Click here to switch to the map view.

The map label for this gene is ahpC [H]

Identifier: 157960574

GI number: 157960574

Start: 923053

End: 923622

Strand: Direct

Name: ahpC [H]

Synonym: Spea_0746

Alternate gene names: 157960574

Gene position: 923053-923622 (Clockwise)

Preceding gene: 157960573

Following gene: 157960575

Centisome position: 17.84

GC content: 46.49

Gene sequence:

>570_bases
ATGCATCAGTCAATCATCAACTCTACAATCAAGCCATTCTCTGCAACTGCTTTTCACAACGGTGACTTCCACCCAGTGAC
TGAGCAAGACCTACTAGGTAAGTGGTCAGTAGTATTCTTCTACCCAGCTGACTTCACATTCGTATGTCCAACTGAGCTAG
GCGACATGGCTGACCATTACGAGAAGCTACAGTCTATGGGCGTTGAAGTTTACTCAGTATCGACTGACACTCACTTCACT
CACAAAGCATGGCACTCAAGCTCTGACACAATCGGTAAAATCCAGTACCCAATGATTGGTGACCCAACTGGTACTATCAC
ACGTAACTTCGGTGTGATGATTGAGGAAGACGGTCTAGCACTACGTGGCACGTTTGTTATCAACCCAGAAGGCGAGATCA
AAGTTGCTGAAGTACATGACCTAGGTATTGGTCGTAGCGCAGCTGAACTAGTTCGTAAAATTCAAGCAGCTCAGTATGTT
GCAACTCACGACGGTGAAGTTTGCCCAGCAGCATGGCAGCCAGGTGAAGCGACTCTAGCTCCTTCAATTGACCTTGTTGG
TAAGATTTAA

Upstream 100 bases:

>100_bases
ACTGGCTTTAAGAGACTCATCATCACTCATTCAGTTTGTTGAATTTTAAGAAATAGTATTTTCAACTTTAATGATTAAAA
CAGATAAAACGGAGCATCAC

Downstream 100 bases:

>100_bases
TTAGTCGACAGTCAATAGATGATAGCGTGTTAGCGAGCCCCATCTCTCGCTAACATTCAACAAAGTCATCAAGAGATTTC
ATCTCCAGTGTTCAGCCTAG

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 189; Mature: 189

Protein sequence:

>189_residues
MHQSIINSTIKPFSATAFHNGDFHPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHYEKLQSMGVEVYSVSTDTHFT
HKAWHSSSDTIGKIQYPMIGDPTGTITRNFGVMIEEDGLALRGTFVINPEGEIKVAEVHDLGIGRSAAELVRKIQAAQYV
ATHDGEVCPAAWQPGEATLAPSIDLVGKI

Sequences:

>Translated_189_residues
MHQSIINSTIKPFSATAFHNGDFHPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHYEKLQSMGVEVYSVSTDTHFT
HKAWHSSSDTIGKIQYPMIGDPTGTITRNFGVMIEEDGLALRGTFVINPEGEIKVAEVHDLGIGRSAAELVRKIQAAQYV
ATHDGEVCPAAWQPGEATLAPSIDLVGKI
>Mature_189_residues
MHQSIINSTIKPFSATAFHNGDFHPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHYEKLQSMGVEVYSVSTDTHFT
HKAWHSSSDTIGKIQYPMIGDPTGTITRNFGVMIEEDGLALRGTFVINPEGEIKVAEVHDLGIGRSAAELVRKIQAAQYV
ATHDGEVCPAAWQPGEATLAPSIDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=45.6647398843931, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=45.6647398843931, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=42.2857142857143, Blast_Score=155, Evalue=2e-38,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=40, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=40, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=40, Blast_Score=149, Evalue=1e-36,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=39.5833333333333, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI33188454, Length=73, Percent_Identity=49.3150684931507, Blast_Score=80, Evalue=1e-15,
Organism=Escherichia coli, GI1786822, Length=186, Percent_Identity=69.8924731182796, Blast_Score=282, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17554494, Length=180, Percent_Identity=40.5555555555556, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI32565831, Length=186, Percent_Identity=38.7096774193548, Blast_Score=151, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193204376, Length=186, Percent_Identity=38.7096774193548, Blast_Score=151, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=24.390243902439, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320661, Length=175, Percent_Identity=34.8571428571429, Blast_Score=132, Evalue=3e-32,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=36.5714285714286, Blast_Score=131, Evalue=8e-32,
Organism=Saccharomyces cerevisiae, GI6319407, Length=165, Percent_Identity=29.0909090909091, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=38.9830508474576, Blast_Score=152, Evalue=1e-37,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=38.7434554973822, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24656348, Length=183, Percent_Identity=39.8907103825137, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI17864676, Length=183, Percent_Identity=39.8907103825137, Blast_Score=150, Evalue=4e-37,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=40, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=40, Blast_Score=144, Evalue=2e-35,
Organism=Drosophila melanogaster, GI24652436, Length=163, Percent_Identity=30.0613496932515, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=29.746835443038, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=29.746835443038, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24581278, Length=159, Percent_Identity=30.188679245283, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20680; Mature: 20680

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHQSIINSTIKPFSATAFHNGDFHPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHY
CCCHHHHHCCCCCEEEEEECCCCCCCCCHHHCCCEEEEEEECCCEEEECCHHHHHHHHHH
EKLQSMGVEVYSVSTDTHFTHKAWHSSSDTIGKIQYPMIGDPTGTITRNFGVMIEEDGLA
HHHHHCCEEEEEEECCCCEEEHHHCCCCCCEEEEECCCCCCCCCCEEECCCEEEECCCEE
LRGTFVINPEGEIKVAEVHDLGIGRSAAELVRKIQAAQYVATHDGEVCPAAWQPGEATLA
EEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEC
PSIDLVGKI
CCEEEEECC
>Mature Secondary Structure
MHQSIINSTIKPFSATAFHNGDFHPVTEQDLLGKWSVVFFYPADFTFVCPTELGDMADHY
CCCHHHHHCCCCCEEEEEECCCCCCCCCHHHCCCEEEEEEECCCEEEECCHHHHHHHHHH
EKLQSMGVEVYSVSTDTHFTHKAWHSSSDTIGKIQYPMIGDPTGTITRNFGVMIEEDGLA
HHHHHCCEEEEEEECCCCEEEHHHCCCCCCEEEEECCCCCCCCCCEEECCCEEEECCCEE
LRGTFVINPEGEIKVAEVHDLGIGRSAAELVRKIQAAQYVATHDGEVCPAAWQPGEATLA
EEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCEEC
PSIDLVGKI
CCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]