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The map label for this gene is fba [H]

Identifier: 157960619

GI number: 157960619

Start: 979126

End: 980190

Strand: Direct

Name: fba [H]

Synonym: Spea_0791

Alternate gene names: 157960619

Gene position: 979126-980190 (Clockwise)

Preceding gene: 157960618

Following gene: 157960620

Centisome position: 18.92

GC content: 48.45

Gene sequence:

>1065_bases
ATGGCCTTAATTTCCCTACGTCAAATGTTAGATCACGCTGCAGAGCACGGATATGGCGTTCCAGCGTTTAACGTGAATAA
CCTTGAGCAGATGCGTGCAATTATGCAGGCAGCTGAAGCAACAGACAGCCCAGTAATCGTTCAGGCTTCTGCTGGTGCAC
GTAAGTACGCACGTCCACAGTTTCTAAAGTATCTAATGGCTGCTGCACTTGAGCAGTATCCAGATATCCCAGTATGTATT
CACCAGGACCACGGTACTGATCCTGATATCTGTCAGCGTTCTATCCAGTTGGGTATGTCATCTGTAATGATGGACGGCTC
TTTGATGGCTGATGGTAAGACACCAGCATCATATGAGTACAACGTAGACGTGACTCGCCGTACAGTTGCTTTTGCTCACG
CTTGTGGTGTGTCTGTTGAAGGTGAAATCGGCTGTCTAGGTAGCCTAGAAACCGGTATGGCTGGTGAAGAAGACGGTGTT
GGCGCAGAAGGTATTCTAAGTCACGACCAACTGCTAACGACGCCTGAAGAAGCGGCGCGTTTCGTTGCTGATACGCACGT
CGATGCTCTAGCAATTGCTATTGGTACTAGCCACGGTGCTTACAAGTTTAGCCGTAAGCCTACCGGTGACGTTCTGCGTA
TCGACCGTATCAAAGAGATCCACGCACGTATTCCTAACACTCACCTTGTTATGCACGGTTCATCTTCAGTGCCGCAAGAG
TGGTTAGAGATCATCAACCAGTATGGTGGTGCCATCCCTGAAACTTACGGTGTACCACTAGAAGAGATCGTTGAAGGCAT
TAAGCACGGCGTGCGTAAGGTCAACATCGATACCGATCTACGTCTAGCATCAACTGGTGCGGTACGTAAGTTCCTTGCTG
AAAACCCAGCGGAATTTGACCCACGTAAATTCTTGAAGGCGTCAATGGAAGCGATGGCTGACATCTGTACTACGCGTTAC
GAAGCTTTCGGTTGTGCGGGTATGGCGTCTAAGATCAAGCCTAAGTCACTACAAGCTATGTATAAAGCTTACCAGTCAGG
CGAACTTGATCCACAAATCAAGTAA

Upstream 100 bases:

>100_bases
TAGTGTTCATCAGTTTAATACTGGTAACGTTAGAGTATAAAAATCCATCCAAACGATAGTGACCTTGGTGAGGCGACTCA
CCCTATTATTGGAGTAAAAA

Downstream 100 bases:

>100_bases
GTTTAACTGTTAGTACTACTTCGACTAAAGCACCTATGCTTTAGCATAAAAATACCTGCCAATGTGCAGGTATTTTTTTG
CCTGCTGTTTATTGGCTGTG

Product: fructose-1,6-bisphosphate aldolase

Products: NA

Alternate protein names: FBP aldolase; FBPA; Fructose-1,6-bisphosphate aldolase [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MALISLRQMLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMAAALEQYPDIPVCI
HQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEYNVDVTRRTVAFAHACGVSVEGEIGCLGSLETGMAGEEDGV
GAEGILSHDQLLTTPEEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
WLEIINQYGGAIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAENPAEFDPRKFLKASMEAMADICTTRY
EAFGCAGMASKIKPKSLQAMYKAYQSGELDPQIK

Sequences:

>Translated_354_residues
MALISLRQMLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMAAALEQYPDIPVCI
HQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEYNVDVTRRTVAFAHACGVSVEGEIGCLGSLETGMAGEEDGV
GAEGILSHDQLLTTPEEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
WLEIINQYGGAIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAENPAEFDPRKFLKASMEAMADICTTRY
EAFGCAGMASKIKPKSLQAMYKAYQSGELDPQIK
>Mature_353_residues
ALISLRQMLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQFLKYLMAAALEQYPDIPVCIH
QDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEYNVDVTRRTVAFAHACGVSVEGEIGCLGSLETGMAGEEDGVG
AEGILSHDQLLTTPEEAARFVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQEW
LEIINQYGGAIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAENPAEFDPRKFLKASMEAMADICTTRYE
AFGCAGMASKIKPKSLQAMYKAYQSGELDPQIK

Specific function: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3- phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis [H]

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=330, Percent_Identity=34.2424242424242, Blast_Score=177, Evalue=1e-45,
Organism=Escherichia coli, GI87082041, Length=329, Percent_Identity=33.1306990881459, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1788072, Length=291, Percent_Identity=28.5223367697594, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1789293, Length=363, Percent_Identity=23.1404958677686, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006412
- InterPro:   IPR000771 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 38425; Mature: 38294

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00602 ALDOLASE_CLASS_II_1 ; PS00806 ALDOLASE_CLASS_II_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALISLRQMLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQ
CHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCHH
FLKYLMAAALEQYPDIPVCIHQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE
NVDVTRRTVAFAHACGVSVEGEIGCLGSLETGMAGEEDGVGAEGILSHDQLLTTPEEAAR
ECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHH
FVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
HHHHHCHHEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
WLEIINQYGGAIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAENPAEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHCCCCCCC
PRKFLKASMEAMADICTTRYEAFGCAGMASKIKPKSLQAMYKAYQSGELDPQIK
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ALISLRQMLDHAAEHGYGVPAFNVNNLEQMRAIMQAAEATDSPVIVQASAGARKYARPQ
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCHH
FLKYLMAAALEQYPDIPVCIHQDHGTDPDICQRSIQLGMSSVMMDGSLMADGKTPASYEY
HHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCCCCEEE
NVDVTRRTVAFAHACGVSVEGEIGCLGSLETGMAGEEDGVGAEGILSHDQLLTTPEEAAR
ECCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCHHHHHH
FVADTHVDALAIAIGTSHGAYKFSRKPTGDVLRIDRIKEIHARIPNTHLVMHGSSSVPQE
HHHHHCHHEEEEEEECCCCCEEECCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHH
WLEIINQYGGAIPETYGVPLEEIVEGIKHGVRKVNIDTDLRLASTGAVRKFLAENPAEFD
HHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCEEECCCCCCEEHHHHHHHHHHHCCCCCCC
PRKFLKASMEAMADICTTRYEAFGCAGMASKIKPKSLQAMYKAYQSGELDPQIK
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]