Click here to switch to the map view.

The map label for this gene is rbsK [H]

Identifier: 157960839

GI number: 157960839

Start: 1229331

End: 1230527

Strand: Reverse

Name: rbsK [H]

Synonym: Spea_1011

Alternate gene names: 157960839

Gene position: 1230527-1229331 (Counterclockwise)

Preceding gene: 157960840

Following gene: 157960837

Centisome position: 23.78

GC content: 42.19

Gene sequence:

>1197_bases
ATGAACTTATTAAGCCGAAATGAAAGGCTGACAGTTATCTTAAGGCTGCTCAGTAAACATAAAACCTTATCCAATACACA
ATTAGCTAAGTTACTTCAAGTAACTCCAAAGACTATCCGTTGCGACTTAGTATATCTGGAACAAGAAAAGCAAGTGATAA
GGATACACGGAGGCGTAAAACGCTCTGAAGACTTGGATGTCAATGCCTACAGCTTAGATAGCTTACTTTCTCGGTTAACC
TCCTGTAGAGCAGAGCTTGATCTCGTAAATCAAGGCGGTAATATCTTGAAGAACAAAATTTTTGTACTTGGCTCCTTTAA
CGTGGACATAGTCGCAAAACTAGAGCGTTTTCCGCAAGTAGGTGAGACTCTTCACTCTCAGAACTACAAAATAGGCGCAG
GAGGTAAAGGCGCAAATCAAGCCTATGCTGCAGCAAAAGTTGGCGCAAGAGTGACTTTTATGACTAAGATAGGCAAAGAT
CAATTTAGCCATTTTGCTAAAGCCCACCTAGCAAGTACTGAAATAGACAGCACTATTATAGTCGAGTCTGATACAAGCCC
AACCGGAAATGCGCTCATCTATGTTTGTGAGCAATCAGGTGAAAATATGATTGCCGTTTATTCCGGCGCTAATATTGAGA
TCACTCAAGAAGAGATTCAACAAGCAGAGCAACATATCATTAGTTCTAGCTTGTTTTTGACTCAACTTGAAAATAATATC
GAGGCGATCAAACAAGCAATGATGACTGCCCATAAACATAAAGTGAAAGTGGTACTCAATCCAGCACCTTACCATGAGAA
TACACCTGACTTATTAGAGTTTGTAGATCTCATCACCCCTAATGAAACCGAAGCCTCGTTAATGACCGGAATCGAAGTAA
CAGACCTCGACAGTGCTAAACGAGCAGCTGAAAAAATCAAGCTAATGGGGGTCAATACTGTGGTTATCACTCGCGGCGCT
AAAGGTGCCCTACTTTATGAAAATGGAAACTTCAAAGAGGTTGAAGCGATTAAATGTGCTGTCACCGACACAACTGGTGC
AGGAGATGCATTTAATGGCGCTCTAGTGGCTCAAATAGCTAAAGGTGAAACATTGCTAGATGCCGCAAGGTATGCCAATG
CATATGCCTCTCTCGCCGTAGAGCGTGAAGGCGCAGCAAATATGCCGGACGCAAATCTAATTGCGGCACGACTATAA

Upstream 100 bases:

>100_bases
ATAGACAATAGTCAAAAAACAAACCTAGCAGTTCGTTTAGCATGCAAAGCTTTCTCATCAATCACAGCCTAAGACATGCT
GAACGCGTATATTGCCCCAT

Downstream 100 bases:

>100_bases
ATCTGATGCGCAGTAGTAATTTCAATTGCTATTAAAGCACGCAACTCAGCAAAAGTATGGCGATACTTAAGCTCATTACT
AGCTCCATGTGCAATACCCG

Product: ribokinase-like domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MNLLSRNERLTVILRLLSKHKTLSNTQLAKLLQVTPKTIRCDLVYLEQEKQVIRIHGGVKRSEDLDVNAYSLDSLLSRLT
SCRAELDLVNQGGNILKNKIFVLGSFNVDIVAKLERFPQVGETLHSQNYKIGAGGKGANQAYAAAKVGARVTFMTKIGKD
QFSHFAKAHLASTEIDSTIIVESDTSPTGNALIYVCEQSGENMIAVYSGANIEITQEEIQQAEQHIISSSLFLTQLENNI
EAIKQAMMTAHKHKVKVVLNPAPYHENTPDLLEFVDLITPNETEASLMTGIEVTDLDSAKRAAEKIKLMGVNTVVITRGA
KGALLYENGNFKEVEAIKCAVTDTTGAGDAFNGALVAQIAKGETLLDAARYANAYASLAVEREGAANMPDANLIAARL

Sequences:

>Translated_398_residues
MNLLSRNERLTVILRLLSKHKTLSNTQLAKLLQVTPKTIRCDLVYLEQEKQVIRIHGGVKRSEDLDVNAYSLDSLLSRLT
SCRAELDLVNQGGNILKNKIFVLGSFNVDIVAKLERFPQVGETLHSQNYKIGAGGKGANQAYAAAKVGARVTFMTKIGKD
QFSHFAKAHLASTEIDSTIIVESDTSPTGNALIYVCEQSGENMIAVYSGANIEITQEEIQQAEQHIISSSLFLTQLENNI
EAIKQAMMTAHKHKVKVVLNPAPYHENTPDLLEFVDLITPNETEASLMTGIEVTDLDSAKRAAEKIKLMGVNTVVITRGA
KGALLYENGNFKEVEAIKCAVTDTTGAGDAFNGALVAQIAKGETLLDAARYANAYASLAVEREGAANMPDANLIAARL
>Mature_398_residues
MNLLSRNERLTVILRLLSKHKTLSNTQLAKLLQVTPKTIRCDLVYLEQEKQVIRIHGGVKRSEDLDVNAYSLDSLLSRLT
SCRAELDLVNQGGNILKNKIFVLGSFNVDIVAKLERFPQVGETLHSQNYKIGAGGKGANQAYAAAKVGARVTFMTKIGKD
QFSHFAKAHLASTEIDSTIIVESDTSPTGNALIYVCEQSGENMIAVYSGANIEITQEEIQQAEQHIISSSLFLTQLENNI
EAIKQAMMTAHKHKVKVVLNPAPYHENTPDLLEFVDLITPNETEASLMTGIEVTDLDSAKRAAEKIKLMGVNTVVITRGA
KGALLYENGNFKEVEAIKCAVTDTTGAGDAFNGALVAQIAKGETLLDAARYANAYASLAVEREGAANMPDANLIAARL

Specific function: Ribose metabolism; first step. [C]

COG id: COG0524

COG function: function code G; Sugar kinases, ribokinase family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Homo sapiens, GI11545855, Length=286, Percent_Identity=32.8671328671329, Blast_Score=144, Evalue=1e-34,
Organism=Escherichia coli, GI1790193, Length=286, Percent_Identity=39.8601398601399, Blast_Score=192, Evalue=2e-50,
Organism=Escherichia coli, GI87082343, Length=295, Percent_Identity=25.7627118644068, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081971, Length=263, Percent_Identity=26.9961977186312, Blast_Score=79, Evalue=5e-16,
Organism=Escherichia coli, GI1788491, Length=317, Percent_Identity=24.2902208201893, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788017, Length=259, Percent_Identity=26.6409266409266, Blast_Score=66, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17532905, Length=289, Percent_Identity=37.0242214532872, Blast_Score=171, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6319884, Length=329, Percent_Identity=30.6990881458967, Blast_Score=118, Evalue=1e-27,
Organism=Drosophila melanogaster, GI20128807, Length=306, Percent_Identity=33.6601307189542, Blast_Score=138, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24583886, Length=288, Percent_Identity=29.1666666666667, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR011877
- InterPro:   IPR002139 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.15 [H]

Molecular weight: Translated: 43241; Mature: 43241

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS51000 HTH_DEOR_2 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLLSRNERLTVILRLLSKHKTLSNTQLAKLLQVTPKTIRCDLVYLEQEKQVIRIHGGVK
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCC
RSEDLDVNAYSLDSLLSRLTSCRAELDLVNQGGNILKNKIFVLGSFNVDIVAKLERFPQV
CCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEECEEEEEECCCHHHHHHHHHCHHH
GETLHSQNYKIGAGGKGANQAYAAAKVGARVTFMTKIGKDQFSHFAKAHLASTEIDSTII
HHHHHCCCEEECCCCCCCCHHHHHHHHCCEEEEEEHHCHHHHHHHHHHHHCCCCCCCEEE
VESDTSPTGNALIYVCEQSGENMIAVYSGANIEITQEEIQQAEQHIISSSLFLTQLENNI
EECCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
EAIKQAMMTAHKHKVKVVLNPAPYHENTPDLLEFVDLITPNETEASLMTGIEVTDLDSAK
HHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCEEECCCHHH
RAAEKIKLMGVNTVVITRGAKGALLYENGNFKEVEAIKCAVTDTTGAGDAFNGALVAQIA
HHHHHEEEEECEEEEEECCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEC
KGETLLDAARYANAYASLAVEREGAANMPDANLIAARL
CCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEECC
>Mature Secondary Structure
MNLLSRNERLTVILRLLSKHKTLSNTQLAKLLQVTPKTIRCDLVYLEQEKQVIRIHGGVK
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEEEEEECCCEEEEEECCCC
RSEDLDVNAYSLDSLLSRLTSCRAELDLVNQGGNILKNKIFVLGSFNVDIVAKLERFPQV
CCCCCCCCCCCHHHHHHHHHHHHHHHHEECCCCCEEECEEEEEECCCHHHHHHHHHCHHH
GETLHSQNYKIGAGGKGANQAYAAAKVGARVTFMTKIGKDQFSHFAKAHLASTEIDSTII
HHHHHCCCEEECCCCCCCCHHHHHHHHCCEEEEEEHHCHHHHHHHHHHHHCCCCCCCEEE
VESDTSPTGNALIYVCEQSGENMIAVYSGANIEITQEEIQQAEQHIISSSLFLTQLENNI
EECCCCCCCCEEEEEEECCCCCEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHH
EAIKQAMMTAHKHKVKVVLNPAPYHENTPDLLEFVDLITPNETEASLMTGIEVTDLDSAK
HHHHHHHHHHHCCEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHCCCEEECCCHHH
RAAEKIKLMGVNTVVITRGAKGALLYENGNFKEVEAIKCAVTDTTGAGDAFNGALVAQIA
HHHHHEEEEECEEEEEECCCCCEEEEECCCCCEEEEEEEEEECCCCCCCCCCCCEEEEEC
KGETLLDAARYANAYASLAVEREGAANMPDANLIAARL
CCCHHHHHHHHHHHHHHEEEECCCCCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]