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The map label for this gene is yicI [C]

Identifier: 157371833

GI number: 157371833

Start: 3975647

End: 3978019

Strand: Reverse

Name: yicI [C]

Synonym: Spro_3598

Alternate gene names: 157371833

Gene position: 3978019-3975647 (Counterclockwise)

Preceding gene: 157371834

Following gene: 157371831

Centisome position: 73.01

GC content: 59.54

Gene sequence:

>2373_bases
ATGCCTATGAAAACCTTAAAAAATTGGACGTTGGCCGGTCAGTATGCCGATCGCATTGAGCTGTTGGTCGATGAACGTCA
CCTGTTCTGCCTGTACGTGCTGGAAAACAGCCTGTTCCGCGTGTTGATTAAACGCAATGGCGAGTTGGCGCTGGATCGCA
CCTGGAGCATTGCGCCGCAGACTGATGTGCCCTGGGAAGGGCGTGATCGTTTGAGCGTGGCCGGCTTCGGCCTGCCGGGT
TATCAGTTGCAGCAACATGAGGATCGGCTGGTGGTGACGACGTCTGCACTGCGCGTTACCGTGCATCAGCCGCTGTGGCT
GGAGTGGGAGCACTGCAACGCCGCCGGTGAATGGCGTCCGCTGGCCGCCGATCGGCCAACCAGCGCTTACCTGCTGAACC
CGCACGGTGACGGCGTGGCCCACTACCAGCGCCGTCAGGCCGCCGAGCGGTACTATGGCCTGGGTGAGAAGGCCGGTGAT
TTGGAGCGTAGCGGTCGCCGCTTTGAAATGCGCAACCTGGACGCGATGGGTTACAACGCCGCCAGCACCGATCCGCTGTA
CAAGCACATTCCTTTCACCATCACCCGTGGGGAAGAGGCCAGTTTCGGGCTGTTTTACGACAACCTGAGCAGTTGCTGGC
TGGATCTGGGCAATGAGATCGATAACTACCATCTGGCCTATCGCCGCTATCAGGCCGAAGCGGGGGATCTGGATTATTAC
CTGTTCCTCGGCCCCAAAGTGCTGGACGTGACCAAGGCGTTTGTACGCCTGACCGGCAAGACTCACTTCGGCCCGAAATG
GAGCCTGGGCTACAGCGGTTCCACCATGCATTACACCGATGCGCCGGACGCCCAGCAGCAGCTACAGCAGTTTATTCAGC
TCTGTCGCCAGCATGATATTCCCTGCGACTCGTTCCAACTGTCGTCGGGTTATACCTCGATCGGCAACAAGCGCTATGTA
TTCAACTGGAACTACGACAAGGTGCCGCAGCCCAAACAGCTGAGCCAGGCATTTCACGACGCCGGGTTAAAGCTGGCGGC
CAACATCAAGCCGTGCCTGTTGCATGATCATCCGCAGTATCAGCAGGCGGCGGAGCAGGGGTTGTTTATCCGGGATTCCG
AAAGTGACCGGCCGGAGCGCTCCAGCTTTTGGGACGACGAAGGCTCGCACCTCGACTTCACCAATCCGGCGGCGGTGCAA
TGGTGGCAACAGGGCGTGACGCAGCAGCTGCTGGAGATGGGCATTGATTCCACCTGGAATGACAATAACGAATACGAAGT
GTGGGACGGAGAGGCGCGTTGCCACGGTTTTGGCACGCCTATCGCCATCAAGCATATCCGCCCGGTGATGCCGTTACTGA
TGATGCGCGCTTCAATGGAGGCTCAGCAACGCTTTGCTCCCGAGCTGCGGCCTTACCTGATCTCGCGTTCCGGTTGCGCC
GGTATGCAGCGTTATGTGCAGACCTGGAGCGGCGACAACCGCACCAACTGGCAGACTTTGCGTTACAACATCCGTATGGG
GTTGGGCATGAGCCTGTCTGGCCTGTATAACCTGGGGCACGACGTCGGCGGTTTCTCCGGTGACAAGCCGGACGCCGAGC
TTCTGGTGCGCTGGGTGCAAAACGGCGTGATGCATCCGCGTTTTACCATTCACTCCTGGAACGACGACGCCACGGTGAAT
GAACCCTGGATGTATCCGGCCGCTACCCCGGCGGTACGCGAGGCGATTAACCTGCGTTACCGGCTGATGCCGTATTTCTA
CACCCTGCTGTGGCAGGCCAGTGCCGACGACGAGCCGATGCTGCGCCCGACTTTCCTCGACCATGAGCATGACGAGCAGA
CCCTGAAAGAAACCGATGATTTTATGATTGGTCGCGATCTGCTGGTGGCCAGCGTAGTGGAGCAGGGGCAACGCCAGCGG
CCGGTGTATCTGCCGGATAACGGCGATGGTTGGTATTGCTTCTACAGCGGCCAGTGGTTCAGTGGCGGCCAGACGGTGAT
GCTGGAAGCCCCGCTGGAGCGCTTGCCGCTGCTGGTGCGTGCCGGTGCGGCATTGCCGTTGTCATCCCGCCTGGCGCATG
TTGACGTAACGGCGGACGATCGACGTGAGCTTAAGTTGTACCCGCTAAAAGGCTGTGGCAGCGCTTCTGGGCTGTTATTT
GAAGACGACGGCGAGAGTTATGGCTGGCAGCAGGGCGACGCGCTGTGGCTGCGCTGGGAGATGCTCAGTGACAATCAGCG
CATCACGCTGAACCTCACCACTGAGGGTCGCTTTAAACCGGCATGGCGAACCATCACCTTCAGCTTGCCTGCCGGAGAAG
CGCGCGAGTTGTGGATCAACGGCGCGCCCGGCAACAGTTTTACGCTGGAATAA

Upstream 100 bases:

>100_bases
TGTTTATCGCCATGGGCTTCTTCGACCTGATCGGCGCCGTATTCCTGATTGCCTTGATCGCCGAACGTGGCGGTAAAAAA
ACACTTAATAGTTAAGTTGG

Downstream 100 bases:

>100_bases
GCGGAATTATTCAGCCGCGCGCTTTTTGCGCGGTTTTTTGGCCAGGGTGATGGTTTTCACCTCGCTTTCCACCCAGCCAT
CCTGCAGACGGGTTTTCAGC

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 790; Mature: 789

Protein sequence:

>790_residues
MPMKTLKNWTLAGQYADRIELLVDERHLFCLYVLENSLFRVLIKRNGELALDRTWSIAPQTDVPWEGRDRLSVAGFGLPG
YQLQQHEDRLVVTTSALRVTVHQPLWLEWEHCNAAGEWRPLAADRPTSAYLLNPHGDGVAHYQRRQAAERYYGLGEKAGD
LERSGRRFEMRNLDAMGYNAASTDPLYKHIPFTITRGEEASFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYY
LFLGPKVLDVTKAFVRLTGKTHFGPKWSLGYSGSTMHYTDAPDAQQQLQQFIQLCRQHDIPCDSFQLSSGYTSIGNKRYV
FNWNYDKVPQPKQLSQAFHDAGLKLAANIKPCLLHDHPQYQQAAEQGLFIRDSESDRPERSSFWDDEGSHLDFTNPAAVQ
WWQQGVTQQLLEMGIDSTWNDNNEYEVWDGEARCHGFGTPIAIKHIRPVMPLLMMRASMEAQQRFAPELRPYLISRSGCA
GMQRYVQTWSGDNRTNWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPDAELLVRWVQNGVMHPRFTIHSWNDDATVN
EPWMYPAATPAVREAINLRYRLMPYFYTLLWQASADDEPMLRPTFLDHEHDEQTLKETDDFMIGRDLLVASVVEQGQRQR
PVYLPDNGDGWYCFYSGQWFSGGQTVMLEAPLERLPLLVRAGAALPLSSRLAHVDVTADDRRELKLYPLKGCGSASGLLF
EDDGESYGWQQGDALWLRWEMLSDNQRITLNLTTEGRFKPAWRTITFSLPAGEARELWINGAPGNSFTLE

Sequences:

>Translated_790_residues
MPMKTLKNWTLAGQYADRIELLVDERHLFCLYVLENSLFRVLIKRNGELALDRTWSIAPQTDVPWEGRDRLSVAGFGLPG
YQLQQHEDRLVVTTSALRVTVHQPLWLEWEHCNAAGEWRPLAADRPTSAYLLNPHGDGVAHYQRRQAAERYYGLGEKAGD
LERSGRRFEMRNLDAMGYNAASTDPLYKHIPFTITRGEEASFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYY
LFLGPKVLDVTKAFVRLTGKTHFGPKWSLGYSGSTMHYTDAPDAQQQLQQFIQLCRQHDIPCDSFQLSSGYTSIGNKRYV
FNWNYDKVPQPKQLSQAFHDAGLKLAANIKPCLLHDHPQYQQAAEQGLFIRDSESDRPERSSFWDDEGSHLDFTNPAAVQ
WWQQGVTQQLLEMGIDSTWNDNNEYEVWDGEARCHGFGTPIAIKHIRPVMPLLMMRASMEAQQRFAPELRPYLISRSGCA
GMQRYVQTWSGDNRTNWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPDAELLVRWVQNGVMHPRFTIHSWNDDATVN
EPWMYPAATPAVREAINLRYRLMPYFYTLLWQASADDEPMLRPTFLDHEHDEQTLKETDDFMIGRDLLVASVVEQGQRQR
PVYLPDNGDGWYCFYSGQWFSGGQTVMLEAPLERLPLLVRAGAALPLSSRLAHVDVTADDRRELKLYPLKGCGSASGLLF
EDDGESYGWQQGDALWLRWEMLSDNQRITLNLTTEGRFKPAWRTITFSLPAGEARELWINGAPGNSFTLE
>Mature_789_residues
PMKTLKNWTLAGQYADRIELLVDERHLFCLYVLENSLFRVLIKRNGELALDRTWSIAPQTDVPWEGRDRLSVAGFGLPGY
QLQQHEDRLVVTTSALRVTVHQPLWLEWEHCNAAGEWRPLAADRPTSAYLLNPHGDGVAHYQRRQAAERYYGLGEKAGDL
ERSGRRFEMRNLDAMGYNAASTDPLYKHIPFTITRGEEASFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYYL
FLGPKVLDVTKAFVRLTGKTHFGPKWSLGYSGSTMHYTDAPDAQQQLQQFIQLCRQHDIPCDSFQLSSGYTSIGNKRYVF
NWNYDKVPQPKQLSQAFHDAGLKLAANIKPCLLHDHPQYQQAAEQGLFIRDSESDRPERSSFWDDEGSHLDFTNPAAVQW
WQQGVTQQLLEMGIDSTWNDNNEYEVWDGEARCHGFGTPIAIKHIRPVMPLLMMRASMEAQQRFAPELRPYLISRSGCAG
MQRYVQTWSGDNRTNWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPDAELLVRWVQNGVMHPRFTIHSWNDDATVNE
PWMYPAATPAVREAINLRYRLMPYFYTLLWQASADDEPMLRPTFLDHEHDEQTLKETDDFMIGRDLLVASVVEQGQRQRP
VYLPDNGDGWYCFYSGQWFSGGQTVMLEAPLERLPLLVRAGAALPLSSRLAHVDVTADDRRELKLYPLKGCGSASGLLFE
DDGESYGWQQGDALWLRWEMLSDNQRITLNLTTEGRFKPAWRTITFSLPAGEARELWINGAPGNSFTLE

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI38202257, Length=677, Percent_Identity=29.2466765140325, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI88900491, Length=677, Percent_Identity=29.2466765140325, Blast_Score=271, Evalue=2e-72,
Organism=Homo sapiens, GI66346737, Length=598, Percent_Identity=29.4314381270903, Blast_Score=249, Evalue=8e-66,
Organism=Homo sapiens, GI119393895, Length=616, Percent_Identity=26.6233766233766, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI119393893, Length=616, Percent_Identity=26.6233766233766, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI119393891, Length=616, Percent_Identity=26.6233766233766, Blast_Score=164, Evalue=3e-40,
Organism=Homo sapiens, GI221316699, Length=564, Percent_Identity=23.936170212766, Blast_Score=154, Evalue=3e-37,
Organism=Homo sapiens, GI157364974, Length=645, Percent_Identity=24.8062015503876, Blast_Score=150, Evalue=6e-36,
Organism=Homo sapiens, GI310115361, Length=271, Percent_Identity=30.2583025830258, Blast_Score=103, Evalue=1e-21,
Organism=Escherichia coli, GI2367256, Length=577, Percent_Identity=25.1299826689775, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI2367323, Length=383, Percent_Identity=27.154046997389, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71991189, Length=635, Percent_Identity=30.0787401574803, Blast_Score=267, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17560800, Length=639, Percent_Identity=27.6995305164319, Blast_Score=233, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI17560798, Length=639, Percent_Identity=27.6995305164319, Blast_Score=233, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI32563849, Length=277, Percent_Identity=30.6859205776173, Blast_Score=126, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71985706, Length=621, Percent_Identity=23.5104669887279, Blast_Score=117, Evalue=3e-26,
Organism=Saccharomyces cerevisiae, GI6319706, Length=603, Percent_Identity=27.1973466003317, Blast_Score=207, Evalue=6e-54,
Organism=Drosophila melanogaster, GI24643749, Length=657, Percent_Identity=26.9406392694064, Blast_Score=222, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24643753, Length=657, Percent_Identity=26.9406392694064, Blast_Score=222, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24643751, Length=657, Percent_Identity=26.9406392694064, Blast_Score=222, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24643746, Length=657, Percent_Identity=26.9406392694064, Blast_Score=222, Evalue=1e-57,
Organism=Drosophila melanogaster, GI21357605, Length=657, Percent_Identity=26.9406392694064, Blast_Score=222, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24650054, Length=371, Percent_Identity=24.7978436657682, Blast_Score=80, Evalue=8e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 90434; Mature: 90302

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: PS00066 HMG_COA_REDUCTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMKTLKNWTLAGQYADRIELLVDERHLFCLYVLENSLFRVLIKRNGELALDRTWSIAPQ
CCCCCCCCCEEECCHHHHEEEEECCCCEEEEEEHHHHHHHHHHHCCCCEEEECEEECCCC
TDVPWEGRDRLSVAGFGLPGYQLQQHEDRLVVTTSALRVTVHQPLWLEWEHCNAAGEWRP
CCCCCCCCCCEEEEECCCCCCHHHCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCCCCC
LAADRPTSAYLLNPHGDGVAHYQRRQAAERYYGLGEKAGDLERSGRRFEMRNLDAMGYNA
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCCCCC
ASTDPLYKHIPFTITRGEEASFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYY
CCCCCHHHCCCEEEECCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEEHEEECCCCCCEEE
LFLGPKVLDVTKAFVRLTGKTHFGPKWSLGYSGSTMHYTDAPDAQQQLQQFIQLCRQHDI
EEECCHHHHHHHHHHHCCCCCCCCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCC
PCDSFQLSSGYTSIGNKRYVFNWNYDKVPQPKQLSQAFHDAGLKLAANIKPCLLHDHPQY
CCCCEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCEEECCCCHH
QQAAEQGLFIRDSESDRPERSSFWDDEGSHLDFTNPAAVQWWQQGVTQQLLEMGIDSTWN
HHHHHCCCEEECCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC
DNNEYEVWDGEARCHGFGTPIAIKHIRPVMPLLMMRASMEAQQRFAPELRPYLISRSGCA
CCCCEEEECCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCHH
GMQRYVQTWSGDNRTNWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPDAELLVRWVQ
HHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
NGVMHPRFTIHSWNDDATVNEPWMYPAATPAVREAINLRYRLMPYFYTLLWQASADDEPM
CCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
LRPTFLDHEHDEQTLKETDDFMIGRDLLVASVVEQGQRQRPVYLPDNGDGWYCFYSGQWF
CCCEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCEEE
SGGQTVMLEAPLERLPLLVRAGAALPLSSRLAHVDVTADDRRELKLYPLKGCGSASGLLF
CCCCEEEEECCHHHCCEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEE
EDDGESYGWQQGDALWLRWEMLSDNQRITLNLTTEGRFKPAWRTITFSLPAGEARELWIN
CCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEE
GAPGNSFTLE
CCCCCCCCCC
>Mature Secondary Structure 
PMKTLKNWTLAGQYADRIELLVDERHLFCLYVLENSLFRVLIKRNGELALDRTWSIAPQ
CCCCCCCCEEECCHHHHEEEEECCCCEEEEEEHHHHHHHHHHHCCCCEEEECEEECCCC
TDVPWEGRDRLSVAGFGLPGYQLQQHEDRLVVTTSALRVTVHQPLWLEWEHCNAAGEWRP
CCCCCCCCCCEEEEECCCCCCHHHCCCCCEEEEEEEEEEEECCCEEEEECCCCCCCCCCC
LAADRPTSAYLLNPHGDGVAHYQRRQAAERYYGLGEKAGDLERSGRRFEMRNLDAMGYNA
CCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCCCCC
ASTDPLYKHIPFTITRGEEASFGLFYDNLSSCWLDLGNEIDNYHLAYRRYQAEAGDLDYY
CCCCCHHHCCCEEEECCCCCCEEEEHHHHHHHHHHHCCCCCCCEEEEHEEECCCCCCEEE
LFLGPKVLDVTKAFVRLTGKTHFGPKWSLGYSGSTMHYTDAPDAQQQLQQFIQLCRQHDI
EEECCHHHHHHHHHHHCCCCCCCCCCEECCCCCCEEEECCCCCHHHHHHHHHHHHHHCCC
PCDSFQLSSGYTSIGNKRYVFNWNYDKVPQPKQLSQAFHDAGLKLAANIKPCLLHDHPQY
CCCCEEECCCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCEEEECCCCEEECCCCHH
QQAAEQGLFIRDSESDRPERSSFWDDEGSHLDFTNPAAVQWWQQGVTQQLLEMGIDSTWN
HHHHHCCCEEECCCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHCCCCCCC
DNNEYEVWDGEARCHGFGTPIAIKHIRPVMPLLMMRASMEAQQRFAPELRPYLISRSGCA
CCCCEEEECCCCEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEECCCCHH
GMQRYVQTWSGDNRTNWQTLRYNIRMGLGMSLSGLYNLGHDVGGFSGDKPDAELLVRWVQ
HHHHHHHHHCCCCCCCEEEEEEEEEECCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHH
NGVMHPRFTIHSWNDDATVNEPWMYPAATPAVREAINLRYRLMPYFYTLLWQASADDEPM
CCCCCCEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCC
LRPTFLDHEHDEQTLKETDDFMIGRDLLVASVVEQGQRQRPVYLPDNGDGWYCFYSGQWF
CCCEECCCCCCHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEEECCEEE
SGGQTVMLEAPLERLPLLVRAGAALPLSSRLAHVDVTADDRRELKLYPLKGCGSASGLLF
CCCCEEEEECCHHHCCEEEECCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCEE
EDDGESYGWQQGDALWLRWEMLSDNQRITLNLTTEGRFKPAWRTITFSLPAGEARELWIN
CCCCCCCCCCCCCEEEEEEEEECCCCEEEEEEECCCCCCCCEEEEEEECCCCCCEEEEEE
GAPGNSFTLE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]