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The map label for this gene is regA [H]

Identifier: 157960382

GI number: 157960382

Start: 679983

End: 680522

Strand: Direct

Name: regA [H]

Synonym: Spea_0553

Alternate gene names: 157960382

Gene position: 679983-680522 (Clockwise)

Preceding gene: 157960381

Following gene: 157960385

Centisome position: 13.14

GC content: 46.3

Gene sequence:

>540_bases
ATGAATAATAAGCTGCTCATTATTGAAGATGATACGGCTTTAGCAAACGTGCTGGCTCGCCGTATGACTAAGCAAGGATT
TGAGTGTCAGCAGTGTCACGATGCCAGCCAAGGCTTGTTGCTAGCTAGGCAATTTCGTCCGACTCATGTGTTGTTAGACA
TGAAGTTAGAGCAGGAAAACGGCCTTAAGTTGATCTCGCCATTGAGACAATTACTCCCGGATGTGACTATGGTACTGTTA
ACGGGATATGCCAGCATAGCGACTGCTGTGGAGGCTATCAGATTGGGCGCCGATAACTATTTGGCAAAACCTGTCGATAC
GCAAACCCTGTTAAGTGCGTTATCGGTGACGTCATTTGATAATGATATGGATCCATTAGTCGAGGAGCCATTATCGCCTA
AACGTTTAGAGTGGGAGCATATTCAGCAGGTGCTAAATGTCAACCGCGGCAACGTTTCAGCTACTGCTAGGCAGCTTGGG
ATGCATAGACGAACTTTACAGCGTAAATTATTAAAGAAGCCGACGGCGGATCATCGTTAG

Upstream 100 bases:

>100_bases
CGCTTGGGGGGGCAGTTACTTCTGGGTAGCGCTAAAGAGGGAGGCACTGTTGCCCAAGTATGTTTCCCTGTTTGGACTGG
CGATACAGATGGAGAGTGTC

Downstream 100 bases:

>100_bases
GCCTAATGTCGTCCATTTTGCACTTAGAGTGTGATGTATTTAAGGTGAGGGAAATCATAGACTTGTTGCTGAGCGAGTAT
TGCTGTGGCTTAGCGATGAC

Product: two component Fis family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MNNKLLIIEDDTALANVLARRMTKQGFECQQCHDASQGLLLARQFRPTHVLLDMKLEQENGLKLISPLRQLLPDVTMVLL
TGYASIATAVEAIRLGADNYLAKPVDTQTLLSALSVTSFDNDMDPLVEEPLSPKRLEWEHIQQVLNVNRGNVSATARQLG
MHRRTLQRKLLKKPTADHR

Sequences:

>Translated_179_residues
MNNKLLIIEDDTALANVLARRMTKQGFECQQCHDASQGLLLARQFRPTHVLLDMKLEQENGLKLISPLRQLLPDVTMVLL
TGYASIATAVEAIRLGADNYLAKPVDTQTLLSALSVTSFDNDMDPLVEEPLSPKRLEWEHIQQVLNVNRGNVSATARQLG
MHRRTLQRKLLKKPTADHR
>Mature_179_residues
MNNKLLIIEDDTALANVLARRMTKQGFECQQCHDASQGLLLARQFRPTHVLLDMKLEQENGLKLISPLRQLLPDVTMVLL
TGYASIATAVEAIRLGADNYLAKPVDTQTLLSALSVTSFDNDMDPLVEEPLSPKRLEWEHIQQVLNVNRGNVSATARQLG
MHRRTLQRKLLKKPTADHR

Specific function: Member of the two-component regulatory system regB/regA. Involved in transactivating anaerobic expression of the photosynthetic apparatus. It is a transcriptional regulator that is responsible for activating expression of the puf, puh, and puc operons in

COG id: COG4567

COG function: function code TK; Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=108, Percent_Identity=32.4074074074074, Blast_Score=70, Evalue=6e-14,
Organism=Escherichia coli, GI1790437, Length=113, Percent_Identity=28.3185840707965, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 20145; Mature: 20145

Theoretical pI: Translated: 8.75; Mature: 8.75

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNKLLIIEDDTALANVLARRMTKQGFECQQCHDASQGLLLARQFRPTHVLLDMKLEQEN
CCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHCCCEEEEEEEEECCCC
GLKLISPLRQLLPDVTMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLLSALSVTSFD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
NDMDPLVEEPLSPKRLEWEHIQQVLNVNRGNVSATARQLGMHRRTLQRKLLKKPTADHR
CCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MNNKLLIIEDDTALANVLARRMTKQGFECQQCHDASQGLLLARQFRPTHVLLDMKLEQEN
CCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHCCCEEEEEEEEECCCC
GLKLISPLRQLLPDVTMVLLTGYASIATAVEAIRLGADNYLAKPVDTQTLLSALSVTSFD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCC
NDMDPLVEEPLSPKRLEWEHIQQVLNVNRGNVSATARQLGMHRRTLQRKLLKKPTADHR
CCCCHHHHCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1547494 [H]