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The map label for this gene is aldH [H]

Identifier: 157961527

GI number: 157961527

Start: 2067982

End: 2069547

Strand: Reverse

Name: aldH [H]

Synonym: Spea_1702

Alternate gene names: 157961527

Gene position: 2069547-2067982 (Counterclockwise)

Preceding gene: 157961528

Following gene: 157961526

Centisome position: 39.99

GC content: 48.34

Gene sequence:

>1566_bases
ATGACAGATTTAACCCAAGTTGCAATTTCAGGCCAACATTTTATCAATGGTGCATGGACTAACGAATCAACCGACTTTAA
CAGTACTAATCCTGTGACCAACGAAGCACTCACATGGCGCTTTGCAAACGCAAGCCAGGCTGTGGTTGAAAGTGCAACGG
CTGCGGCTAAGAAAGCTTTTGTTCAATACCGTAGCCTAGCGCCGACTCGTCGCGCAGAATTTCTTGAAGCGATTGCCGAT
GAAATTCAAGCTGACATAGCAGCAATTACCGAGACGGCTCACTTGGAAACCGGTCTACCAATGGCGCGTCTTCAAGGCGA
GACAGGGCGTACTTGTGGTCAACTAAGATTATTCGCTGGCAACCTTAGAAACCCAATTGATAACCGCTATGTGGATCTGG
CTAACCCAGAAAGACAGCCACTACCAAAGCCAGATACAAGACTGACAACCCTTCCACTAGGCCCTGTTGCTGTTTTTGGT
GCATCTAACTTCCCACTTGCATTTTCAACTGCGGGTGGCGACACAGCATCGGCCCTCGCTGCTGGCTGTACGATTGTAGT
TAAAGGCCATCCTGCACACGCCGCAACCAGTGAATTAGTCAGCCGCGCAATCGAGCGTGCTGCAGTTAAGTGCGATATGC
CAAACGGCGTATTTAATCTGGTACAAGGTTTTGCACCTGAGGTGTCAACTACACTGGTCAAAGATCCTGCCATCAAGGCT
GTAGGCTTTACTGGTTCACTCAAGGTAGGCCGCATCTTATCTGATCTATGTGCCGCACGTGCTGAACCTATCCCATTTTA
TGGCGAGTTAGGTTCAATCAACCCGCAATTTATCTTAGCTGAGATCTTAGAAGAGCAAGCTGAAAGCTTAGCATCGACTC
AAGTTCAATCTATGTTGATGGGACACGGGCAGTTCTGTACTAGCCCTGGAGTGATAGTCGCTGTAAAAGGTGAAGCACTT
AACCGCTACAAGGCAACTCTGGCACAAGATATCGCATCTCAAAGCGCGGCTAGCATGCTGACAGCTGGAATCGCCAGCAC
ATATCAAGCGCAAATTGAAGCGCTAGTAGCCAATCCAAAAGTAGAGCTTATCGCTCAAGGTGAGTCTTCGCCAGCTAACC
ACTTTACCCGCCCAACTGCATTAAAAGTGACAGCTGCAGATTTTATCGCATCAAATGACATTCAGCAGGAAGTGTTCGGT
CCATGTGCAGTGCTAGTTGAGTGTGATGATCGCGCACAGATGCAGTCTATTGCCGAACAACTTGAAGGGCAGCTTACCGC
GTCAGTACACGGTTTAGAGTCTGAAATCACAGAAAATAGAACCCTAATTGAAGCTATAGCCTTCAATGTTGGCCGTTTAA
TTTTCAACCAGATGCCTACAGGCGTTGAGGTGTGCCACACAATGAACCACGGTGGCCCATACCCAGCCAGTACCGATAGC
CGTACAACCTCAGTCGGTTCAGCTGCAATGGCACGATTCGAGCGAGCTATTTGTTATCAGAATATGCCAAAAGCGCTATT
ACCGACTCGCGTTATTGAAGGCCAAACTGGCGTCATCACGTTTTAA

Upstream 100 bases:

>100_bases
AATGCCATTACTGTAGATGATAACGACCCATATGCATTCGGTTTCCAGGTAGTGTAACCCTATAGAATTTCTAATTGAGC
TTTAACACTCAGGAGCAAAC

Downstream 100 bases:

>100_bases
GTATGTCAAATGTGAAAGGGAAACCTATGGTTTCCCTTTCATTATAATGGCATTAGCGGTAACCTAGGACGGATCAACTT
GTATAAATAACAAAAAAATC

Product: aldehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 520

Protein sequence:

>521_residues
MTDLTQVAISGQHFINGAWTNESTDFNSTNPVTNEALTWRFANASQAVVESATAAAKKAFVQYRSLAPTRRAEFLEAIAD
EIQADIAAITETAHLETGLPMARLQGETGRTCGQLRLFAGNLRNPIDNRYVDLANPERQPLPKPDTRLTTLPLGPVAVFG
ASNFPLAFSTAGGDTASALAAGCTIVVKGHPAHAATSELVSRAIERAAVKCDMPNGVFNLVQGFAPEVSTTLVKDPAIKA
VGFTGSLKVGRILSDLCAARAEPIPFYGELGSINPQFILAEILEEQAESLASTQVQSMLMGHGQFCTSPGVIVAVKGEAL
NRYKATLAQDIASQSAASMLTAGIASTYQAQIEALVANPKVELIAQGESSPANHFTRPTALKVTAADFIASNDIQQEVFG
PCAVLVECDDRAQMQSIAEQLEGQLTASVHGLESEITENRTLIEAIAFNVGRLIFNQMPTGVEVCHTMNHGGPYPASTDS
RTTSVGSAAMARFERAICYQNMPKALLPTRVIEGQTGVITF

Sequences:

>Translated_521_residues
MTDLTQVAISGQHFINGAWTNESTDFNSTNPVTNEALTWRFANASQAVVESATAAAKKAFVQYRSLAPTRRAEFLEAIAD
EIQADIAAITETAHLETGLPMARLQGETGRTCGQLRLFAGNLRNPIDNRYVDLANPERQPLPKPDTRLTTLPLGPVAVFG
ASNFPLAFSTAGGDTASALAAGCTIVVKGHPAHAATSELVSRAIERAAVKCDMPNGVFNLVQGFAPEVSTTLVKDPAIKA
VGFTGSLKVGRILSDLCAARAEPIPFYGELGSINPQFILAEILEEQAESLASTQVQSMLMGHGQFCTSPGVIVAVKGEAL
NRYKATLAQDIASQSAASMLTAGIASTYQAQIEALVANPKVELIAQGESSPANHFTRPTALKVTAADFIASNDIQQEVFG
PCAVLVECDDRAQMQSIAEQLEGQLTASVHGLESEITENRTLIEAIAFNVGRLIFNQMPTGVEVCHTMNHGGPYPASTDS
RTTSVGSAAMARFERAICYQNMPKALLPTRVIEGQTGVITF
>Mature_520_residues
TDLTQVAISGQHFINGAWTNESTDFNSTNPVTNEALTWRFANASQAVVESATAAAKKAFVQYRSLAPTRRAEFLEAIADE
IQADIAAITETAHLETGLPMARLQGETGRTCGQLRLFAGNLRNPIDNRYVDLANPERQPLPKPDTRLTTLPLGPVAVFGA
SNFPLAFSTAGGDTASALAAGCTIVVKGHPAHAATSELVSRAIERAAVKCDMPNGVFNLVQGFAPEVSTTLVKDPAIKAV
GFTGSLKVGRILSDLCAARAEPIPFYGELGSINPQFILAEILEEQAESLASTQVQSMLMGHGQFCTSPGVIVAVKGEALN
RYKATLAQDIASQSAASMLTAGIASTYQAQIEALVANPKVELIAQGESSPANHFTRPTALKVTAADFIASNDIQQEVFGP
CAVLVECDDRAQMQSIAEQLEGQLTASVHGLESEITENRTLIEAIAFNVGRLIFNQMPTGVEVCHTMNHGGPYPASTDSR
TTSVGSAAMARFERAICYQNMPKALLPTRVIEGQTGVITF

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI12007648, Length=440, Percent_Identity=24.0909090909091, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI25952152, Length=296, Percent_Identity=26.0135135135135, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI153266822, Length=308, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=8e-16,
Organism=Homo sapiens, GI4507229, Length=474, Percent_Identity=22.9957805907173, Blast_Score=82, Evalue=9e-16,
Organism=Homo sapiens, GI25777724, Length=423, Percent_Identity=24.3498817966903, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI25777721, Length=483, Percent_Identity=22.5672877846791, Blast_Score=76, Evalue=8e-14,
Organism=Escherichia coli, GI1789015, Length=436, Percent_Identity=26.8348623853211, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87081896, Length=410, Percent_Identity=27.3170731707317, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1788042, Length=295, Percent_Identity=30.1694915254237, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787250, Length=451, Percent_Identity=24.1685144124169, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1787715, Length=414, Percent_Identity=27.536231884058, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87082295, Length=309, Percent_Identity=24.9190938511327, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI25143876, Length=308, Percent_Identity=25.3246753246753, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI25143874, Length=308, Percent_Identity=25.3246753246753, Blast_Score=86, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI133930964, Length=464, Percent_Identity=25.2155172413793, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115534176, Length=320, Percent_Identity=26.5625, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71986308, Length=425, Percent_Identity=24.4705882352941, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17534119, Length=443, Percent_Identity=25.7336343115124, Blast_Score=68, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6319478, Length=432, Percent_Identity=24.537037037037, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6324950, Length=495, Percent_Identity=25.4545454545455, Blast_Score=97, Evalue=8e-21,
Organism=Saccharomyces cerevisiae, GI6325196, Length=409, Percent_Identity=24.2053789731051, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320917, Length=431, Percent_Identity=22.969837587007, Blast_Score=73, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281362580, Length=306, Percent_Identity=29.0849673202614, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI62472918, Length=306, Percent_Identity=29.0849673202614, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI62472926, Length=306, Percent_Identity=29.0849673202614, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI62472936, Length=306, Percent_Identity=29.0849673202614, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356737, Length=306, Percent_Identity=29.0849673202614, Blast_Score=91, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24650465, Length=298, Percent_Identity=25.503355704698, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24666674, Length=346, Percent_Identity=25.7225433526012, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 55292; Mature: 55161

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLTQVAISGQHFINGAWTNESTDFNSTNPVTNEALTWRFANASQAVVESATAAAKKAF
CCCHHHHEECCCCEECCEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
VQYRSLAPTRRAEFLEAIADEIQADIAAITETAHLETGLPMARLQGETGRTCGQLRLFAG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHEEEECC
NLRNPIDNRYVDLANPERQPLPKPDTRLTTLPLGPVAVFGASNFPLAFSTAGGDTASALA
CCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEEEECCCCCHHHHHH
AGCTIVVKGHPAHAATSELVSRAIERAAVKCDMPNGVFNLVQGFAPEVSTTLVKDPAIKA
CCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHCCCCEEE
VGFTGSLKVGRILSDLCAARAEPIPFYGELGSINPQFILAEILEEQAESLASTQVQSMLM
ECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GHGQFCTSPGVIVAVKGEALNRYKATLAQDIASQSAASMLTAGIASTYQAQIEALVANPK
CCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VELIAQGESSPANHFTRPTALKVTAADFIASNDIQQEVFGPCAVLVECDDRAQMQSIAEQ
EEEEECCCCCCCCCCCCCCEEEEEHHHHHHCCCHHHHHCCCEEEEEECCCHHHHHHHHHH
LEGQLTASVHGLESEITENRTLIEAIAFNVGRLIFNQMPTGVEVCHTMNHGGPYPASTDS
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
RTTSVGSAAMARFERAICYQNMPKALLPTRVIEGQTGVITF
CCHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCCCCCEEEC
>Mature Secondary Structure 
TDLTQVAISGQHFINGAWTNESTDFNSTNPVTNEALTWRFANASQAVVESATAAAKKAF
CCHHHHEECCCCEECCEECCCCCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHH
VQYRSLAPTRRAEFLEAIADEIQADIAAITETAHLETGLPMARLQGETGRTCGQLRLFAG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHHEEEECC
NLRNPIDNRYVDLANPERQPLPKPDTRLTTLPLGPVAVFGASNFPLAFSTAGGDTASALA
CCCCCCCCCEEECCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCEEEECCCCCHHHHHH
AGCTIVVKGHPAHAATSELVSRAIERAAVKCDMPNGVFNLVQGFAPEVSTTLVKDPAIKA
CCCEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHCCCCEEE
VGFTGSLKVGRILSDLCAARAEPIPFYGELGSINPQFILAEILEEQAESLASTQVQSMLM
ECCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
GHGQFCTSPGVIVAVKGEALNRYKATLAQDIASQSAASMLTAGIASTYQAQIEALVANPK
CCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
VELIAQGESSPANHFTRPTALKVTAADFIASNDIQQEVFGPCAVLVECDDRAQMQSIAEQ
EEEEECCCCCCCCCCCCCCEEEEEHHHHHHCCCHHHHHCCCEEEEEECCCHHHHHHHHHH
LEGQLTASVHGLESEITENRTLIEAIAFNVGRLIFNQMPTGVEVCHTMNHGGPYPASTDS
HCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCC
RTTSVGSAAMARFERAICYQNMPKALLPTRVIEGQTGVITF
CCHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]