGCCGAAATGGCTGGAGTAGGGCCTGCGGTTGCGGAAGTG
ACAGAACTCGCCATGCAAGGCGAACTCGACTTTGAACAGAGTCTTAGGGCGCGGGTCGCCAAGCTTAAAGGCGCCGATGC
CGAAATTATCGATACCCTATGTGCCAAGCTGCCACTCATGCCGGGTCTTAAGGAGATGATTGCAGAGCTGCAGAGTCATG
GCTGGCGCACAGTGGTTGCTTCAGGCGGATTTACCCCCTTTGTAAACCACCTTAAACAGTTATTGGCGCTAGATGCCGCT
TTTGCGAATAAGCTAGATATCGAGAGCGGCAAACTACTTGGCACTGTGTCTGGTCAAGTGGTTGATGCGCAATACAAGGC
TGATACCGTGCTTAAGTGCGCCAAGCAGTGGCAGATAGCGGCAGGGCAAAGAGTAGCGATAGGCGATGGCGCGAATGATA
TCCCGATGATTAACACTGCCGACTTTGGTATTGCTTATCATGCTAAACCTAAATTGGCTCAAGCTGCTGATGTTAGTATT
AATCGACTTAACCTTAAAGCCTTACCTTACTTGTTTCAACGCACTTAG

Upstream 100 bases:

>100_bases
TTAGGCCTTTTAAATAGAACACTGAAACCCTTAATTTATTGTGTACTCACCTAATCATAATTGATTATGTCTGTGCTCGG
TAGTTGGAGAGCCATAACTA

Downstream 100 bases:

>100_bases
GCTCAAAATATAGGTTCTATATATAGGTTCTACATATAGGATTTACAGGCTAGGCTATAGAGAATAAGTATTCCTCCTTA
GGTTACTCTGACCTGTTTTG

Product: phosphoserine phosphatase SerB

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MESLSQSTVFAWLSTEGSMSFTAGEQIYSRHLEADYPKGFSRYRILFAELDSLSEDLLQVTHTSLNVWLASLDGNLSLAL
IVRDCGLTCIEVCTSIPLTSVQIAAISETVSLELFELTVDAPQLSQAGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEV
TELAMQGELDFEQSLRARVAKLKGADAEIIDTLCAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVNHLKQLLALDAA
FANKLDIESGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAAGQRVAIGDGANDIPMINTADFGIAYHAKPKLAQAADVSI
NRLNLKALPYLFQRT

Sequences:

>Translated_335_residues
MESLSQSTVFAWLSTEGSMSFTAGEQIYSRHLEADYPKGFSRYRILFAELDSLSEDLLQVTHTSLNVWLASLDGNLSLAL
IVRDCGLTCIEVCTSIPLTSVQIAAISETVSLELFELTVDAPQLSQAGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEV
TELAMQGELDFEQSLRARVAKLKGADAEIIDTLCAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVNHLKQLLALDAA
FANKLDIESGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAAGQRVAIGDGANDIPMINTADFGIAYHAKPKLAQAADVSI
NRLNLKALPYLFQRT
>Mature_335_residues
MESLSQSTVFAWLSTEGSMSFTAGEQIYSRHLEADYPKGFSRYRILFAELDSLSEDLLQVTHTSLNVWLASLDGNLSLAL
IVRDCGLTCIEVCTSIPLTSVQIAAISETVSLELFELTVDAPQLSQAGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEV
TELAMQGELDFEQSLRARVAKLKGADAEIIDTLCAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVNHLKQLLALDAA
FANKLDIESGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAAGQRVAIGDGANDIPMINTADFGIAYHAKPKLAQAADVSI
NRLNLKALPYLFQRT

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=196, Percent_Identity=32.6530612244898, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1790849, Length=204, Percent_Identity=57.3529411764706, Blast_Score=239, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI115534456, Length=192, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115534454, Length=192, Percent_Identity=29.1666666666667, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI115534458, Length=194, Percent_Identity=28.8659793814433, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6321647, Length=221, Percent_Identity=38.0090497737557, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24661601, Length=203, Percent_Identity=28.5714285714286, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 36154; Mature: 36154

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESLSQSTVFAWLSTEGSMSFTAGEQIYSRHLEADYPKGFSRYRILFAELDSLSEDLLQV
CCCCCCCEEEEEEECCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
THTSLNVWLASLDGNLSLALIVRDCGLTCIEVCTSIPLTSVQIAAISETVSLELFELTVD
HHHHEEEEEEECCCCEEEEEEEECCCCHHHHHHHCCCCCEEEEEEEHHHHEEEEEEEEEC
APQLSQAGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEVTELAMQGELDFEQSLRARVA
CCCCCCCCEEEEECCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
KLKGADAEIIDTLCAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVNHLKQLLALDAA
HHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
FANKLDIESGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAAGQRVAIGDGANDIPMINTA
HHCCCCCCCCCEEEECCCEEEECHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEECC
DFGIAYHAKPKLAQAADVSINRLNLKALPYLFQRT
CCCEEEECCCCCCHHHCCEEEEECHHHHHHHHHCC
>Mature Secondary Structure
MESLSQSTVFAWLSTEGSMSFTAGEQIYSRHLEADYPKGFSRYRILFAELDSLSEDLLQV
CCCCCCCEEEEEEECCCCEEECHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
THTSLNVWLASLDGNLSLALIVRDCGLTCIEVCTSIPLTSVQIAAISETVSLELFELTVD
HHHHEEEEEEECCCCEEEEEEEECCCCHHHHHHHCCCCCEEEEEEEHHHHEEEEEEEEEC
APQLSQAGLLVMDMDSTAIEIECIDELAEMAGVGPAVAEVTELAMQGELDFEQSLRARVA
CCCCCCCCEEEEECCCCEEEHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHH
KLKGADAEIIDTLCAKLPLMPGLKEMIAELQSHGWRTVVASGGFTPFVNHLKQLLALDAA
HHCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHH
FANKLDIESGKLLGTVSGQVVDAQYKADTVLKCAKQWQIAAGQRVAIGDGANDIPMINTA
HHCCCCCCCCCEEEECCCEEEECHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCEEECC
DFGIAYHAKPKLAQAADVSINRLNLKALPYLFQRT
CCCEEEECCCCCCHHHCCEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]