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The map label for this gene is regB [H]

Identifier: 157960381

GI number: 157960381

Start: 678668

End: 679990

Strand: Direct

Name: regB [H]

Synonym: Spea_0552

Alternate gene names: 157960381

Gene position: 678668-679990 (Clockwise)

Preceding gene: 157960380

Following gene: 157960382

Centisome position: 13.12

GC content: 50.42

Gene sequence:

>1323_bases
ATGATAACAATGAGCCCCATGATGAATACACGTTTTAAAAATCTACTGATACGTAATCTTGGGGCAACCGATCAATTAGC
ATTGTTGAGATTTGGCGCTCTCTTGCTGAAGATAGGCTTAACCTTTTTTGCTGCAGACACCTTTGGCTTATCGCTTACTA
GCCCGGTTCTCTACTGGGGAATGAGCCTAGAGGCTCTCTATTTAGGTTTTACTTTCTGGCACCGTAGCTCGATTGCTCGC
CTGGATAACGGTTTTTTCATCGTGTTGCTGATTGATACCCTGTTTTGGATCTCCTGGCTCTATTTTACCGGAGGGGCTAC
GAATGCATTTATCTCTTTGTTGCTGCTACCGATTGCAATTGCCGCAGTGGTACTTCCTCAGTGGGCGCCCTGGGCCTTAG
CTCTGTTGTCGACTTTCGCCTATAGCTTGATGATTTTTTCTGTGCCCGAGAGCCAGATGAAGCACCATGGCATGGATATG
AGTTCTCACTATCTAGGCATGTGGTTTAACTTCCTGATTTCGGCGTTAGTGCTGACTACCAGTGTGGCCTATATTGCCCA
ACGCATGCGTAAACAAGAGGTTGAGCTAGGTTATATGCGCGAGGCCCAGCTACGTCAAGAAAGGCTATTAGCGCTTGGTA
CGGCCTCGGCACAAATGGCCCACCAATTAGCCACGCCGTTGGCGAGTCTACGTTTGCTGGTGGATGAAGCCGTTGAAGAG
CAAACCAGTGAGCCTGAAATTTTACAGGAGATGAACACGGCATTAGTCCGCTGTGAGCAGACGCTAAACTCGCTGCGAAT
GGCCACTGAGTCTATTCGTGAGCAGAGACAGAGCTTGTTAACGGCCCATGAACTGCTGTCAACGCTCGAGCAGCAAGTGC
TGTTGTTAATGCCAGAAGTTACCTTAGAGCTTAAGTTTTGTGAGCGCGCTGCCGCGCAGGCTGCAGAAAGTGCAGTGATT
AAGACCGATGCCAGTCTGCTCCCCGCGCTACTGGCATTAGTTGAAAATGCCAGTAGCGCCAGTCAAGCCTATACCGGTGA
AGCCCGAGTGGTGGTATCGGCCCTAGTTGGAGGGGATAGCGATCGACTCTGTGTTTCAGTTAAAGATTTTGGCGCGGGGA
TCCCCAAAGAGATGCAGCTGCAGCTGGGGCGCAAGTTGATTGAGAGTGAGCGTGGCATGGGCATGGCACTGCTCTTAAGT
AACGCGAGCTTCGAGCGCTTGGGGGGGCAGTTACTTCTGGGTAGCGCTAAAGAGGGAGGCACTGTTGCCCAAGTATGTTT
CCCTGTTTGGACTGGCGATACAGATGGAGAGTGTCATGAATAA

Upstream 100 bases:

>100_bases
CCTTTTAAGGTCGGAATAGAGAGCGCCTTGTTGCAGTCTTCAGTTGTACAGCAATGGCTTGCTCAAAGATGAAAACGATA
ACAATAAAGAATGATTACCC

Downstream 100 bases:

>100_bases
TAAGCTGCTCATTATTGAAGATGATACGGCTTTAGCAAACGTGCTGGCTCGCCGTATGACTAAGCAAGGATTTGAGTGTC
AGCAGTGTCACGATGCCAGC

Product: histidine kinase

Products: NA

Alternate protein names: Protein prrB [H]

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MITMSPMMNTRFKNLLIRNLGATDQLALLRFGALLLKIGLTFFAADTFGLSLTSPVLYWGMSLEALYLGFTFWHRSSIAR
LDNGFFIVLLIDTLFWISWLYFTGGATNAFISLLLLPIAIAAVVLPQWAPWALALLSTFAYSLMIFSVPESQMKHHGMDM
SSHYLGMWFNFLISALVLTTSVAYIAQRMRKQEVELGYMREAQLRQERLLALGTASAQMAHQLATPLASLRLLVDEAVEE
QTSEPEILQEMNTALVRCEQTLNSLRMATESIREQRQSLLTAHELLSTLEQQVLLLMPEVTLELKFCERAAAQAAESAVI
KTDASLLPALLALVENASSASQAYTGEARVVVSALVGGDSDRLCVSVKDFGAGIPKEMQLQLGRKLIESERGMGMALLLS
NASFERLGGQLLLGSAKEGGTVAQVCFPVWTGDTDGECHE

Sequences:

>Translated_440_residues
MITMSPMMNTRFKNLLIRNLGATDQLALLRFGALLLKIGLTFFAADTFGLSLTSPVLYWGMSLEALYLGFTFWHRSSIAR
LDNGFFIVLLIDTLFWISWLYFTGGATNAFISLLLLPIAIAAVVLPQWAPWALALLSTFAYSLMIFSVPESQMKHHGMDM
SSHYLGMWFNFLISALVLTTSVAYIAQRMRKQEVELGYMREAQLRQERLLALGTASAQMAHQLATPLASLRLLVDEAVEE
QTSEPEILQEMNTALVRCEQTLNSLRMATESIREQRQSLLTAHELLSTLEQQVLLLMPEVTLELKFCERAAAQAAESAVI
KTDASLLPALLALVENASSASQAYTGEARVVVSALVGGDSDRLCVSVKDFGAGIPKEMQLQLGRKLIESERGMGMALLLS
NASFERLGGQLLLGSAKEGGTVAQVCFPVWTGDTDGECHE
>Mature_440_residues
MITMSPMMNTRFKNLLIRNLGATDQLALLRFGALLLKIGLTFFAADTFGLSLTSPVLYWGMSLEALYLGFTFWHRSSIAR
LDNGFFIVLLIDTLFWISWLYFTGGATNAFISLLLLPIAIAAVVLPQWAPWALALLSTFAYSLMIFSVPESQMKHHGMDM
SSHYLGMWFNFLISALVLTTSVAYIAQRMRKQEVELGYMREAQLRQERLLALGTASAQMAHQLATPLASLRLLVDEAVEE
QTSEPEILQEMNTALVRCEQTLNSLRMATESIREQRQSLLTAHELLSTLEQQVLLLMPEVTLELKFCERAAAQAAESAVI
KTDASLLPALLALVENASSASQAYTGEARVVVSALVGGDSDRLCVSVKDFGAGIPKEMQLQLGRKLIESERGMGMALLLS
NASFERLGGQLLLGSAKEGGTVAQVCFPVWTGDTDGECHE

Specific function: Member of the two-component regulatory system RegB/RegA. Involved in the positive regulation of photosynthesis gene expression in response to anaerobiosis. Also involved in positive regulation of the cbbI and cbbII Calvin cycle CO2 fixation operons, as we

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48428; Mature: 48428

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITMSPMMNTRFKNLLIRNLGATDQLALLRFGALLLKIGLTFFAADTFGLSLTSPVLYWG
CEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHHC
MSLEALYLGFTFWHRSSIARLDNGFFIVLLIDTLFWISWLYFTGGATNAFISLLLLPIAI
CHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AAVVLPQWAPWALALLSTFAYSLMIFSVPESQMKHHGMDMSSHYLGMWFNFLISALVLTT
HHHHHCCCCHHHHHHHHHHHHHHHHEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SVAYIAQRMRKQEVELGYMREAQLRQERLLALGTASAQMAHQLATPLASLRLLVDEAVEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QTSEPEILQEMNTALVRCEQTLNSLRMATESIREQRQSLLTAHELLSTLEQQVLLLMPEV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TLELKFCERAAAQAAESAVIKTDASLLPALLALVENASSASQAYTGEARVVVSALVGGDS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCC
DRLCVSVKDFGAGIPKEMQLQLGRKLIESERGMGMALLLSNASFERLGGQLLLGSAKEGG
CCEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCEEEEECCCCCC
TVAQVCFPVWTGDTDGECHE
CEEHHEEEEECCCCCCCCCC
>Mature Secondary Structure
MITMSPMMNTRFKNLLIRNLGATDQLALLRFGALLLKIGLTFFAADTFGLSLTSPVLYWG
CEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCHHHHHC
MSLEALYLGFTFWHRSSIARLDNGFFIVLLIDTLFWISWLYFTGGATNAFISLLLLPIAI
CHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AAVVLPQWAPWALALLSTFAYSLMIFSVPESQMKHHGMDMSSHYLGMWFNFLISALVLTT
HHHHHCCCCHHHHHHHHHHHHHHHHEECCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
SVAYIAQRMRKQEVELGYMREAQLRQERLLALGTASAQMAHQLATPLASLRLLVDEAVEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
QTSEPEILQEMNTALVRCEQTLNSLRMATESIREQRQSLLTAHELLSTLEQQVLLLMPEV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
TLELKFCERAAAQAAESAVIKTDASLLPALLALVENASSASQAYTGEARVVVSALVGGDS
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCC
DRLCVSVKDFGAGIPKEMQLQLGRKLIESERGMGMALLLSNASFERLGGQLLLGSAKEGG
CCEEEEEHHHCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHCCCEEEEECCCCCC
TVAQVCFPVWTGDTDGECHE
CEEHHEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7751278; 10358089 [H]