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The map label for this gene is murA [H]

Identifier: 157825959

GI number: 157825959

Start: 810559

End: 811818

Strand: Reverse

Name: murA [H]

Synonym: A1C_04505

Alternate gene names: 157825959

Gene position: 811818-810559 (Counterclockwise)

Preceding gene: 157825960

Following gene: 157825958

Centisome position: 65.94

GC content: 37.06

Gene sequence:

>1260_bases
ATGCAAAAATTAATTATTCATGGCGGTAAACCTCTTAAAGGTAATATTAATATTAGTGGTGCTAAAAATGCCGTGTTACC
TATTATGGCAGCGTCTATTCTTACCGATAAACTGCATATTACTAATGTTCCAAAATTAACGGATGTTAGTACTATGAAAG
ATTTGCTCCGCAGTCACGGGGCATGTATCGAAATAATAGAACACACGGATGAATTTGAGCTTATAATTAATACCGGTAAT
ATAAATAACTTTACTGCAGATTATGAAATAGTTCGTAAAATGAGAGCATCTATTTGGGTGCTCGGTCCTTTGCTTACTAA
ATACGGTAAAGCAAAAGTGTCGCTCCCGGGTGGTTGTGCTATTGGAGCAAGACAAGTAGATTTGCATATTGCCGTATTAA
AAGCTATGGGAGCTACGATTGAAATAGAAGACGGTTATATTAACGCTTCAAGTAAAGGACGCTTAAAAGGTACTCATTTT
GTTTTTGATAAAGTTTCCGTCGGTGCTACGATTAATGCAATACTTGCAGCTGTTTTAGCAGAGGGGGAGACTGTGCTTTT
TAATTGCGCCCTGGAGCCGGAGATAGTTGATTTATGTAATTGCCTTATCAAAATGGGAGCCGATATTGCAGGCGTCGGTA
CTAGTGAAATAACGATAAAAGGTAAAGATTCTTTAAATAAAATGAGCTATAAAGTACTTTCTGATCGTATTGAAGCAGGT
ACTTATATGTTTGCGGCAGCTATTACTAAAGGTGATGTAAAAATTTGTGGGATTGATTACCATATTATAGAAAATATAGC
TTTAAAACTTATTGAAACCGGTATAAAAGTTGCGCCGATCAATAACGGAGTTCAAGTAACTTATGAAGGGACGTTAAATT
CAGTTGATTTAGAAACTAATCCCTATCCTGGCTTTGCTACTGATTTGCAAGCACAATTTATGAGCCTTATGACGCTGAGT
AGCGGTGTTTCAATGATTACCGAGAATATTTTTGAAAATCGTTTCATGCATGTCCCTGAATTATGTAGAATGGGAGCAGA
TATAGTGGTACGAGGTAATAAGGCGGTCGTTCGGGGTGTAGAAATGTTAAAAGGAGCAGAAGTTATGGCAAGCGACCTTA
GAGCTTCGGTATCGCTAATACTCGCAGGGCTCAGTACTAATAGCAAAACCGTATTACACAGAATATATCACTTGGATCGT
GGCTTTCAAGATTTAGAAAAAAAATTAAGTAATTGTGGTGCGGATATAAAAAGGGTATAA

Upstream 100 bases:

>100_bases
TTCAAATATGTAATTTTTAAATATTAAGGTTTTTTCTTGATTCCCGCCTGCGCTGGAATGAATGACATTAAGAACGGTAA
GCATGACATAACCAAAACTT

Downstream 100 bases:

>100_bases
CATACTCGATGAACTTCAAAAATTGGCTAATTCGTTCAGAGATGCGGTACTCACGTATTAACTATATGTTGCGTTCCTCG
CCTTGTGAACTCCTTACTCT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MQKLIIHGGKPLKGNINISGAKNAVLPIMAASILTDKLHITNVPKLTDVSTMKDLLRSHGACIEIIEHTDEFELIINTGN
INNFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCAIGARQVDLHIAVLKAMGATIEIEDGYINASSKGRLKGTHF
VFDKVSVGATINAILAAVLAEGETVLFNCALEPEIVDLCNCLIKMGADIAGVGTSEITIKGKDSLNKMSYKVLSDRIEAG
TYMFAAAITKGDVKICGIDYHIIENIALKLIETGIKVAPINNGVQVTYEGTLNSVDLETNPYPGFATDLQAQFMSLMTLS
SGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGVEMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDR
GFQDLEKKLSNCGADIKRV

Sequences:

>Translated_419_residues
MQKLIIHGGKPLKGNINISGAKNAVLPIMAASILTDKLHITNVPKLTDVSTMKDLLRSHGACIEIIEHTDEFELIINTGN
INNFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCAIGARQVDLHIAVLKAMGATIEIEDGYINASSKGRLKGTHF
VFDKVSVGATINAILAAVLAEGETVLFNCALEPEIVDLCNCLIKMGADIAGVGTSEITIKGKDSLNKMSYKVLSDRIEAG
TYMFAAAITKGDVKICGIDYHIIENIALKLIETGIKVAPINNGVQVTYEGTLNSVDLETNPYPGFATDLQAQFMSLMTLS
SGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGVEMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDR
GFQDLEKKLSNCGADIKRV
>Mature_419_residues
MQKLIIHGGKPLKGNINISGAKNAVLPIMAASILTDKLHITNVPKLTDVSTMKDLLRSHGACIEIIEHTDEFELIINTGN
INNFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCAIGARQVDLHIAVLKAMGATIEIEDGYINASSKGRLKGTHF
VFDKVSVGATINAILAAVLAEGETVLFNCALEPEIVDLCNCLIKMGADIAGVGTSEITIKGKDSLNKMSYKVLSDRIEAG
TYMFAAAITKGDVKICGIDYHIIENIALKLIETGIKVAPINNGVQVTYEGTLNSVDLETNPYPGFATDLQAQFMSLMTLS
SGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGVEMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDR
GFQDLEKKLSNCGADIKRV

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=421, Percent_Identity=48.2185273159145, Blast_Score=392, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45218; Mature: 45218

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLIIHGGKPLKGNINISGAKNAVLPIMAASILTDKLHITNVPKLTDVSTMKDLLRSHG
CCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHCC
ACIEIIEHTDEFELIINTGNINNFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCA
CEEEEECCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
IGARQVDLHIAVLKAMGATIEIEDGYINASSKGRLKGTHFVFDKVSVGATINAILAAVLA
CCCEEEHHHHEEHHHHCCEEEEECCEEECCCCCCCCCEEEEEECEECCHHHHHHHHHHHC
EGETVLFNCALEPEIVDLCNCLIKMGADIAGVGTSEITIKGKDSLNKMSYKVLSDRIEAG
CCCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCCEEEEECCCCHHHHHHHHHHHHHHCC
TYMFAAAITKGDVKICGIDYHIIENIALKLIETGIKVAPINNGVQVTYEGTLNSVDLETN
CEEEEEEEECCCEEEEECHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCEEECCCC
PYPGFATDLQAQFMSLMTLSSGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGV
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCEEEECCHHHHHHH
EMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDRGFQDLEKKLSNCGADIKRV
HHHCCHHHHHHHHHHHEEHEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQKLIIHGGKPLKGNINISGAKNAVLPIMAASILTDKLHITNVPKLTDVSTMKDLLRSHG
CCEEEEECCCCCCCCEEECCCCCHHHHHHHHHHHHCCEEECCCCCCCCHHHHHHHHHHCC
ACIEIIEHTDEFELIINTGNINNFTADYEIVRKMRASIWVLGPLLTKYGKAKVSLPGGCA
CEEEEECCCCCEEEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCC
IGARQVDLHIAVLKAMGATIEIEDGYINASSKGRLKGTHFVFDKVSVGATINAILAAVLA
CCCEEEHHHHEEHHHHCCEEEEECCEEECCCCCCCCCEEEEEECEECCHHHHHHHHHHHC
EGETVLFNCALEPEIVDLCNCLIKMGADIAGVGTSEITIKGKDSLNKMSYKVLSDRIEAG
CCCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCCEEEEECCCCHHHHHHHHHHHHHHCC
TYMFAAAITKGDVKICGIDYHIIENIALKLIETGIKVAPINNGVQVTYEGTLNSVDLETN
CEEEEEEEECCCEEEEECHHHHHHHHHHHHHHCCCEEEECCCCEEEEECCCCCEEECCCC
PYPGFATDLQAQFMSLMTLSSGVSMITENIFENRFMHVPELCRMGADIVVRGNKAVVRGV
CCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCEEEECCHHHHHHH
EMLKGAEVMASDLRASVSLILAGLSTNSKTVLHRIYHLDRGFQDLEKKLSNCGADIKRV
HHHCCHHHHHHHHHHHEEHEEEECCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA