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The map label for this gene is map [H]

Identifier: 157826292

GI number: 157826292

Start: 1146993

End: 1147784

Strand: Direct

Name: map [H]

Synonym: A1C_06395

Alternate gene names: 157826292

Gene position: 1146993-1147784 (Clockwise)

Preceding gene: 157826279

Following gene: 157826293

Centisome position: 93.17

GC content: 36.36

Gene sequence:

>792_bases
ATGACCATAAAAATCCACACGGAACAAGATTTCATAAAGATGCGGCGAGCTGGAAAATTAGCTGCAGAGACGCTTGATTT
TATTACTGGTTACGTAAAACCGAACGTCACTACTAATAGTTTAAATAACCTTTGTCATAATTTTATTACTTCTCATAATG
CGATTCCTGCACCGTTAAATTATAAAGGCTTTCCGAAATCGATTTGTACTTCTATAAATCATGTGGTTTGTCACGGCATT
CCAAACGATAAACCATTAAAAAACGGTGATATAGTAAATATTGATGTTACAGTAATTTTAGACGGTTGGTACGGTGATAC
TAGCCGTATGTATTATGTCGGTGACGTAGCAATTAAGCCAAAGCGTCTTATTCAAATAACTTATGATGCAATGATGAAAG
GGATTGAAGTAGTTAGACCTGGTGCTAAAATCGGTGATATCGGACATGCGATTCAAAGCTATGCCGAGAAACATAATTAT
TCTGTGGTTAGAGATTATACGGGTCACGGTATCGGAAGAGTTTTTCATGACGAGCCGTCAATATTAAATTACGGCCGCAG
CGGCACAGGTCTAACGTTAGAAGAAGGGATGTTTTTCACCATTGAACCTATGATAAATGCTGGTCATTATGACACTATAT
TAAGTAAACTAGATGGATGGACGGTTACTACGCGTGATAAATCATTATCGGCTCAATTTGAACATACTATAGGTGTGACT
AAAAATGGCTTTGAAATATTTACGTTATCACCTAAAAAACTTGATTATCCTCCGTACGAAATTGTAATATAA

Upstream 100 bases:

>100_bases
ACAAGCTAATTTAATATGATTCTATAATGTCAACTTTTGAAATTTACACCTTAGAAAAAAATGTTATACTATAAACGATT
TTAAAAACTTGCAATATAAC

Downstream 100 bases:

>100_bases
AAAGGTACAAGTTGATTGTATGGTTTAGTCGTTTCGTCATTGCGAAAAAAATTACGAAGTAATGTGACGAAGCAATCCAG
TAAAAAATTCTGATTTACAG

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MTIKIHTEQDFIKMRRAGKLAAETLDFITGYVKPNVTTNSLNNLCHNFITSHNAIPAPLNYKGFPKSICTSINHVVCHGI
PNDKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIKPKRLIQITYDAMMKGIEVVRPGAKIGDIGHAIQSYAEKHNY
SVVRDYTGHGIGRVFHDEPSILNYGRSGTGLTLEEGMFFTIEPMINAGHYDTILSKLDGWTVTTRDKSLSAQFEHTIGVT
KNGFEIFTLSPKKLDYPPYEIVI

Sequences:

>Translated_263_residues
MTIKIHTEQDFIKMRRAGKLAAETLDFITGYVKPNVTTNSLNNLCHNFITSHNAIPAPLNYKGFPKSICTSINHVVCHGI
PNDKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIKPKRLIQITYDAMMKGIEVVRPGAKIGDIGHAIQSYAEKHNY
SVVRDYTGHGIGRVFHDEPSILNYGRSGTGLTLEEGMFFTIEPMINAGHYDTILSKLDGWTVTTRDKSLSAQFEHTIGVT
KNGFEIFTLSPKKLDYPPYEIVI
>Mature_262_residues
TIKIHTEQDFIKMRRAGKLAAETLDFITGYVKPNVTTNSLNNLCHNFITSHNAIPAPLNYKGFPKSICTSINHVVCHGIP
NDKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIKPKRLIQITYDAMMKGIEVVRPGAKIGDIGHAIQSYAEKHNYS
VVRDYTGHGIGRVFHDEPSILNYGRSGTGLTLEEGMFFTIEPMINAGHYDTILSKLDGWTVTTRDKSLSAQFEHTIGVTK
NGFEIFTLSPKKLDYPPYEIVI

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=253, Percent_Identity=43.0830039525692, Blast_Score=232, Evalue=3e-61,
Organism=Homo sapiens, GI40385867, Length=252, Percent_Identity=40.4761904761905, Blast_Score=201, Evalue=7e-52,
Organism=Escherichia coli, GI1786364, Length=251, Percent_Identity=54.5816733067729, Blast_Score=274, Evalue=4e-75,
Organism=Caenorhabditis elegans, GI71996291, Length=247, Percent_Identity=41.2955465587045, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6323273, Length=252, Percent_Identity=41.2698412698413, Blast_Score=213, Evalue=4e-56,
Organism=Drosophila melanogaster, GI21355531, Length=246, Percent_Identity=45.5284552845528, Blast_Score=225, Evalue=2e-59,
Organism=Drosophila melanogaster, GI24583427, Length=245, Percent_Identity=40.8163265306122, Blast_Score=196, Evalue=9e-51,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29367; Mature: 29236

Theoretical pI: Translated: 7.73; Mature: 7.73

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKIHTEQDFIKMRRAGKLAAETLDFITGYVKPNVTTNSLNNLCHNFITSHNAIPAPLN
CEEEEECCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
YKGFPKSICTSINHVVCHGIPNDKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIKP
CCCCCHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEEEECC
KRLIQITYDAMMKGIEVVRPGAKIGDIGHAIQSYAEKHNYSVVRDYTGHGIGRVFHDEPS
HHEEEEEHHHHHCCHHEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCC
ILNYGRSGTGLTLEEGMFFTIEPMINAGHYDTILSKLDGWTVTTRDKSLSAQFEHTIGVT
HHHCCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCCEEHEEECCC
KNGFEIFTLSPKKLDYPPYEIVI
CCCEEEEEECCCCCCCCCEEEEC
>Mature Secondary Structure 
TIKIHTEQDFIKMRRAGKLAAETLDFITGYVKPNVTTNSLNNLCHNFITSHNAIPAPLN
EEEEECCHHHHHHHHHCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
YKGFPKSICTSINHVVCHGIPNDKPLKNGDIVNIDVTVILDGWYGDTSRMYYVGDVAIKP
CCCCCHHHHHCCCEEEEECCCCCCCCCCCCEEEEEEEEEEECCCCCCCCEEEEEEEEECC
KRLIQITYDAMMKGIEVVRPGAKIGDIGHAIQSYAEKHNYSVVRDYTGHGIGRVFHDEPS
HHEEEEEHHHHHCCHHEECCCCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCC
ILNYGRSGTGLTLEEGMFFTIEPMINAGHYDTILSKLDGWTVTTRDKSLSAQFEHTIGVT
HHHCCCCCCCEEECCCEEEEEECCCCCCHHHHHHHHCCCCEEEECCCCCCCEEHEEECCC
KNGFEIFTLSPKKLDYPPYEIVI
CCCEEEEEECCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]