Click here to switch to the map view.

The map label for this gene is htpG [H]

Identifier: 157826314

GI number: 157826314

Start: 1165686

End: 1167551

Strand: Direct

Name: htpG [H]

Synonym: A1C_06515

Alternate gene names: 157826314

Gene position: 1165686-1167551 (Clockwise)

Preceding gene: 157826313

Following gene: 157826315

Centisome position: 94.69

GC content: 32.74

Gene sequence:

>1866_bases
ATGACACAAGAAAAGAAAAAGTTTGATGCCGAGGTCGGCAAGATTTTAAATTTAATGATTCACTCTCTGTATAGCAATAA
AGAGATTTTTATGAGGGAGTTAATTTCCAATGCTTCGGATGCTTGCGATAAATTACGTTATTTATCTCAAAGTCATAGCG
AATTAGTAGCTAGTGATAGTAATTTTAAAATTACGGTTAAAGTCGATAAAGATAACTGGCAGATTATTATCCGTGATAAC
GGTATCGGCATGAATAAAGAGGATTTAATTGATAATTTAGGTACTATTGCAAGATCTGGTACGGCAAATTTTCTTAAAAG
CCTCTCCGGTGATTCTAAAAAGGATAATATGCTAATCGGTCAATTTGGTGTTGGATTTTATTCAAGCTTTATGGTGGCCG
ATAAAGTGACTGTAACCTCAAGAAAAGCAGGCGAAGATACAGTCCATGTTTGGGAATCAGACGGGCTTGGCGAGTATATT
GTTTCAGATTCAGATAAAGAATTCACAAGAGGCACGGAAATTATTTTACATATCAAAAAAGAAGAAGATATATTCCTTGA
TCATTTCAGGTTAAAACACATCGTTAAAAGCTATTCCGATCACGTAGCAGTACCAATATATTTCTTTGATGAAGCCGGTA
ATAATGAAATCCAGCTTAATTCAGCTTCTGCATTATGGACAAGACCGAAATCAGAAATTACGGAAGAACAATATAAAGAA
TTCTACAAAAGCCTATCTTATGCCGTTGATGACCCTTGGATAACTATGCATAATAAAAACGAAGGAGCTATAGAATTTAC
TAACCTGCTTTTCATTCCTTCAAGTAAAACATTTGACTTATTTCATCCTGATCGTAAAAGGCGAGTCAAATTATATATAA
AAAGAGTGTTTATTTCTGATGAGAATATTGATTTAATTCCGTCATATTTAAGATTTTTACGAGGCGTGGTTGATTCAGAA
GACTTACCGTTAAATATTAGCCGTGAGTCATTACAGCATAATAGTGTACTTGAGAAAATCAAAAATGCTATTACAAAAAG
AGTGCTTGGTGAGCTTAGAAAAAAGAAAGAGGAATCATCTGAAGAATATAATAAGTTTTGGGCTAATTTCGGTGGGGCTT
TAAAAGAGGGTTTATGTGAAGCTACTACCGACCATGAAAAATTATTAGAGGTATGCATATTCAGAAGTGCCTTACATAAT
AAAATGATTAGCCTTGACGAATATATAGCAGGATTTAAAGAGGAACAGAATACTATATATTATTTAAGCGGTGATAACCC
AGATAAATTACTTTCAAGTCCACAAATTGAAGGATTATTAAGTAAAAATATCGATGTATTACTTTTTACCGATACAGTGG
ATGATTTTTGGGTAAATGTTAATAGCGAGTATAAAGGACATGCTATTAAGTCAGCGACAAGAAGCGATATCGATGTAGAG
CAAACTACTTCACAATCTGAAGATAAAAATACACATAGTAAAAAATCCGATGATGAATATAAATTGCTAACAGATTATTT
TAAAGAAACACTTGGGAAATTAGTAAAAGAAGTTAAGATCTCTAAAAAACTTACTTCAAGCCCTGCTTGTCTTGCCGTTA
GCGACTCTGCTATGGATATTCGTATGGAGAGATTTTTGATTGAGCAGAAACAAATAACTGCTGCATCCGCTAAAAATTTA
GAGCTCAATCCTAAAAATAAAATCATAGAAAAAATCTTTAACGACTTAAAAGCAAATAATAAAAATAATGAAGAATTGGT
TAATCTAATATTTGATCAAGCCTGTATTTTAGAGGGTGAACCGGTTGCCGATACAGGTGCATTTTCAAAGAGATTAAACG
ATATTGTACAAAAAGCTATATTATAA

Upstream 100 bases:

>100_bases
CATAATAAGATATTTTTAATGTTCTTTTTGGATTCCAGCGCACGCGGGAATGACATAGAAAGTCATATGACTAAAAAATA
ATTCATTAACTGGAATAATT

Downstream 100 bases:

>100_bases
CTTTAAACTTTTTTAATTTTAATGTAGAATAGTTGCACTCCGTTGTCATCCCGCGGCTTGATCGCTTGATCCAGTAGAAA
TACTAGTATTTTTTATTGTT

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G [H]

Number of amino acids: Translated: 621; Mature: 620

Protein sequence:

>621_residues
MTQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSHSELVASDSNFKITVKVDKDNWQIIIRDN
GIGMNKEDLIDNLGTIARSGTANFLKSLSGDSKKDNMLIGQFGVGFYSSFMVADKVTVTSRKAGEDTVHVWESDGLGEYI
VSDSDKEFTRGTEIILHIKKEEDIFLDHFRLKHIVKSYSDHVAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKE
FYKSLSYAVDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISDENIDLIPSYLRFLRGVVDSE
DLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESSEEYNKFWANFGGALKEGLCEATTDHEKLLEVCIFRSALHN
KMISLDEYIAGFKEEQNTIYYLSGDNPDKLLSSPQIEGLLSKNIDVLLFTDTVDDFWVNVNSEYKGHAIKSATRSDIDVE
QTTSQSEDKNTHSKKSDDEYKLLTDYFKETLGKLVKEVKISKKLTSSPACLAVSDSAMDIRMERFLIEQKQITAASAKNL
ELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGEPVADTGAFSKRLNDIVQKAIL

Sequences:

>Translated_621_residues
MTQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSHSELVASDSNFKITVKVDKDNWQIIIRDN
GIGMNKEDLIDNLGTIARSGTANFLKSLSGDSKKDNMLIGQFGVGFYSSFMVADKVTVTSRKAGEDTVHVWESDGLGEYI
VSDSDKEFTRGTEIILHIKKEEDIFLDHFRLKHIVKSYSDHVAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKE
FYKSLSYAVDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISDENIDLIPSYLRFLRGVVDSE
DLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESSEEYNKFWANFGGALKEGLCEATTDHEKLLEVCIFRSALHN
KMISLDEYIAGFKEEQNTIYYLSGDNPDKLLSSPQIEGLLSKNIDVLLFTDTVDDFWVNVNSEYKGHAIKSATRSDIDVE
QTTSQSEDKNTHSKKSDDEYKLLTDYFKETLGKLVKEVKISKKLTSSPACLAVSDSAMDIRMERFLIEQKQITAASAKNL
ELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGEPVADTGAFSKRLNDIVQKAIL
>Mature_620_residues
TQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSHSELVASDSNFKITVKVDKDNWQIIIRDNG
IGMNKEDLIDNLGTIARSGTANFLKSLSGDSKKDNMLIGQFGVGFYSSFMVADKVTVTSRKAGEDTVHVWESDGLGEYIV
SDSDKEFTRGTEIILHIKKEEDIFLDHFRLKHIVKSYSDHVAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKEF
YKSLSYAVDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISDENIDLIPSYLRFLRGVVDSED
LPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESSEEYNKFWANFGGALKEGLCEATTDHEKLLEVCIFRSALHNK
MISLDEYIAGFKEEQNTIYYLSGDNPDKLLSSPQIEGLLSKNIDVLLFTDTVDDFWVNVNSEYKGHAIKSATRSDIDVEQ
TTSQSEDKNTHSKKSDDEYKLLTDYFKETLGKLVKEVKISKKLTSSPACLAVSDSAMDIRMERFLIEQKQITAASAKNLE
LNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGEPVADTGAFSKRLNDIVQKAIL

Specific function: Molecular chaperone. Has ATPase activity [H]

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family [H]

Homologues:

Organism=Homo sapiens, GI4507677, Length=679, Percent_Identity=32.9896907216495, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI155722983, Length=629, Percent_Identity=33.5453100158983, Blast_Score=335, Evalue=1e-91,
Organism=Homo sapiens, GI20149594, Length=410, Percent_Identity=35.1219512195122, Blast_Score=226, Evalue=6e-59,
Organism=Homo sapiens, GI154146191, Length=410, Percent_Identity=34.1463414634146, Blast_Score=224, Evalue=1e-58,
Organism=Homo sapiens, GI153792590, Length=411, Percent_Identity=34.3065693430657, Blast_Score=223, Evalue=5e-58,
Organism=Escherichia coli, GI1786679, Length=625, Percent_Identity=42.08, Blast_Score=497, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17559162, Length=668, Percent_Identity=34.7305389221557, Blast_Score=382, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI17542208, Length=673, Percent_Identity=33.4323922734027, Blast_Score=375, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI115535205, Length=634, Percent_Identity=30.4416403785489, Blast_Score=281, Evalue=9e-76,
Organism=Caenorhabditis elegans, GI115535167, Length=421, Percent_Identity=34.4418052256532, Blast_Score=239, Evalue=3e-63,
Organism=Saccharomyces cerevisiae, GI6323840, Length=677, Percent_Identity=34.1211225997046, Blast_Score=374, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6325016, Length=410, Percent_Identity=34.390243902439, Blast_Score=238, Evalue=3e-63,
Organism=Drosophila melanogaster, GI21357739, Length=677, Percent_Identity=32.3485967503693, Blast_Score=356, Evalue=3e-98,
Organism=Drosophila melanogaster, GI24586016, Length=616, Percent_Identity=35.2272727272727, Blast_Score=329, Evalue=3e-90,
Organism=Drosophila melanogaster, GI17647529, Length=394, Percent_Identity=36.0406091370558, Blast_Score=229, Evalue=4e-60,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568 [H]

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90 [H]

EC number: NA

Molecular weight: Translated: 70808; Mature: 70677

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSHSELVASDS
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC
NFKITVKVDKDNWQIIIRDNGIGMNKEDLIDNLGTIARSGTANFLKSLSGDSKKDNMLIG
CEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEE
QFGVGFYSSFMVADKVTVTSRKAGEDTVHVWESDGLGEYIVSDSDKEFTRGTEIILHIKK
ECCHHHHHHHHHHCEEEECCCCCCCCEEEEECCCCCCCHHCCCCCCHHHCCCEEEEEEEC
EEDIFLDHFRLKHIVKSYSDHVAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKE
CCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCHHHCCCCHHHHHHHHHHH
FYKSLSYAVDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISD
HHHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHEECC
ENIDLIPSYLRFLRGVVDSEDLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESS
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEYNKFWANFGGALKEGLCEATTDHEKLLEVCIFRSALHNKMISLDEYIAGFKEEQNTIY
HHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
YLSGDNPDKLLSSPQIEGLLSKNIDVLLFTDTVDDFWVNVNSEYKGHAIKSATRSDIDVE
EEECCCHHHHHCCCCHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCHHHCCCCCCCCHH
QTTSQSEDKNTHSKKSDDEYKLLTDYFKETLGKLVKEVKISKKLTSSPACLAVSDSAMDI
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHH
RMERFLIEQKQITAASAKNLELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGE
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCC
PVADTGAFSKRLNDIVQKAIL
CCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TQEKKKFDAEVGKILNLMIHSLYSNKEIFMRELISNASDACDKLRYLSQSHSELVASDS
CCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCC
NFKITVKVDKDNWQIIIRDNGIGMNKEDLIDNLGTIARSGTANFLKSLSGDSKKDNMLIG
CEEEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEE
QFGVGFYSSFMVADKVTVTSRKAGEDTVHVWESDGLGEYIVSDSDKEFTRGTEIILHIKK
ECCHHHHHHHHHHCEEEECCCCCCCCEEEEECCCCCCCHHCCCCCCHHHCCCEEEEEEEC
EEDIFLDHFRLKHIVKSYSDHVAVPIYFFDEAGNNEIQLNSASALWTRPKSEITEEQYKE
CCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEECCHHHCCCCHHHHHHHHHHH
FYKSLSYAVDDPWITMHNKNEGAIEFTNLLFIPSSKTFDLFHPDRKRRVKLYIKRVFISD
HHHHHHHHCCCCEEEEECCCCCCEEEEEEEEECCCCEEECCCCCHHHHHHHHHHHHEECC
ENIDLIPSYLRFLRGVVDSEDLPLNISRESLQHNSVLEKIKNAITKRVLGELRKKKEESS
CCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEYNKFWANFGGALKEGLCEATTDHEKLLEVCIFRSALHNKMISLDEYIAGFKEEQNTIY
HHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEE
YLSGDNPDKLLSSPQIEGLLSKNIDVLLFTDTVDDFWVNVNSEYKGHAIKSATRSDIDVE
EEECCCHHHHHCCCCHHHHHHCCCEEEEEECCCCCEEEECCCCCCCCHHHCCCCCCCCHH
QTTSQSEDKNTHSKKSDDEYKLLTDYFKETLGKLVKEVKISKKLTSSPACLAVSDSAMDI
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHH
RMERFLIEQKQITAASAKNLELNPKNKIIEKIFNDLKANNKNNEELVNLIFDQACILEGE
HHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHEECCC
PVADTGAFSKRLNDIVQKAIL
CCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA