Click here to switch to the map view.

The map label for this gene is coaA [H]

Identifier: 157959999

GI number: 157959999

Start: 190429

End: 191379

Strand: Reverse

Name: coaA [H]

Synonym: Spea_0169

Alternate gene names: 157959999

Gene position: 191379-190429 (Counterclockwise)

Preceding gene: 157960040

Following gene: 157959996

Centisome position: 3.7

GC content: 39.64

Gene sequence:

>951_bases
ATGTCGCAACCAAACCAAATTCACAATGCTCTTTACCTCGCATTTCAGCGCCTACAGTGGTCAGGACTAAGGGAATCAGT
TCCTTTAACACTTAGCGAAAATGATTTGGCAGATTTACGTGGTATTAATGAAAAAATATCCTTATCTGAAGTCACCGATA
TTTATCTGCCTTTAAGCCGACTACTTAACCTTAATGTTGGCGCAAAACAGCAAAGAGGCTTAGCACTTAATGAGTTCTTA
GGTCACGTCCCACCCAAACGTCCCTATATTATTAGTATTGCAGGCAGTGTTGCAGTAGGTAAAAGTACTACAGCCCGTAT
TTTGCAAGCTTTGCTAAGCCATTGGCCAGAACACCCAAAAGTTGACTTAATCACTACAGATGGCTTTTTATATCCATTAT
CCGAGCTAAAAAGACGAGGCCTGTTGCAACGTAAAGGCTTTCCAGAAAGTTACGATATGAAGGCGTTAGTGGAGTTTATT
TCAGCGATTAAAGCTGGTGAGCCTAATGTAAGTGCACCAATTTATTCGCATATAACTTATGACCGGATACAAGATGAACA
GCAATGGATCCGTCAACCAGATATTTTGATTATAGAAGGTCTCAATGTGTTACAGACAGGCCAAGACTCACCTGTTGATA
CACAACGTCCTTTCGTCTCTGATTTTGTCGACTTCTCGATATATGTCGATGCCAATGAGTCGCTATTAAAGAAATGGTAT
ATAGACAGGTTTTTACAATTTAGAACTGGTGCATTTAGCTCTGAAAATTCTTATTTCCATCATTATTCTAAGTTAGGGGA
TGAAGAGGCTACCGCAACAGCCTCTAATATTTGGGATACGATTAACGGACCAAATTTAACCTTAAATATTTTACCCACCC
GAGAAAGAGCACATCTTATTCTGCAAAAAGGACCTGACCATATGATGGACCAAGTCCTTTTGAGAAAATAG

Upstream 100 bases:

>100_bases
TAAAGCAAATTAGTGTTTAAAGCGAGCAGGCTCGTCTTCATTGCAGTTGTTCATAATAATTCCATAGTGTACTGTGCCCT
CCTGAACGGAGAACTTCGCA

Downstream 100 bases:

>100_bases
AATTCGGTTTCTATATTGTCTAAGTTGTTAGATTAGCCTAGCTTTCGTAGGCTAATCTCACCGCCAATAAAACTCTGTTT
TCCAGAGGCCGTCTCTAGCA

Product: pantothenate kinase

Products: NA

Alternate protein names: Pantothenic acid kinase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSQPNQIHNALYLAFQRLQWSGLRESVPLTLSENDLADLRGINEKISLSEVTDIYLPLSRLLNLNVGAKQQRGLALNEFL
GHVPPKRPYIISIAGSVAVGKSTTARILQALLSHWPEHPKVDLITTDGFLYPLSELKRRGLLQRKGFPESYDMKALVEFI
SAIKAGEPNVSAPIYSHITYDRIQDEQQWIRQPDILIIEGLNVLQTGQDSPVDTQRPFVSDFVDFSIYVDANESLLKKWY
IDRFLQFRTGAFSSENSYFHHYSKLGDEEATATASNIWDTINGPNLTLNILPTRERAHLILQKGPDHMMDQVLLRK

Sequences:

>Translated_316_residues
MSQPNQIHNALYLAFQRLQWSGLRESVPLTLSENDLADLRGINEKISLSEVTDIYLPLSRLLNLNVGAKQQRGLALNEFL
GHVPPKRPYIISIAGSVAVGKSTTARILQALLSHWPEHPKVDLITTDGFLYPLSELKRRGLLQRKGFPESYDMKALVEFI
SAIKAGEPNVSAPIYSHITYDRIQDEQQWIRQPDILIIEGLNVLQTGQDSPVDTQRPFVSDFVDFSIYVDANESLLKKWY
IDRFLQFRTGAFSSENSYFHHYSKLGDEEATATASNIWDTINGPNLTLNILPTRERAHLILQKGPDHMMDQVLLRK
>Mature_315_residues
SQPNQIHNALYLAFQRLQWSGLRESVPLTLSENDLADLRGINEKISLSEVTDIYLPLSRLLNLNVGAKQQRGLALNEFLG
HVPPKRPYIISIAGSVAVGKSTTARILQALLSHWPEHPKVDLITTDGFLYPLSELKRRGLLQRKGFPESYDMKALVEFIS
AIKAGEPNVSAPIYSHITYDRIQDEQQWIRQPDILIIEGLNVLQTGQDSPVDTQRPFVSDFVDFSIYVDANESLLKKWYI
DRFLQFRTGAFSSENSYFHHYSKLGDEEATATASNIWDTINGPNLTLNILPTRERAHLILQKGPDHMMDQVLLRK

Specific function: Coenzyme A (CoA) biosynthesis; first step. [C]

COG id: COG1072

COG function: function code H; Panthothenate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic pantothenate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1790409, Length=316, Percent_Identity=61.3924050632911, Blast_Score=390, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004566
- InterPro:   IPR006083 [H]

Pfam domain/function: PF00485 PRK [H]

EC number: =2.7.1.33 [H]

Molecular weight: Translated: 35879; Mature: 35748

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQPNQIHNALYLAFQRLQWSGLRESVPLTLSENDLADLRGINEKISLSEVTDIYLPLSR
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHH
LLNLNVGAKQQRGLALNEFLGHVPPKRPYIISIAGSVAVGKSTTARILQALLSHWPEHPK
HHCCCCCCCHHCCCCHHHHHHCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCC
VDLITTDGFLYPLSELKRRGLLQRKGFPESYDMKALVEFISAIKAGEPNVSAPIYSHITY
EEEEECCCCCCCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
DRIQDEQQWIRQPDILIIEGLNVLQTGQDSPVDTQRPFVSDFVDFSIYVDANESLLKKWY
HHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCCCCCCHHHHHCEEEEEECCCHHHHHHHH
IDRFLQFRTGAFSSENSYFHHYSKLGDEEATATASNIWDTINGPNLTLNILPTRERAHLI
HHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHEE
LQKGPDHMMDQVLLRK
EECCCHHHHHHHHHCC
>Mature Secondary Structure 
SQPNQIHNALYLAFQRLQWSGLRESVPLTLSENDLADLRGINEKISLSEVTDIYLPLSR
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCHHHHHCCCCCCCHHHHHHHHHHHHH
LLNLNVGAKQQRGLALNEFLGHVPPKRPYIISIAGSVAVGKSTTARILQALLSHWPEHPK
HHCCCCCCCHHCCCCHHHHHHCCCCCCCEEEEECCCEEECCCHHHHHHHHHHHHCCCCCC
VDLITTDGFLYPLSELKRRGLLQRKGFPESYDMKALVEFISAIKAGEPNVSAPIYSHITY
EEEEECCCCCCCHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHH
DRIQDEQQWIRQPDILIIEGLNVLQTGQDSPVDTQRPFVSDFVDFSIYVDANESLLKKWY
HHHHHHHHHHCCCCEEEEECCCHHCCCCCCCCCCCCCHHHHHCEEEEEECCCHHHHHHHH
IDRFLQFRTGAFSSENSYFHHYSKLGDEEATATASNIWDTINGPNLTLNILPTRERAHLI
HHHHHHHHCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHEE
LQKGPDHMMDQVLLRK
EECCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA