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The map label for this gene is coaE [H]

Identifier: 157960239

GI number: 157960239

Start: 502382

End: 502987

Strand: Reverse

Name: coaE [H]

Synonym: Spea_0410

Alternate gene names: 157960239

Gene position: 502987-502382 (Counterclockwise)

Preceding gene: 157960240

Following gene: 157960238

Centisome position: 9.72

GC content: 41.09

Gene sequence:

>606_bases
ATGGCTGATTTTATAGTTGGGCTAACAGGCGGTATAGGAAGTGGCAAAACTACCGTCGCCAATCTCTTTGCTGAACTCGG
CATTTCGCTCGTCGATGCCGATATCATCGCCCGTGATGTTGTAGCAAAGGGTTCTACAGGACTTATTAAAATTGTTGAGC
ACTTCGGTGCTGACACACTTTTAGCAGACGGCAACCTAGATCGCTCAAAGCTTAGAGATAAAATTTTTTCTGATGATTCT
GAACGAGTCTGGTTAAATAACCTATTACACCCAATGATCAGAGAATCTATGCTGCAACAATGCAAAGATGCTCAAACAGA
TTACGTAATTATGGTCGTGCCCTTGCTATTTGAGAACGGGTTAGATAGGTTAGTAGATCGAACACTTGTGGTGGATATTT
CACCTAAACTGCAGCAACAAAGAACCATAAGCAGAGATGCGGTTACTGCAGAACAAGTAAAAAATATAATAGGCAGTCAG
GCTTCTAGAGCCGAGAAACTGTCAAAAGCTGATGATGTCATAGACAATCAAGGAGAGATATCGGCGTTAAAGTGCAAGGT
ACTCGCACTACATAACTTTTATTTAAAATTAGCCAGTAATTCTTGA

Upstream 100 bases:

>100_bases
GGACCTTACATCGCTGCTGCAGGCTGGATAGCCATGATCTGGGGCGAGAGCATTACCAACTGGTATCTGTCCACTTTATA
ATGGCTATGAGGTAAAAACT

Downstream 100 bases:

>100_bases
ATAACGCCATGACTGAATTGATCTATGAACAGCCTTTGAACGAAAAAACTCGTAGCTACCTGCGCCTAGAATATTTAGCG
CAGCAGCTGCAGGCCAACCT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 201; Mature: 200

Protein sequence:

>201_residues
MADFIVGLTGGIGSGKTTVANLFAELGISLVDADIIARDVVAKGSTGLIKIVEHFGADTLLADGNLDRSKLRDKIFSDDS
ERVWLNNLLHPMIRESMLQQCKDAQTDYVIMVVPLLFENGLDRLVDRTLVVDISPKLQQQRTISRDAVTAEQVKNIIGSQ
ASRAEKLSKADDVIDNQGEISALKCKVLALHNFYLKLASNS

Sequences:

>Translated_201_residues
MADFIVGLTGGIGSGKTTVANLFAELGISLVDADIIARDVVAKGSTGLIKIVEHFGADTLLADGNLDRSKLRDKIFSDDS
ERVWLNNLLHPMIRESMLQQCKDAQTDYVIMVVPLLFENGLDRLVDRTLVVDISPKLQQQRTISRDAVTAEQVKNIIGSQ
ASRAEKLSKADDVIDNQGEISALKCKVLALHNFYLKLASNS
>Mature_200_residues
ADFIVGLTGGIGSGKTTVANLFAELGISLVDADIIARDVVAKGSTGLIKIVEHFGADTLLADGNLDRSKLRDKIFSDDSE
RVWLNNLLHPMIRESMLQQCKDAQTDYVIMVVPLLFENGLDRLVDRTLVVDISPKLQQQRTISRDAVTAEQVKNIIGSQA
SRAEKLSKADDVIDNQGEISALKCKVLALHNFYLKLASNS

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=193, Percent_Identity=37.3056994818653, Blast_Score=123, Evalue=9e-29,
Organism=Homo sapiens, GI191252795, Length=193, Percent_Identity=37.3056994818653, Blast_Score=123, Evalue=9e-29,
Organism=Homo sapiens, GI110227605, Length=180, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227603, Length=180, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227601, Length=180, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI110227607, Length=163, Percent_Identity=28.2208588957055, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI205277394, Length=180, Percent_Identity=26.6666666666667, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1786292, Length=196, Percent_Identity=53.0612244897959, Blast_Score=209, Evalue=9e-56,
Organism=Caenorhabditis elegans, GI17554944, Length=189, Percent_Identity=36.5079365079365, Blast_Score=117, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25143409, Length=171, Percent_Identity=30.4093567251462, Blast_Score=73, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=181, Percent_Identity=36.4640883977901, Blast_Score=100, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24644728, Length=193, Percent_Identity=33.6787564766839, Blast_Score=111, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24658602, Length=180, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977
- InterPro:   IPR000764 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21967; Mature: 21835

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFIVGLTGGIGSGKTTVANLFAELGISLVDADIIARDVVAKGSTGLIKIVEHFGADTL
CCCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEE
LADGNLDRSKLRDKIFSDDSERVWLNNLLHPMIRESMLQQCKDAQTDYVIMVVPLLFENG
EECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCC
LDRLVDRTLVVDISPKLQQQRTISRDAVTAEQVKNIIGSQASRAEKLSKADDVIDNQGEI
HHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
SALKCKVLALHNFYLKLASNS
HHHHHHHHHHHHHHHEECCCC
>Mature Secondary Structure 
ADFIVGLTGGIGSGKTTVANLFAELGISLVDADIIARDVVAKGSTGLIKIVEHFGADTL
CCEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEE
LADGNLDRSKLRDKIFSDDSERVWLNNLLHPMIRESMLQQCKDAQTDYVIMVVPLLFENG
EECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHCC
LDRLVDRTLVVDISPKLQQQRTISRDAVTAEQVKNIIGSQASRAEKLSKADDVIDNQGEI
HHHHHCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCC
SALKCKVLALHNFYLKLASNS
HHHHHHHHHHHHHHHEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]