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The map label for this gene is pld [H]

Identifier: 157826280

GI number: 157826280

Start: 1134110

End: 1134712

Strand: Reverse

Name: pld [H]

Synonym: A1C_06325

Alternate gene names: 157826280

Gene position: 1134712-1134110 (Counterclockwise)

Preceding gene: 157826281

Following gene: 157826278

Centisome position: 92.17

GC content: 33.0

Gene sequence:

>603_bases
ATGAAGAGAAAAAATAATAAATTTATAGAAATATCTATTGCCTTTATCTTGGGCGTTGCTTTAGGTATTGATGGACAGAA
TCCTGATTATTTTACTAATCTAATAAATCAAAAATCATTCGCTTTATCTGCTCCACAAATAAAGCATTACAATATTTCAG
AGCCTGCAAGAAGTAAAGTTAGTACGTGTTTTACTCCACCTGCCGGTTGTACTAAGTTTATAGCCAATCAGATAGATAAA
GCTGAAGAATCTATTTATATGCAGGCATACGGTATGAGCGATGCGTTAATTACTACTGCACTTATTAATGCACAGATGCG
AGGAGTAAAAGTTAGAATATTGCTTGATCGTAGTAATTTAAAGCAGAAATTTTCTAAATTACACGAATTACAACAAGCAA
AAATTGATGTAGGTATAGATAAAGTACCGGGAATTGCTCATAATAAAGTTATAATTATTGATAAAAAGCAAGTAATAACC
GGTTCGTTTAATTTCACGGCTGCTGCCGACAAACGTAATGCCGAAAATGTGATTGCTATAGAAGATCAGGAGGTAGCAGA
GTCTTATTTACAAAATTGGTTACACAGAAAGGCTAGTAATTGA

Upstream 100 bases:

>100_bases
GGAAGTAGGTGTTATTACTTCATTGTCATTCCCGCCTACGCGTGAATGACAATGTGTGTTTCTTGATCCATACACACAAC
GCCTAAAATATAAATAAGTC

Downstream 100 bases:

>100_bases
TGCAAAGTGTTGCTGTATGATTCTCACGTCATGCCTATAAAAGCAGGAATCTAAAAAAAGTATAAAAGCAGCAAATTTTT
GAAATTAAAAACCCGATTTA

Product: phospholipase D (PLD) superfamily protein

Products: NA

Alternate protein names: PLD; Choline phosphatase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MKRKNNKFIEISIAFILGVALGIDGQNPDYFTNLINQKSFALSAPQIKHYNISEPARSKVSTCFTPPAGCTKFIANQIDK
AEESIYMQAYGMSDALITTALINAQMRGVKVRILLDRSNLKQKFSKLHELQQAKIDVGIDKVPGIAHNKVIIIDKKQVIT
GSFNFTAAADKRNAENVIAIEDQEVAESYLQNWLHRKASN

Sequences:

>Translated_200_residues
MKRKNNKFIEISIAFILGVALGIDGQNPDYFTNLINQKSFALSAPQIKHYNISEPARSKVSTCFTPPAGCTKFIANQIDK
AEESIYMQAYGMSDALITTALINAQMRGVKVRILLDRSNLKQKFSKLHELQQAKIDVGIDKVPGIAHNKVIIIDKKQVIT
GSFNFTAAADKRNAENVIAIEDQEVAESYLQNWLHRKASN
>Mature_200_residues
MKRKNNKFIEISIAFILGVALGIDGQNPDYFTNLINQKSFALSAPQIKHYNISEPARSKVSTCFTPPAGCTKFIANQIDK
AEESIYMQAYGMSDALITTALINAQMRGVKVRILLDRSNLKQKFSKLHELQQAKIDVGIDKVPGIAHNKVIIIDKKQVIT
GSFNFTAAADKRNAENVIAIEDQEVAESYLQNWLHRKASN

Specific function: Could be a virulence factor [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PLD phosphodiesterase domain [H]

Homologues:

Organism=Homo sapiens, GI270265812, Length=103, Percent_Identity=34.9514563106796, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: NA

EC number: =3.1.4.4 [H]

Molecular weight: Translated: 22310; Mature: 22310

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKNNKFIEISIAFILGVALGIDGQNPDYFTNLINQKSFALSAPQIKHYNISEPARSKV
CCCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHCCCHHEECCCCEECCCCCCHHHHHH
STCFTPPAGCTKFIANQIDKAEESIYMQAYGMSDALITTALINAQMRGVKVRILLDRSNL
HHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCEEEEEEECCHHH
KQKFSKLHELQQAKIDVGIDKVPGIAHNKVIIIDKKQVITGSFNFTAAADKRNAENVIAI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEECCCCEEEECCCCCCCCEEEE
EDQEVAESYLQNWLHRKASN
CCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKRKNNKFIEISIAFILGVALGIDGQNPDYFTNLINQKSFALSAPQIKHYNISEPARSKV
CCCCCCCEEEEEHHHHHHHHHCCCCCCCHHHHHHHCCCHHEECCCCEECCCCCCHHHHHH
STCFTPPAGCTKFIANQIDKAEESIYMQAYGMSDALITTALINAQMRGVKVRILLDRSNL
HHCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHHHHHCCEEEEEEECCHHH
KQKFSKLHELQQAKIDVGIDKVPGIAHNKVIIIDKKQVITGSFNFTAAADKRNAENVIAI
HHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCEEEECCCCEEEECCCCCCCCEEEE
EDQEVAESYLQNWLHRKASN
CCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]