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The map label for this gene is scrA [H]

Identifier: 157372438

GI number: 157372438

Start: 4662717

End: 4664087

Strand: Direct

Name: scrA [H]

Synonym: Spro_4205

Alternate gene names: 157372438

Gene position: 4662717-4664087 (Clockwise)

Preceding gene: 157372437

Following gene: 157372439

Centisome position: 85.57

GC content: 58.86

Gene sequence:

>1371_bases
ATGGACATTACCGCAACCGCTAACGCGCTATTGCCGTTGCTCGGCGGCAAAGAAAACATAGCCAGTGCCGCCCACTGCGC
CACACGCTTGCGCCTGGTGCTGCTCGATGACAGCAAGGTGGACAAAGTGGCGATCGGCAAGCTGGAAGGGGTGAAAGGCT
GCTTTAGCAACGCCGGGCAAATCCAGGTGATTTTCGGTACCGGGCTGGTCAACAAGGTGCACGCGGAGTTTATCAAGGCG
GCCGGCGTCAGCGAGTCCAGCAAGTCTGAGGCCGCCGATATCGCGGCGAAAAAACTCAACCCGCTGCAGCGCATTGCCCG
CCTGCTGTCGAATATCTTTGTGCCAATCATCCCGGCTATCGTCGCCTCCGGCCTGCTGATGGGCCTGCTCGGCATGGTGA
AAACCTACGGCTGGGCCGATGCCAACAGCGCCGTATTCGTGATGCTGGATATGTTCAGTTCAGCGGCATTTATTATTTTA
CCAATCCTGATCGGCTTCACCGCCGCGCGTGAATTTGGTGGTAACCCCTATCTGGGCGCTACGCTCGGCGGCATTCTGAC
CCATCCGGCTCTGACCAACGCCTGGGGCGTCGCCAGCGGTTTTCACACCATGGATTTCTTCGGGTTGCAGATTGCCATGA
TCGGCTATCAGGGCACGGTGTTCCCGGTGCTGTTGACGGTGTGGTTTATGAGCATGCTGGAAAAACAGCTGCGCAGAGTG
ATCCCCAATTCGCTGGATCTGATCCTGACGCCGTTCCTGACGGTGGTGATCTCCGGCTTCGTCGCCATGTTGTTTATCGG
CCCGGCCGGTCGCGCGCTGGGTGATGGCATCTCGCTGGTGCTCAGCACGCTGATCGCCCACGCCGGTTGGTTTGCCGGCT
TGCTGTTCGGTGGCCTGTATTCCGCCATCGTCATCACCGGTATCCACCACAGTTTCCATGCCGTCGAAGCCGGACTGCTC
GGCAATCCAAATATCGGCGTTAACTTCCTGCTGCCGATCTGGTCGATGGCCAATATCGCTCAGGGCGGTGCCTGTCTGGC
GGTCTATTTCAAAACCCGCGACGCCAAGATCAAAGCCATCGCGGTGCCTTCGGCCTTTTCCGCCATGCTTGGCATTACCG
AAGCGGCGCTGTTCGGCATTAACCTGCGCTTTGTGAAACCCTTCCTGGCGGCGCTGGCCGGCGGTGCGCTCGGCGGTGCC
TGGGTGGTGGCCAATCACGTCGGCATGAACGCGGTCGGGCTGACGGCAATTCCGGGCATGGCCATTGTGCAGGCCAGTTC
GCTGGTCAGCTATATCATTGGTTTGGTGATCGCCTTCGGCAGCGCCTTTATTATCTCGTTGCTGCTGAAATACAAAACGG
ACAGCGAATAA

Upstream 100 bases:

>100_bases
ACGGCGTACGTGCCCGGTTCAAGTACTTCTTCTGACGCTGATGAACTGATTTCCGCCGCGAAACACCGCGGCGGCATTTT
TATTGATTAAGGGAGTGAAC

Downstream 100 bases:

>100_bases
TGGAAGAATTGAATTTGATGAAACAGGCCGTTCAGGCGTTGATGCGCGACATGCCAAAGGTACTGCGTGCGCCGCACCGC
CCGGCGTGGCATCTGGCGCC

Product: PTS system sucrose-specific transporter subunit IIBC

Products: NA

Alternate protein names: EIIBC-Scr; EII-Scr; Sucrose-specific phosphotransferase enzyme IIB component; PTS system sucrose-specific EIIB component; Sucrose permease IIC component; PTS system sucrose-specific EIIC component [H]

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MDITATANALLPLLGGKENIASAAHCATRLRLVLLDDSKVDKVAIGKLEGVKGCFSNAGQIQVIFGTGLVNKVHAEFIKA
AGVSESSKSEAADIAAKKLNPLQRIARLLSNIFVPIIPAIVASGLLMGLLGMVKTYGWADANSAVFVMLDMFSSAAFIIL
PILIGFTAAREFGGNPYLGATLGGILTHPALTNAWGVASGFHTMDFFGLQIAMIGYQGTVFPVLLTVWFMSMLEKQLRRV
IPNSLDLILTPFLTVVISGFVAMLFIGPAGRALGDGISLVLSTLIAHAGWFAGLLFGGLYSAIVITGIHHSFHAVEAGLL
GNPNIGVNFLLPIWSMANIAQGGACLAVYFKTRDAKIKAIAVPSAFSAMLGITEAALFGINLRFVKPFLAALAGGALGGA
WVVANHVGMNAVGLTAIPGMAIVQASSLVSYIIGLVIAFGSAFIISLLLKYKTDSE

Sequences:

>Translated_456_residues
MDITATANALLPLLGGKENIASAAHCATRLRLVLLDDSKVDKVAIGKLEGVKGCFSNAGQIQVIFGTGLVNKVHAEFIKA
AGVSESSKSEAADIAAKKLNPLQRIARLLSNIFVPIIPAIVASGLLMGLLGMVKTYGWADANSAVFVMLDMFSSAAFIIL
PILIGFTAAREFGGNPYLGATLGGILTHPALTNAWGVASGFHTMDFFGLQIAMIGYQGTVFPVLLTVWFMSMLEKQLRRV
IPNSLDLILTPFLTVVISGFVAMLFIGPAGRALGDGISLVLSTLIAHAGWFAGLLFGGLYSAIVITGIHHSFHAVEAGLL
GNPNIGVNFLLPIWSMANIAQGGACLAVYFKTRDAKIKAIAVPSAFSAMLGITEAALFGINLRFVKPFLAALAGGALGGA
WVVANHVGMNAVGLTAIPGMAIVQASSLVSYIIGLVIAFGSAFIISLLLKYKTDSE
>Mature_456_residues
MDITATANALLPLLGGKENIASAAHCATRLRLVLLDDSKVDKVAIGKLEGVKGCFSNAGQIQVIFGTGLVNKVHAEFIKA
AGVSESSKSEAADIAAKKLNPLQRIARLLSNIFVPIIPAIVASGLLMGLLGMVKTYGWADANSAVFVMLDMFSSAAFIIL
PILIGFTAAREFGGNPYLGATLGGILTHPALTNAWGVASGFHTMDFFGLQIAMIGYQGTVFPVLLTVWFMSMLEKQLRRV
IPNSLDLILTPFLTVVISGFVAMLFIGPAGRALGDGISLVLSTLIAHAGWFAGLLFGGLYSAIVITGIHHSFHAVEAGLL
GNPNIGVNFLLPIWSMANIAQGGACLAVYFKTRDAKIKAIAVPSAFSAMLGITEAALFGINLRFVKPFLAALAGGALGGA
WVVANHVGMNAVGLTAIPGMAIVQASSLVSYIIGLVIAFGSAFIISLLLKYKTDSE

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. This

COG id: COG1263

COG function: function code G; Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI2367362, Length=432, Percent_Identity=33.1018518518519, Blast_Score=242, Evalue=3e-65,
Organism=Escherichia coli, GI1790159, Length=461, Percent_Identity=31.4533622559653, Blast_Score=218, Evalue=8e-58,
Organism=Escherichia coli, GI1788769, Length=477, Percent_Identity=32.9140461215933, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI48994906, Length=464, Percent_Identity=28.8793103448276, Blast_Score=175, Evalue=6e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018113
- InterPro:   IPR004719
- InterPro:   IPR001996
- InterPro:   IPR003352
- InterPro:   IPR013013
- InterPro:   IPR011535
- InterPro:   IPR010973 [H]

Pfam domain/function: PF00367 PTS_EIIB; PF02378 PTS_EIIC [H]

EC number: =2.7.1.69 [H]

Molecular weight: Translated: 47616; Mature: 47616

Theoretical pI: Translated: 9.52; Mature: 9.52

Prosite motif: PS01035 PTS_EIIB_TYPE_1_CYS ; PS51098 PTS_EIIB_TYPE_1 ; PS51103 PTS_EIIC_TYPE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDITATANALLPLLGGKENIASAAHCATRLRLVLLDDSKVDKVAIGKLEGVKGCFSNAGQ
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCE
IQVIFGTGLVNKVHAEFIKAAGVSESSKSEAADIAAKKLNPLQRIARLLSNIFVPIIPAI
EEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VASGLLMGLLGMVKTYGWADANSAVFVMLDMFSSAAFIILPILIGFTAAREFGGNPYLGA
HHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHH
TLGGILTHPALTNAWGVASGFHTMDFFGLQIAMIGYQGTVFPVLLTVWFMSMLEKQLRRV
HHHHHHHCCCHHCCCCCCCCCHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
IPNSLDLILTPFLTVVISGFVAMLFIGPAGRALGDGISLVLSTLIAHAGWFAGLLFGGLY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIVITGIHHSFHAVEAGLLGNPNIGVNFLLPIWSMANIAQGGACLAVYFKTRDAKIKAI
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
AVPSAFSAMLGITEAALFGINLRFVKPFLAALAGGALGGAWVVANHVGMNAVGLTAIPGM
ECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCHHHCCCH
AIVQASSLVSYIIGLVIAFGSAFIISLLLKYKTDSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDITATANALLPLLGGKENIASAAHCATRLRLVLLDDSKVDKVAIGKLEGVKGCFSNAGQ
CCCCCCHHHHHHHCCCCHHHHHHHHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHCCCCE
IQVIFGTGLVNKVHAEFIKAAGVSESSKSEAADIAAKKLNPLQRIARLLSNIFVPIIPAI
EEEEEECCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VASGLLMGLLGMVKTYGWADANSAVFVMLDMFSSAAFIILPILIGFTAAREFGGNPYLGA
HHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHCHHHHHHHHHHHHHHHHHCCCCCCHHH
TLGGILTHPALTNAWGVASGFHTMDFFGLQIAMIGYQGTVFPVLLTVWFMSMLEKQLRRV
HHHHHHHCCCHHCCCCCCCCCHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHH
IPNSLDLILTPFLTVVISGFVAMLFIGPAGRALGDGISLVLSTLIAHAGWFAGLLFGGLY
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SAIVITGIHHSFHAVEAGLLGNPNIGVNFLLPIWSMANIAQGGACLAVYFKTRDAKIKAI
HHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCEEEEE
AVPSAFSAMLGITEAALFGINLRFVKPFLAALAGGALGGAWVVANHVGMNAVGLTAIPGM
ECCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHEECCCCCCCCCHHHCCCH
AIVQASSLVSYIIGLVIAFGSAFIISLLLKYKTDSE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8628219 [H]