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The map label for this gene is speE [H]

Identifier: 157960573

GI number: 157960573

Start: 921814

End: 922557

Strand: Direct

Name: speE [H]

Synonym: Spea_0745

Alternate gene names: 157960573

Gene position: 921814-922557 (Clockwise)

Preceding gene: 157960571

Following gene: 157960574

Centisome position: 17.81

GC content: 49.19

Gene sequence:

>744_bases
ATGTCAGATTTTCAAACTTTACACCAAACCCAAGATGAATATGGTCCACTTATCGTACTCGAAGATAAGGAAACAAGGAT
CCTCGCCTTCGGCGAAAACGATGAGCAGAGTAAGTTACTCAAGGCTACGCCACATATTCCACAGCACACCTATGTGCAAG
CCATGCTATTGGTGCTGCTGTATAGCCAACCTAAGAGCGCTATCGTACTTGGTCTTGGTGGCGGTGGACTTATTCATGCG
CTGCGTCATTTCGATGCTGGGATAAAACTGACCGCAGTTGAGTTGCGAGCCGATGTGATTGAGCTGGCTAAGCGTTACTT
CCAGCTGCCGCTAAGCAAAAAGCTTAAAGTGATCAATCAAGATGCGAAGCTGTTTCTTGAATCTGGCGATCATAAGCGAG
TCGATGTGATCTTTGCCGATATCTATAGCGCCGATGGTGTCGATGCGGCTCAAGTGTCGGAGTCCTTTATTGCTCAATGC
GCCGCCTTGATTAAGGCCGACGGTTATTTGGTGTTGAACTGCTGGAAAGAGCACAGCCAGAACCGTGAGCTGCTTGCTTA
CCTCAACAGGTATTTCGTCGAGGTTCGCGCCTGCCTAACGGGCAGTGGTAACTGGGTGGTGTTTGCGGGTAAGGCCAAGC
GTGAGATCAGTGCCAGTGGCTTAAAAACCAAAGCACAGGCTTTGTCGCAGCAGTTGGATTTTCAACTCGGCAGATCGCTA
ACGCGATTCGACGTTTGGCAATAA

Upstream 100 bases:

>100_bases
CTGCGGGAGCGGTTTGAGTGCATATTAACAGCAGCATTTTATTGAAGCGGGTTTTTTCAAGTCGTTTGGGTATAATAGCG
CCCCAATTGTCGGAGCGCTC

Downstream 100 bases:

>100_bases
GCTTAACGCTATAATGTGAAGTCTAGCTCTGAGCTTACTAATCTCTGGAGGTTAAGCCACAGTAGCTCAAGTCTCTGTAG
GCTTAGTGTCAGTAAGTTAA

Product: spermine synthase

Products: NA

Alternate protein names: Putrescine aminopropyltransferase; PAPT; SPDSY [H]

Number of amino acids: Translated: 247; Mature: 246

Protein sequence:

>247_residues
MSDFQTLHQTQDEYGPLIVLEDKETRILAFGENDEQSKLLKATPHIPQHTYVQAMLLVLLYSQPKSAIVLGLGGGGLIHA
LRHFDAGIKLTAVELRADVIELAKRYFQLPLSKKLKVINQDAKLFLESGDHKRVDVIFADIYSADGVDAAQVSESFIAQC
AALIKADGYLVLNCWKEHSQNRELLAYLNRYFVEVRACLTGSGNWVVFAGKAKREISASGLKTKAQALSQQLDFQLGRSL
TRFDVWQ

Sequences:

>Translated_247_residues
MSDFQTLHQTQDEYGPLIVLEDKETRILAFGENDEQSKLLKATPHIPQHTYVQAMLLVLLYSQPKSAIVLGLGGGGLIHA
LRHFDAGIKLTAVELRADVIELAKRYFQLPLSKKLKVINQDAKLFLESGDHKRVDVIFADIYSADGVDAAQVSESFIAQC
AALIKADGYLVLNCWKEHSQNRELLAYLNRYFVEVRACLTGSGNWVVFAGKAKREISASGLKTKAQALSQQLDFQLGRSL
TRFDVWQ
>Mature_246_residues
SDFQTLHQTQDEYGPLIVLEDKETRILAFGENDEQSKLLKATPHIPQHTYVQAMLLVLLYSQPKSAIVLGLGGGGLIHAL
RHFDAGIKLTAVELRADVIELAKRYFQLPLSKKLKVINQDAKLFLESGDHKRVDVIFADIYSADGVDAAQVSESFIAQCA
ALIKADGYLVLNCWKEHSQNRELLAYLNRYFVEVRACLTGSGNWVVFAGKAKREISASGLKTKAQALSQQLDFQLGRSLT
RFDVWQ

Specific function: Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM), which serves as an aminopropyl donor [H]

COG id: COG0421

COG function: function code E; Spermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the spermidine/spermine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001045 [H]

Pfam domain/function: PF01564 Spermine_synth [H]

EC number: =2.5.1.16 [H]

Molecular weight: Translated: 27593; Mature: 27462

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFQTLHQTQDEYGPLIVLEDKETRILAFGENDEQSKLLKATPHIPQHTYVQAMLLVLL
CCCHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHH
YSQPKSAIVLGLGGGGLIHALRHFDAGIKLTAVELRADVIELAKRYFQLPLSKKLKVINQ
HCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCC
DAKLFLESGDHKRVDVIFADIYSADGVDAAQVSESFIAQCAALIKADGYLVLNCWKEHSQ
CHHEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCC
NRELLAYLNRYFVEVRACLTGSGNWVVFAGKAKREISASGLKTKAQALSQQLDFQLGRSL
CHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCH
TRFDVWQ
HHCCCCC
>Mature Secondary Structure 
SDFQTLHQTQDEYGPLIVLEDKETRILAFGENDEQSKLLKATPHIPQHTYVQAMLLVLL
CCHHHHHHHHHHHCCEEEEECCCCEEEEECCCCCHHHHHHCCCCCCCHHHHHHHHHHHH
YSQPKSAIVLGLGGGGLIHALRHFDAGIKLTAVELRADVIELAKRYFQLPLSKKLKVINQ
HCCCCCEEEEEECCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHCCHHHHHHHHCC
DAKLFLESGDHKRVDVIFADIYSADGVDAAQVSESFIAQCAALIKADGYLVLNCWKEHSQ
CHHEEEECCCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEEHHCCC
NRELLAYLNRYFVEVRACLTGSGNWVVFAGKAKREISASGLKTKAQALSQQLDFQLGRSL
CHHHHHHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHCCCH
TRFDVWQ
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]