| Definition | Rickettsia akari str. Hartford, complete genome. |
|---|---|
| Accession | NC_009881 |
| Length | 1,231,060 |
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The map label for this gene is glmU [H]
Identifier: 157825897
GI number: 157825897
Start: 752952
End: 753698
Strand: Direct
Name: glmU [H]
Synonym: A1C_04180
Alternate gene names: 157825897
Gene position: 752952-753698 (Clockwise)
Preceding gene: 157825896
Following gene: 157825898
Centisome position: 61.16
GC content: 29.99
Gene sequence:
>747_bases ATGACTTATAGCGATGCAAATTATCAAATAATTATTTTAGCAGCCGGTAAAGGGACTAGAATGGAGTCCGATTTACCAAA AGTAATGCATAAAGTCGGCGGAGTTCCAATGCTTGAAACGGTATTAAAGAATTCGCTTAACGTCACAAATGATGTAATTA TAGTTTATTCAGAAGCACTTAAAAAACATTTAATGCCCTATGAAAATATGTGTCGTTTTGTACTGCAAGAAGAACCTAAA GGCACAGCTCATGCTACTTATGCAGTAATAGATTTAATTGATAAAAATAAAACAATATTAGTTTTATATGGTGATCATCC TCTTATTACTCCAAAACTTATGCATGAATTAATAGATTATTTAGGCCTTACTAATTCTGCATTAGTTACTTTAAGCTTTG AGAGAGCAAATCCGGCTCAATATGGAAGAATAGCTACTGATAGACATGGTGAATTTTTAGAGATAATTGAACATAAAAAC GCAAGCGAAGAAGAAAAAAACATCACACTTTGTAATTCAGGTATTATGGCTTTCAGTAGCGGAATTTTAAATAAGTACTT ACCTTTATTTGCTACTAATACTAACGGTAATAAGGAAATTTATTTAACTGAAATAGTAAAAATATGTAAAAATTACGGTG AAAAGGTTTCATATTTATTATCTACTGATAATGATTTAATTGTTGGTGTTAATACTCAACATGAGCTAGAAGAAGCTAAT AATATTTTTTCTAAGAATAAGTCTTAG
Upstream 100 bases:
>100_bases TAAAGCTTGTAGAAGCTTTAGAAGAAAGCGACGATGTACAAAGAGTTTTCAGTAATTATGAATTCTCCGATGATGTTTAC GAAATAATACAAGGAGAAGA
Downstream 100 bases:
>100_bases CGTTGCGGTATATGGATCGTTTTTATCGTCACTGCGAGGAAAAACTGTAAGTTTTGACTAAACAATCTCAGGATTTGTTA TTATTGCCTGAGATTGCAGC
Product: UDP-N-acetylglucosamine pyrophosphorylase
Products: NA
Alternate protein names: UDP-N-acetylglucosamine pyrophosphorylase; N-acetylglucosamine-1-phosphate uridyltransferase; Glucosamine-1-phosphate N-acetyltransferase [H]
Number of amino acids: Translated: 248; Mature: 247
Protein sequence:
>248_residues MTYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEALKKHLMPYENMCRFVLQEEPK GTAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDYLGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKN ASEEEKNITLCNSGIMAFSSGILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEAN NIFSKNKS
Sequences:
>Translated_248_residues MTYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEALKKHLMPYENMCRFVLQEEPK GTAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDYLGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKN ASEEEKNITLCNSGIMAFSSGILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEAN NIFSKNKS >Mature_247_residues TYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEALKKHLMPYENMCRFVLQEEPKG TAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDYLGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKNA SEEEKNITLCNSGIMAFSSGILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEANN IFSKNKS
Specific function: Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-GlcNAc. Responsible for the acetylation of Glc-N-1-P to give GlcNAc-1-P and for the uridyl transfer from UTP to GlcNAc-1-P which produces UDP-GlcNAc [H]
COG id: COG1207
COG function: function code M; N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transferase hexapeptide repeat family [H]
Homologues:
Organism=Escherichia coli, GI1790168, Length=243, Percent_Identity=32.5102880658436, Blast_Score=122, Evalue=3e-29,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR005882 - InterPro: IPR005835 - InterPro: IPR011004 [H]
Pfam domain/function: PF00483 NTP_transferase [H]
EC number: =2.7.7.23; =2.3.1.157 [H]
Molecular weight: Translated: 27785; Mature: 27654
Theoretical pI: Translated: 6.09; Mature: 6.09
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 3.2 %Met (Translated Protein) 4.4 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 4.0 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MTYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEAL CCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEHHHH KKHLMPYENMCRFVLQEEPKGTAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDY HHHCCCHHHHHHHHHHCCCCCCHHHHEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHH LGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKNASEEEKNITLCNSGIMAFSS HCCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHH GILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEAN HHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHCHHEEEEEECCCCEEEEECCHHHHHHHH NIFSKNKS HHHCCCCC >Mature Secondary Structure TYSDANYQIIILAAGKGTRMESDLPKVMHKVGGVPMLETVLKNSLNVTNDVIIVYSEAL CCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCEEEEEHHHH KKHLMPYENMCRFVLQEEPKGTAHATYAVIDLIDKNKTILVLYGDHPLITPKLMHELIDY HHHCCCHHHHHHHHHHCCCCCCHHHHEEEEEEECCCCEEEEEECCCCCCCHHHHHHHHHH LGLTNSALVTLSFERANPAQYGRIATDRHGEFLEIIEHKNASEEEKNITLCNSGIMAFSS HCCCCCEEEEEEECCCCCHHHCCCCCCCCCHHHHHHHCCCCCCCCCCEEEECCCHHHHHH GILNKYLPLFATNTNGNKEIYLTEIVKICKNYGEKVSYLLSTDNDLIVGVNTQHELEEAN HHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHCHHEEEEEECCCCEEEEECCHHHHHHHH NIFSKNKS HHHCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: NA