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The map label for this gene is 157961528

Identifier: 157961528

GI number: 157961528

Start: 2069591

End: 2070592

Strand: Reverse

Name: 157961528

Synonym: Spea_1703

Alternate gene names: NA

Gene position: 2070592-2069591 (Counterclockwise)

Preceding gene: 157961529

Following gene: 157961527

Centisome position: 40.01

GC content: 48.5

Gene sequence:

>1002_bases
ATGCTAAAAGGCACGTTTTTTTGCGTTGATGCTCATACCTGTGGCAACCCAGTCAGATTAGTTACCAGCGGCCATCCTCA
CCTTCTCGGCGATAACATGAGCGATAAACGCCAACATTTTCTTCGTGAGTATGATTGGATCCGTAAAGCCTTGATGTTTG
AACCTCGCGGCCACGACATGATGTCAGGTGCTTTTCTTTACCCTCCTTGTTCAGACAGCGCCGACGCCTCAATCCTTTTT
ATCGAAACCAGTGGCTGCTTACCTATGTGCGGTCATGGCACCATAGGCACTATCACGGCCGCTATTGAGTCGGGCTTACT
TACAGCAAAGACACCTGGGCAATTGATTATCGATGTTCCAGCAGGACAGATAAAAATCGACTACCAACAAACAGGTGAAA
AAGTTGATTGGGTGAAAATTTATAATGTTGCTGCTTACTTAGCTCATCAAGATCAAATCCTAGACATTCCAGGACTCGGC
ACGCTCAAGGTCGATGTGTCATACGGTGGTAACTATTACGTTATCGTCGATCCCCAAGCAAACTTTCCGGGCCTTCGTCA
CTGGAGTGCAGGTGATATTTTAAAGTGGAGTCCGATAGTTAGAGAAGTGGCGCAGCAACAATTGAGCTGCATACACCCAG
ATGACCCAACCGTGAACGGCGTTAGCCACGTGCTTTGGACTGGAGATACCATCAGCGATGGTTCCGACGGTGCTAATGCC
GTTTTCTACGGCGATAAAGCTATCGACCGTTCGCCTTGCGGAACAGGCACCAGCGCGCGTCTTGCACAGCTTTATACCAA
AGGTCTGTTGAGCGTTGGCGATGAATACACCCATGAAAGCATTATCGGCAGCCAATTTGTCGGCCGTATCGAAGCTGAAA
CGACAGTCGGCGATCACAAGGCGATAATGCCAAGTATCAAAGGCTGGGCACGGATCATCGGCAAGAATGCCATTACTGTA
GATGATAACGACCCATATGCATTCGGTTTCCAGGTAGTGTAA

Upstream 100 bases:

>100_bases
ACTAATTAAAGTTTGATGTTTATAAAGCCAGCCGTTTAATGCAAATTAAACGACTGGCTTTGATCACTTTATCAATAACG
ATAACAATGGAGTGTTTTAC

Downstream 100 bases:

>100_bases
CCCTATAGAATTTCTAATTGAGCTTTAACACTCAGGAGCAAACATGACAGATTTAACCCAAGTTGCAATTTCAGGCCAAC
ATTTTATCAATGGTGCATGG

Product: hydroxyproline-2-epimerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MLKGTFFCVDAHTCGNPVRLVTSGHPHLLGDNMSDKRQHFLREYDWIRKALMFEPRGHDMMSGAFLYPPCSDSADASILF
IETSGCLPMCGHGTIGTITAAIESGLLTAKTPGQLIIDVPAGQIKIDYQQTGEKVDWVKIYNVAAYLAHQDQILDIPGLG
TLKVDVSYGGNYYVIVDPQANFPGLRHWSAGDILKWSPIVREVAQQQLSCIHPDDPTVNGVSHVLWTGDTISDGSDGANA
VFYGDKAIDRSPCGTGTSARLAQLYTKGLLSVGDEYTHESIIGSQFVGRIEAETTVGDHKAIMPSIKGWARIIGKNAITV
DDNDPYAFGFQVV

Sequences:

>Translated_333_residues
MLKGTFFCVDAHTCGNPVRLVTSGHPHLLGDNMSDKRQHFLREYDWIRKALMFEPRGHDMMSGAFLYPPCSDSADASILF
IETSGCLPMCGHGTIGTITAAIESGLLTAKTPGQLIIDVPAGQIKIDYQQTGEKVDWVKIYNVAAYLAHQDQILDIPGLG
TLKVDVSYGGNYYVIVDPQANFPGLRHWSAGDILKWSPIVREVAQQQLSCIHPDDPTVNGVSHVLWTGDTISDGSDGANA
VFYGDKAIDRSPCGTGTSARLAQLYTKGLLSVGDEYTHESIIGSQFVGRIEAETTVGDHKAIMPSIKGWARIIGKNAITV
DDNDPYAFGFQVV
>Mature_333_residues
MLKGTFFCVDAHTCGNPVRLVTSGHPHLLGDNMSDKRQHFLREYDWIRKALMFEPRGHDMMSGAFLYPPCSDSADASILF
IETSGCLPMCGHGTIGTITAAIESGLLTAKTPGQLIIDVPAGQIKIDYQQTGEKVDWVKIYNVAAYLAHQDQILDIPGLG
TLKVDVSYGGNYYVIVDPQANFPGLRHWSAGDILKWSPIVREVAQQQLSCIHPDDPTVNGVSHVLWTGDTISDGSDGANA
VFYGDKAIDRSPCGTGTSARLAQLYTKGLLSVGDEYTHESIIGSQFVGRIEAETTVGDHKAIMPSIKGWARIIGKNAITV
DDNDPYAFGFQVV

Specific function: Unknown

COG id: COG3938

COG function: function code E; Proline racemase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the proline racemase family [H]

Homologues:

Organism=Homo sapiens, GI21389361, Length=336, Percent_Identity=32.7380952380952, Blast_Score=172, Evalue=6e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008794 [H]

Pfam domain/function: PF05544 Pro_racemase [H]

EC number: NA

Molecular weight: Translated: 36158; Mature: 36158

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKGTFFCVDAHTCGNPVRLVTSGHPHLLGDNMSDKRQHFLREYDWIRKALMFEPRGHDM
CCCEEEEEEECCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCC
MSGAFLYPPCSDSADASILFIETSGCLPMCGHGTIGTITAAIESGLLTAKTPGQLIIDVP
CCCCEECCCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHCCEEEECCCCCEEEECC
AGQIKIDYQQTGEKVDWVKIYNVAAYLAHQDQILDIPGLGTLKVDVSYGGNYYVIVDPQA
CCEEEEEHHHCCCEECEEEEEEHHHHHHCCCCEEECCCCCEEEEEEEECCEEEEEECCCC
NFPGLRHWSAGDILKWSPIVREVAQQQLSCIHPDDPTVNGVSHVLWTGDTISDGSDGANA
CCCCCCCCCCCCCEECCHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCCCCCCCCE
VFYGDKAIDRSPCGTGTSARLAQLYTKGLLSVGDEYTHESIIGSQFVGRIEAETTVGDHK
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEECCCCCCCH
AIMPSIKGWARIIGKNAITVDDNDPYAFGFQVV
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEC
>Mature Secondary Structure
MLKGTFFCVDAHTCGNPVRLVTSGHPHLLGDNMSDKRQHFLREYDWIRKALMFEPRGHDM
CCCEEEEEEECCCCCCCEEEEECCCCEEECCCCCHHHHHHHHHHHHHHHHHEECCCCCCC
MSGAFLYPPCSDSADASILFIETSGCLPMCGHGTIGTITAAIESGLLTAKTPGQLIIDVP
CCCCEECCCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHCCEEEECCCCCEEEECC
AGQIKIDYQQTGEKVDWVKIYNVAAYLAHQDQILDIPGLGTLKVDVSYGGNYYVIVDPQA
CCEEEEEHHHCCCEECEEEEEEHHHHHHCCCCEEECCCCCEEEEEEEECCEEEEEECCCC
NFPGLRHWSAGDILKWSPIVREVAQQQLSCIHPDDPTVNGVSHVLWTGDTISDGSDGANA
CCCCCCCCCCCCCEECCHHHHHHHHHHHHEECCCCCCCCCCEEEEECCCCCCCCCCCCCE
VFYGDKAIDRSPCGTGTSARLAQLYTKGLLSVGDEYTHESIIGSQFVGRIEAETTVGDHK
EEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCEEEECCCCCCCH
AIMPSIKGWARIIGKNAITVDDNDPYAFGFQVV
HHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]