| Definition | Rickettsia akari str. Hartford, complete genome. |
|---|---|
| Accession | NC_009881 |
| Length | 1,231,060 |
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The map label for this gene is valS [H]
Identifier: 157826186
GI number: 157826186
Start: 1030648
End: 1031613
Strand: Direct
Name: valS [H]
Synonym: A1C_05815
Alternate gene names: 157826186
Gene position: 1030648-1031613 (Clockwise)
Preceding gene: 157826182
Following gene: 157826187
Centisome position: 83.72
GC content: 31.16
Gene sequence:
>966_bases ATGGATGACAAGCATAAGTTCCTAATCATCCCATCTATCTTCAACTCACCGGAAATATTTTTTCTAGCTCGTGGCAAAAA TTTTATTGAAAATTTGAGAAACTACGGTGAAGTTTATTTAATAGATTGGCTAGAGATTGAGGAACCTAAATATTTACTAG ACGACTATGTGCATAAAATCATTGAAGTAATAGATAGTTTGAAAATTAAAGACATTAATTGCATAGGTCATTGTATCGGC GGTAACCTTGCGATAGCTACAAATGTACTTATACCTAAATTTATAAAAACTCTGACTTTACTTACCTGCCCGTGGGATTT TTCTCATTTTTTTTATATAAGAATGTTGCATCGATGTTTAAAACTAGATAGTGGCATAGAAAATTTACCGACAATTCCTA AGATTCATATTCAAATTTTATTTTTTCTGTTATTTCCTAACTATTTCAATGCTAAATTAAAAAAATTCTGCTCTATCACT TCTGATCAGGAGCAAGAATTAGCATTTAGAATAGAACATTGGCTTACGTCAGGAAACAATATATCTAAAGGTGTGTATAA TCAAATCATACAAAATATATTGGATAAAAATATGTTTATAAATCTTAAATGGCAAATCGATAATAGATCTCTTCAGAAAT TCGCTTATAGAAAGGAATTTGGAGGAGACACGGAACGCAGCACCGCATCGTATATAAACATACGTGAGGATGCGAGTACC GGATCGACGTACAAATTACCTCTAGAAGTAGAGTTGCCGAAGAGGTCTAATTTTATTATTGATCCGAGTTTAATCGATTG CCCTGTATATATAGTAGCAGCGGAAGATGATCAAATAGTGCCTAAATCTTCCATTTTATCTTTGCAAAAATTATTAAAAA ACTCTAAACTTATAGAAGTAAAAGGCGGACATATTAGCTATTTGATAAATAGTAAATTAGATAAATTATTTAAGGAGTAT ACTTAG
Upstream 100 bases:
>100_bases ATCATCCTCAATGCCATCCTTGTCATTCCCACGAAAGCGTGAATCTAGAGATAATCACAAGATGTGTTCCCGCTTTCGCG GGAATGACATAAACAGAGAC
Downstream 100 bases:
>100_bases ATAGAACTTCAAAAATTGGCGTTGTCATTCTATGAGCTCAGGTGCTCACGTATTACTATACGCTCCGATCCAAGGACTCT GCATGCCTAGTTCTTTTTGA
Product: Poly-beta-hydroxybutyrate polymerase
Products: NA
Alternate protein names: Valine--tRNA ligase; ValRS [H]
Number of amino acids: Translated: 321; Mature: 321
Protein sequence:
>321_residues MDDKHKFLIIPSIFNSPEIFFLARGKNFIENLRNYGEVYLIDWLEIEEPKYLLDDYVHKIIEVIDSLKIKDINCIGHCIG GNLAIATNVLIPKFIKTLTLLTCPWDFSHFFYIRMLHRCLKLDSGIENLPTIPKIHIQILFFLLFPNYFNAKLKKFCSIT SDQEQELAFRIEHWLTSGNNISKGVYNQIIQNILDKNMFINLKWQIDNRSLQKFAYRKEFGGDTERSTASYINIREDAST GSTYKLPLEVELPKRSNFIIDPSLIDCPVYIVAAEDDQIVPKSSILSLQKLLKNSKLIEVKGGHISYLINSKLDKLFKEY T
Sequences:
>Translated_321_residues MDDKHKFLIIPSIFNSPEIFFLARGKNFIENLRNYGEVYLIDWLEIEEPKYLLDDYVHKIIEVIDSLKIKDINCIGHCIG GNLAIATNVLIPKFIKTLTLLTCPWDFSHFFYIRMLHRCLKLDSGIENLPTIPKIHIQILFFLLFPNYFNAKLKKFCSIT SDQEQELAFRIEHWLTSGNNISKGVYNQIIQNILDKNMFINLKWQIDNRSLQKFAYRKEFGGDTERSTASYINIREDAST GSTYKLPLEVELPKRSNFIIDPSLIDCPVYIVAAEDDQIVPKSSILSLQKLLKNSKLIEVKGGHISYLINSKLDKLFKEY T >Mature_321_residues MDDKHKFLIIPSIFNSPEIFFLARGKNFIENLRNYGEVYLIDWLEIEEPKYLLDDYVHKIIEVIDSLKIKDINCIGHCIG GNLAIATNVLIPKFIKTLTLLTCPWDFSHFFYIRMLHRCLKLDSGIENLPTIPKIHIQILFFLLFPNYFNAKLKKFCSIT SDQEQELAFRIEHWLTSGNNISKGVYNQIIQNILDKNMFINLKWQIDNRSLQKFAYRKEFGGDTERSTASYINIREDAST GSTYKLPLEVELPKRSNFIIDPSLIDCPVYIVAAEDDQIVPKSSILSLQKLLKNSKLIEVKGGHISYLINSKLDKLFKEY T
Specific function: Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val)
COG id: COG3243
COG function: function code I; Poly(3-hydroxyalkanoate) synthetase
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: NA
Operon status: Not Known
Operon components: None
Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily [H]
Homologues:
None
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR001412 - InterPro: IPR002300 - InterPro: IPR005728 - InterPro: IPR014729 - InterPro: IPR009080 - InterPro: IPR013155 - InterPro: IPR009008 - InterPro: IPR002303 - InterPro: IPR022874 [H]
Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1 [H]
EC number: =6.1.1.9 [H]
Molecular weight: Translated: 37294; Mature: 37294
Theoretical pI: Translated: 7.85; Mature: 7.85
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.9 %Cys (Translated Protein) 0.9 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 1.9 %Cys (Mature Protein) 0.9 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDDKHKFLIIPSIFNSPEIFFLARGKNFIENLRNYGEVYLIDWLEIEEPKYLLDDYVHKI CCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHH IEVIDSLKIKDINCIGHCIGGNLAIATNVLIPKFIKTLTLLTCPWDFSHFFYIRMLHRCL HHHHHCCCCEEEHHHHHHCCCCEEEHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHH KLDSGIENLPTIPKIHIQILFFLLFPNYFNAKLKKFCSITSDQEQELAFRIEHWLTSGNN HHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC ISKGVYNQIIQNILDKNMFINLKWQIDNRSLQKFAYRKEFGGDTERSTASYINIREDAST CCHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCCCCCCHHHEEEEECCCCC GSTYKLPLEVELPKRSNFIIDPSLIDCPVYIVAAEDDQIVPKSSILSLQKLLKNSKLIEV CCEEEEEEEEECCCCCCEEECCCEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEE KGGHISYLINSKLDKLFKEYT ECCEEEEEHHHHHHHHHHHCC >Mature Secondary Structure MDDKHKFLIIPSIFNSPEIFFLARGKNFIENLRNYGEVYLIDWLEIEEPKYLLDDYVHKI CCCCCEEEEEECCCCCCCEEEEECCHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHHH IEVIDSLKIKDINCIGHCIGGNLAIATNVLIPKFIKTLTLLTCPWDFSHFFYIRMLHRCL HHHHHCCCCEEEHHHHHHCCCCEEEHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHH KLDSGIENLPTIPKIHIQILFFLLFPNYFNAKLKKFCSITSDQEQELAFRIEHWLTSGNN HHCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCC ISKGVYNQIIQNILDKNMFINLKWQIDNRSLQKFAYRKEFGGDTERSTASYINIREDAST CCHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHHCCCCCCCCHHHEEEEECCCCC GSTYKLPLEVELPKRSNFIIDPSLIDCPVYIVAAEDDQIVPKSSILSLQKLLKNSKLIEV CCEEEEEEEEECCCCCCEEECCCEECCCEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEE KGGHISYLINSKLDKLFKEYT ECCEEEEEHHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA