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The map label for this gene is tagO [H]

Identifier: 157826293

GI number: 157826293

Start: 1148887

End: 1149870

Strand: Direct

Name: tagO [H]

Synonym: A1C_06410

Alternate gene names: 157826293

Gene position: 1148887-1149870 (Clockwise)

Preceding gene: 157826292

Following gene: 157826294

Centisome position: 93.33

GC content: 30.08

Gene sequence:

>984_bases
ATGAATATAAATAGCTATAGCACATTATTTATTTTTTCTTTTATAGCCACCGCTATATTAACATATATATTAACTAAATA
TCTTACTGCAATCGGTTTAGTTGATGTACCTAGTAGTCGTCGCTCTCATGATAAGATAACACCGCGCGGCGGCGGTCTCG
CTATTGTCATTGTCGTAATGATTGCTTTGAGCGGGTTTGAATATATAATGAGCAATAACCTTGCTAATTCAATAAAAATA
TTACCGTTATTATTGATCATTGCATCGATTTCCTTTTTAGATGACTTAAAAGCTGTACCTATTCTAATTCGTTTAATAGT
CCACTTAATTTGTGCAGCTTTTGCTATTTTTCTTTTTTCGCAGCTAAACTCTGTACATATACTAATATATTCTATTTTAG
TTATAGCTTTAAGCGGTTTTATTAATATATATAATTTTATGGATGGTATAGACGGTATGAGTTGTGTCGAATCTATCCAT
CTATCTAGCACTATGCTTATATTATGTTTTTTACAATTTTCGATTATTGATAACCCATATTTTATAGCTAGTGTAAATGT
TATTATTCTTGGTTGTTCTTGTGGTTTTTTAATATTTAATTGGCATCCGGCAAAAATATTTTTAGGCGACGTAGGAAGTA
TTAGCCTTGGATTCTTAACTGGTCTTTGTTTGGTCCTGCTTGCTCTTACAAATACTAATTTATTTATAGCTTGTGTTATT
GCTAGTTTATATTACATTACCGATGCCGTACTAACCATATTAATTCGACTACTCAATAAAGAAAAAATTTGGCAGCCTCA
TCTAAAGCATTTTTTTCAAAAAGCAGTAAAAAAAGGTAAGTCTCATAAACAAGTAGTATCGATTATAGCAGTTTGTAATA
TATTTTTAATGATCATATCAGTTACATCTTTACATTTTCCTGTAATATCTATAATACTTGCTGTAGCCGTCATAACTTTA
ACAGTGCAAAGTTTATTAAAATGA

Upstream 100 bases:

>100_bases
AAGCTAGTAGAGAAATGCCAAACCGTAAAAATATTATGGTACATGATCACGTCATTATAAGTAATAACAAATATTATAGT
TTTAAATCTAATATGTTACT

Downstream 100 bases:

>100_bases
AGCTAATTAAAGAAGATATTGATAAAATAGTTAGACGTATATTCGCCAAACAACATCCATTGCTTCCTGCAATCATGATT
AACTGGAATAAAATAGTCGG

Product: undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase

Products: Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine; UMP [C]

Alternate protein names: UDP-GlcNAc:undecaprenyl-phosphate GlcNAc-1-phosphate transferase; Undecaprenyl-Phosphate GlcNAc-1-phosphate transferase [H]

Number of amino acids: Translated: 327; Mature: 327

Protein sequence:

>327_residues
MNINSYSTLFIFSFIATAILTYILTKYLTAIGLVDVPSSRRSHDKITPRGGGLAIVIVVMIALSGFEYIMSNNLANSIKI
LPLLLIIASISFLDDLKAVPILIRLIVHLICAAFAIFLFSQLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIH
LSSTMLILCFLQFSIIDNPYFIASVNVIILGCSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLVLLALTNTNLFIACVI
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVKKGKSHKQVVSIIAVCNIFLMIISVTSLHFPVISIILAVAVITL
TVQSLLK

Sequences:

>Translated_327_residues
MNINSYSTLFIFSFIATAILTYILTKYLTAIGLVDVPSSRRSHDKITPRGGGLAIVIVVMIALSGFEYIMSNNLANSIKI
LPLLLIIASISFLDDLKAVPILIRLIVHLICAAFAIFLFSQLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIH
LSSTMLILCFLQFSIIDNPYFIASVNVIILGCSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLVLLALTNTNLFIACVI
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVKKGKSHKQVVSIIAVCNIFLMIISVTSLHFPVISIILAVAVITL
TVQSLLK
>Mature_327_residues
MNINSYSTLFIFSFIATAILTYILTKYLTAIGLVDVPSSRRSHDKITPRGGGLAIVIVVMIALSGFEYIMSNNLANSIKI
LPLLLIIASISFLDDLKAVPILIRLIVHLICAAFAIFLFSQLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIH
LSSTMLILCFLQFSIIDNPYFIASVNVIILGCSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLVLLALTNTNLFIACVI
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVKKGKSHKQVVSIIAVCNIFLMIISVTSLHFPVISIILAVAVITL
TVQSLLK

Specific function: Catalyzes the formation of undecaprenyl-PP-N- acetylglucosamine. Involved in the synthesis of anionic cell-wall polymers as it mediates the initiation of the linkage unit formation that appears to be common to the two types of teichoic acids attached to t

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4 [H]

EC number: 2.7.8.13 [C]

Molecular weight: Translated: 35987; Mature: 35987

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINSYSTLFIFSFIATAILTYILTKYLTAIGLVDVPSSRRSHDKITPRGGGLAIVIVVM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IALSGFEYIMSNNLANSIKILPLLLIIASISFLDDLKAVPILIRLIVHLICAAFAIFLFS
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIHLSSTMLILCFLQFSIIDNPY
HHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
FIASVNVIILGCSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLVLLALTNTNLFIACVI
EEEEHEEEEEECCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVKKGKSHKQVVSIIAVCNIFLMIIS
HHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VTSLHFPVISIILAVAVITLTVQSLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MNINSYSTLFIFSFIATAILTYILTKYLTAIGLVDVPSSRRSHDKITPRGGGLAIVIVVM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IALSGFEYIMSNNLANSIKILPLLLIIASISFLDDLKAVPILIRLIVHLICAAFAIFLFS
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLNSVHILIYSILVIALSGFINIYNFMDGIDGMSCVESIHLSSTMLILCFLQFSIIDNPY
HHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
FIASVNVIILGCSCGFLIFNWHPAKIFLGDVGSISLGFLTGLCLVLLALTNTNLFIACVI
EEEEHEEEEEECCCCEEEEECCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHH
ASLYYITDAVLTILIRLLNKEKIWQPHLKHFFQKAVKKGKSHKQVVSIIAVCNIFLMIIS
HHHHHHHHHHHHHHHHHHCHHCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHH
VTSLHFPVISIILAVAVITLTVQSLLK
HHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Undecaprenyl phosphate; UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine [C]

Specific reaction: Undecaprenyl phosphate + UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine --> Undecaprenyl-diphospho-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP [C]

General reaction: Substituted phospho group transfer [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12101296; 9384377 [H]