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The map label for this gene is atoS [H]

Identifier: 157961186

GI number: 157961186

Start: 1654839

End: 1655954

Strand: Direct

Name: atoS [H]

Synonym: Spea_1358

Alternate gene names: 157961186

Gene position: 1654839-1655954 (Clockwise)

Preceding gene: 157961185

Following gene: 157961187

Centisome position: 31.98

GC content: 46.42

Gene sequence:

>1116_bases
ATGTCAGCAATTCCACAATCACAAGTCGATGCCAGCGATTCAACTAACGCAATAGCGGCGAAGCGTCCGCACTTGGTTGA
CGTTCAGCAAGCCGCAAATATGTCCAATCGTATGGATCATATTCTGCAGGCTATGCCATCTGGCGTGGTGATTATCAGCG
GTGATGGCATTGTTACCGAGGCTAACCCTGTGGCTGTTGAACTCTTAGGTAGCCCATTAGAAGGGCTGCGCTGGCTACAA
ATCATCAATCGAGCGTTTTCTCCACAAGATGATGATGGTCACGAGGTCTCATTGCGTAACGGTCGCCGGGTAAAACTCGC
TATTACGCCGCTTACGCCAGAGCCTGGTCAACTTATCGTGCTGACGGATTTGACCGAAACTCGTTTACTGCAAAAGAACT
TATCGCATCTGCAAAGATTATCGGCGCTAGGGAAGATGGTGGCGACACTTGCCCATCAAGTGAGAACCCCTCTAAGTGCG
GCTCTTTTATATGCCTCAAACTTGGCTAGCCCTAAAATATCAGAAGATTCGCGTAAGCGCTTTCAAGGCAAGTTAGTCGA
CAGACTCAATGAATTAGAGCATCAAGTGAACGATATGCTGCTGATGGCAAAGGGTCGTCAACAGGAGCTAGACTCAATCC
TGGTTATCGATGAAGTGGTTGATAATGTACTGAGTAACTGTCAGCCGATAGCGGAGCAAAAAGGCTGTCAGTTGATATTT
AACAATCAATCAAAACAAAAAATTCGTGCTAATGACGCGGCGCTTTGCTCGGCAATCAATAACCTTGTGATGAACAGTTT
AGAAGCTGAGGCTAGCCAAATCACCTTGCATGCATATGACACTCAAACCGCATTACACCTAGACGTGATCGATAATGGTA
AGGGGCTCGATGCCAACATGCAGCAAAAGGTACTAGAGCCATTTTTTACTACTAAGTCTCAAGGTACGGGTTTGGGTTTA
GCCGTGGTTCAAGCGGTGGTCAATAACCATGGGGGAATGATGCAGTTTAGCTGTCATCCCGGTAATGGCTGCACTGCGTC
ATTAAAGTTTCCGTTGATCACGACCATTAATAACCATAATAACAATGAAGTGCTTGGAGATAATCAGCATGTCTGA

Upstream 100 bases:

>100_bases
GCGTAGTCACGTCCTCGCAGCGCAGCGTCCTTCTTTTAAAGATAACTGGCATAATTCCTGCTTGAACTCATTCAAATGCA
GTTTTTTTGACGGGGTTACC

Downstream 100 bases:

>100_bases
AGGTAAGTTATTACTTGTAGAAGATGATGCTTCACTGCGTGAAGCACTGCTCGATACCTTGATGTTAGCGCATTATGATT
GTGTCGATGTCGCTTCGGCA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MSAIPQSQVDASDSTNAIAAKRPHLVDVQQAANMSNRMDHILQAMPSGVVIISGDGIVTEANPVAVELLGSPLEGLRWLQ
IINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSA
ALLYASNLASPKISEDSRKRFQGKLVDRLNELEHQVNDMLLMAKGRQQELDSILVIDEVVDNVLSNCQPIAEQKGCQLIF
NNQSKQKIRANDAALCSAINNLVMNSLEAEASQITLHAYDTQTALHLDVIDNGKGLDANMQQKVLEPFFTTKSQGTGLGL
AVVQAVVNNHGGMMQFSCHPGNGCTASLKFPLITTINNHNNNEVLGDNQHV

Sequences:

>Translated_371_residues
MSAIPQSQVDASDSTNAIAAKRPHLVDVQQAANMSNRMDHILQAMPSGVVIISGDGIVTEANPVAVELLGSPLEGLRWLQ
IINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSA
ALLYASNLASPKISEDSRKRFQGKLVDRLNELEHQVNDMLLMAKGRQQELDSILVIDEVVDNVLSNCQPIAEQKGCQLIF
NNQSKQKIRANDAALCSAINNLVMNSLEAEASQITLHAYDTQTALHLDVIDNGKGLDANMQQKVLEPFFTTKSQGTGLGL
AVVQAVVNNHGGMMQFSCHPGNGCTASLKFPLITTINNHNNNEVLGDNQHV
>Mature_370_residues
SAIPQSQVDASDSTNAIAAKRPHLVDVQQAANMSNRMDHILQAMPSGVVIISGDGIVTEANPVAVELLGSPLEGLRWLQI
INRAFSPQDDDGHEVSLRNGRRVKLAITPLTPEPGQLIVLTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAA
LLYASNLASPKISEDSRKRFQGKLVDRLNELEHQVNDMLLMAKGRQQELDSILVIDEVVDNVLSNCQPIAEQKGCQLIFN
NQSKQKIRANDAALCSAINNLVMNSLEAEASQITLHAYDTQTALHLDVIDNGKGLDANMQQKVLEPFFTTKSQGTGLGLA
VVQAVVNNHGGMMQFSCHPGNGCTASLKFPLITTINNHNNNEVLGDNQHV

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=356, Percent_Identity=27.8089887640449, Blast_Score=115, Evalue=7e-27,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=31.063829787234, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790346, Length=221, Percent_Identity=25.7918552036199, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786600, Length=350, Percent_Identity=23.1428571428571, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1790300, Length=241, Percent_Identity=26.1410788381743, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788713, Length=253, Percent_Identity=25.296442687747, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788279, Length=206, Percent_Identity=25.7281553398058, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 40310; Mature: 40178

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAIPQSQVDASDSTNAIAAKRPHLVDVQQAANMSNRMDHILQAMPSGVVIISGDGIVTE
CCCCCCCCCCCCCCCCCEECCCCCEEEHHHHHCHHHHHHHHHHHCCCCEEEECCCCEEEC
ANPVAVELLGSPLEGLRWLQIINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPEPGQLIV
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEE
LTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAALLYASNLASPKISEDSRKR
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHH
FQGKLVDRLNELEHQVNDMLLMAKGRQQELDSILVIDEVVDNVLSNCQPIAEQKGCQLIF
HHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEE
NNQSKQKIRANDAALCSAINNLVMNSLEAEASQITLHAYDTQTALHLDVIDNGKGLDANM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEEECCCCCCCHH
QQKVLEPFFTTKSQGTGLGLAVVQAVVNNHGGMMQFSCHPGNGCTASLKFPLITTINNHN
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECEEEEEECCCC
NNEVLGDNQHV
CCCCCCCCCCC
>Mature Secondary Structure 
SAIPQSQVDASDSTNAIAAKRPHLVDVQQAANMSNRMDHILQAMPSGVVIISGDGIVTE
CCCCCCCCCCCCCCCCEECCCCCEEEHHHHHCHHHHHHHHHHHCCCCEEEECCCCEEEC
ANPVAVELLGSPLEGLRWLQIINRAFSPQDDDGHEVSLRNGRRVKLAITPLTPEPGQLIV
CCCEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEEEECCCCCCCCEEE
LTDLTETRLLQKNLSHLQRLSALGKMVATLAHQVRTPLSAALLYASNLASPKISEDSRKR
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCCCHHHHHH
FQGKLVDRLNELEHQVNDMLLMAKGRQQELDSILVIDEVVDNVLSNCQPIAEQKGCQLIF
HHHHHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCEEEE
NNQSKQKIRANDAALCSAINNLVMNSLEAEASQITLHAYDTQTALHLDVIDNGKGLDANM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEEECCCCCCCHH
QQKVLEPFFTTKSQGTGLGLAVVQAVVNNHGGMMQFSCHPGNGCTASLKFPLITTINNHN
HHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCEEEEECEEEEEECCCC
NNEVLGDNQHV
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]