Click here to switch to the map view.

The map label for this gene is arlS [H]

Identifier: 157960163

GI number: 157960163

Start: 376866

End: 378122

Strand: Reverse

Name: arlS [H]

Synonym: Spea_0334

Alternate gene names: 157960163

Gene position: 378122-376866 (Counterclockwise)

Preceding gene: 157960164

Following gene: 157960161

Centisome position: 7.31

GC content: 45.27

Gene sequence:

>1257_bases
ATGGACAAGGTTACCGCCTCAAAGCATAAACAGTTCCCGAGCATCTACCGCAAGCTCCGTTGGAGCTTCGGTTTGATGAC
CTTTGCTATGTTTAGCCTATTTTGGTCGGTGATCTATATTGCCGAAAACCAGATTGAAAAGATCAGTCTCAATCACTGGC
TAGACACCGAAGTATATCGGTATAAACAGGACTACAAGATTTATGGCGAAAAAACGGTTCTACCCAATACCAATGAGTTT
ACTACCTACTGGAGTGAGCAAACCATTCCAGAGTGGCTCAATGCTTATACTTCACCAGGCCTATATGAAAAGTTAATAGG
AGAAGAAGATAAGCACTTTATTGTTTCTCTTCACCCTTCCGGTAAAGGCTTAATGTATGTTGTGTTTCAAGATGATGCCG
ATGACTATCTTGATGAATATGAAGAACATCTGCATGATTATGTACTCATACTAGGCCTACTTATTGGTCTATTAATGACG
ATTTATAGTCTGTACTTTATCCGCACCCTATCCAAGCCATTGACAATCATTGAGCACAAGATCACCCAGATGTCGCCAGA
TGACCCGCCTTTCGGTGTCGATACCCGCTTTGTCGAGACCCGTAATATCGAACAAACTTTGCTAGATAGTCGCAATGATA
TCAACGGATTCTTTCAACGAGAGAAAGAGTTTAGCCACTTTGCTTCCCACGAGCTCAGAACCCCGATTACCGTGATAAAA
GGCTCAGCAGAACTATTGGCTAAAATACCAGACCAGCATCCACTGGCAGTCAACGCCGTTAAGCGCCTGCAACGGGCCAG
CGACGAGATGCAGGTGCTCACCGAAACTTTTCTATTATTGGGTAAAGAGTCGATTAGCCAGCGTCACTTCGCCGATGTCA
GCCTAGAGGGCGCGCTATGTAAGCAGCTCGCCGAGATGAAAGAGTTATTCGCCAGACAAGACAGCAGTTATTGCTTAACG
GTCAATGAGGCTAAGAGTGTCCATGCCCCAGACAGCTTTATTGCCATCGTGCTCAACAATGTCATTAAGAATGCTTTCAG
TTACAGCATAGGTGACATTGAAATCGTGCTTAATCAGCACACCTTAACCATCACCAATCGCCACGAAGGCAATGAAACCT
ACAATGCGGGCTATGGTGTTGGACTGGTCATCGTCGAGCGCATCTGCGAACGCATGGGGTGGAGTTATCTGCCTCATGAT
AACGGAGTTGAGTTTCAAACAACCTTGGTATTTTCTGCCAAAGGGGAGACCCTTTAG

Upstream 100 bases:

>100_bases
GGGGATGAGTCTCCTCCGAGTGATGCCTTGCGTAGTCATATTTACGGCCTGCGAACCGCCCTTGACAAAGGCTTCGAACA
ATCACGATTAGAGACGATTC

Downstream 100 bases:

>100_bases
GTGTGGTTTCATTTGCGTGAAACTAACGCAGGCTTTAAATCTAAAGCATGCGAACCTTTGGCTTCATTGTCATTTGAAGC
TATGTAACAACTTCCTGCAT

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MDKVTASKHKQFPSIYRKLRWSFGLMTFAMFSLFWSVIYIAENQIEKISLNHWLDTEVYRYKQDYKIYGEKTVLPNTNEF
TTYWSEQTIPEWLNAYTSPGLYEKLIGEEDKHFIVSLHPSGKGLMYVVFQDDADDYLDEYEEHLHDYVLILGLLIGLLMT
IYSLYFIRTLSKPLTIIEHKITQMSPDDPPFGVDTRFVETRNIEQTLLDSRNDINGFFQREKEFSHFASHELRTPITVIK
GSAELLAKIPDQHPLAVNAVKRLQRASDEMQVLTETFLLLGKESISQRHFADVSLEGALCKQLAEMKELFARQDSSYCLT
VNEAKSVHAPDSFIAIVLNNVIKNAFSYSIGDIEIVLNQHTLTITNRHEGNETYNAGYGVGLVIVERICERMGWSYLPHD
NGVEFQTTLVFSAKGETL

Sequences:

>Translated_418_residues
MDKVTASKHKQFPSIYRKLRWSFGLMTFAMFSLFWSVIYIAENQIEKISLNHWLDTEVYRYKQDYKIYGEKTVLPNTNEF
TTYWSEQTIPEWLNAYTSPGLYEKLIGEEDKHFIVSLHPSGKGLMYVVFQDDADDYLDEYEEHLHDYVLILGLLIGLLMT
IYSLYFIRTLSKPLTIIEHKITQMSPDDPPFGVDTRFVETRNIEQTLLDSRNDINGFFQREKEFSHFASHELRTPITVIK
GSAELLAKIPDQHPLAVNAVKRLQRASDEMQVLTETFLLLGKESISQRHFADVSLEGALCKQLAEMKELFARQDSSYCLT
VNEAKSVHAPDSFIAIVLNNVIKNAFSYSIGDIEIVLNQHTLTITNRHEGNETYNAGYGVGLVIVERICERMGWSYLPHD
NGVEFQTTLVFSAKGETL
>Mature_418_residues
MDKVTASKHKQFPSIYRKLRWSFGLMTFAMFSLFWSVIYIAENQIEKISLNHWLDTEVYRYKQDYKIYGEKTVLPNTNEF
TTYWSEQTIPEWLNAYTSPGLYEKLIGEEDKHFIVSLHPSGKGLMYVVFQDDADDYLDEYEEHLHDYVLILGLLIGLLMT
IYSLYFIRTLSKPLTIIEHKITQMSPDDPPFGVDTRFVETRNIEQTLLDSRNDINGFFQREKEFSHFASHELRTPITVIK
GSAELLAKIPDQHPLAVNAVKRLQRASDEMQVLTETFLLLGKESISQRHFADVSLEGALCKQLAEMKELFARQDSSYCLT
VNEAKSVHAPDSFIAIVLNNVIKNAFSYSIGDIEIVLNQHTLTITNRHEGNETYNAGYGVGLVIVERICERMGWSYLPHD
NGVEFQTTLVFSAKGETL

Specific function: Member of the two-component regulatory system ArlS/ArlR. ArlS probably functions as a sensor protein kinase which is autophosphorylated at a histidine residue and transfers its phosphate group to ArlR [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48142; Mature: 48142

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKVTASKHKQFPSIYRKLRWSFGLMTFAMFSLFWSVIYIAENQIEKISLNHWLDTEVYR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHH
YKQDYKIYGEKTVLPNTNEFTTYWSEQTIPEWLNAYTSPGLYEKLIGEEDKHFIVSLHPS
HHHCEEEECCEEECCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHCCCCCCEEEEEECCC
GKGLMYVVFQDDADDYLDEYEEHLHDYVLILGLLIGLLMTIYSLYFIRTLSKPLTIIEHK
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ITQMSPDDPPFGVDTRFVETRNIEQTLLDSRNDINGFFQREKEFSHFASHELRTPITVIK
HHHCCCCCCCCCCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEC
GSAELLAKIPDQHPLAVNAVKRLQRASDEMQVLTETFLLLGKESISQRHFADVSLEGALC
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KQLAEMKELFARQDSSYCLTVNEAKSVHAPDSFIAIVLNNVIKNAFSYSIGDIEIVLNQH
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECE
TLTITNRHEGNETYNAGYGVGLVIVERICERMGWSYLPHDNGVEFQTTLVFSAKGETL
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCC
>Mature Secondary Structure
MDKVTASKHKQFPSIYRKLRWSFGLMTFAMFSLFWSVIYIAENQIEKISLNHWLDTEVYR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEEECCCCCCHHHHH
YKQDYKIYGEKTVLPNTNEFTTYWSEQTIPEWLNAYTSPGLYEKLIGEEDKHFIVSLHPS
HHHCEEEECCEEECCCCCCCEEECCCCCHHHHHHHHCCCCHHHHHCCCCCCEEEEEECCC
GKGLMYVVFQDDADDYLDEYEEHLHDYVLILGLLIGLLMTIYSLYFIRTLSKPLTIIEHK
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
ITQMSPDDPPFGVDTRFVETRNIEQTLLDSRNDINGFFQREKEFSHFASHELRTPITVIK
HHHCCCCCCCCCCCCCEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEC
GSAELLAKIPDQHPLAVNAVKRLQRASDEMQVLTETFLLLGKESISQRHFADVSLEGALC
CCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
KQLAEMKELFARQDSSYCLTVNEAKSVHAPDSFIAIVLNNVIKNAFSYSIGDIEIVLNQH
HHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECE
TLTITNRHEGNETYNAGYGVGLVIVERICERMGWSYLPHDNGVEFQTTLVFSAKGETL
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA